Changes in HSP gene and protein expression in natural scrapie with brain damage

Veterinary Research

Volumn 42, Issue 1, 2011, Pages

  Serrano, Carmen ^a   Bolea, Rosa ^b   Lyahyai, Jaber ^a   Filali, Hicham ^b   Varona, Luis ^a   Marcos Carcavilla, Ane ^c   Acín, Cristina ^b   Calvo, Jorge H ^d   Serrano, Magdalena ^c   Badiola, Juan J ^b   Zaragoza, Pilar ^a   Martín Burriel, Inmaculada ^a  

^a UNIVERSIDAD DE ZARAGOZA   (Spain)

^b UNIVERSITY OF ZARAGOZA   (Spain)

^c INIA   (Spain)

^d Agrifood Institute of Aragón IA2   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; OVIS ARIES;

HEAT SHOCK PROTEIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; BRAIN; CATTLE; CATTLE DISEASE; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION; PRION; SCRAPIE; SHEEP; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BRAIN; CATTLE; CATTLE DISEASES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; POLYMERASE CHAIN REACTION; PRIONS; SCRAPIE; SHEEP;

EID: 80051999994     PISSN: 09284249     EISSN: 12979716     Source Type: Journal    
DOI: 10.1186/1297-9716-42-13     Document Type: Article

References (60)

1. Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases). Budka H, Aguzzi A, Brown P, Brucher JM, Bugiani O, Gullotta F, Haltia M, Hauw JJ, Ironside JW, Jellinger K, Kretzschmar HA, Lantos PL, Masullo C, Schlote W, Tateishi J, Weller RO, Brain Pathol 1995 5 459 466 10.1111/j.1750-3639.1995.tb00625.x 8974629
2. Incubation periods and histopathological changes in mice injected stereotaxically in different brain areas with the 87V scrapie strain. Kim YS, Carp RI, Callahan S, Wisniewski HM, Acta Neuropathol 1990 80 388 392 10.1007/BF00307692 2122631 (Pubitemid 20255762)
3. Bovine spongiform encephalopathy: diagnostic significance of vacuolar changes in selected nuclei of the medulla oblongata. Wells GA, Hancock RD, Cooley WA, Richards MS, Higgins RJ, David GP, Vet Rec 1989 125 521 524 10.1136/vr.125.21.521 2512718
4. Neuropathology of scrapie: a study of the distribution patterns of brain lesions in 222 cases of natural scrapie in sheep, 1982-1991. Wood JL, McGill IS, Done SH, Bradley R, Vet Rec 1997 140 167 174 10.1136/vr.140.7.167 9055393 (Pubitemid 127492112)
5. Lesion profiles and gliosis in the brainstem of 135 Swiss cows with bovine spongiform encephalopathy (BSE). Gubler E, Hilbe M, Ehrensperger F, Schweiz Arch Tierheilkd 2007 149 111 122 10.1024/0036-7281.149.3.111 17410969 (Pubitemid 46438374)
6. Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: from apoptosis to autophagy. Liberski PP, Sikorska B, Bratosiewicz-Wasik J, Gajdusek DC, Brown P, Int J Biochem Cell Biol 2004 36 2473 2490 10.1016/j.biocel.2004.04.016 15325586 (Pubitemid 39119760)
7. Correlation between Bax overexpression and prion deposition in medulla oblongata from natural scrapie without evidence of apoptosis. Lyahyai J, Bolea R, Serrano C, Monleon E, Moreno C, Osta R, Zaragoza P, Badiola JJ, Martin-Burriel I, Acta Neuropathol 2006 112 451 460 10.1007/s00401-006-0094-4 16804709 (Pubitemid 44469165)
8. Differential expression and protein distribution of Bax in natural scrapie. Lyahyai J, Bolea R, Serrano C, Vidal E, Pumarola M, Badiola JJ, Zaragoza P, Martin-Burriel I, Brain Res 2007 1180 111 120 10.1016/j.brainres. 2007.08.085 17949698 (Pubitemid 350018739)
9. Distinct spatial activation of intrinsic and extrinsic apoptosis pathways in natural scrapie: association with prion-related lesions. Serrano C, Lyahyai J, Bolea R, Varona L, Monleon E, Badiola JJ, Zaragoza P, Martin-Burriel I, Vet Res 2009 40 42 10.1051/vetres/2009024 19401142
10. 'Ischemic tolerance' phenomenon found in the brain. Kitagawa K, Matsumoto M, Tagaya M, Hata R, Ueda H, Niinobe M, Handa N, Fukunaga R, Kimura K, Mikoshiba K, Kamada T, Brain Res 1990 528 21 24 10.1016/0006-8993(90)90189-I 2245337 (Pubitemid 20292932)
11. Mild hypothermic intervention after graded ischemic stress in rats. Chopp M, Chen H, Dereski MO, Garcia JH, Stroke 1991 22 37 43 1987671
12. Transfection-mediated expression of human Hsp70i protects rat dorsal root ganglian neurones and glia from severe heat stress. Uney JB, Kew JN, Staley K, Tyers P, Sofroniew MV, FEBS Lett 1993 334 313 316 10.1016/0014-5793(93)80701-U 8243639 (Pubitemid 23341738)
13. Heat shock proteins hsp90 and hsp70 protect neuronal cells from thermal stress but not from programmed cell death. Mailhos C, Howard MK, Latchman DS, J Neurochem 1994 63 1787 1795 10.1046/j.1471-4159.1994.63051787.x 7931334 (Pubitemid 24326222)
14. HSP27 inhibits cytochrome c-dependent activation of procaspase-9. Garrido C, Bruey JM, Fromentin A, Hammann A, Arrigo AP, Solary E, FASEB J 1999 13 2061 2070 10544189 (Pubitemid 29517636)
15. Hsp27 negatively regulates cell death by interacting with cytochrome c. Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, Gurbuxani S, Arrigo AP, Kroemer G, Solary E, Garrido C, Nat Cell Biol 2000 2 645 652 10.1038/35023595 10980706
16. Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. Pandey P, Saleh A, Nakazawa A, Kumar S, Srinivasula SM, Kumar V, Weichselbaum R, Nalin C, Alnemri ES, Kufe D, Kharbanda S, EMBO J 2000 19 4310 4322 10.1093/emboj/19.16.4310 10944114 (Pubitemid 30623742)
17. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM, Green DR, Nat Cell Biol 2000 2 469 475 10.1038/35019501 10934466
18. Negative regulation of the Apaf-1 apoptosome by Hsp70. Saleh A, Srinivasula SM, Balkir L, Robbins PD, Alnemri ES, Nat Cell Biol 2000 2 476 483 10.1038/35019510 10934467
19. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, Mak T, Jaattela M, Penninger JM, Garrido C, Kroemer G, Nat Cell Biol 2001 3 839 843 10.1038/ncb0901-839 11533664 (Pubitemid 32842690)
20. Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor. Gurbuxani S, Schmitt E, Cande C, Parcellier A, Hammann A, Daugas E, Kouranti I, Spahr C, Pance A, Kroemer G, Garrido C, Oncogene 2003 22 6669 6678 10.1038/sj.onc.1206794 14555980 (Pubitemid 37372207)
