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Volumn 26, Issue 9, 2011, Pages 2306-2315

Sam68 mediates leptin-stimulated growth by modulating leptin receptor signaling in human trophoblastic JEG-3 cells

Author keywords

LEPR signaling; leptin; placenta; Sam68; trophoblast

Indexed keywords

DNA; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SAM68; STAT3 PROTEIN; TYROSINE;

EID: 80051934435     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der187     Document Type: Article
Times cited : (11)

References (60)
  • 1
    • 33747370388 scopus 로고    scopus 로고
    • SUMO modification of Sam68 enhances its ability to repress cyclin D1 expression and inhibits its ability to induce apoptosis
    • Babic I, Cherry E, Fujita DJ. SUMO modification of Sam68 enhances its ability to repress cyclin D1 expression and inhibits its ability to induce apoptosis. Oncogene 2006;25:4955-4964.
    • (2006) Oncogene , vol.25 , pp. 4955-4964
    • Babic, I.1    Cherry, E.2    Fujita, D.J.3
  • 2
    • 0034640508 scopus 로고    scopus 로고
    • Activation of downstream signals by the long form of the leptin receptor
    • DOI 10.1074/jbc.275.19.14563
    • Banks AS, Davis SM, Bates SH, Myers MG Jr. Activation of downstream signals by the long form of the leptin receptor. J Biol Chem 2000; 275:14563-14572. (Pubitemid 30339746)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.19 , pp. 14563-14572
    • Banks, A.S.1    Davis, S.M.2    Bates, S.H.3    Myers Jr., M.G.4
  • 4
    • 34347348168 scopus 로고    scopus 로고
    • The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells
    • DOI 10.1038/sj.onc.1210224, PII 1210224
    • Busa R, Paronetto MP, Farini D, Pierantozzi E, Botti F, Angelini DF, Attisani F, Vespasiani G, Sette C. The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells. Oncogene 2007;26:4372-4382. (Pubitemid 47014462)
    • (2007) Oncogene , vol.26 , Issue.30 , pp. 4372-4382
    • Busa, R.1    Paronetto, M.P.2    Farini, D.3    Pierantozzi, E.4    Botti, F.5    Angelini, D.F.6    Attisani, F.7    Vespasiani, G.8    Sette, C.9
  • 6
    • 33747470228 scopus 로고    scopus 로고
    • Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane)
    • DOI 10.1002/ijc.21967
    • Chakravarti N, Myers JN, Aggarwal BB. Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane). Int J Cancer 2006; 119:1268-1275. (Pubitemid 44258799)
    • (2006) International Journal of Cancer , vol.119 , Issue.6 , pp. 1268-1275
    • Chakravarti, N.1    Myers, J.N.2    Aggarwal, B.B.3
  • 8
    • 0037244282 scopus 로고    scopus 로고
    • Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1
    • DOI 10.1091/mbc.E02-08-0484
    • Cote J, Boisvert FM, Boulanger MC, Bedford MT, Richard S. Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1. Mol Biol Cell 2003;14:274-287. (Pubitemid 36106036)
    • (2003) Molecular Biology of the Cell , vol.14 , Issue.1 , pp. 274-287
    • Cote, J.1    Boisvert, F.-M.2    Boulanger, M.-C.3    Bedford, M.T.4    Richard, S.5
  • 9
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995;378:785-789. (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 12
    • 30044434035 scopus 로고    scopus 로고
    • Intracellular signalling pathways activated by leptin
    • DOI 10.1042/BJ20051578
    • Fruhbeck G. Intracellular signalling pathways activated by leptin. Biochem J 2006;393:7-20. (Pubitemid 43049298)
    • (2006) Biochemical Journal , vol.393 , Issue.1 , pp. 7-20
    • Fruhbeck, G.1
  • 13
    • 0030934461 scopus 로고    scopus 로고
    • Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling
    • DOI 10.1074/jbc.272.10.6214
    • Fusaki N, Iwamatsu A, Iwashima M, Fujisawa J. Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling. J Biol Chem 1997;272:6214-6219. (Pubitemid 27118091)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.10 , pp. 6214-6219
    • Fusaki, N.1    Iwamatsu, A.2    Iwashima, M.3    Fujisawa, J.-I.4
  • 15
    • 62849109985 scopus 로고    scopus 로고
    • Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells
    • Gao J, Tian J, Lv Y, Shi F, Kong F, Shi H, Zhao L. Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells. Cancer Sci 2009;100:389-395.
