Tonic, fortifier and aphrodisiac: Adaptogens in the Brazilian folk medicine

Revista Brasileira de Farmacognosia

Volumn 21, Issue 4, 2011, Pages 754-763

  Mendes, Fúlvio R ^a  

^a UNIVERSIDADE FEDERAL DO ABC   (Brazil)

Author keywords

Adaptogens; Anti stress; Aphrodisiac; Ethnopharmacology; Folk medicine; Tonics

Indexed keywords

ADAPTOGEN; HERBACEOUS AGENT; UNCLASSIFIED DRUG;

ARTICLE; BRAZILIAN FOLK MEDICINE; CATUABA; CHEMICAL COMPOSITION; DAMIANA; DRUG MECHANISM; GINSENG; GUARANA; MEDICINAL PLANT; MUIRAPUAMA; NONHUMAN; PFAFFIA; TRADITIONAL MEDICINE;

EID: 80051936700     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2011005000097     Document Type: Article

References (69)

1. Albert MS, Knoefel JE 1994. Clinical neurology of aging. 2 ed. New York: Oxford University Press.
2. Arletti R, Benelli A, Cavazzuti E, Scarpetta G, Bertolini A 1999. Stimulating property of Turnera diffusa and Pfaffia paniculata extracts on the sexual behavior of male rats. Psychopharmacology 143: 15-19.
3. Bezerra AG, Mendes FR, Tabach R, Carlini EA 2011. Effects of a hydroalcoholic extract of Turnera diffusa Willd. ex Schult., Turneraceae, in tests for adaptogenic activity. Rev Bras Farmacogn 21: 121-127.
4. Brekhman II, Dardymov IV 1969. New substances of plants origin which increase nonspecific resistence. Annu Rev Pharmacol 9: 419-430.
5. Bridi R, Crossetti FP, Steffen VM, Henriques AT 2001. The antioxidant activity of standardized extract of Ginkgo biloba (EGB 761) in rats. Phytother Res 15: 449-451.
6. Brown MR, Koob GF, Rivier C 1990. Stress: neurobiology and neuroendocrinology. New York: Marcel Dekker Inc.
7. Campos MM, Fernandes ES, Ferreira J, Santos AR, Calixto JB 2005. Antidepressant-like effects of Trichilia catigua (catuaba) extract: evidence for dopaminergic-mediated mechanisms. Psychopharmacology (Berl) 182: 45-53.
8. Capra F 1993. O modelo biomédico. In Capra F (ed.) O ponto de mutação. São Paulo: Editora Cultrix, p. 116-155.
9. Carlini EA 1991. Efeito adaptógeno ou resistógeno de algumas plantas. In Buchillet D (ed) Medicinas tradicionais e medicina ocidental na Amazônia. Belém: Edições Cejup, p. 45-59.
10. Carrasco GA, van de Kar LD 2003. Neuroendocrine pharmacology of stress. Eur J Pharmacol 463: 235-272.
11. Chan K 2005. Chinese medicinal materials and their interface with Western medical concepts. J Ethnopharmacol 96: 1-18.
12. Chen TS, Liou SY, Chang YL 2008. Antioxidant evaluation of three adaptogen extracts. Am J Chin Med 36: 1209-1217.
13. Chowdhuri DK, Parmar D, Kakkar P, Shukla R, Seth PK, Srimal RC 2002. Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytother Res 16: 639-645.
14. Corrêa MP 1984. Dicionário das plantas úteis do Brasil e das exóticas cultivadas. Brasília: Ministério da agricultura/Instituto brasileiro de desenvolvimento florestal.
15. da Silva AL, Piato ALS, Bardini S, Netto CA, Nunes DS, Elisabetsky E 2004. Memory retrieval improvement by Ptychopetalum olacoides in young and aging mice. J Ethnopharmacol 95: 199-203.
16. Dahanukar SA, Thatte UM 1997. Current status of Ayurveda in phytomedicine. Phytomedicine 4: 359-368.
17. Davis L, Kuttan G 2000. Immunomodulatory activity of Withania somnifera. J Ethnopharmacol 71: 193-200.
18. Davydov M, Krikorian AD 2000. Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look. J Ethnopharmacol 72: 345-393.
19. Di Matteo V, Esposito E 2003. Biochemical and therapeutic effects of antioxidants in the treatment of Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Curr Drug Targets CNS Neurol Disord 2: 95-107.
20. Ducke A 1966. A catuaba na botânica sistemática científica e pseudo-científica. Rev Bras Farm 47: 267-271.
21. Elisabetsky E, Siqueira IR 1998. Is there a psychopharmacological meaning for traditional tonics? In Prendergast HDV, Etkin NL, Harris DR, Houghton PJ (eds.) Plants for food and medicine. London: Royal Botanical Gardens, p. 373-385.
22. Espínola EB, Dias RF, Mattei R, Carlini EA 1997. Pharmacological activity of guarana (Paullinia cupana Mart.) in laboratory animals. J Ethnopharmacol 55: 223-229.
23. Estrada-Reyes R, Ortiz-López P, Gutiérrez-Ortíz J, Martínez- Mota L 2009. Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males. J Ethnopharmacol 123: 423-429.
