메뉴 건너뛰기




Volumn 16, Issue 4, 2011, Pages 345-352

Microchimerism in promoting graft acceptance in clinical transplantation

Author keywords

clinical organ transplants; donor stem cells; graft acceptance; immune regulation; microchimerism

Indexed keywords

ANTINEOPLASTIC AGENT; BORTEZOMIB; CALCINEURIN INHIBITOR; CYCLOPHOSPHAMIDE; CYCLOSPORIN; FLUDARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; LEUKOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MITOGENIC AGENT; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; RITUXIMAB; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY;

EID: 80051785328     PISSN: 10872418     EISSN: 15317013     Source Type: Journal    
DOI: 10.1097/MOT.0b013e3283489a42     Document Type: Review
Times cited : (7)

References (89)
  • 1
    • 0018612810 scopus 로고
    • Transplantation tolerance across major histocompatibility barriers after total lymphoid irradiation
    • Slavin S, Fuks Z, Strober S, et al. Transplantation tolerance across major histocompatibility barriers after total lymphoid irradiation. Transplantation 1979; 28:359-361. (Pubitemid 10163735)
    • (1979) Transplantation , vol.28 , Issue.5 , pp. 359-361
    • Strober, S.1    Kaplan, H.2    Howard, R.J.3    Sutherland, D.E.R.4
  • 2
    • 0014894053 scopus 로고
    • Studies on heterologous antilymphocyte serum in mice VII: Optimal cellular antigen for induction of immunologic tolerance with antilymphocyte serum
    • Monaco AP, Wood ML. Studies on heterologous antilymphocyte serum in mice. VII: Optimal cellular antigen for induction of immunologic tolerance with antilymphocyte serum. Transplant Proc 1970; 2:489-496.
    • (1970) Transplant Proc , vol.2 , pp. 489-496
    • Monaco, A.P.1    Wood, M.L.2
  • 3
    • 0015591743 scopus 로고
    • Enhanced survival of canine renal allografts of ALS-treated dogs given bone marrow
    • Caridis DT, Liegeois A, Barrett I, Monaco AP. Enhanced survival of canine renal allografts of ALS-treated dogs given bone marrow. Transplant Proc 1973; 5:671-674.
    • (1973) Transplant Proc , vol.5 , pp. 671-674
    • Caridis, D.T.1    Liegeois, A.2    Barrett, I.3    Monaco, A.P.4
  • 4
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • reprint in J Immunol 2010; 184 5-8
    • Billingham RE, Brent L, Medawar PB. Actively acquired tolerance of foreign cells. Nature 1953; 172:603-606; reprint in J Immunol 2010; 184:5-8.
    • (1953) Nature , vol.172 , pp. 603-606
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 5
    • 0018119576 scopus 로고
    • Improvement of kidney-graft survival with increased numbers of blood transfusions
    • Opelz G, Terasaki PI. Improvement of kidney-graft survival with increased numbers of blood transfusions. N Engl J Med 1978; 299:799-803. (Pubitemid 9044523)
    • (1978) New England Journal of Medicine , vol.299 , Issue.15 , pp. 799-803
    • Opelz, G.1    Terasaki, P.I.2
  • 6
    • 0019133898 scopus 로고
    • Deliberate donor-specific blood transfusions prior to living related renal transplantation. A new approach
    • Salvatierra O Jr, Vincenti F, Amend W, et al. Deliberate donor-specific blood transfusions prior to living related renal transplantation: A new approach. Ann Surg 1980; 192:543-552. (Pubitemid 11225438)
    • (1980) Annals of Surgery , vol.192 , Issue.4 , pp. 543-552
    • Salvatierra Jr., O.1    Vincenti, F.2    Amend, W.3
  • 7
    • 0017080404 scopus 로고
    • Possible active enhancement of a human cadaver renal allograft with antilymphocyte serum (ALS) and donor bone marrow: Case report of an initial attempt
    • Monaco AP, Clark AW, Wood ML, et al. Possible active enhancement of a human cadaver renal allograft with antilymphocyte serum (ALS) and donor bone marrow: Case report of an initial attempt. Surgery 1976; 79:384-392.
    • (1976) Surgery , vol.79 , pp. 384-392
    • Monaco, A.P.1    Clark, A.W.2    Wood, M.L.3
  • 8
    • 0026080585 scopus 로고
    • Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients
    • Barber WH, Mankin JA, Laskow DA, et al. Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients. Transplantation 1991; 51:70-75.
