Glycogen synthase kinase-3β (GSK3β) negatively regulates PTTG1/human securin protein stability, and GSK3β inactivation correlates with securin accumulation in breast tumors

Journal of Biological Chemistry

Volumn 286, Issue 34, 2011, Pages 30047-30056

  Mora Santos, Mar ^a   Limón Mortés, M Cristina ^a   Giráldez, Servando ^a   Herrero Ruiz, Joaquín ^a   Sáez, Carmen ^b   Japón, Miguel Á ^b   Tortolero, Maria ^a   Romero, Francisco ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE-PROMOTING COMPLEXES; BREAST CANCER; BREAST TUMOR; CHROMOSOME SEGREGATION; CYCLOSOME; GLYCOGEN SYNTHASE KINASE-3; HUMAN CANCER; PROTEIN STABILITY; SECURIN; STRONG CORRELATION; TUMOR PROGRESSIONS; UBIQUITIN LIGASES;

DISEASES; PHOSPHORYLATION; TUMORS;

ENZYMES;

GLYCOGEN SYNTHASE KINASE 3BETA; SECURIN; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; BREAST ADENOCARCINOMA; CANCER TISSUE; CELL CYCLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME INACTIVATION; HUMAN; HUMAN TISSUE; MITOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REGULATORY MECHANISM;

ANIMALS; BREAST NEOPLASMS; CERCOPITHECUS AETHIOPS; COS CELLS; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HELA CELLS; HUMANS; MITOSIS; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN STABILITY; SKP CULLIN F-BOX PROTEIN LIGASES;

EID: 80051943117     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.232330     Document Type: Article

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