24. Freitas CS, Baggio CH, Da Silva-Santos JE, Rieck L, Santos CAM, Júnior CC, Ming LX, Cortez DAG, Marques MCA 2004. Involvement of nitric oxide in the gastroprotective effects of an aqueous extract of Pfaffia glomerata (Spreng) Pedersen, Amaranthaceae, in rats. Life Sci 74: 1167-1179.
25. Fulder S 1980. The root of being. Ginseng and the pharmacology of harmony. London: Huchinson and Co.
26. Galvão SMP 2003. Heteropterys aphrodisiaca O. Mach. (extrato BST 0298): estudos pré-clínicos farmacológicos e toxicológicos. São Paulo, 163p. Tese de Doutorado, Universidade Federal de São Paulo.
27. Galvão SMP, Marques LC, Oliveira MGM, Carlini EA 2002. Heteropterys aphrodisiaca (extract BST0298): a Brazilian plant that improves memory in aged rats. J Ethnopharmacol 79: 305-311.
28. Galvão SMP, Mendes FR, Oliveira GM, Mattei R, Carlini ELA 2004/2005. Possíveis efeitos adaptógenos da Heteropterys aphrodisiaca O. Mach. - extrato BST 0298: uma planta da área do pantanal brasileiro. Arq Bras Fitomed Cient 2: 41-55.
29. Hancke JL, Burgos RA, Ahumada F 1999. Schisandra chinensis (Turcz.) Baill. Fitoterapia 70: 451-471.
30. Harman D 1994. Free-radical theory of aging. Increasing the functional life span. Ann NY Acad Sci 717: 1-15.
31. Kennedy DO, Haskell CF, Robertson B, Reay J, Brewster-Maund C, Luedemann J, Maggini S, Ruf M, Zangara A, Scholey AB 2008. Improved cognitive performance and mental fatigue following a multi-vitamin and mineral supplement with added guarana (Paullinia cupana). Appetite 50: 506-513.
32. Kennedy DO, Haskell CF, Wesnes KA, Scholey AB 2004. Improved cognitive performance in human volunteers following administration of guarana (Paullinia cupana) extract: comparison and interaction with Panax ginseng. Pharmacol Biochem Behav 79: 401-411.
33. Kimura Y, Sumiyoshi M 2004. Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity and corticosterone level in forced swimming stressed mice. J Ethnopharmacol 95: 447-453.
34. Kumar S, Sharma A 2005. Anti-anxiety activity studies of various extracts of Turnera aphrodisiaca Ward. J Herb Pharmacother 5: 13-21.
35. Kvetnansky R, Pacak K, Fukuhara K, Viskupic E, Hiremagalur B, Nankova B, Goldstein DS, Sabban EL, Kopin IJ 1995. Sympathoadrenal system in stress; interaction with the hypothalamic-pituitary-adrenocortical system. Ann NY Acad Sci 771: 131-158.
36. Lin CC, Huang PC 2000. Antioxidant and hepatoprotective effects of Acathopanax senticosus. Phytother Res 14: 489-494.
37. Liu JX, Cong WH, Xu L, Wang JN 2004. Effect of combination of extracts of ginseng and Ginkgo biloba on acetylcholine in amyloid beta-protein-treated rats determined by an improved HPLC. Acta Pharmacol Sin 25: 1118-1123.
38. Lorenzi H, Matos FJA 2002. Plantas medicinais no Brasil: nativas e exóticas cultivadas. Nova Odessa: Instituto Plantarum.
39. Marques LC 1998. Avaliação da ação adaptógena das raízes de Pfaffia glomerata (Sprengel) Pedersen - Amaranthaceae. São Paulo, 145p. Tese de Doutorado, Universidade Federal de São Paulo.
40. Marques LC, Danucalov MA, Torres F, Galduróz JCF, Carlini ELA, Silva AC 2002. Estudo clínico duplo-cego de extrato padronizado (BNT-08) das raízes de Pfaffia glomerata (Spreng.) Pedersen: avaliação do efeito tônico em atividade física. Rev Bras Farmacogn 12: 44-47.
41. Marques LC, Galvão SMP, Espínola E, Dias RF, Menezes MGM, Carlini ELA 2004. Psychopharmacological assessment of Pfaffia glomerata roots (extract BNT-08) in rodents. Phytother Res 18: 566-572.
42. Mattei R, Dias RF, Espínola EB, Carlini EA, Barros SBM 1998. Guarana (Paullinia cupana): toxic behavioral effects in laboratory animals and antioxidant activity in vitro. J Ethnopharmacol 60: 111-116.
43. Mediratta PK, Sharma KK, Singh S 2002. Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action. J Ethnopharmacol 80: 15-20.
44. Mendes FR 2005. Avaliação farmacológica da carqueja (Baccharis trimera) e do cipó-caboclo (Davilla rugosa), duas plantas brasileiras utilizadas popularmente como tônicas, em testes para ação adaptógena. São Paulo, 156p. Tese de doutorado, Universidade Federal de São Paulo.