21. The molecular chaperone concept. Ellis RJ, Semin Cell Biol 1990 1 1 9 1983265
22. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice. Kang SC, Brown DR, Whiteman M, Li R, Pan T, Perry G, Wisniewski T, Sy MS, Wong BS, J Pathol 2004 203 603 608 10.1002/path.1555 15095484 (Pubitemid 38529041)
23. HSP27 and cell survival in neurones. Latchman DS, Int J Hyperthermia 2005 21 393 402 10.1080/02656730400023664 16048837 (Pubitemid 41102939)
24. Stress and prions: lessons from the yeast model. Chernoff YO, FEBS Lett 2007 581 3695 3701 10.1016/j.febslet.2007.04.075 17509571 (Pubitemid 47081006)
25. Molecular classification of scrapie strains in mice using gene expression profiling. Booth S, Bowman C, Baumgartner R, Dolenko B, Sorensen G, Robertson C, Coulthart M, Phillipson C, Somorjai R, Biochem Biophys Res Commun 2004 325 1339 1345 10.1016/j.bbrc.2004.10.150 15555574 (Pubitemid 39535910)
26. Increased expression of heat shock protein, transferrin, and beta 2-microglobulin in astrocytes during scrapie. Diedrich JF, Carp RI, Haase AT, Microb Pathog 1993 15 1 6 10.1006/mpat.1993.1051 8412623
27. Expression of polyubiquitin and heat-shock protein 70 genes increases in the later stages of disease progression in scrapie-infected mouse brain. Kenward N, Hope J, Landon M, Mayer RJ, J Neurochem 1994 62 1870 1877 10.1046/j.1471-4159.1994.62051870.x 7512619 (Pubitemid 24121881)
28. Molecular analysis of bovine spongiform encephalopathy infection by cDNA arrays. Sawiris GP, Becker KG, Elliott EJ, Moulden R, Rohwer RG, J Gen Virol 2007 88 1356 1362 10.1099/vir.0.82387-0 17374782 (Pubitemid 46523527)
29. Abnormalities in stress proteins in prion diseases. Tatzelt J, Voellmy R, Welch WJ, Cell Mol Neurobiol 1998 18 721 729 10.1023/A:1020282205041 9876878 (Pubitemid 29012949)
30. Structural and functional analysis of the HSP90AA1 gene: distribution of polymorphisms among sheep with different responses to scrapie. Marcos-Carcavilla A, Calvo JH, Gonzalez C, Moazami-Goudarzi K, Laurent P, Bertaud M, Hayes H, Beattie AE, Serrano C, Lyahyai J, Martin-Burriel I, Serrano M, Cell Stress Chaperones 2008 13 19 29 10.1007/s12192-007-0004-2 18347938
31. Polymorphisms in the HSP90AA1 5' flanking region are associated with scrapie incubation period in sheep. Marcos-Carcavilla A, Moreno C, Serrano M, Laurent P, Cribiu EP, Andreoletti O, Ruesche J, Weisbecker JL, Calvo JH, Moazami-Goudarzi K, Cell Stress Chaperones 2010 15 343 349 10.1007/s12192-009- 0149-2 19838832
32. Detection and clinical evolution of scrapie in sheep by 3rd eyelid biopsy. Vargas F, Lujan L, Bolea R, Monleon E, Martin-Burriel I, Fernandez A, De Blas I, Badiola JJ, J Vet Intern Med 2006 20 187 193 10.1111/j.1939-1676.2006. tb02840.x 16496940 (Pubitemid 43219390)
33. Comparison of immunohistochemistry and two rapid tests for detection of abnormal prion protein in different brain regions of sheep with typical scrapie. Bolea R, Monleon E, Schiller I, Raeber AJ, Acin C, Monzon M, Martin-Burriel I, Struckmeyer T, Oesch B, Badiola JJ, J Vet Diagn Invest 2005 17 467 469 16312240 (Pubitemid 41414966)
34. Effect of scrapie on the stability of housekeeping genes. Lyahyai J, Serrano C, Ranera B, Badiola JJ, Zaragoza P, Martin-Burriel I, Anim Biotechnol 2010 21 1 13 10.1080/10495390903323851 20024782
35. A comparative study of immunohistochemical methods for detecting abnormal prion protein with monoclonal and polyclonal antibodies. Hardt M, Baron T, Groschup MH, J Comp Pathol 2000 122 43 53 10.1053/jcpa.1999.0343 10627390 (Pubitemid 30150660)
36. Immunohistochemical characterisation of classical scrapie neuropathology in sheep. Vidal E, Acin C, Foradada L, Monzon M, Marquez M, Monleon E, Pumarola M, Badiola JJ, Bolea R, J Comp Pathol 2009 141 135 146 10.1016/j.jcpa.2009.04. 002 19515381
37. Abnormal synaptic protein expression and cell death in murine scrapie. Siso S, Puig B, Varea R, Vidal E, Acin C, Prinz M, Montrasio F, Badiola J, Aguzzi A, Pumarola M, Ferrer I, Acta Neuropathol 2002 103 615 626 10.1007/s00401-001-0512-6 12012094 (Pubitemid 36067510)
38. Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones? Muchowski PJ, Neuron 2002 35 9 12 10.1016/S0896-6273(02)00761-4 12123602 (Pubitemid 34804316)
39. In vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoforms. Fernandez-Funez P, Casas-Tinto S, Zhang Y, Gomez-Velazquez M, Morales-Garza MA, Cepeda-Nieto AC, Castilla J, Soto C, Rincon-Limas DE, PLoS Genet 2009 5 1000507 10.1371/journal.pgen.1000507 19503596
40. Differential expression and regulation of hsp70 and hsp90 by phorbol esters and heat shock. Jacquier-Sarlin MR, Jornot L, Polla BS, J Biol Chem 1995 270 14094 14099 10.1074/jbc.270.23.14094 7775471
