Synthesis and evaluation of novel prodrugs of naproxen

Medicinal Chemistry Research

Volumn 20, Issue 5, 2011, Pages 648-655

  Sharma, Prabodh Chander ^a   Yadav, Sonia ^a   Pahwa, Rakesh ^a   Kaushik, Dhirender ^a   Jain, Sandeep ^b  

^a KURUKSHETRA UNIVERSITY   (India)

^b GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Analgesic activity; Anti inflammatory activity; In vitro hydrolytic studies; Naproxen; Prodrugs

Indexed keywords

2 N [6 [1'' METHYL 1'' (6 METHOXYNAPHTH 1 YL)]ETHOXY] 2',3',4',5' TETRAACETYLHEX 1' YL 2 IMINOPROPANOIC ACID; 3 (3,4 DIHYDROXYPHENYL) 2 N [6 [1'' METHYL 1'' (6 METHOXYNAPHTH 1 YL)]ETHOXY] 2',3',4',5' TETRAACETYLHEX 1' YL 2 IMINOPROPANOIC ACID; ACETIC ACID; N [6 [1'' METHYL 1'' (6 METHOXYNAPHTH 1 YL)]ETHOXY] 2',3',4',5' TETRAACETYLHEX 1' YLIMINOETHANOIC ACID; NAPROXEN; NAPROXEN DERIVATIVE; PHOSPHATE; PRODRUG; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; GASTROINTESTINAL TOXICITY; MALE; NONHUMAN; PAW EDEMA; RAT; STOMACH IRRITATION; ULCEROGENESIS;

EID: 80052029882     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9364-8     Document Type: Article

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