Synthesis and properties of copolymers from 2-hydroxyethyl methacrylate-linked nonsteroidal antiinflammatory agents with methacrylic acid

Journal of Polymer Science, Part A: Polymer Chemistry

Volumn 36, Issue 9, 1998, Pages 1481-1490

  Chang, C H ^a   Sheu, Y M ^a   Hu, W P ^a   Wang, L F ^a   Chen, J S ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b I SHOU UNIVERSITY   (Taiwan)

Author keywords

Copolymer reactivity; Ibuprofen; Ketoprofen; Naproxen; Thermal stability

Indexed keywords

CALCULATIONS; COMPOSITION; COMPUTER SIMULATION; COPOLYMERIZATION; DIFFERENTIAL EQUATIONS; DRUG PRODUCTS; GLASS TRANSITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS (CHEMICAL); TEMPERATURE; THERMODYNAMIC STABILITY;

COPOLYMER REACTIVITY; HYDROXYETHYL METHACRYLATE; IBUPROFEN; KETOPROFEN; NAPROXEN; NONSTEROIDAL ANTIINFLAMMATORY AGENTS;

COPOLYMERS;

EID: 0032122997     PISSN: 0887624X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0518(19980715)36:9<1481::AID-POLA16>3.0.CO;2-0     Document Type: Article

References (21)

1. S. Dumitriu, M. Popa, and M. Dumitriu, J. Bioact. Comp. Polym., 4. 111 (1989).
2. F. M. Li, Z. W. Gu, G. W. Li, S. Wang, and X. D. Feng, J. Bioact. Comp. Polym., 6, 142 (1991).
3. S. Dumitriu and M. Popa, J. Bioact. Comp. Polym., 4, 57 (1989).
4. G. Giammona, B. Carlisi, G. Pitarresi, and G. Fontana, J. Bioact. Compat. Polym., 6, 129 (1991).
5. A. Gallardo and J. S. Román, Polymer, 34, 394 (1993).
6. P. A. Liso, M. Rebuelta, J. S. Román, A. Gallardo, and A. M. Villar, J. Biomed. Mater. Res., 32, 553 (1996).
7. C. J. Boudreaux, W. C. Bunyard, and C. L. McCormic, J. Control. Rel., 40, 223 (1996).
8. S. Davaran and A. A. Entezami, J. Control. Rel., 47, 41 (1997).
9. S. Davaran and A. A. Entezami, J. Bioact. Compat. Polym., 6, 47 (1997).
10. M. M. Davies and G. B. B. M. Sutherland, J. Chem. Phys., 6, 755 (1938).
11. R. Longworth and H. Morawetz, J. Polym. Sci., 29, 307 (1958).
12. E. P. Otocka and T. K. Kwei, Macromolecules, 1, 244 (1968).
13. L. Daniliuc and C. David, Polymer, 37, 5219 (1996).
14. H. Blanco-Fuente, S. Anguiano-Igea, F. J. Otero-Espinar, and J. Blanco-Méndez, Biomaterials, 17, 1667 (1996).
15. J. J. Maurer, D. J. Eustace, and G. T. Ratcliffe, Macromolecules, 20, 196 (1987).
16. L. F. Wang, E. M. Pearce, and T. K. Kwei, J. Polym. Sci., Polym. Lett. Ed., 28, 3117 (1990).
17. Biosym Insight II/DISCOVER (version 95.0/2.97) is a molecular modeling software package of Biosym Technologies Inc., Barnes Canyon Rd., San Diego, CA 92121.
18. E. P. Boden and G. E. Keck, J. Org. Chem., 50, 2394 (1985).
19. L. F. Wang and C. H. Chang, to appear.
20. T. Kelen and F. Tüdös, J. Macromol. Sci., 25, 3063 (1975).
21. T. Kelen, F. Tüdös, and B. Turcsanyl, Polym. Bull., 2, 71 (1980).