-
1
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
DOI 10.1038/nrc1074
-
Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: Mechanisms of action and clinical strategies. Nat Rev Cancer 2003;3:330-8. (Pubitemid 37328853)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.5
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
2
-
-
1442290323
-
Thymidylate-synthase expression and prognosis in colorectal cancer: A systematic review and meta-analysis
-
DOI 10.1200/JCO.2004.05.064
-
Popat S, Matakidou A, Houlston RS. Thymidylate synthase expression and prognosis in colorectal cancer: A systematic review and meta-analysis. J Clin Oncol 2004;22: 529-36. (Pubitemid 41079782)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.3
, pp. 529-536
-
-
Popat, S.1
Matakidou, A.2
Houlston, R.S.3
-
3
-
-
0034048729
-
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
-
Salonga D, Danenberg KD, Johnson M, Metzger R, Groshen S, Tsao-Wei DD, et al. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 2000;6: 1322-7. (Pubitemid 30226214)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.4
, pp. 1322-1327
-
-
Salonga, D.1
Danenberg, K.D.2
Johnson, M.3
Metzger, R.4
Groshen, S.5
Tsao-Wei, D.D.6
Lenz, H.-J.7
Leichman, C.G.8
Leichman, L.9
Diasio, R.B.10
Danenberg, P.V.11
-
4
-
-
1642327569
-
Characterization of p53 Wild-Type and Null Isogenic Colorectal Cancer Cell Lines Resistant to 5-Fluorouracil, Oxaliplatin, and Irinotecan
-
DOI 10.1158/1078-0432.CCR-03-0362
-
Boyer J, McLean EG, Aroori S, Wilson P, McCulla A, Carey PD, et al. Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan. Clin Cancer Res 2004;10:2158-67. (Pubitemid 38375578)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.6
, pp. 2158-2167
-
-
Boyer, J.1
McLean, E.G.2
Aroori, S.3
Wilson, P.4
McCulla, A.5
Carey, P.D.6
Longley, D.B.7
Johnston, P.G.8
-
5
-
-
0037457481
-
Disulfiram-mediated inhibition of NF-κb activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines
-
DOI 10.1002/ijc.10972
-
Wang W, McLeod HL, Cassidy J. Disulfiram-mediated inhibition of NF-kappaB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines. Int J Cancer 2003;104:504-11. (Pubitemid 36323923)
-
(2003)
International Journal of Cancer
, vol.104
, Issue.4
, pp. 504-511
-
-
Wang, W.1
McLeod, H.L.2
Cassidy, J.3
-
6
-
-
0035392965
-
Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine- mediated cell death and cell cycle responses
-
Meyers M, Wagner MW, Hwang HS, Kinsella TJ, Boothman DA. Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses. Cancer Res 2001;61:5193-201. (Pubitemid 32681553)
-
(2001)
Cancer Research
, vol.61
, Issue.13
, pp. 5193-5201
-
-
Meyers, M.1
Wagner, M.W.2
Hwang, H.-S.3
Kinsella, T.J.4
Boothman, D.A.5
-
7
-
-
0036570336
-
1 cell fraction is related to 5-fluorouracil cytotoxicity
-
DOI 10.1002/cyto.10087
-
Mirjolet JF, Didelot C, Barberi-Heyob M, Merlin JL. G(1)/S but not G(0)/G(1)cell fraction is related to 5-fluorouracil cytotoxicity. Cytometry 2002;48:6-13. (Pubitemid 34454140)
-
(2002)
Cytometry
, vol.48
, Issue.1
, pp. 6-13
-
-
Mirjolet, J.-F.1
Didelot, C.2
Barberi-Heyob, M.3
Merlin, J.-L.4
-
8
-
-
18444408375
-
COX-2: A molecular target for colorectal cancer prevention
-
DOI 10.1200/JCO.2005.09.051
-
Brown JR, DuBois RN. COX-2: A molecular target for colorectal cancer prevention. J Clin Oncol 2005;23:2840-55. (Pubitemid 46179475)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.12
, pp. 2840-2855
-
-
Brown, J.R.1
DuBois, R.N.2
-
9
-
-
18244401954
-
Cyclooxygenase-2 expression as a new marker for patients with colorectal cancer
-
DOI 10.1007/s10350-004-6120-5
-