41. The 3' untranslated region of the hsp 70 genes maintains the level of steady state mRNA in Trypanosoma brucei upon heat shock. Lee MG, Nucleic Acids Res 1998 26 4025 4033 10.1093/nar/26.17.4025 9705515 (Pubitemid 28401357)
42. Heat stress regulates the human 70-kDa heat-shock gene through the 3'-untranslated region. Moseley PL, Wallen ES, McCafferty JD, Flanagan S, Kern JA, Am J Physiol 1993 264 533 537 8333545
43. Assessment of calcium-binding proteins (Parvalbumin and Calbindin D-28K) and perineuronal nets in normal and scrapie-affected adult sheep brains. Vidal E, Bolea R, Tortosa R, Costa C, Domenech A, Monleon E, Vargas A, Badiola JJ, Pumarola M, J Virol Methods 2006 136 137 146 10.1016/j.jviromet.2006.05.008 16828173 (Pubitemid 44051586)
44. Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species. Dedmon MM, Christodoulou J, Wilson MR, Dobson CM, J Biol Chem 2005 280 14733 14740 10.1074/jbc.M413024200 15671022 (Pubitemid 40562821)
45. Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils. Muchowski PJ, Schaffar G, Sittler A, Wanker EE, Hayer-Hartl MK, Hartl FU, Proc Natl Acad Sci USA 2000 97 7841 7846 10.1073/pnas.140202897 10859365 (Pubitemid 30460735)
46. Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro. Evans CG, Wisen S, Gestwicki JE, J Biol Chem 2006 281 33182 33191 10.1074/jbc.M606192200 16973602 (Pubitemid 46036699)
47. Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3. Wen FC, Li YH, Tsai HF, Lin CH, Li C, Liu CS, Lii CK, Nukina N, Hsieh M, FEBS Lett 2003 546 307 314 10.1016/S0014-5793(03)00605-7 12832059 (Pubitemid 36782430)
48. Decreased expression of Hsp27 and Hsp70 in transformed lymphoblastoid cells from patients with spinocerebellar ataxia type 7. Tsai HF, Lin SJ, Li C, Hsieh M, Biochem Biophys Res Commun 2005 334 1279 1286 10.1016/j.bbrc.2005.06. 207 16039988 (Pubitemid 41074712)
49. Brain cytokine network and novel characteristics of microglia. Sawada M, Nihon Shinkei Seishin Yakurigaku Zasshi 1999 19 151 154 in Japanese 10681160 (Pubitemid 30013150)
50. Fas and Fas ligand expression in Alzheimer's disease. Ferrer I, Puig B, Krupinsk J, Carmona M, Blanco R, Acta Neuropathol 2001 102 121 131 11563626 (Pubitemid 32771659)
51. Increased cerebrospinal fluid fas (Apo-1) levels in Alzheimer's disease. Relationship with IL-6 concentrations. Martinez M, Fernandez-Vivancos E, Frank A, De la Fuente M, Hernanz A, Brain Res 2000 869 216 219 10.1016/S0006-8993(00) 02363-5 10865077 (Pubitemid 30345793)
52. Stress response in the central nervous system of a transgenic mouse model of bovine spongiform encephalopathy. Tortosa R, Vidal E, Costa C, Alamillo E, Torres JM, Ferrer I, Pumarola M, Vet J 2008 178 126 129 10.1016/j.tvjl.2007.06. 002 17692544
53. Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury. Giffard RG, Xu L, Zhao H, Carrico W, Ouyang Y, Qiao Y, Sapolsky R, Steinberg G, Hu B, Yenari MA, J Exp Biol 2004 207 3213 3220 10.1242/jeb.01034 15299042 (Pubitemid 39275295)
54. Regulation of apoptosis-associated proteins in cell death following transient focal ischemia in rat pups. Renolleau S, Benjelloun N, Ben-Ari Y, Charriaut-Marlangue C, Apoptosis 1997 2 368 376 10.1023/A:1026453623753 14646533 (Pubitemid 127504720)
55. Heat shock protein-90-induced microglial clearance of exogenous amyloid-beta1-42 in rat hippocampus in vivo. Takata K, Kitamura Y, Tsuchiya D, Kawasaki T, Taniguchi T, Shimohama S, Neurosci Lett 2003 344 87 90 10.1016/S0304-3940(03)00447-6 12782334 (Pubitemid 36628013)
56. Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. Kakimura J, Kitamura Y, Takata K, Umeki M, Suzuki S, Shibagaki K, Taniguchi T, Nomura Y, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S, FASEB J 2002 16 601 603 11919167 (Pubitemid 44793415)
57. Heat shock protein 70 expression in epilepsy suggests stress rather than protection. Yang T, Hsu C, Liao W, Chuang JS, Acta Neuropathol 2008 115 219 230 10.1007/s00401-007-0297-3 17929041
58. Prominent stress response of Purkinje cells in Creutzfeldt-Jakob disease. Kovacs GG, Kurucz I, Budka H, Adori C, Muller F, Acs P, Kloppel S, Schatzl HM, Mayer RJ, Laszlo L, Neurobiol Dis 2001 8 881 889 10.1006/nbdi.2001.0418 11592855 (Pubitemid 33055602)
59. Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene. Sakaguchi S, Katamine S, Nishida N, Moriuchi R, Shigematsu K, Sugimoto T, Nakatani A, Kataoka Y, Houtani T, Shirabe S, Okada H, Hasegawa S, Miyamoto T, Noda T, Nature 1996 380 528 531 10.1038/380528a0 8606772 (Pubitemid 26110641)
60. Doppel-induced cerebellar degeneration in transgenic mice. Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P, Proc Natl Acad Sci USA 2001 98 15288 15293 10.1073/pnas.251550798 11734625 (Pubitemid 34014007)