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Volumn 117, Issue 3, 1999, Pages 469-475

Interferon-gamma (IFN-γ) and prostaglandin E2 (PGE2) regulate differently IL-12 production in human intestinal lamina propria mononuclear cells (LPMC)

Author keywords

IL 12; Interferon gamma; Intestinal inflammation; Lipopolysaccharide; Prostaglandin E2

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INDOMETACIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2;

EID: 0032800437     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00991.x     Document Type: Article
Times cited : (27)

References (39)
  • 1
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • 1 Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995; 13:251-76.
    • (1995) Annu Rev Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 2
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
    • 2 Trinchieri G. Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 1994; 84:4006-27.
    • (1994) Blood , vol.84 , pp. 4006-4027
    • Trinchieri, G.1
  • 3
    • 0029047009 scopus 로고
    • Biology of disease. Interleukin-12. Biology activity, therapeutic utility, and role in disease
    • 3 Hendrzak JA, Brunda MJ. Biology of disease. Interleukin-12. Biology activity, therapeutic utility, and role in disease. Lab Invest 1995; 72:619-37.
    • (1995) Lab Invest , vol.72 , pp. 619-637
    • Hendrzak, J.A.1    Brunda, M.J.2
  • 4
    • 0030064148 scopus 로고    scopus 로고
    • The interleukin 12 p40 gene promoter is primed by interferon-γ in monocytic cells
    • 4 Ma X, Chow JM, Cri G et al. The interleukin 12 p40 gene promoter is primed by interferon-γ in monocytic cells. J Exp Med 1996; 183:147-57.
    • (1996) J Exp Med , vol.183 , pp. 147-157
    • Ma, X.1    Chow, J.M.2    Cri, G.3
  • 5
    • 0028943066 scopus 로고
    • Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumour necrosis factor α
    • 5 Flesch IEA, Hess JH, Huang S et al. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumour necrosis factor α. J Exp Med 1995; 181:1615-21.
    • (1995) J Exp Med , vol.181 , pp. 1615-1621
    • Flesch, I.E.A.1    Hess, J.H.2    Huang, S.3
  • 6
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • 6 Monteleone G, Biancone L, Marasco R et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997; 112:1169-78.
    • (1997) Gastroenterology , vol.112 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3
  • 7
    • 0031057872 scopus 로고    scopus 로고
    • Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
    • 7 Parronchi P, Romagnani P, Annunziato F et al. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol 1997; 150:823-32.
    • (1997) Am J Pathol , vol.150 , pp. 823-832
    • Parronchi, P.1    Romagnani, P.2    Annunziato, F.3
  • 8
    • 0009614308 scopus 로고
    • The interferon system in inflammatory bowel disease
    • Fiocchi C, eds. Austin, Texas: R G Landes Co.
    • 8 Pallone F, Fais S, Boirivant M. The Interferon system in inflammatory bowel disease. In: Fiocchi C, eds. Cytokines in inflammatory bowel disease. Austin, Texas: R G Landes Co., 1995:57-67.
    • (1995) Cytokines in Inflammatory Bowel Disease , pp. 57-67
    • Pallone, F.1    Fais, S.2    Boirivant, M.3
  • 9
    • 0025804331 scopus 로고
    • Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to Interferon gamma inducers
    • 9 Fais S, Capobianchi MR, Pallone F et al. Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to Interferon gamma inducers. Gut 1991; 32:403-7.
    • (1991) Gut , vol.32 , pp. 403-407
    • Fais, S.1    Capobianchi, M.R.2    Pallone, F.3
  • 10
    • 0028576989 scopus 로고
