-
1
-
-
0028882673
-
Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E
-
Hancock W.W., Polanski M., Zhang J., Blogg N., Weiner H.L. Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E. Am J Pathol 1995;147:1193-1199
-
(1995)
Am J Pathol
, vol.147
, pp. 1193-1199
-
-
Hancock, W.W.1
Polanski, M.2
Zhang, J.3
Blogg, N.4
Weiner, H.L.5
-
3
-
-
0030754787
-
Metabolically inactive insulin analog prevents type I diabetes in prediabetic NOD mice
-
Karounos D.G., Bryson J.S., Cohen D.A. Metabolically inactive insulin analog prevents type I diabetes in prediabetic NOD mice. J Clin Invest 1997;100:1344-1348 (Pubitemid 27425758)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.6
, pp. 1344-1348
-
-
Karounos, D.G.1
Bryson, J.S.2
Cohen, D.A.3
-
4
-
-
0030050676
-
Immunological and metabolic effects of prophylactic insulin therapy in the NOD-scid/scid adoptive transfer model of IDDM
-
Bowman M.A., Campbell L., Darrow B.L., Ellis T.M., Suresh A., Atkinson M.A. Immunological and metabolic effects of prophylactic insulin therapy in the NODscid/scid adoptive transfer model of IDDM. Diabetes 1996;45:205-208 (Pubitemid 26048674)
-
(1996)
Diabetes
, vol.45
, Issue.2
, pp. 205-208
-
-
Bowman, M.A.1
Campbell, L.2
Darrow, B.L.3
Ellis, T.M.4
Suresh, A.5
Atkinson, M.A.6
-
5
-
-
0027480065
-
Insulin prophylaxis in individuals at high risk of type I diabetes
-
DOI 10.1016/0140-6736(93)91215-8
-
Keller R.J., Eisenbarth G.S., Jackson R.A. Insulin prophylaxis in individuals at high risk of type I diabetes. Lancet 1993;341:927-928 (Pubitemid 23109113)
-
(1993)
Lancet
, vol.341
, Issue.8850
, pp. 927-928
-
-
Keller, R.J.1
Eisenbarth, G.S.2
Jackson, R.A.3
-
6
-
-
0037198427
-
Effects of insulin in relatives of patients with type 1 diabetes mellitus
-
Diabetes Prevention Trial-Type 1 Diabetes Study Group
-
Diabetes Prevention Trial-Type 1 Diabetes Study Group. Effects of insulin in relatives of patients with type 1 diabetes mellitus. N Engl J Med 2002;346:1685-1691
-
(2002)
N Engl J Med
, vol.346
, pp. 1685-1691
-
-
-
7
-
-
18144391496
-
Effects of oral insulin in relatives of patients with type 1 diabetes: The diabetes prevention trial-type 1
-
DOI 10.2337/diacare.28.5.1068
-
Skyler J.S., Krischer J.P., Wolfsdorf J., et al. Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial - Type 1. Diabetes Care 2005;28:1068-1076 (Pubitemid 40616615)
-
(2005)
Diabetes Care
, vol.28
, Issue.5
, pp. 1068-1076
-
-
Skyler, J.S.1
-
8
-
-
55749104546
-
Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: A double-blind, randomised controlled trial
-
Näntö-Salonen K., Kupila A., Simell S., et al. Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: A double-blind, randomised controlled trial. Lancet 2008;372:1746-1755
-
(2008)
Lancet
, vol.372
, pp. 1746-1755
-
-
Näntö-Salonen, K.1
Kupila, A.2
Simell, S.3
-
9
-
-
4344690190
-
Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes
-
DOI 10.1172/JCI200421307
-
Achenbach P., Koczwara K., Knopff A., Naserke H., Ziegler A.G., Bonifacio E. Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes. J Clin Invest 2004;114:589-597 (Pubitemid 39572109)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.4
, pp. 589-597
-
-
Achenbach, P.1
Koczwara, K.2
Knopff, A.3
Naserke, H.4
Ziegler, A.-G.5
Bonifacio, E.6
-
10
-
-
24944540702
-
In insulin-autoantibody-positive children from the general population, antibody affinity identifies those at high and low risk
-
DOI 10.1007/s00125-005-1864-6
-
Schlosser M., Koczwara K., Kenk H., et al. In insulin-autoantibody- positive children from the general population, antibody affinity identifies those at high and low risk. Diabetologia 2005;48:1830-1832 (Pubitemid 41317837)
-
(2005)
Diabetologia
, vol.48
, Issue.9
, pp. 1830-1832
-
-
Schlosser, M.1
Koczwara, K.2
Kenk, H.3
Strebelow, M.4
Rjasanowski, I.5
Wassmuth, R.6
Achenbach, P.7
Ziegler, A.-G.8
Bonifacio, E.9
-
11
-
-
70350586604
-
Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility
-
Siljander H., Härkönen T., Hermann R., et al. Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility. Diabetes Metab Res Rev 2009;25:615-622
-
(2009)
Diabetes Metab Res Rev
, vol.25
, pp. 615-622
-
-
Siljander, H.1
Härkönen, T.2
Hermann, R.3
-
12
-
-
1642555898
-
Insulin Autoantibody Isotypes during the Prediabetic Process in Young Children with Increased Genetic Risk of Type 1 Diabetes
-
DOI 10.1203/01.PDR.0000100905.41131.3F
-
Hoppu S., Ronkainen M.S., Kimpimäki T., et al. Insulin autoantibody isotypes during the prediabetic process in young children with increased genetic risk of type 1 diabetes. Pediatr Res 2004;55:236-242 (Pubitemid 38121001)