    • (1991) Transplantation , vol.51 , pp. 70-75
    • Barber, W.H.1    Mankin, J.A.2    Laskow, D.A.3
  • 24
    • 0032999053 scopus 로고    scopus 로고
    • Simultaneous donor bone marrow and cardiac transplantation: Can tolerance be induced with the development of chimerism?
    • DOI 10.1097/00001573-199903000-00009
    • Gammie JS, Pham SM. Simultaneous donor bone marrow and cardiac transplantation: Can tolerance be induced with the development of chimerism? Curr Opin Cardiol 1999; 14:126-132. (Pubitemid 29141361)
    • (1999) Current Opinion in Cardiology , vol.14 , Issue.2 , pp. 126-132
    • Gammie, J.S.1    Pham, S.M.2
  • 26
    • 0030893515 scopus 로고    scopus 로고
    • Modulatory effects of human donor bone marrow cells on allogeneic cellular immune responses
    • DOI 10.1097/00007890-199703150-00013
    • Mathew JM, Carreno M, Fuller L, et al. Modulatory effects of human donor bone marrow cells on allogeneic cellular immune responses. Transplantation 1997; 63:686-692. (Pubitemid 27132201)
    • (1997) Transplantation , vol.63 , Issue.5 , pp. 686-692
    • Mathew, J.M.1    Carreno, M.2    Fuller, L.3    Ricordi, C.4    Tzakis, A.5    Esquenazi, V.6    Miller, J.7
  • 27
    • 0033610465 scopus 로고    scopus 로고
    • In vitro immunogenicity of cadaver donor bone marrow cells used for the induction of allograft acceptance in clinical transplantation
    • DOI 10.1097/00007890-199910270-00018
    • Mathew JM, Carreno M, Fuller L, et al. In vitro immunogenicity of cadaver donor bone marrow cells used for the induction of allograft acceptance in clinical transplantation. Transplantation 1999; 68:1172-1180. (Pubitemid 29517708)
    • (1999) Transplantation , vol.68 , Issue.8 , pp. 1172-1180
    • Mathew, J.M.1    Carreno, M.2    Fuller, L.3    Ricordi, C.4    Kenyon, N.5    Tzakis, A.G.6    Miller, J.7    Esquenazi, V.8
  • 28
    • 0032522725 scopus 로고    scopus 로고
    • Cellular immune responses of human cadaver donor bone marrow cells and their susceptibility to commonly used immunosuppressive drugs in transplantation
    • DOI 10.1097/00007890-199804150-00015
    • Mathew JM, Carreno M, Zucker K, et al. Cellular immune responses of human cadaver donor bone marrow cells and their susceptibility to commonly used immunosuppressive drugs in transplantation. Transplantation 1998; 65:947-955. (Pubitemid 28201448)
    • (1998) Transplantation , vol.65 , Issue.7 , pp. 947-955
    • Mathew, J.M.1    Carreno, M.2    Zucker, K.3    Fuller, L.4    Kenyon, N.5    Esquenazi, V.6    Ricordi, C.7    Tzakis, A.G.8    Miller, J.9
  • 30
    • 0037183857 scopus 로고    scopus 로고
    • Regulation of alloimmune responses (GvH reactions) in vitro by autologous donor bone marrow cell preparation used in clinical organ transplantation
    • Mathew JM, Carreno M, Fuller L, et al. Regulation of alloimmune responses (GvH reactions) in vitro by autologous donor bone marrow cell preparation used in clinical organ transplantation. Transplantation 2002; 74:846-855.
    • (2002) Transplantation , vol.74 , pp. 846-855
    • Mathew, J.M.1    Carreno, M.2    Fuller, L.3
  • 31
    • 0029075912 scopus 로고
    • Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population
    • Lagoo-Deenadayalan S, Lagoo AS, Lemons JA, et al. Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population. Transpl Immunol 1995; 3:124-134.
    • (1995) Transpl Immunol , vol.3 , pp. 124-134
    • Lagoo-Deenadayalan, S.1    Lagoo, A.S.2    Lemons, J.A.3
  • 32
    • 0032571946 scopus 로고    scopus 로고
    • Tolerance induction by 'megadose' hematopoietic transplants: Donor-type human CD34 stem cells induce potent specific reduction of host antidonor cytotoxic T lymphocyte precursors in mixed lymphocyte culture
    • Rachamim N, Gan J, Segall H, et al. Tolerance induction by 'megadose' hematopoietic transplants: Donor-type human CD34 stem cells induce potent specific reduction of host antidonor cytotoxic T lymphocyte precursors in mixed lymphocyte culture. Transplantation 1998; 65:1386-1393.