Yamauchi T, Watanabe M, Kubota T, Hasegawa H, Ishii Y, Endo T, et al. Cyclooxygenase-2 expression as a new marker for patients with colorectal cancer. Dis Colon Rectum 2002;45:98-103. (Pubitemid 34072758)
-
(2002)
Diseases of the Colon and Rectum
, vol.45
, Issue.1
, pp. 98-103
-
-
Yamauchi, T.1
Watanabe, M.2
Kubota, T.3
Hasegawa, H.4
Ishii, Y.5
Endo, T.6
Kabeshima, Y.7
Yorozuya, K.8
Yamamoto, K.9
Mukai, M.10
Kitajima, M.11
-
10
-
-
0033590207
-
The role of cyclooxygenases in inflammation, cancer, and development
-
Williams CS, Mann M, DuBois RN. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 1999;18:7908-16. (Pubitemid 30066236)
-
(1999)
Oncogene
, vol.18
, Issue.55
, pp. 7908-7916
-
-
Williams, C.S.1
Mann, M.2
DuBois, R.N.3
-
11
-
-
0034471496
-
Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia
-
Fosslien E. Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia. Crit Rev Clin Lab Sci 2000;37:431-502. (Pubitemid 32173442)
-
(2000)
Critical Reviews in Clinical Laboratory Sciences
, vol.37
, Issue.5
, pp. 431-502
-
-
Fosslien, E.1
-
12
-
-
0037307483
-
Cyclooxygenase 2: A molecular target for cancer prevention and treatment
-
DOI 10.1016/S0165-6147(02)00043-3, PII S0165614702000433
-
Subbaramaiah K, Dannenberg AJ. Cyclooxygenase 2: A molecular target for cancer prevention and treatment. Trends Pharmacol Sci 2003;24:96-102. (Pubitemid 36135884)
-
(2003)
Trends in Pharmacological Sciences
, vol.24
, Issue.2
, pp. 96-102
-
-
Subbaramaiah, K.1
Dannenberg, A.J.2
-
13
-
-
0034665122
-
The cyclooxygenase- 2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
-
Jacoby RF, Seibert K, Cole CE, Kelloff G, Lubet RA. The cyclooxygenase- 2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res 2000;60:5040-4.
-
(2000)
Cancer Res
, vol.60
, pp. 5040-5044
-
-
Jacoby, R.F.1
Seibert, K.2
Cole, C.E.3
Kelloff, G.4
Lubet, R.A.5
-
14
-
-
0036896511
-
Synergistic cytotoxicity and apoptosis of JTE-522, a selective cyclooxygenase-2 inhibitor, and 5-fluorotracil against bladder cancer
-
Mizutani Y, Kamoi K, Ukimura O, Kawauchi A, Miki T. Synergistic cytotoxicity and apoptosis of JTE-522, a selective cyclooxygenase-2 inhibitor, and 5-fluorouracil against bladder cancer. J Urol 2002;168:2650-4. (Pubitemid 35402710)
-
(2002)
Journal of Urology
, vol.168
, Issue.6
, pp. 2650-2654
-
-
Mizutani, Y.1
Kamoi, K.2
Ukimura, O.3
Kawauchi, A.4
Miki, T.5
-
15
-
-
2942585284
-
Treatment with 5-fluorouracil and celecoxib displays synergistic regression of ultraviolet light B-induced skin tumors
-
DOI 10.1111/j.0022-202X.2004.22606.x
-
Wilgus TA, Breza TS Jr, Tober KL, Oberyszyn TM. Treatment with 5-fluorouracil and celecoxib displays synergistic regression of ultraviolet light B-induced skin tumors. J Invest Dermatol 2004;122:1488-94. (Pubitemid 38757232)
-
(2004)
Journal of Investigative Dermatology
, vol.122
, Issue.6
, pp. 1488-1494
-
-
Wilgus, T.A.1
Breza Jr., T.S.2
Tober, K.L.3
Oberyszyn, T.M.4
-
16
-
-
36649016713
-
Effect of betulinic acid on anticancer drug-resistant colon cancer cells
-
DOI 10.1111/j.1742-7843.2007.00115.x
-
Jung GR, Kim KJ, Choi CH, Lee TB, Han SI, Han HK, et al. Effect of betulinic acid on anticancer drug-resistant colon cancer cells. Basic Clin Pharmacol Toxicol 2007;101:277-85. (Pubitemid 350194804)
-
(2007)
Basic and Clinical Pharmacology and Toxicology
, vol.101
, Issue.4
, pp. 277-285
-
-
Jung, G.-R.1
Kim, K.-J.2
Choi, C.-H.3
Lee, T.-B.4
Han, S.I.5
Han, H.-K.6
Lim, S.-C.7
-
17
-
-
0023748892
-
Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia
-
Pieters R, Huismans DR, Leyva A, Veerman AJ. Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia. Cancer Lett 1988;41:323-32.