45. Mendes FR, Carlini EA 2007. Brazilian plants as possible adaptogens: an ethnopharmacological survey of books edited in Brazil. J Ethnopharmacol 109: 493-500.
46. Moosmann B, Behl C 2002. Antioxidants as treatment for neurodegenerative disorders. Expert Opin Investig Drugs 11: 1407-1435.
47. Pang Z, Pan F, He S 1996. Ginkgo biloba L.: history, current status and future prospects. J Altern Complement Med 2: 359-363.
48. Panossian A, Wagner H 2005. Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration. Phytother Res 19: 819-838.
49. Panossian A, Gabrielian E, Wagner H 1997. Plant adaptogens. II. Bryonia as an adaptogen. Phytomedicine 4: 85-99.
50. Panossian A, Hambardzumyan M, Hovhanissyan A, Wikman G 2007. The adaptogens Rhodiola and Schizandra modify the response to immobilization stress in rabbits by suppressing the increase of phosphorylated stressactivated protein kinase, nitric oxide and cortisol. Drug Target Insights 1: 39-54.
51. Panossian A, Wikman G 2005. Effect of adaptogens on the central nervous system. Arq Bras Fitomed Cient 2: 109-131.
52. Panossian A, Wikman G 2009. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol 4: 198-219.
53. Panossian A, Wikman G, Kaur G, Asea A 2009. Adaptogens exert a stress-protective effect by modulation of expression of molecular chaperones. Phytomedicine 16: 617-622.
54. Panossian A, Wikman G, Wagner H 1999. Plant adaptogens. III. Earlier and more recent aspects and concepts on their mode of action. Phytomedicine 6: 287-300.
55. Petkov VD, Belcheva S, Petkov VV 2003. Behavioral effects of Ginkgo biloba L., Panax ginseng C.A. Mey. and Gincosan®. Am J Chin Med 31: 841-855.
56. Piato AL, Detanico BC, Linck VM, Herrmann AP, Nunes DS, Elisabetsky E 2010. Anti-stress effects of the tonic Ptychopetalum olacoides (Marapuama) in mice. Phytomedicine 17: 248-253.
57. Ramachandran U, Divekar HM, Grover SK, Srivastava KK 1990. New experimental model for the evaluation of adaptogenic products. J Ethnopharmacol 29: 275-281.
58. Rege NN, Thatte UM, Dahanukar SA 1999. Adaptogenic properties of six Rasayana herbs used in Ayurvedic medicine. Phytother Res 13: 275-291.
59. Russo E 2001. Adaptogens. In Russo E (ed.) Handbook of psychotropic herbs. A scientific analysis of herbal remedies for psychiatric conditions. New York: The Haworth Press, Inc., p. 181-198.
60. Santos RF, Galduróz JCF, Balbieri A, Castiglioni MLV, Ytaya LY, Bueno OFA 2003. Cognitive performance, SPECT, and blood viscosity in elderly non-demented people using Ginkgo biloba. Pharmacopsychiatry 36: 127-133.
61. Siqueira IR, Cimarosti H, Fochesatto C, Nunes DS, Salbego C, Elisabetsky E, Netto CA 2004. Neuroprotective effects of Ptychopetalum olacoides Bentham (Olacaceae) on oxygen and glucose deprivation induced damage in rat hippocampal slices. Life Sci 75: 1897-1906.
62. Siqueira IR, Fochesatto C, Torres IL, da Silva AL, Nunes DS, Elisabetsky E, Netto CA 2007. Antioxidant activities of Ptychopetalum olacoides (muirapuama) in mice brain. Phytomedicine 14: 763-769.
63. Spinella M 2002. The importance of pharmacological synergy in psychoactive herbal medicines. Altern Med Rev 7: 130-137.
64. Ulrich-Merzenich G, Zeitler H, Jobst D, Panek D, Vetter H, Wagner H 2007. Application of the "-omic-" technologies" in phytomedicine. Phytomedicine 14: 70-82.
65. Ven Murthy MR, Ranjekar PK, Ramassamy C, Deshpande M 2010. Scientific basis for the use of Indian ayurvedic medicinal plants in the treatment of neurodegenerative disorders: ashwagandha. Cent Nerv Syst Agents Med Chem 10: 238-246.
66. Viana AF, Maciel IS, Motta EM, Leal PC, Pianowski L, Campos MM, Calixto JB 2009. Antinociceptive activity of Trichilia catigua hydroalcoholic extract: new evidence on its dopaminergic effects. Evid Based Complement Alternat Med: (doi:10.1093/ecam/nep144).
67. Wagner H, Nörr H, Winterhoff H 1994. Plant adaptogens. Phytomedicine 1: 63-76.
68. Wagner HKM 1995. Immunostimulants and adaptogens from plants. In Arnason JT, Mata R, Romeo JT (eds.) Phytochemistry of medicinal plants. New York: Plenum Press, p. 1-18.
69. Wahlström M 1987. Adaptogens. Nature's key to well-being. Gotemburg: Utgivare Publisher.