    • (1998) Transplantation , vol.65 , pp. 1386-1393
    • Rachamim, N.1    Gan, J.2    Segall, H.3
  • 34
    • 68349137549 scopus 로고    scopus 로고
    • Long-term follow-up of donor chimerism and tolerance after human liver transplantation
    • Ayala R, Grande S, Albizua E, et al. Long-term follow-up of donor chimerism and tolerance after human liver transplantation. Liver Transpl 2009; 15:581-591.
    • (2009) Liver Transpl , vol.15 , pp. 581-591
    • Ayala, R.1    Grande, S.2    Albizua, E.3
  • 36
    • 0032852141 scopus 로고    scopus 로고
    • Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism
    • DOI 10.1097/00007890-199908270-00006
    • Spitzer TR, Delmonico F, Tolkoff-Rubin N, et al. Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism. Transplantation 1999; 68:480-484. (Pubitemid 29416620)
    • (1999) Transplantation , vol.68 , Issue.4 , pp. 480-484
    • Spitzer, T.R.1    Delmonico, F.2    Tolkoff-Rubin, N.3    McAfee, S.4    Sackstein, R.5    Saidman, S.6    Colby, C.7    Sykes, M.8    Sachs, D.H.9    Cosimi, A.B.10
  • 39
    • 78650807243 scopus 로고    scopus 로고
    • Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance
    • LoCascio SA, Morokata T, Chittenden M, et al. Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation 2010; 90:1607-1615.
    • (2010) Transplantation , vol.90 , pp. 1607-1615
    • LoCascio, S.A.1    Morokata, T.2    Chittenden, M.3
  • 41
    • 80051798361 scopus 로고    scopus 로고
    • Inducing tolerance in clinical kidney transplantation [abstract]
    • Strober S, Busque S, Dejbakhsh-Jones S, et al. Inducing tolerance in clinical kidney transplantation [abstract]. Transplantation 2010; 90 (2S):323.
    • (2010) Transplantation , vol.90 , Issue.2 S , pp. 323
    • Strober, S.1    Busque, S.2    Dejbakhsh-Jones, S.3
  • 42
    • 0033669983 scopus 로고    scopus 로고
    • High dose DBMC associated tolerance in liverelated renal allograft recipients
    • Trivedi H, Shah V, Shah P, et al. High dose DBMC associated tolerance in liverelated renal allograft recipients. Transplant Proc 2000; 32:2001-2002.
    • (2000) Transplant Proc , vol.32 , pp. 2001-2002
    • Trivedi, H.1    Shah, V.2    Shah, P.3
  • 43
    • 0037322384 scopus 로고    scopus 로고
    • Mega dose unfractionated donor bone marrow-derived cell infusion in thymus and periphery - An integrated clinical approach for tolerance in living related renal allografts
    • DOI 10.1016/S0041-1345(02)03901-5
    • Trivedi H, Vanikar A, Shah V, et al. Mega dose unfractionated donor bone marrow-derived cell infusion in thymus and periphery: An integrated clinical approach for tolerance in living related renal allografts. Transplant Proc 2003; 35:203-206. (Pubitemid 36194573)
    • (2003) Transplantation Proceedings , vol.35 , Issue.1 , pp. 203-206
    • Trivedi, H.1    Vanikar, A.2    Shah, V.3    Mehta, A.4    Shah, S.5    Shah, T.6    Visana, K.7    Modi, P.8    Sinha, P.9    Trivedi, V.10
  • 44
    • 77954904503 scopus 로고    scopus 로고
    • Clonal deletion with Bortezomib followed by low or no maintenance immunosuppression in renal allograft recipients
    • Trivedi HL, Terasaki PI, Feroz A, et al. Clonal deletion with Bortezomib followed by low or no maintenance immunosuppression in renal allograft recipients. Transplantation 2010; 90:221-222.