-
(1988)
Cancer Lett
, vol.41
, pp. 323-332
-
-
Pieters, R.1
Huismans, D.R.2
Leyva, A.3
Veerman, A.J.4
-
18
-
-
0020420380
-
Ovarian and plasma prostaglandin E and F levels in brook trout (Salvelinus fontinalis) during pituitary-induced ovulation
-
Cetta F, Goetz FW. Ovarian and plasma prostaglandin E and F levels in brook trout (Salvelinus fontinalis) during pituitary-induced ovulation. Biol Reprod 1982;27:1216-21.
-
(1982)
Biol Reprod
, vol.27
, pp. 1216-1121
-
-
Cetta, F.1
Goetz, F.W.2
-
19
-
-
0035874884
-
c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo
-
Arango D, Corner GA, Wadler S, Catalano PJ, Augenlicht LH. c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo. Cancer Res 2001;61:4910-5. (Pubitemid 32691909)
-
(2001)
Cancer Research
, vol.61
, Issue.12
, pp. 4910-4915
-
-
Arango, D.1
Corner, G.A.2
Wadler, S.3
Catalano, P.J.4
Augenlicht, L.H.5
-
20
-
-
80051914188
-
The synergistic cell killing effects by the transduction of the w-p53 Gene and 5-FU administration in colon cancer cell lines
-
Kim HJ, Lee SC, Lee IK, Kang WK, Oh ST, Chang SK. The synergistic cell killing effects by the transduction of the w-p53 Gene and 5-FU administration in colon cancer cell lines. J Korean Surg Soc 2007;73:481-9.
-
(2007)
J Korean Surg Soc
, vol.73
, pp. 481-489
-
-
Kim, H.J.1
Lee, S.C.2
Lee, I.K.3
Kang, W.K.4
Oh, S.T.5
Chang, S.K.6
-
21
-
-
0030033046
-
Karnes WE Jr. p53 functional loss in a colon cancer cell line with two missense mutations (218leu and 248trp) on separate alleles
-
Rand A, Glenn KS, Alvares CP, White MB, Thibodeau SM, Karnes WE Jr. p53 functional loss in a colon cancer cell line with two missense mutations (218leu and 248trp) on separate alleles. Cancer Lett 1996;98:183-91.
-
(1996)
Cancer Lett
, vol.98
, pp. 183-191
-
-
Rand, A.1
Glenn, K.S.2
Alvares, C.P.3
White, M.B.4
Thibodeau, S.M.5
-
22
-
-
0034685876
-
Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 and p38 mitogen- activated protein kinase pathways
-
DOI 10.1074/jbc.275.20.14838
-
Subbaramaiah K, Hart JC, Norton L, Dannenberg AJ. Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways. J Biol Chem 2000;275:14838-45. (Pubitemid 30337196)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.20
, pp. 14838-14845
-
-
Subbaramaiah, K.1
Hart, J.C.2
Norton, L.3
Dannenberg, A.J.4
-
23
-
-
4944242194
-
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: Analyses of tumor heterogeneity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase (GST)-α, GST-μ, and GST-π
-
DOI 10.1002/cncr.20571
-
Mathieu A, Remmelink M, D'Haene N, Penant S, Gaussin JF, Van Ginckel R, et al. Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: Analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase- 2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione- S-transferase-alpha (GST)-alpha, GST-mu, and GST-pi. Cancer 2004;101:1908-18. (Pubitemid 39328201)
-
(2004)
Cancer
, vol.101
, Issue.8
, pp. 1908-1918
-
-
Mathieu, A.1
Remmelink, M.2
D'Haene, N.3
Penant, S.4
Gaussin, J.-F.5
Van Ginckel, R.6
Darro, F.7
Kiss, R.8
Salmon, I.9
-
24
-
-
21044445750
-
Rapid up-regulation of cyclooxygenase-2 by 5-fluorouracil in human solid tumors
-
DOI 10.1097/00001813-200506000-00004
-
Mercer SJ, Di Nicolantonio F, Knight LA, Gabriel FG, Whitehouse PA, Sharma S, et al. Rapid up-regulation of cyclooxygenase- 2 by 5-fluorouracil in human solid tumors. Anticancer Drugs 2005;16:495-500. (Pubitemid 40685733)