    • Interferon expression in Crohn's disease patients: Increased interferon-gamma and -alpha mRNA in the intestinal lamina propria mononuclear cells
    • 10 Fais S, Capobianchi MR, Silvestri M et al. Interferon expression in Crohn's disease patients: increased interferon-gamma and -alpha mRNA in the intestinal lamina propria mononuclear cells. J Interferon Res 1994; 14:235-8.
    • (1994) J Interferon Res , vol.14 , pp. 235-238
    • Fais, S.1    Capobianchi, M.R.2    Silvestri, M.3
  • 11
    • 0030209985 scopus 로고    scopus 로고
    • Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
    • 11 Fuss IJ, Neurath M, Boirivant M et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 1996; 157:1261-70.
    • (1996) J Immunol , vol.157 , pp. 1261-1270
    • Fuss, I.J.1    Neurath, M.2    Boirivant, M.3
  • 12
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • 12 Neurath MF, Fuss I, Kelsall BL et al. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 1995; 182:1281-90.
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3
  • 13
    • 0031743056 scopus 로고    scopus 로고
    • Response of human intestinal lamina propría T lymphocytes to interleukin 12: Additive effects of interleukin 15 and 7
    • 13 Monteleone G, Parrello T, Luzza F et al. Response of human intestinal lamina propría T lymphocytes to interleukin 12: additive effects of interleukin 15 and 7. Gut 1998; 43:620-8.
    • (1998) Gut , vol.43 , pp. 620-628
    • Monteleone, G.1    Parrello, T.2    Luzza, F.3
  • 14
    • 0027521572 scopus 로고
    • Interleukin-10 deficient mice develop chronic enterocolitis
    • 14 Kuhn R, Lohler J, Rennick D et al. Interleukin-10 deficient mice develop chronic enterocolitis. Cell 1993; 75:263-74.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3
  • 15
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • 15 Sellon RK, Tonkonogy S, Schultz M et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998; 66:5224-31.
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3
  • 16
    • 0029787626 scopus 로고    scopus 로고
    • Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo
    • 16 Portanova JP, Zhang Y, Anderson GD et al. Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo. J Exp Med 1996; 184:883-91.
    • (1996) J Exp Med , vol.184 , pp. 883-891
    • Portanova, J.P.1    Zhang, Y.2    Anderson, G.D.3
  • 17
    • 0015890986 scopus 로고
    • Prostaglandins as potentiators of increased vascular permeability in inflammation
    • 17 Williams TJ, Morley J. Prostaglandins as potentiators of increased vascular permeability in inflammation. Nature 1973; 246:215-7.
    • (1973) Nature , vol.246 , pp. 215-217
    • Williams, T.J.1    Morley, J.2
  • 18
    • 0025744448 scopus 로고
    • A new view of prostaglandin E regulation of the immune response
    • 18 Phipps RP, Stein SH, Roper RL. A new view of prostaglandin E regulation of the immune response. Immunol Today 1991, 12:349-52.
    • (1991) Immunol Today , vol.12 , pp. 349-352
    • Phipps, R.P.1    Stein, S.H.2    Roper, R.L.3
  • 19
    • 0028936406 scopus 로고
    • Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production
    • 19 van der Pouw Kraan TCTM, Boeije LCM, Smcenk RJT et al. Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. J Exp Med 1995; 181:775-9.
    • (1995) J Exp Med , vol.181 , pp. 775-779
    • Van Der Pouw Kraan, T.C.T.M.1    Boeije, L.C.M.2    Smcenk, R.J.T.3
  • 20
    • 0028109394 scopus 로고
    • Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages hy prostaglandin E2
    • 20 Strassmann G, Koota VP, Finkelman F et al. Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages hy prostaglandin E2. J Exp Med 1994; 180:2365-70.
