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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 18, 2011, Pages 5642-5645

2-Phenyl and 2-heterocyclic-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridines as inhibitors of TGF-β1 and activin A signalling

(7) Ciayadi, Rudy a Potdar, Mahesh a Walton, Kelly L b Harrison, Craig A b Kelso, Geoffrey F a Harris, Simon J a Hearn, Milton T W a

a MONASH UNIVERSITY (Australia)

b MONASH MEDICAL CENTRE (Australia)

Author keywords

Activin A; ATP competitive ALK4 ALK5 inhibitors; Low molecular weight inhibitors; Structure activity relationships; Transforming growth factor

Indexed keywords

2 ARYL 4 [3 (PYRIDIN 2 YL) 1H PYRAZOL 4 YL]PYRIDINE DERIVATIVE; ACTIVIN A; PYRIDINE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ACTIVINS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HEK293 CELLS; HETEROCYCLIC COMPOUNDS; HUMANS; MOLECULAR STRUCTURE; PYRIDINES; SIGNAL TRANSDUCTION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFORMING GROWTH FACTOR BETA1;

EID: 80051943106 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2010.12.120 Document Type: Article

Times cited : (12)

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