    • (2009) Cancer Sci , vol.100 , pp. 389-395
    • Gao, J.1    Tian, J.2    Lv, Y.3    Shi, F.4    Kong, F.5    Shi, H.6    Zhao, L.7
  • 16
    • 0030956390 scopus 로고    scopus 로고
    • The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line
    • DOI 10.1210/me.11.4.393
    • Ghilardi N, Skoda RC. The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line. Mol Endocrinol 1997;11:393-399. (Pubitemid 27147006)
    • (1997) Molecular Endocrinology , vol.11 , Issue.4 , pp. 393-399
    • Ghilardi, N.1    Skoda, R.C.2
  • 17
    • 31044439034 scopus 로고    scopus 로고
    • Leptin in pregnancy: An update
    • DOI 10.1095/biolreprod.105.045120
    • Henson MC, Castracane VD. Leptin in pregnancy: an update. Biol Reprod 2006;74:218-229. (Pubitemid 43122272)
    • (2006) Biology of Reproduction , vol.74 , Issue.2 , pp. 218-229
    • Henson, M.C.1    Castracane, V.D.2
  • 18
    • 56049083633 scopus 로고    scopus 로고
    • Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways
    • Jaffe T, Schwartz B. Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways. Int J Cancer 2008;123:2543-2556.
    • (2008) Int J Cancer , vol.123 , pp. 2543-2556
    • Jaffe, T.1    Schwartz, B.2
  • 19
    • 57649137956 scopus 로고    scopus 로고
    • Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways
    • Jiang L, Li Z, Rui L. Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways. J Biol Chem 2008;283:28066-28073.
    • (2008) J Biol Chem , vol.283 , pp. 28066-28073
    • Jiang, L.1    Li, Z.2    Rui, L.3
  • 21
    • 2642689659 scopus 로고    scopus 로고
    • A dual participation of ZAP-70 and scr protein tyrosine kinases is required for TCR-induced tyrosine phosphorylation of sam68 in jurkat T cells
    • DOI 10.1002/eji.1830271235
    • Lang V, Mege D, Semichon M, Gary-Gouy H, Bismuth G. A dual participation of ZAP-70 and scr protein tyrosine kinases is required for TCR-induced tyrosine phosphorylation of Sam68 in Jurkat T cells. Eur J Immunol 1997;27:3360-3367. (Pubitemid 28018033)
    • (1997) European Journal of Immunology , vol.27 , Issue.12 , pp. 3360-3367
    • Lang, V.1    Mege, D.2    Semichon, M.3    Gary-Gouy, H.4    Bismuth, G.5
  • 22
    • 33644663231 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression
    • DOI 10.1074/jbc.M505802200
    • Lukong KE, Larocque D, Tyner AL, Richard S. Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression. J Biol Chem 2005;280:38639-38647. (Pubitemid 43853766)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.46 , pp. 38639-38647
    • Lukong, K.E.1    Larocque, D.2    Tyner, A.L.3    Richard, S.4
  • 24
    • 67651154110 scopus 로고    scopus 로고
    • Sam68 and ERKs regulate leptin-induced expression of OB-Rb mRNA in C2C12 myotubes
    • Maroni P, Citterio L, Piccoletti R, Bendinelli P. Sam68 and ERKs regulate leptin-induced expression of OB-Rb mRNA in C2C12 myotubes. Mol Cell Endocrinol 2009;309:26-31.