    • (1994) J Exp Med , vol.180 , pp. 2365-2370
    • Strassmann, G.1    Koota, V.P.2    Finkelman, F.3
  • 21
    • 0023109767 scopus 로고
    • Interference with tolerance induction in vivo by inhibitors of prostaglandin synthesis
    • 21 Scheuer WV, Hobbs MV, Weigle WO. Interference with tolerance induction in vivo by inhibitors of prostaglandin synthesis. Cell Immunol 1987; 104:409-16.
    • (1987) Cell Immunol , vol.104 , pp. 409-416
    • Scheuer, W.V.1    Hobbs, M.V.2    Weigle, W.O.3
  • 22
    • 0030995158 scopus 로고    scopus 로고
    • Cytokine profiles differ in newly recruited and resident subsets of mucosal macrophages from inflammatory bowel disease
    • 22 Rugtveit J, Nilsen EM, Bakka A et al. Cytokine profiles differ in newly recruited and resident subsets of mucosal macrophages from inflammatory bowel disease. Gastroenterology 1997; 112:1493-505.
    • (1997) Gastroenterology , vol.112 , pp. 1493-1505
    • Rugtveit, J.1    Nilsen, E.M.2    Bakka, A.3
  • 23
    • 0029112298 scopus 로고
    • Intestinal epithelial cells down-regulate macrophage tumor necrosis factor-alpha secretion: A mechanism for immune homeostasis in the gut-associated lymphoid tissue
    • 23 Nathens AB, Rotstein OD, Dackiw APB et al. Intestinal epithelial cells down-regulate macrophage tumor necrosis factor-alpha secretion: a mechanism for immune homeostasis in the gut-associated lymphoid tissue. Surgery 1995; 118:343-51.
    • (1995) Surgery , vol.118 , pp. 343-351
    • Nathens, A.B.1    Rotstein, O.D.2    Dackiw, A.P.B.3
  • 24
    • 0028848472 scopus 로고
    • Role of interferon-gamma in immune cell regulation
    • 24 Young HA, Hardy KJ. Role of interferon-gamma in immune cell regulation. J Leuk Biol 1995; 58:373-81.
    • (1995) J Leuk Biol , vol.58 , pp. 373-381
    • Young, H.A.1    Hardy, K.J.2
  • 25
    • 0029040855 scopus 로고
    • Regulation of interleukin-12 expression in human monocytes: Selective priming by interferon-γ of lipopolysaccharide-inducible p35 and p40 genes
    • 25 Hayes MP, Wang J, Norcross MA. Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-γ of lipopolysaccharide-inducible p35 and p40 genes. Blood 1995; 86:646-50.
    • (1995) Blood , vol.86 , pp. 646-650
    • Hayes, M.P.1    Wang, J.2    Norcross, M.A.3
  • 26
    • 0030917203 scopus 로고    scopus 로고
    • Monocyte deactivation in septic patients: Restoration hy IFN-γ treatment
    • 26 Docke W-D, Randow F, Syrbe U et al. Monocyte deactivation in septic patients: restoration hy IFN-γ treatment. Nature Med 1997; 3:678-81.
    • (1997) Nature Med , vol.3 , pp. 678-681
    • Docke, W.-D.1    Randow, F.2    Syrbe, U.3
  • 28
    • 0028911482 scopus 로고
    • Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: Priming for IL-12 and tumor necrosis factor a production
    • 28 D'Andrea A, Ma X, Aste-Amezaga M et al. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor a production. J Exp Med 1995; 181:537-46.
    • (1995) J Exp Med , vol.181 , pp. 537-546
    • D'Andrea, A.1    Ma, X.2    Aste-Amezaga, M.3
  • 29
    • 0030881353 scopus 로고    scopus 로고
    • Interferon-gamma (IFN-γ) regulates production of IL-10 and IL-12 in human herpesvirus-6 (HHV-6)-infected monocyte/macrophage lineage
    • 29 Li C, Goodrich JM, Yang X. Interferon-gamma (IFN-γ) regulates production of IL-10 and IL-12 in human herpesvirus-6 (HHV-6)-infected monocyte/macrophage lineage. Clin Exp Immunol 1997; 109:421-5.
    • (1997) Clin Exp Immunol , vol.109 , pp. 421-425
    • Li, C.1    Goodrich, J.M.2    Yang, X.3
  • 30
    • 0025764159 scopus 로고
    • Preexposure of macrophages to low doses of lipopolysaccharide inhibits the expression of tumor necrosis factor-α mRNA but not of IL-1β mRNA
