A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by aurora kinases

Current Biology

Volumn 21, Issue 16, 2011, Pages 1356-1365

  Tanenbaum, Marvin E ^a   MacUrek, Libor ^a,b   Van Der Vaart, Babet ^c   Galli, Matilde ^d   Akhmanova, Anna ^c,d   Medema, René H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA KINASE; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CYSTEINE PROTEINASE INHIBITOR; EB1 MICROTUBULE BINDING PROTEINS; HYBRID PROTEIN; KIF18B PROTEIN, HUMAN; KIF2C PROTEIN, HUMAN; KINESIN; LEUPEPTIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA;

ARTICLE; CELL LINE; GENETICS; HUMAN; METABOLISM; MICROTUBULE; MITOSIS; PHYSIOLOGY; PROTEIN BINDING;

CELL LINE; CYSTEINE PROTEINASE INHIBITORS; HUMANS; KINESIN; LEUPEPTINS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOSIS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING;

EID: 80052033722     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2011.07.017     Document Type: Article

References (39)

1. J. Howard, and A.A. Hyman Microtubule polymerases and depolymerases Curr. Opin. Cell Biol. 19 2007 31 35 (Pubitemid 46138038)
2. C.E. Walczak The Kin I kinesins are microtubule end-stimulated ATPases Mol. Cell 11 2003 286 288 (Pubitemid 36293822)
3. L. Wordeman Microtubule-depolymerizing kinesins Curr. Opin. Cell Biol. 17 2005 82 88 (Pubitemid 40138092)
4. A. Desai, S. Verma, T.J. Mitchison, and C.E. Walczak Kin I kinesins are microtubule-destabilizing enzymes Cell 96 1999 69 78 (Pubitemid 29044154)
5. J. Helenius, G. Brouhard, Y. Kalaidzidis, S. Diez, and J. Howard The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends Nature 441 2006 115 119
6. A. Akhmanova, and C.C. Hoogenraad Microtubule plus-end-tracking proteins: Mechanisms and functions Curr. Opin. Cell Biol. 17 2005 47 54 (Pubitemid 40138087)
7. A.T. Moore, K.E. Rankin, G. von Dassow, L. Peris, M. Wagenbach, Y. Ovechkina, A. Andrieux, D. Job, and L. Wordeman MCAK associates with the tips of polymerizing microtubules J. Cell Biol. 169 2005 391 397 (Pubitemid 40686689)
8. T. Lee, K.J. Langford, J.M. Askham, A. Brüning-Richardson, and E.E. Morrison MCAK associates with EB1 Oncogene 27 2008 2494 2500 (Pubitemid 351521088)
9. S. Montenegro Gouveia, K. Leslie, L.C. Kapitein, R.M. Buey, I. Grigoriev, M. Wagenbach, I. Smal, E. Meijering, C.C. Hoogenraad, and L. Wordeman In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends Curr. Biol. 20 2010 1717 1722
10. M.L. Gupta Jr., P. Carvalho, D.M. Roof, and D. Pellman Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle Nat. Cell Biol. 8 2006 913 923 (Pubitemid 44314722)
11. M.I. Mayr, S. Hümmer, J. Bormann, T. Grüner, S. Adio, G. Woehlke, and T.U. Mayer The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression Curr. Biol. 17 2007 488 498 (Pubitemid 46401386)
12. V. Varga, J. Helenius, K. Tanaka, A.A. Hyman, T.U. Tanaka, and J. Howard Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner Nat. Cell Biol. 8 2006 957 962 (Pubitemid 44314726)
13. V. Varga, C. Leduc, V. Bormuth, S. Diez, and J. Howard Kinesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization Cell 138 2009 1174 1183
14. M.S. Savoian, M.K. Gatt, M.G. Riparbelli, G. Callaini, and D.M. Glover Drosophila Klp67A is required for proper chromosome congression and segregation during meiosis I J. Cell Sci. 117 2004 3669 3677 (Pubitemid 39206406)
15. R. Gandhi, S. Bonaccorsi, D. Wentworth, S. Doxsey, M. Gatti, and A. Pereira The Drosophila kinesin-like protein KLP67A is essential for mitotic and male meiotic spindle assembly Mol. Biol. Cell 15 2004 121 131 (Pubitemid 38044949)
16. R.R. West, T. Malmstrom, C.L. Troxell, and J.R. McIntosh Two related kinesins, klp5+ and klp6+, foster microtubule disassembly and are required for meiosis in fission yeast Mol. Biol. Cell 12 2001 3919 3932 (Pubitemid 34001082)
17. A.R. Barr, and F. Gergely Aurora-A: The maker and breaker of spindle poles J. Cell Sci. 120 2007 2987 2996 (Pubitemid 47517082)