    • (2009) Mol Cell Endocrinol , vol.309 , pp. 26-31
    • Maroni, P.1    Citterio, L.2    Piccoletti, R.3    Bendinelli, P.4
  • 25
    • 0035885876 scopus 로고    scopus 로고
    • Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: Possible role of Sam68
    • DOI 10.1006/cimm.2001.1851
    • Martin-Romero C, Sanchez-Margalet V. Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68. Cell Immunol 2001;212:83-91. (Pubitemid 34044539)
    • (2001) Cellular Immunology , vol.212 , Issue.2 , pp. 83-91
    • Martin-Romero, C.1    Sanchez-Margalet, V.2
  • 27
    • 0037069651 scopus 로고    scopus 로고
    • Signal-dependent regulation of splicing via phosphorylation of Sam68
    • DOI 10.1038/nature01153
    • Matter N, Herrlich P, Konig H. Signal-dependent regulation of splicing via phosphorylation of Sam68. Nature 2002;420:691-695. (Pubitemid 36764503)
    • (2002) Nature , vol.420 , Issue.6916 , pp. 691-695
    • Matter, N.1    Herrlich, P.2    Konig, H.3
  • 28
    • 77249131862 scopus 로고    scopus 로고
    • Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin
    • Mauvoisin D, Prevost M, Ducheix S, Arnaud MP, Mounier C. Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin. Mol Cell Endocrinol 2010;319:116-128.
    • (2010) Mol Cell Endocrinol , vol.319 , pp. 116-128
    • Mauvoisin, D.1    Prevost, M.2    Ducheix, S.3    Arnaud, M.P.4    Mounier, C.5
  • 30
    • 77954891467 scopus 로고    scopus 로고
    • ′-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways
    • Maymo JL, Perez Perez A, Duenas JL, Calvo JC, Sanchez-Margalet V, Varone CL. Regulation of placental leptin expression by cyclic adenosine 5′-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways. Endocrinology 2010;151:3738-3751.
    • (2010) Endocrinology , vol.151 , pp. 3738-3751
    • Maymo, J.L.1    Perez Perez, A.2    Duenas, J.L.3    Calvo, J.C.4    Sanchez-Margalet, V.5    Varone, C.L.6
  • 31
    • 2342444310 scopus 로고    scopus 로고
    • Leptin receptor signaling and the regulation of mammalian physiology
    • Myers MG Jr. Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog Horm Res 2004;59:287-304.
    • (2004) Recent Prog Horm Res , vol.59 , pp. 287-304
    • Myers Jr., M.G.1
  • 32
    • 43549114292 scopus 로고    scopus 로고
    • Mechanisms of leptin action and leptin resistance
    • DOI 10.1146/annurev.physiol.70.113006.100707
    • Myers MG, Cowley MA, Munzberg H. Mechanisms of leptin action and leptin resistance. Annu Rev Physiol 2008;70:537-556. (Pubitemid 351738191)
    • (2008) Annual Review of Physiology , vol.70 , pp. 537-556
    • Myers, M.G.1    Cowley, M.A.2    Munzberg, H.3
  • 33
    • 0035986594 scopus 로고    scopus 로고
    • Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling
    • Najib S, Sanchez-Margalet V. Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling. J Cell Biochem 2002;86:99-106.