    • 30 Takasuka N, Tokunaga T, Akagawa KS. Preexposure of macrophages to low doses of lipopolysaccharide inhibits the expression of tumor necrosis factor-α mRNA but not of IL-1β mRNA. J Immunol 1991; 146:3824-30.
    • (1991) J Immunol , vol.146 , pp. 3824-3830
    • Takasuka, N.1    Tokunaga, T.2    Akagawa, K.S.3
  • 31
    • 0024553788 scopus 로고
    • Interferon-γ directly affects barrier function of cultured intestinal epithelial monolayers
    • 31 Madara JL, Stafford J. Interferon-γ directly affects barrier function of cultured intestinal epithelial monolayers. J Clin Invest 1989; 83:724-7.
    • (1989) J Clin Invest , vol.83 , pp. 724-727
    • Madara, J.L.1    Stafford, J.2
  • 32
    • 0027245531 scopus 로고
    • IFN-γ modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding
    • 32 Adams RB, Planchon SM, Roche JK. IFN-γ modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding. J Immunol 1993; 150:2356-63.
    • (1993) J Immunol , vol.150 , pp. 2356-2363
    • Adams, R.B.1    Planchon, S.M.2    Roche, J.K.3
  • 33
    • 0031080948 scopus 로고    scopus 로고
    • Reciprocal IFN-γ and TGF-β responses regulate the occurrence of mucosal inflammation
    • 33 Strober W, Kelsall B, Fuss I et al. Reciprocal IFN-γ and TGF-β responses regulate the occurrence of mucosal inflammation. Immunol Today 1997; 18:61-64.
    • (1997) Immunol Today , vol.18 , pp. 61-64
    • Strober, W.1    Kelsall, B.2    Fuss, I.3
  • 34
    • 0029993786 scopus 로고    scopus 로고
    • Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12
    • 34 Duchmann R, Schmitt E, Knolle P et al. Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12. Eur J Immunol 1996; 26:934-8.
    • (1996) Eur J Immunol , vol.26 , pp. 934-938
    • Duchmann, R.1    Schmitt, E.2    Knolle, P.3
  • 35
    • 0025924175 scopus 로고
    • Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines
    • 35 Betz M, Fox BS. Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J Immunol 1991; 146:108-13.
    • (1991) J Immunol , vol.146 , pp. 108-113
    • Betz, M.1    Fox, B.S.2
  • 36
    • 0027336504 scopus 로고
    • Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes
    • 36 Snijdewint FGM, Kalinski P, Wierenga EA et al. Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 1993; 150:5321-9.
    • (1993) J Immunol , vol.150 , pp. 5321-5329
    • Snijdewint, F.G.M.1    Kalinski, P.2    Wierenga, E.A.3
  • 37
    • 0018868463 scopus 로고
    • Ulcerative enterocolitis in dogs induced by drugs
    • 37 Stewart TH, Hetenyi C, Rowsell H et al. Ulcerative enterocolitis in dogs induced by drugs. J Pathol 1980; 131:363-78.
    • (1980) J Pathol , vol.131 , pp. 363-378
    • Stewart, T.H.1    Hetenyi, C.2    Rowsell, H.3
  • 38
    • 77953023142 scopus 로고
    • Indomethacin induced chronic small intestinal ulceration in the rat
    • 38 Bjarnason I, Smethurst P, Levi AJ et al. Indomethacin induced chronic small intestinal ulceration in the rat. Gastroenterology 1988; 94:1937.
    • (1988) Gastroenterology , vol.94 , pp. 1937
    • Bjarnason, I.1    Smethurst, P.2    Levi, A.J.3
  • 39
    • 0032080187 scopus 로고    scopus 로고
    • Differential deactivation of human dendritic cells by endotoxin desensitisation: Role of tumor necrosis factor-α and prostaglandin E2
    • 39 Rieser C, Papesh C, Herold M et al. Differential deactivation of human dendritic cells by endotoxin desensitisation: role of tumor necrosis factor-α and prostaglandin E2. Blood 1998; 91:3112-7.
    • (1998) Blood , vol.91 , pp. 3112-3117
    • Rieser, C.1    Papesh, C.2    Herold, M.3


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