    • (2010) Transplantation , vol.90 , pp. 221-222
    • Trivedi, H.L.1    Terasaki, P.I.2    Feroz, A.3
  • 45
    • 80051796936 scopus 로고    scopus 로고
    • Donor specific immunoregulation in HLAidentical renal transplant recipients given Alemtuzimab and donor stem cells
    • Miller J, Leventhal J, Gallon L, et al. Donor specific immunoregulation in HLAidentical renal transplant recipients given Alemtuzimab and donor stem cells. Transplantation 2010; 90:234.
    • (2010) Transplantation , vol.90 , pp. 234
    • Miller, J.1    Leventhal, J.2    Gallon, L.3
  • 46
    • 80051792985 scopus 로고    scopus 로고
    • Induction of donor specific tolerance in recipients of HLA disparate living donor kidney allografts by donor stem cell infusion [abstract 2660]
    • Leventhal J, Gallon L, Miller J, et al. Induction of donor specific tolerance in recipients of HLA disparate living donor kidney allografts by donor stem cell infusion [abstract 2660]. Transplantation 2010; 90:465.
    • (2010) Transplantation , vol.90 , pp. 465
    • Leventhal, J.1    Gallon, L.2    Miller, J.3
  • 47
    • 80051802939 scopus 로고    scopus 로고
    • Facilitating cell enriched stem cell infusion results in durable chimerism, donor specific tolerance, and allows for immunosuppressive drug withdrawal in recipients of HLA disparate living donor kidney allografts [abstract 3375]
    • Leventhal JR, Gallon L, Miller J, et al. Facilitating cell enriched stem cell infusion results in durable chimerism, donor specific tolerance, and allows for immunosuppressive drug withdrawal in recipients of HLA disparate living donor kidney allografts [abstract 3375]. Transplantation 2010; 90:183.
    • (2010) Transplantation , vol.90 , pp. 183
    • Leventhal, J.R.1    Gallon, L.2    Miller, J.3
  • 48
    • 0028006820 scopus 로고
    • Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells
    • Kaufman C, Colson Y, Wren S, et al. Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells. Blood 1994; 84:2436-2446. (Pubitemid 24317373)
    • (1994) Blood , vol.84 , Issue.8 , pp. 2436-2446
    • Kaufman, C.L.1    Colson, Y.L.2    Wren, S.M.3    Watkins, S.4    Simmons, R.L.5    Ildstad, S.T.6
  • 49
    • 80051786876 scopus 로고    scopus 로고
    • Graft engineering (II): A multivariate analysis of the facilitating cell protocol in advanced hematologic malignancy for mismatched donors [abstract]
    • New Orleans LA; 6 December
    • Ildstad ST, Crilley PA, Kaufman CL, et al. Graft engineering (II): A multivariate analysis of the facilitating cell protocol in advanced hematologic malignancy for mismatched donors [abstract]. In: Annual Meeting of the American Society of Hematology; New Orleans, LA; 6 December 1999.
    • (1999) Annual Meeting of the American Society of Hematology
    • Ildstad, S.T.1    Crilley, P.A.2    Kaufman, C.L.3
  • 50
    • 80051800825 scopus 로고    scopus 로고
    • A graft engineering method to allow bone marrow transplantation (BMT) for more highly mismatched recipients with leukemia: Multivariate analysis of a phase I/II protocol [abstract]
    • American Society of Transplant Surgeons and American Society of Transplantation; Chicago, IL; 13-17 May 2000
    • Ildstad ST, Crilley PA, Kaufman CL, et al. A graft engineering method to allow bone marrow transplantation (BMT) for more highly mismatched recipients with leukemia: Multivariate analysis of a phase I/II protocol [abstract]. In: Transplant 2000, American Society of Transplant Surgeons and American Society of Transplantation; Chicago, IL; 13-17 May 2000.
    • (2000) Transplant
    • Ildstad, S.T.1    Crilley, P.A.2    Kaufman, C.L.3
  • 51
    • 80051798583 scopus 로고    scopus 로고
    • Donor marrow infusion in kidney transplantation: Results of preliminary study [abstract]
    • Ravindra K, Herzig R, Paris K, et al. Donor marrow infusion in kidney transplantation: Results of preliminary study [abstract]. Am J Transplant 2008; 8 (Suppl 2):214.
    • (2008) Am J Transplant , vol.8 , Issue.SUPPL. 2 , pp. 214
    • Ravindra, K.1    Herzig, R.2    Paris, K.3
  • 52
    • 0001642095 scopus 로고
    • The use of skin grafting to distinguish between monozygotic and dizygotic twins in cattle
    • Anderson D, Billingham RE, Lampkin GH, Medawar PB. The use of skin grafting to distinguish between monozygotic and dizygotic twins in cattle. Heredity 1952; 6:201-221.