-
(2005)
Anti-Cancer Drugs
, vol.16
, Issue.5
, pp. 495-500
-
-
Mercer, S.J.1
Di Nicolantonio, F.2
Knight, L.A.3
Gabriel, F.G.4
Whitehouse, P.A.5
Sharma, S.6
Fernando, A.7
Bhandari, P.8
Somers, S.S.9
Toh, S.K.10
Cree, I.A.11
-
25
-
-
33748034069
-
Molecular responses of rectal cancer to preoperative chemoradiation
-
DOI 10.1016/j.radonc.2006.07.016, PII S0167814006002970, Papers from ICTR 2006. International Conference on Transtational Research and Pre-Clinical Stratigies in Rediation Oncology
-
Debucquoy A, Goethals L, Geboes K, Roels S, Mc Bride WH, Haustermans K. Molecular responses of rectal cancer to preoperative chemoradiation. Radiother Oncol 2006;80: 172-7. (Pubitemid 44301536)
-
(2006)
Radiotherapy and Oncology
, vol.80
, Issue.2
, pp. 172-177
-
-
Debucquoy, A.1
Goethals, L.2
Geboes, K.3
Roels, S.4
Mc Bride, W.H.5
Haustermans, K.6
-
26
-
-
34547135176
-
Synergistic antitumor effects of celecoxib with 5-fluorouracil depend on IFN-γ
-
DOI 10.1002/ijc.22720
-
Irie T, Tsujii M, Tsuji S, Yoshio T, Ishii S, Shinzaki S, et al. Synergistic antitumor effects of celecoxib with 5-fluorouracil depend on IFN-gamma. Int J Cancer 2007;121:878-83. (Pubitemid 47106220)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.4
, pp. 878-883
-
-
Irie, T.1
Tsujii, M.2
Tsuji, S.3
Yoshio, T.4
Ishii, S.5
Shinzaki, S.6
Egawa, S.7
Kakiuchi, Y.8
Nishida, T.9
Yasumaru, M.10
Iijima, H.11
Murata, H.12
Takehara, T.13
Kawano, S.14
Hayashi, N.15
-
27
-
-
68549104155
-
Co-inhibition of cyclooxygenase-2 and dihydropyrimidine dehydrogenase by non-steroidal anti-inflammatory drugs in tumor cells and xenografts
-
Réti A, Pap E, Zalatnai A, Jeney A, Kralovánszky J, Budai B. Co-inhibition of cyclooxygenase-2 and dihydropyrimidine dehydrogenase by non-steroidal anti-inflammatory drugs in tumor cells and xenografts. Anticancer Res 2009;29:3095-101.
-
(2009)
Anticancer Res
, vol.29
, pp. 3095-3101
-
-
Réti, A.1
Pap, E.2
Zalatnai, A.3
Jeney, A.4
Kralovánszky, J.5
Budai, B.6
-
28
-
-
42549145438
-
Combination therapy of S-1 with selective cyclooxygenase-2 inhibitor for liver metastasis of colorectal carcinoma
-
Tachimori A, Yamada N, Amano R, Ohira M, Hirakawa K. Combination therapy of S-1 with selective cyclooxygenase- 2 inhibitor for liver metastasis of colorectal carcinoma. Anticancer Res 2008;28(2A):629-38. (Pubitemid 351578902)
-
(2008)
Anticancer Research
, vol.28
, Issue.2
, pp. 629-638
-
-
Tachimori, A.1
Yamada, N.2
Amano, R.3
Ohira, M.4
Hirakawa, K.5
-
30
-
-
0347717578
-
2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression
-
DOI 10.1073/pnas.2535911100
-
Chang SH, Liu CH, Conway R, Han DK, Nithipatikom K, Trifan OC, et al. Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression. Proc Natl Acad Sci U S A 2004;101:591-6. (Pubitemid 38084681)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.2
, pp. 591-596
-
-
Chang, S.-H.1
Liu, C.H.2
Conway, R.3
Han, D.K.4
Nithipatikom, K.5
Trifan, O.C.6
Lane, T.F.7
Hla, T.8
-
31
-
-
33747341048
-
Increases in circulating VEGF levels during COX-2 inhibitor treatment in breast cancer patients
-
Ueno T, Chow LW, Toi M. Increases in circulating VEGF levels during COX-2 inhibitor treatment in breast cancer patients. Biomed Pharmacother 2006;60:277-9.
-
(2006)
Biomed Pharmacother
, vol.60
, pp. 277-279
-
-
Ueno, T.1
Chow, L.W.2
Toi, M.3
|