18. B.S. Tseng, L. Tan, T.M. Kapoor, and H. Funabiki Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly Dev. Cell 18 2010 903 912
19. M.A. Lampson, and I.M. Cheeseman Sensing centromere tension: Aurora B and the regulation of kinetochore function Trends Cell Biol. 21 2011 133 140
20. S. Ruchaud, M. Carmena, and W.C. Earnshaw Chromosomal passengers: Conducting cell division Nat. Rev. Mol. Cell Biol. 8 2007 798 812 (Pubitemid 47462135)
21. G. Vader, R.H. Medema, and S.M. Lens The chromosomal passenger complex: Guiding Aurora-B through mitosis J. Cell Biol. 173 2006 833 837
22. P.D. Andrews, Y. Ovechkina, N. Morrice, M. Wagenbach, K. Duncan, L. Wordeman, and J.R. Swedlow Aurora B regulates MCAK at the mitotic centromere Dev. Cell 6 2004 253 268 (Pubitemid 38190365)
23. W. Lan, X. Zhang, S.L. Kline-Smith, S.E. Rosasco, G.A. Barrett-Wilt, J. Shabanowitz, D.F. Hunt, C.E. Walczak, and P.T. Stukenberg Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity Curr. Biol. 14 2004 273 286 (Pubitemid 38300205)
24. R. Ohi, T. Sapra, J. Howard, and T.J. Mitchison Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation Mol. Biol. Cell 15 2004 2895 2906 (Pubitemid 38691877)
25. X. Zhang, S.C. Ems-McClung, and C.E. Walczak Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity Mol. Biol. Cell 19 2008 2752 2765
26. M.E. Tanenbaum, L. Macrek, A. Janssen, E.F. Geers, M. Alvarez-Fernández, and R.H. Medema Kif15 cooperates with eg5 to promote bipolar spindle assembly Curr. Biol. 19 2009 1703 1711
27. M.E. Tanenbaum, N. Galjart, M.A. van Vugt, and R.H. Medema CLIP-170 facilitates the formation of kinetochore-microtubule attachments EMBO J. 25 2006 45 57 (Pubitemid 43077294)
28. Y.M. Lee, E. Kim, M. Park, E. Moon, S.M. Ahn, W. Kim, K.B. Hwang, Y.K. Kim, W. Choi, and W. Kim Cell cycle-regulated expression and subcellular localization of a kinesin-8 member human KIF18B Gene 466 2010 16 25
29. J. Stumpff, G. von Dassow, M. Wagenbach, C. Asbury, and L. Wordeman The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment Dev. Cell 14 2008 252 262 (Pubitemid 351189173)
30. A. Akhmanova, and M.O. Steinmetz Tracking the ends: A dynamic protein network controls the fate of microtubule tips Nat. Rev. Mol. Cell Biol. 9 2008 309 322 (Pubitemid 351430849)
31. S. Honnappa, S.M. Gouveia, A. Weisbrich, F.F. Damberger, N.S. Bhavesh, H. Jawhari, I. Grigoriev, F.J. van Rijssel, R.M. Buey, and A. Lawera An EB1-binding motif acts as a microtubule tip localization signal Cell 138 2009 366 376
32. Y. Du, C.A. English, and R. Ohi The kinesin-8 Kif18A dampens microtubule plus-end dynamics Curr. Biol. 20 2010 374 380
33. S. Honnappa, C.M. John, D. Kostrewa, F.K. Winkler, and M.O. Steinmetz Structural insights into the EB1-APC interaction EMBO J. 24 2005 261 269 (Pubitemid 40216131)
34. X. Zhang, W. Lan, S.C. Ems-McClung, P.T. Stukenberg, and C.E. Walczak Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function Mol. Biol. Cell 18 2007 3264 3276 (Pubitemid 47378669)
35. T.P. Barros, K. Kinoshita, A.A. Hyman, and J.W. Raff Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules J. Cell Biol. 170 2005 1039 1046 (Pubitemid 41362636)
36. C.E. Walczak, T.J. Mitchison, and A. Desai XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly Cell 84 1996 37 47 (Pubitemid 26031459)
37. D. Splinter, M.E. Tanenbaum, A. Lindqvist, D. Jaarsma, A. Flotho, K.L. Yu, I. Grigoriev, D. Engelsma, E.D. Haasdijk, and N. Keijzer Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry PLoS Biol. 8 2010 e1000350
38. M.E. Tanenbaum, L. Macrek, N. Galjart, and R.H. Medema Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly EMBO J. 27 2008 3235 3245
39. Y. Komarova, G. Lansbergen, N. Galjart, F. Grosveld, G.G. Borisy, and A. Akhmanova EB1 and EB3 control CLIP dissociation from the ends of growing microtubules Mol. Biol. Cell 16 2005 5334 5345 (Pubitemid 41566843)