    • (1952) Heredity , vol.6 , pp. 201-221
    • Anderson, D.1    Billingham, R.E.2    Lampkin, G.H.3    Medawar, P.B.4
  • 53
    • 0000658958 scopus 로고
    • Immunogenetic consequences of vascular anastomoses between bovine twins
    • Owen RD. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 1945; 102:400-401.
    • (1945) Science , vol.102 , pp. 400-401
    • Owen, R.D.1
  • 54
    • 33750223517 scopus 로고    scopus 로고
    • Blood group chimerism [review]
    • Drexler C, Wagner T. Blood group chimerism [review]. Curr Opin Hematol 2006; 13:484-489.
    • (2006) Curr Opin Hematol , vol.13 , pp. 484-489
    • Drexler, C.1    Wagner, T.2
  • 56
    • 0028040143 scopus 로고
    • Donor-type microchimerism associated with graft rejection eight years after liver transplantation [7]
    • DOI 10.1056/NEJM199403033300919
    • Schlitt HJ, Hundrieser J, Ringe B, Pichlmayr R. Donor-type microchimerism associated with graft rejection eight years after liver transplantation [letter]. N Engl J Med 1994; 330:646-647. (Pubitemid 24065809)
    • (1994) New England Journal of Medicine , vol.330 , Issue.9 , pp. 646-647
    • Schlitt, H.J.1    Hundrieser, J.2    Ringe, B.3    Pichlmayr, R.4
  • 57
    • 2642708403 scopus 로고    scopus 로고
    • Simultaneous detection of X and Y chromosomes by two-colour fluorescence in situ hybridization in combination with immunophenotyping of single cells to document chimaerism after sex-mismatched bone marrow transplantation
    • van Tol MJ, Langlois van den Bergh R, Mesker W, et al. Simultaneous detection of X and Y chromosomes by two-colour fluorescence in situ hybridization in combination with immunophenotyping of single cells to document chimaerism after sex-mismatched bone marrow transplantation. Bone Marrow Transplant 1998; 21:497-503. (Pubitemid 28107957)
    • (1998) Bone Marrow Transplantation , vol.21 , Issue.5 , pp. 497-503
    • Van Tol, M.1    Langlois Van Den Bergh, R.2    Mesker, W.3    Ouwerkerk-Van Velzen, M.C.M.4    Vossen, J.M.5    Tanke, H.J.6
  • 58
    • 0030848302 scopus 로고    scopus 로고
    • A simultaneous negative and positive selection method that can detect chimerism at a frequency of 1 per 10000 by flow cytometry
    • Pei R, Chen T, Orpilla J, Lee JH. A simultaneous negative and positive selection method that can detect chimerism at a frequency of 1 per 10,000 by flow cytometry. Tissue Antigens 1997; 50:197-201. (Pubitemid 27326286)
    • (1997) Tissue Antigens , vol.50 , Issue.2 , pp. 197-201
    • Pei, R.1    Chen, T.2    Orpilla, J.3    Lee, J.-H.4
  • 61
    • 0033916413 scopus 로고    scopus 로고
    • Microchimerism and rejection: A metaanalysis
    • Sahota A, Gao S, Hayes J, Jindal RM. Microchimerism and rejection: A metaanalysis. Clin Transplant 2000; 14 (4 Pt 1):345-350.
    • (2000) Clin Transplant , vol.14 , Issue.4 PART 1 , pp. 345-350
    • Sahota, A.1    Gao, S.2    Hayes, J.3    Jindal, R.M.4
  • 66
    • 77955363574 scopus 로고    scopus 로고
    • Solid organ transplant-associated acute graft-versus-host disease [review]
    • Zhang Y, Ruiz P. Solid organ transplant-associated acute graft-versus-host disease [review]. Arch Pathol Lab Med 2010; 134:1220-1224.