-
(2004)
Pediatric Research
, vol.55
, Issue.2
, pp. 236-242
-
-
Hoppu, S.1
Ronkainen, M.S.2
Kimpimaki, T.3
Simell, S.4
Korhonen, S.5
Ilonen, J.6
Simell, O.7
Knip, M.8
-
13
-
-
17944381519
-
The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: The Finnish Type 1 Diabetes Prediction and Prevention Study
-
Kimpimäki T., Kupila A., Hämäläinen A.M., et al. The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: The Finnish Type 1 Diabetes Prediction and Prevention Study. J Clin Endocrinol Metab 2001;86:4782-4788
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4782-4788
-
-
Kimpimäki, T.1
Kupila, A.2
Hämäläinen, A.M.3
-
14
-
-
0029799524
-
Rapid HLA-DQB1 genotyping for four alleles in the assessment of risk for IDDM in the Finnish population
-
Ilonen J., Reijonen H., Herva E., et al. Rapid HLA-DQB1 genotyping for four alleles in the assessment of risk for IDDM in the Finnish population. The Childhood Diabetes in Finland (DiMe) Study Group. Diabetes Care 1996;19:795-800 (Pubitemid 26286981)
-
(1996)
Diabetes Care
, vol.19
, Issue.8
, pp. 795-800
-
-
Ilonen, J.1
Reijonen, H.2
Herva, E.3
Sjoroos, M.4
Iitia, A.5
Lovgren, T.6
Veijola, R.7
Knip, M.8
Akerblom, H.K.9
-
15
-
-
0033401173
-
Population-based genetic screening for the estimation of Type 1 diabetes mellitus risk in Finland: Selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci
-
DOI 10.1046/j.1464-5491.1999.00186.x
-
Nejentsev S., Sjöroos M., Soukka T., et al. Population-based genetic screening for the estimation of type 1 diabetes mellitus risk in Finland: Selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci. Diabet Med 1999;16:985-992 (Pubitemid 30051424)
-
(1999)
Diabetic Medicine
, vol.16
, Issue.12
, pp. 985-992
-
-
Nejentsev, S.1
Sjoroos, M.2
Soukka, T.3
Knip, M.4
Simell, O.5
Lovgren, T.6
Ilonen, J.7
-
16
-
-
0029042730
-
Triple-label hybridization assay for type-1 diabetes-related HLA alleles
-
Sjöroos M., Iitiä A., Ilonen J., Reijonen H., Lövgren T. Triple-label hybridization assay for type-1 diabetes-related HLA alleles. Biotechniques 1995;18:870-877
-
(1995)
Biotechniques
, vol.18
, pp. 870-877
-
-
Sjöroos, M.1
Iitiä, A.2
Ilonen, J.3
Reijonen, H.4
Lövgren, T.5
-
17
-
-
0016261369
-
Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies
-
Bottazzo G.F., Florin-Christensen A., Doniach D. Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet 1974;2:1279-1283
-
(1974)
Lancet
, vol.2
, pp. 1279-1283
-
-
Bottazzo, G.F.1
Florin-Christensen, A.2
Doniach, D.3
-
18
-
-
0030798560
-
A novel micro-assay for insulin autoantibodies
-
DOI 10.1006/jaut.1997.0154
-
Williams A.J., Bingley P.J., Bonifacio E., Palmer J.P., Gale E.A. A novel micro-assay for insulin autoantibodies. J Autoimmun 1997;10:473-478 (Pubitemid 27433643)
-
(1997)
Journal of Autoimmunity
, vol.10
, Issue.5
, pp. 473-478
-
-
Williams, A.J.K.1
Bingley, P.J.2
Bonifacio, E.3
Palmer, J.P.4
Gale, E.A.M.5
-
19
-
-
6844252890
-
IA-2 antibodies - A sensitive marker of IDDM with clinical onset in childhood and adolescence
-
DOI 10.1007/s001250050925
-
Savola K., Bonifacio E., Sabbah E., et al. IA-2 antibodies - a sensitive marker of IDDM with clinical onset in childhood and adolescence. Childhood Diabetes in Finland Study Group. Diabetologia 1998;41:424-429 (Pubitemid 28157413)
-
(1998)
Diabetologia
, vol.41
, Issue.4
, pp. 424-429
-
-
Savola, K.1
Bonifacio, E.2
Sabbah, E.3
Kulmala, P.4
Vahasalo, P.5
Karjalainen, J.6
Tuomilehto-Wolf, E.7
Merilainen, J.8
Akerblom, H.K.9
Knip, M.10
-
20
-
-
0031739110
-
Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children
-
DOI 10.1007/s001250051067
-
Savola K., Sabbah E., Kulmala P., Vähäsalo P., Ilonen J., Knip M. Autoantibodies associated with type I diabetes mellitus persist after diagnosis in children. Diabetologia 1998;41:1293-1297 (Pubitemid 28488755)
-
(1998)
Diabetologia
, vol.41
, Issue.11
, pp. 1293-1297
-
-
Savola, K.1
Sabbah, E.2
Kulmala, P.3
Vahasalo, P.4
Ilonen, J.5
Knip, M.6
-
21
-
-
4644230843
-
Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes
-
DOI 10.2337/diacare.27.10.2348
-
Harrison L.C., Honeyman M.C., Steele C.E., et al. Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes. Diabetes Care 2004;27:2348-2355 (Pubitemid 39281384)
-
(2004)
Diabetes Care
, vol.27
, Issue.10
, pp. 2348-2355
-
-
Harrison, L.C.1
Honeyman, M.C.2
Steele, C.E.3
Stone, N.L.4
Sarugeri, E.5
Bonifacio, E.6
Couper, J.J.7
Colman, P.G.8
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