1,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 18, 2011, Pages 5301-5304

  Renton, Paul ^a   Speed, Joanne ^a   Maddaford, Shawn ^a   Annedi, Subhash C ^a   Ramnauth, Jailall ^a   Rakhit, Suman ^a   Andrews, John ^a  

^a NeurAxon Inc   (Canada)

Author keywords

1,5 Disubstitued indole derivatives; Nitric oxide; Nitric oxide synthase; Nitric oxide synthase inhibitors; Selective neuronal nitric oxide synthase inhibitors

Indexed keywords

INDOLE DERIVATIVE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ALKYLATION; ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; INDOLES; MOLECULAR STRUCTURE; NITRIC OXIDE SYNTHASE TYPE I; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80051919729     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.07.022     Document Type: Article

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