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 1220-1224
    • Zhang, Y.1    Ruiz, P.2
  • 68
    • 77952884391 scopus 로고    scopus 로고
    • Immune 'tolerance profiles' in donor bone marrow infused kidney transplant patients using multiple ex vivo functional assays
    • This study suggests that patients who have achieved donor-specific unresponsiveness in a cluster analysis combining multiple immune assays are possible candidates for immunosuppression minimization, and such a condition appears to have occurred in many immunosuppressed donor bone marrow cell infused renal transplant recipients
    • Mathew JM, Ciancio G, Burke GW, et al. Immune 'tolerance profiles' in donor bone marrow infused kidney transplant patients using multiple ex vivo functional assays. Hum Immunol 2010; 71:566-576. This study suggests that patients who have achieved donor-specific unresponsiveness in a cluster analysis combining multiple immune assays are possible candidates for immunosuppression minimization, and such a condition appears to have occurred in many immunosuppressed donor bone marrow cell infused renal transplant recipients.
    • (2010) Hum Immunol , vol.71 , pp. 566-576
    • Mathew, J.M.1    Ciancio, G.2    Burke, G.W.3
  • 69
    • 0025021842 scopus 로고
    • Migration patterns of dendritic leukocytes. Implications for transplantation
    • Austyn JM, Larsen CP. Migration patterns of dendritic leukocytes. Implications for transplantation [review]. Transplantation 1990; 49:1-7. (Pubitemid 20051573)
    • (1990) Transplantation , vol.49 , Issue.1 , pp. 1-7
    • Austyn, J.M.1    Larsen, C.P.2
  • 70
    • 0025164132 scopus 로고
    • The role of graft-derived dendritic leukocytes in the rejection of vascularized organ allografts. Recent findings on the migration and function of dendritic leukocytes after transplantation
    • discussion 316-317
    • Larsen CP, Austyn JM, Morris PJ. The role of graft-derived dendritic leukocytes in the rejection of vascularized organ allografts. Recent findings on the migration and function of dendritic leukocytes after transplantation. Ann Surg [review] 1990; 212:308-315; discussion 316-317.
    • (1990) Ann Surg [review] , vol.212 , pp. 308-315
    • Larsen, C.P.1    Austyn, J.M.2    Morris, P.J.3
  • 73
    • 5144225088 scopus 로고    scopus 로고
    • Chimerism and tolerance in transplantation [review]
    • Starzl TE. Chimerism and tolerance in transplantation [review]. Proc Natl Acad Sci U S A 2004; 101 (Suppl 2):14607-14614.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.SUPPL. 2 , pp. 14607-14614
    • Starzl, T.E.1
  • 74
    • 0030924514 scopus 로고    scopus 로고
    • Evidence for the presence of multilineage chimerism and progenitors of donor dendritic cells in the peripheral blood of bone marrow-augmented organ transplant recipients
    • DOI 10.1097/00007890-199709150-00013
    • Rugeles MT, Aitouche A, Zeevi A, et al. Evidence for the presence of multilineage chimerism and progenitors of donor dendritic cells in the peripheral blood of bone marrow-augmented organ transplant recipients. Transplantation 1997; 64:735-741. (Pubitemid 27407102)
    • (1997) Transplantation , vol.64 , Issue.5 , pp. 735-741
    • Rugeles, M.T.1    Aitouche, A.2    Zeevi, A.3    Fung, J.J.4    Watkins, S.C.5    Starzl, T.E.6    Rao, A.S.7
  • 75
    • 77954169111 scopus 로고    scopus 로고
    • Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation
    • Moroso V, Metselaar HJ, Mancham S, et al. Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation. Liver Transpl 2010; 16:895-908.
    • (2010) Liver Transpl , vol.16 , pp. 895-908
    • Moroso, V.1    Metselaar, H.J.2    Mancham, S.3
  • 76
    • 0029072806 scopus 로고
    • Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient
    • Burlingham WJ, Grailer AP, Fechner JH Jr, et al. Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient. Transplantation 1995; 59:1147-1155.
    • (1995) Transplantation , vol.59 , pp. 1147-1155
    • Burlingham, W.J.1    Grailer, A.P.2    Fechner Jr., J.H.3
  • 78
    • 0037565070 scopus 로고    scopus 로고
    • + regulatory T cells do not significantly contribute to direct pathway hyporesponsiveness in stable renal transplant patients
    • DOI 10.1097/01.ASN.0000067411.03024.A9
    • Game DS, Hernandez-Fuentes MP, Chaudhry AN, Lechler RI. CD4+CD25+ regulatory T cells do not significantly contribute to direct pathway hyporesponsiveness in stable renal transplant patients. J Am Soc Nephrol 2003; 14:1652-1661. (Pubitemid 36687069)
    • (2003) Journal of the American Society of Nephrology , vol.14 , Issue.6 , pp. 1652-1661
    • Game, D.S.1    Hernandez-Fuentes, M.P.2    Chaudhry, A.N.3    Lechler, R.I.4
  • 80
    • 50849088989 scopus 로고    scopus 로고
    • Functional analysis of CD4+ CD25bright T cells in kidney transplant patients: Improving suppression of donor-directed responses after transplantation
    • Sewgobind VDKD, van der Laan LJW, Klepper M, et al. Functional analysis of CD4+ CD25bright T cells in kidney transplant patients: Improving suppression of donor-directed responses after transplantation. Clin Transplant 2008; 22:579-586.
