Pharmacological activity of Guarana (Paullinia cupana Mart.) in laboratory animals

Journal of Ethnopharmacology

Volumn 55, Issue 3, 1997, Pages 223-229

  Espinola, E B ^a   Dias, R F ^a   Mattei, R ^b   Carlini, E A ^b  

^a FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Guarana; Learning; Memory; Paullinia cupana; Physical capacity

Indexed keywords

CAFFEINE; GUARANA; SCOPOLAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; ETHNOPHARMACOLOGY; GINSENG; HERB; INTRAPERITONEAL DRUG ADMINISTRATION; LEARNING; LIFESPAN; MALE; MEMORY CONSOLIDATION; MOUSE; MUSCLE FATIGUE; NONHUMAN; ORAL DRUG ADMINISTRATION; PASSIVE AVOIDANCE; PHYSICAL CAPACITY;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; CAFFEINE; EXERTION; LONGEVITY; MALE; MEMORY; MICE; PANAX; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, WISTAR; SCOPOLAMINE;

EID: 0030982882     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(96)01506-1     Document Type: Article

References (18)

1. Bombardelli, E. Cristoni and Lietti, A. (1980) In: Proc. 3rd Int. Ginseng Symp., Korea Ginseng and Tobacco Research Institute, Daejeon, Korea.
2. Bueno. O.F.A., Oliveira, M.G.M., Pomarico, A.C. and Gugliano E.B. (1993) A dissociation between the proactive ECS effects on inhibitory avoidance learning and on classical fear conditioning. Behavioral and Neural Biology 59, 180-185.
3. Carlini, E.A. and Kramer, C. (1965) Effects of Cannabis sativa (marihuana) on maze performance of the rat. Psychopharmacologia 7, 175-181.
4. Chen, C., Jin R.M., Li. Y., Sheng, Y., Zhou, M., Chen, S. and Zhou, Z. (1991) Improvement of memory in mice by extracts from leaves of Ginkgo biloba L. China Journal of Chinese Materia Medica 16, 681-683.
5. Galdurȯz, J.C.F. and Carlini, E.A. (1994) Acute effects of the Paullinia cupana, 'guarana'. on the cognition of normal volunteers. Sào Paulo Medical Journal 112, 607-611.
6. Henman, A.R. (1982) Guarana (Paullinia cupana var. sorbilis): ecological and social perspective on an economic plant of the central Amazon Basin. Journal of Ethnopharmacology 6, 311-338.
7. Henman, A.R. (1986) Vida Natural - O Guarana: Sua Cultura, Propriedades, Formas de Preparação e Uso. Ed. Global Ground, 2nd edition, pp. 77.
8. Kaku, T., Miyata, T., Uruno, T., Sako, I. and Kinoshita, A. (1975) Chemico-pharmacological studies on saponins of Panax ginseng C. A. Meyer. Arzneimittel Forschung (Drug Research) 25, 539 547.
9. Kulkarni, S.K. and Verma, A. (1992) Evidence for nootropic effect of BR-16A (Mentat), a herbal psychotropic preparation, in mice. Indian Journal of Physiology and Pharmacology 36, 29-34.
10. Lenégre, A., Chermat, R., Avril, I., Steru, L. and Porsolt, R.D. (1988) Specificity of piracetam's anti-amnesic activity in three models of amnesia in the mouse. Pharmacology Biochemistry and Behavior 29, 625-629.
11. Mattei, R., Dias, R.F., Espinola, E.B., Carlini, E.A. and Barros, S.B.M. (1996) Guarana (Paullinia cupana): toxic behavioral effects in laboratory animals and antioxidant activity in vitro (submitted for publication).
12. Nishiyama, N., Wang. Y.L. and Saito, H. (1995) Beneficial effects of S-l13m, a novel herbal prescription, on learning impairment model in mice. Biological and Pharmaceutical Bulletin 18, (11), 1498-1503.
13. Nishizawa, K., Saito, H. and Nishiyama, N. (1991) Effects of Kamikihi-To, a traditional Chinese medicine, on learning and memory performance in mice. Phytotherapy Research 5, 97-102.
14. Owen, R.T. (1981) Ginseng: a pharmacological profile. Drugs of Today 17, 339-351.
15. Porsolt, R.O., Bertin, A. and Jaefre, M. (1977) Behavioral dispair in mice: a primary screening test for antidepressants. Archives Internationales Pharmacodinamie Therapie 229, 327-336.
16. Simeray, J., Chaumont, J.P., Bevalot, F. and Vaquette, J. (1982) Les proprietés antifongiques des cistacées et plus particuli̇rement de Cistus laurifolius L.: rôle des tanins non hydrolysables. Fitoterapia 53, 45-48.
17. Wagner, H., Norr, H. and Winterhoff, H. (1994) Plant adaptogens. Phytomedicine 1, 63-76.
18. Yoshizawa, S., Horiuchi, T., Fujiki, H., Yoshida, T., Okuda, T and Sugimura, T. (1987) Antitumor promoting activity of ( - )-epigallocatechin gallate, the main constituent of tannin in green tea. Phytotherapy Research 1, 44-47.