Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression

Molecular Immunology

Volumn 48, Issue 15-16, 2011, Pages 1800-1808

  Shweash, Muhannad ^a   Adrienne McGachy, H ^a   Schroeder, Juliane ^a   Neamatallah, Thikryat ^a   Bryant, Clare E ^b   Millington, Owain ^a   Mottram, Jeremy C ^c   Alexander, James ^a   Plevin, Robin ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Arginase 1; IL 12; Leishmania mexicana; MAP kinase; Promastigotes; TLR 4

Indexed keywords

ARGINASE; ARGINASE 1; ARGININE DERIVATIVE; CYCLOOXYGENASE 2; CYSTEINE; CYSTEINE PEPTIDASE B; INOSINATE DEHYDROGENASE; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; ENZYME ACTIVITY; ENZYME INHIBITION; LEISHMANIA MEXICANA; MACROPHAGE; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN EXPRESSION;

ANIMALS; ARGINASE; BLOTTING, WESTERN; CYCLOOXYGENASE 2; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INTERLEUKIN-12; LEISHMANIA MEXICANA; LEISHMANIASIS; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE TYPE II; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

LEISHMANIA MEXICANA;

EID: 80051943703     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.05.013     Document Type: Article

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