    • (2008) Clin Transplant , vol.22 , pp. 579-586
    • Sewgobind, V.D.K.D.1    Van Der Laan, L.J.W.2    Klepper, M.3
  • 82
    • 73349141741 scopus 로고    scopus 로고
    • The human 'Treg MLR': Immune monitoring for FOXP3+ T regulatory cell generation
    • Levitsky J, Miller J, Leventhal J, et al. The human 'Treg MLR': Immune monitoring for FOXP3+ T regulatory cell generation. Transplantation 2009; 88:1303-1311.
    • (2009) Transplantation , vol.88 , pp. 1303-1311
    • Levitsky, J.1    Miller, J.2    Leventhal, J.3
  • 83
    • 85027946292 scopus 로고    scopus 로고
    • Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction
    • Levitsky J, Gallon L, Miller J, et al. Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction. Transplantation 2011; 91:199-206.
    • (2011) Transplantation , vol.91 , pp. 199-206
    • Levitsky, J.1    Gallon, L.2    Miller, J.3
  • 84
    • 33745235090 scopus 로고    scopus 로고
    • Transplant tolerance in non-human primates: Progress, current challenges and unmet needs
    • DOI 10.1111/j.1600-6143.2006.01260.x
    • Kean LS, Gangappa S, Pearson TC, Larsen CP. Transplant tolerance in nonhuman primates: Progress, current challenges and unmet needs [review]. Am J Transplant 2006; 6 (5 Pt 1):884-893. (Pubitemid 44356638)
    • (2006) American Journal of Transplantation , vol.6 , Issue.5 , pp. 884-893
    • Kean, L.S.1    Gangappa, S.2    Pearson, T.C.3    Larsen, C.P.4
  • 85
    • 0028939944 scopus 로고
    • Donor human leukocyte antigens in the circulation of liver allograft recipients
    • Chauhan B, Mathew JM, Shenoy S, et al. Donor human leukocyte antigens in the circulation of liver allograft recipients. Clin Transplant 1995; 9:14-19.
    • (1995) Clin Transplant , vol.9 , pp. 14-19
    • Chauhan, B.1    Mathew, J.M.2    Shenoy, S.3
  • 86
    • 77953209236 scopus 로고    scopus 로고
    • Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans
    • Sagoo P, Perucha E, Sawitzki B, et al. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest 2010; 120:1848-1861.
    • (2010) J Clin Invest , vol.120 , pp. 1848-1861
    • Sagoo, P.1    Perucha, E.2    Sawitzki, B.3
  • 87
    • 77953178765 scopus 로고    scopus 로고
    • Identification of a B cell signature associated with renal transplant tolerance in humans
    • Newell KA, Asare A, Kirk AD, et al. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest 2010; 120:1836-1847.
    • (2010) J Clin Invest , vol.120 , pp. 1836-1847
    • Newell, K.A.1    Asare, A.2    Kirk, A.D.3
  • 88
    • 77955665719 scopus 로고    scopus 로고
    • Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype
    • Pallier A, Hillion S, Danger R, et al. Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype. Kidney Int 2010; 78:503-513.
    • (2010) Kidney Int , vol.78 , pp. 503-513
    • Pallier, A.1    Hillion, S.2    Danger, R.3
  • 89
    • 0034904870 scopus 로고    scopus 로고
    • Immunoregulatory role of chimerism in clinical organ transplantation
    • DOI 10.1038/sj.bmt.1703110
    • Mathew JM, Miller J. Immunoregulatory role of chimerism in clinical organ transplantation. Bone Marrow Transplant 2001; 28:115-119. (Pubitemid 32725711)
    • (2001) Bone Marrow Transplantation , vol.28 , Issue.2 , pp. 115-119
    • Mathew, J.M.1    Miller, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.