    • (2002) J Cell Biochem , vol.86 , pp. 99-106
    • Najib, S.1    Sanchez-Margalet, V.2
  • 35
    • 0037096988 scopus 로고    scopus 로고
    • 727 phosphorylation and DNA binding
    • DOI 10.1042/BJ20020295
    • O'Rourke L, Shepherd PR. Biphasic regulation of extracellular-signal- regulated protein kinase by leptin in macrophages: role in regulating STAT3 Ser727 phosphorylation and DNA binding. Biochem J 2002; 364:875-879. (Pubitemid 34680866)
    • (2002) Biochemical Journal , vol.364 , Issue.3 , pp. 875-879
    • O'Rourke, L.1    Shepherd, P.R.2
  • 36
    • 30044434258 scopus 로고    scopus 로고
    • The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysemes in mouse spermatocytes
    • DOI 10.1091/mbc.E05-06-0548
    • Paronetto MP, Zalfa F, Botti F, Geremia R, Bagni C, Sette C. The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes. Mol Biol Cell 2006;17:14-24. (Pubitemid 43049457)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.1 , pp. 14-24
    • Paronetto, M.P.1    Zalfa, F.2    Botti, F.3    Geremia, R.4    Bagni, C.5    Sette, C.6
  • 37
    • 33947712084 scopus 로고    scopus 로고
    • The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x
    • DOI 10.1083/jcb.200701005
    • Paronetto MP, Achsel T, Massiello A, Chalfant CE, Sette C. The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x. J Cell Biol 2007;176:929-939. (Pubitemid 46506967)
    • (2007) Journal of Cell Biology , vol.176 , Issue.7 , pp. 929-939
    • Paronetto, M.P.1    Achsel, T.2    Massiello, A.3    Chalfant, C.E.4    Sette, C.5
  • 38
    • 41949109645 scopus 로고    scopus 로고
    • Dynamic expression of the RNA-binding protein Sam68 during mouse pre-implantation development
    • Paronetto MP, Bianchi E, Geremia R, Sette C. Dynamic expression of the RNA-binding protein Sam68 during mouse pre-implantation development. Gene Expr Patterns 2008; 8:311-322.
    • (2008) Gene Expr Patterns , vol.8 , pp. 311-322
    • Paronetto, M.P.1    Bianchi, E.2    Geremia, R.3    Sette, C.4
  • 44
    • 34548636476 scopus 로고    scopus 로고
    • Arginine methylation of Sam68 and SLM proteins negatively regulates their poly(U) RNA binding activity
    • DOI 10.1016/j.abb.2007.07.017, PII S0003986107003761
    • Rho J, Choi S, Jung CR, Im DS. Arginine methylation of Sam68 and SLM proteins negatively regulates their poly(U) RNA binding activity. Arch Biochem Biophys 2007;466:49-57. (Pubitemid 47405083)
    • (2007) Archives of Biochemistry and Biophysics , vol.466 , Issue.1 , pp. 49-57
    • Rho, J.1    Choi, S.2    Jung, C.-R.3    Im, D.-S.4
  • 45
    • 0028947757 scopus 로고
    • Association of p62, a multifunctional SH2-and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1
    • Richard S, Yu D, Blumer KJ, Hausladen D, Olszowy MW, Connelly PA, Shaw AS. Association of p62, a multifunctional SH2-and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1. Mol Cell Biol 1995;15:186-197.
    • (1995) Mol Cell Biol , vol.15 , pp. 186-197
    • Richard, S.1    Yu, D.2    Blumer, K.J.3    Hausladen, D.4    Olszowy, M.W.5    Connelly, P.A.6    Shaw, A.S.7
  • 47
    • 38349070272 scopus 로고    scopus 로고
    • Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis
    • Richard S, Vogel G, Huot ME, Guo T, Muller WJ, Lukong KE. Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis. Oncogene 2008;27:548-556.
