FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor β signals

Molecular and Cellular Biology

Volumn 19, Issue 1, 1999, Pages 424-430

  Liu, Bo ^a   Dou, Chang Lin ^a   Prabhu, Leena ^a   Lai, Eseng ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

AMINO ACID SEQUENCE; ARTICLE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; XENOPUS;

XENOPUS;

EID: 0032909167     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.1.424     Document Type: Article

References (26)

1. Ang, S., and J. Rossant. 1994. HNF-3beta is essential for node and notochord formation in mouse development. Cell 78:561-574.
2. Brissette, J., J. Li, J. Kamimura, D. Lee, and G. Dotto. 1996. The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation. Genes Dev. 10:2212-2221.
3. Bristow, J., M. K. Tee, S. E. Gitelman, S. H. Mellon, and W. L. Miller. 1993. Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B. J. Cell Biol. 122:265-278.
4. Chen, X., M. Rubock, and M. Whitman. 1996. A transcriptional partner for MAD proteins in TGF-β signalling. Nature 383:691-696.
5. Chen, X. E. Weisberg, V. Fridmacher, M. Watanabe, G. Naco, and M. Whitman. 1997. Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature 389:85-89.
6. Clark, K., E. Halay, E. Lai, and S. Burley. 1993 Cocrystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364:412-420.
7. Dou, C., X. Ye, C. Stewart, E. Lai, and S. Li. 1997. TWH regulates the development of subsets of spinal cord neurons. Neuron 18:539-551.
8. Frohman, M. A., M. K. Dush, and G. R. Martin. 1988. Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA 85:8998-9002.
9. Hanlon, D. W., Z. Yang, and L. S. B. Goldstein. 1997. Characterization of KIFC2, a neuronal kinesin superfamily member in mouse. Neuron 18:439-451.
10. Hatini, V., S. Huh, D. Herzlinger, V. Soares, and E. Lai. 1996. Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of winged-helix transcription factor. BF-2. Genes Dev. 10:1467-1478.
11. Huang, H.-C., L. C. Murtaugh, P. D. Vize, and M. Whitman. 1995. Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo. EMBO J. 14:5965-5973.
12. Kaufman, E., and W. Knochel. 1996. Five years on the wings of fork head. Mech. Dev. 57:3-20.
13. Kume, T., K.-Y. Deng, V. Winfrey, D. B. Gould, M. A. Walter, and B. L. M. Hogan. 1998. The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus. Cell 93:985-996.
14. Labbe, E., C. Silvestri, P. Hoodless, J. Wrana, and L. Attisano. 1998. Smad2 and Smad3 positively and negatively regulate TGFβ-dependent transcription through the forkhead DNA-binding protein FAST2. Mol. Cell 2:109-120.
15. Labosky, P., G. Winnier, T. Jetton, L. Hargett, A. Ryan, M. Rosenfeld, A. Parlow, and B. Hogan. 1997. The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. Development 124:1263-1274.
16. Lai, E., K. Clark, S. Burley, and J. Darnell. 1993. Hepatocyte nuclear factor-3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function. Proc. Natl. Acad. Sci. USA 90:10421-10423.
17. Li, H., W. Tao, and E. Lai. 1996. Characterization of the structure and function of the gene for transcription factor BF-1, an essential regulator of forbrain development. Mol. Brain Res. 37:96-104.
18. Liu, F., C. Pouponot, and J. Massague. 1997. Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes. Genes Dev. 11:3157-3167.
19. Massague, J., A. Hata, and K. Liu. 1997. TGFb singalling through the Smad pathway. Trends Cell Biol. 7:187-192.
20. Miyajima, N. R. Horiuchi, Y. Shibuya, S.-I. Fukushige, K.-I. Matsubara, K. Toyoshima, and T. Yamamoto. 1989. Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus. Cell 57:31-39.
21. Saito, N., Y. Okada, Y. Noda, Y. Kinoshita, S. Kondo, N. N. Hirokawa. 1997. KIFC2is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles. Neuron 18: 425-438.
22. Sussman, D., and G. Milman. 1984. Short-term, high-efficiency expression of transfected DNA. Mol. Cell. Biol. 4:1641-1643.
23. Weinstein, D., I. A. Altaba, W. Chen, P. Hoodless, V. Prezioso, T. Jessell, and J. Darnell. 1994. The winged-helix transcription factor HNF-3gamma is required for notochord development in the mouse embryo. Cell 78:575-588.
24. Winnier, G., L. Hargett, and B. Hogan. 1997. The winged helix transcription factor MFHI is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Genes Dev. 11:926-940.
25. Xuan, S., C. Baptista, G. Balas, W. Tao, V. Soares, and E. Lai. 1995. Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron 14:1141-1152.
26. Zhou, S., L. Zawel, C. Lengauer, K. Kinzler, and B. Vogelstein. 1998. Characterization of human FAST-1, a TGFβ and activin signal transducer. Mol. Cell 2:121-127.