Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells

Journal of Immunology

Volumn 187, Issue 4, 2011, Pages 1977-1985

  Mattapallil, Mary J ^a   Silver, Phyllis B ^a   Mattapallil, Joseph J ^b   Horai, Reiko ^a   Karabekian, Zaruhi ^a,f   McDowell, J Hugh ^c   Chan, Chi Chao ^a   James, Eddie A ^d   Kwok, William W ^d   Sen, H Nida ^a   Nussenblatt, Robert B ^a   David, Chella S ^e   Caspi, Rachel R ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d BENAROYA RESEARCH INSTITUTE   (United States)

^e MAYO GRADUATE SCHOOL   (United States)

^f GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CELL PROTEIN; EPITOPE; HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN; PEPTIDE M; PEPTIDE N; RETINA S ANTIGEN; TETRAMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CONTROLLED STUDY; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; IMMUNOPATHOGENESIS; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE ANALYSIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TRANSGENIC MOUSE; UVEITIS;

ALLELES; ANIMALS; AUTOANTIGENS; AUTOIMMUNE DISEASES; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; EPITOPES, T-LYMPHOCYTE; EYE PROTEINS; GENETIC PREDISPOSITION TO DISEASE; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; IMMUNOLOGIC MEMORY; MICE; MICE, TRANSGENIC; RETINA; UVEITIS;

EID: 80051924280     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101247     Document Type: Article

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