    • (2008) Oncogene , vol.27 , pp. 548-556
    • Richard, S.1    Vogel, G.2    Huot, M.E.3    Guo, T.4    Muller, W.J.5    Lukong, K.E.6
  • 49
    • 0035838266 scopus 로고    scopus 로고
    • Human leptin signaling in human peripheral blood mononuclear cells: Activation of the JAK-STAT pathway
    • DOI 10.1006/cimm.2001.1815
    • Sanchez-Margalet V, Martin-Romero C. Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway. Cell Immunol 2001;211:30-36. (Pubitemid 32917755)
    • (2001) Cellular Immunology , vol.211 , Issue.1 , pp. 30-36
    • Sanchez-Margalet, V.1    Martin-Romero, C.2
  • 50
    • 0343247114 scopus 로고    scopus 로고
    • P68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K
    • DOI 10.1016/S0014-5793(99)00887-X, PII S001457939900887X
    • Sanchez-Margalet V, Najib S. p68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K. FEBS Lett 1999; 455:307-310. (Pubitemid 29333057)
    • (1999) FEBS Letters , vol.455 , Issue.3 , pp. 307-310
    • Sanchez-Margalet, V.1    Najib, S.2
  • 51
    • 0035950412 scopus 로고    scopus 로고
    • Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling
    • DOI 10.1016/S0303-7207(01)00587-1, PII S0303720701005871
    • Sanchez-Margalet V, Najib S. Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling. Mol Cell Endocrinol 2001; 183:113-121. (Pubitemid 32938517)
    • (2001) Molecular and Cellular Endocrinology , vol.183 , Issue.1-2 , pp. 113-121
    • Sanchez-Margalet, V.1    Najib, S.2
  • 52
    • 0028967845 scopus 로고
    • Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1
    • Sanchez-Margalet V, Goldfine ID, Truitt K, Imboden J, Sung CK. Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1. Mol Endocrinol 1995;9:435-442.
    • (1995) Mol Endocrinol , vol.9 , pp. 435-442
    • Sanchez-Margalet, V.1    Goldfine, I.D.2    Truitt, K.3    Imboden, J.4    Sung, C.K.5
  • 56
    • 77749286131 scopus 로고    scopus 로고
    • Sam68: A new STAR in the male fertility firmament
    • Sette C, Messina V, Paronetto MP. Sam68: a new STAR in the male fertility firmament. J Androl 2010;31:66-74.
    • (2010) J Androl , vol.31 , pp. 66-74
    • Sette, C.1    Messina, V.2    Paronetto, M.P.3
  • 57
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid
    • DOI 10.1016/0003-2697(85)90442-7
    • Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. Measurement of protein using bicinchoninic acid. Anal Biochem 1985; 150:76-85. (Pubitemid 16258399)
    • (1985) Analytical Biochemistry , vol.150 , Issue.1 , pp. 76-85
    • Smith, P.K.1    Krohn, R.I.2    Hermanson, G.T.3
  • 58
    • 0028963413 scopus 로고
    • P62 association with RNA is regulated by tyrosine phosphorylation
    • Wang LL, Richard S, Shaw AS. P62 association with RNA is regulated by tyrosine phosphorylation. J Biol Chem 1995;270:2010-2013.
    • (1995) J Biol Chem , vol.270 , pp. 2010-2013
    • Wang, L.L.1    Richard, S.2    Shaw, A.S.3
  • 59
    • 0001123864 scopus 로고    scopus 로고
    • JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response
    • Wang LH, Kirken RA, Erwin RA, Yu CR, Farrar WL. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response. J Immunol 1999; 162:3897-3904. (Pubitemid 29314768)
    • (1999) Journal of Immunology , vol.162 , Issue.7 , pp. 3897-3904
    • Wang, L.H.1    Kirken, R.A.2    Erwin, R.A.3    Yu, C.-R.4    Farrar, W.L.5
  • 60
    • 34447549109 scopus 로고    scopus 로고
    • Method to Enhance Transfection Efficiency of Cell Lines and Placental Fibroblasts
    • DOI 10.1016/j.placenta.2007.01.012, PII S0143400407000161
    • Zhang M, Guller S, Huang Y. Method to enhance transfection efficiency of cell lines and placental fibroblasts. Placenta 2007;28:779-782. (Pubitemid 47078842)
    • (2007) Placenta , vol.28 , Issue.8-9 , pp. 779-782
    • Zhang, M.1    Guller, S.2    Huang, Y.3


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