MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Cho, Eun Gyung ^a   Zaremba, Jeffrey D ^a   McKercher, Scott R ^a   Talantova, Maria ^a   Tu, Shichun ^a   Masliah, Eliezer ^b   Chan, Shing Fai ^a   Nakanishi, Nobuki ^a   Terskikh, Alexey ^a   Lipton, Stuart A ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; CELL PROTEIN; ENGRAILED 1 PROTEIN; LENTIVIRUS VECTOR; MYOCYTE ENHANCER FACTOR 2; MYOCYTE ENHANCER FACTOR 2A; MYOCYTE ENHANCER FACTOR 2C; MYOCYTE ENHANCER FACTOR 2D; NEURON SPECIFIC NUCLEAR PROTEIN; NUCLEAR RECEPTOR RELATED FACTOR 1; OXIDOPAMINE; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN BCL XL; PROTEIN S100B; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2; MADS DOMAIN PROTEIN; MEF2C PROTEIN, HUMAN; MYOGENIC FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC SPINE; DISEASE MODEL; DOPAMINERGIC NERVE CELL; EMBRYONIC STEM CELL; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOTOR PERFORMANCE; NERVE CELL DIFFERENTIATION; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; OLIGODENDROGLIA; PARKINSON DISEASE; PROTEIN ENGINEERING; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; STEM CELL TRANSPLANTATION; VIRAL GENE DELIVERY SYSTEM; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; ELECTROPHYSIOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; NICK END LABELING; PHYSIOLOGY; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSPLANTATION;

PARKINSONIA; RATTUS;

ANIMALS; CELL DIFFERENTIATION; DOPAMINERGIC NEURONS; ELECTROPHYSIOLOGY; EMBRYONIC STEM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MADS DOMAIN PROTEINS; MYOGENIC REGULATORY FACTORS; NEUROGENESIS; OXIDOPAMINE; PARKINSON DISEASE; POLYMERASE CHAIN REACTION; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 80052049289     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024027     Document Type: Article

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