Cellular immune responses of human cadaver donor bone marrow cells and their susceptibility to commonly used immunosuppressive drugs in transplantation

Transplantation

Volumn 65, Issue 7, 1998, Pages 947-955

  Mathew, James M ^a   Carreno, Manuel ^a   Zucker, Keith ^a   Fuller, Laphalle ^a   Kenyon, Norma ^a   Esquenazi, Violet ^a   Ricordi, Camillo ^a   Tzakis, Andreas G ^a   Miller, Joshua ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; TACROLIMUS;

ARTICLE; BONE MARROW CELL; CADAVER DONOR; CELL PROLIFERATION; DRUG EFFECT; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; T LYMPHOCYTE;

ANTIGENS, CD34; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CADAVER; CELL DIFFERENTIATION; CELL DIVISION; HUMANS; IMMUNITY, CELLULAR; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE ACTIVATION; T-LYMPHOCYTES; TISSUE DONORS;

EID: 0032522725     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199804150-00015     Document Type: Article

References (30)

1. Billingham RE, Brent L, Medawar PB. "Actively acquired tolerance" of foreign cells. Nature 1953; 172: 603.
2. Opelz G, Terasaki PI. Improvement of kidney-graft survival with increased numbers of blood transfusions. N Engl J Med 1978; 299: 799.
3. Salvatierra O Jr, Vincenti F, Amend W, et al. Deliberate donor-specific blood transfusions prior to living related renal transplantation: a new approach. Ann Surg 1980; 192; 543.
4. Monaco AP, Wood ML. Studies on heterologous antilymphocyte serum in mice. VII. Optimal cellular antigen for induction of immunologic tolerance with ALS. Transplant Proc 1970; 2: 489.
5. Caridis DT, Liegeois A, Barrett I, Monaco AP. Enhanced survival of canine renal allografts of ALS-treated dogs given bone marrow. Transplant Proc 1973; 5: 671.
6. Hartner WC, DeFazio SR, Maki T, Markees TG, Monaco AP, Gozzo JJ. Prolongation of renal allograft survival in antilymphocyte-serum-treated dogs by postoperative injection of density-gradient-fractionated donor bone marrow. Transplantation 1986; 42: 593.
7. Thomas JM, Carver FM, Foil MB. Renal allograft tolerance induced with ATG and donor bone marrow in outbred rhesus monkeys. Transplantation 1983; 36: 104.
8. Thomas JM, Verbanac KM, Thomas FT. The veto mechanism in transplant tolerance. Transplant Rev 1991; 5: 209.
9. Starzl TE, Demetris AJ, Trucco M, et al. Cell migration and chimerism after whole-organ transplantation: the basis of graft acceptance. Hepatology 1993; 17: 1127.
10. Starzl TE, Demetris AJ, Trucco M, et al. Chimerism and donor-specific nonreactivity 27 to 29 years after kidney allotransplantation. Transplantation 1993; 55: 1272.
11. Fontes P, Rau A, Demetris AJ, et al. Augmentation with bone marrow of donor migration for kidney, liver, heart, and pancreas islet transplantation. Lancet 1994; 344: 151.
12. Garcia-Morales R, Carreno M, Mathew JM, et al. The effects of chimeric cells following donor bone marrow infusions as detected by PCR-flow assays in kidney transplant recipients. J Clin Invest 1997; 99: 1118.
13. Ricordi C, Karatzas T, Nery J, et al. High-dose donor bone marrow infusions to enhance allograft survival: the effect of timing. Transplantation 1997; 63: 7.
14. Tsaroucha AK, Ricordi C, Noto TA, et al. Donor peripheral blood stem cell infusions in recipients of living-related liver allografts. Transplantation 1997; 64: 362.
15. Mathew JM, Carreno M, Fuller L, et al. Modulatory effects of human donor bone marrow cells on allogeneic cellular immune responses. Transplantation 1997; 63: 686.
16. Poncelet P, Corayou P. Cytofluorometric quantitation of cell surface antigens by indirect immunofluorescence using monoclonal antibodies. J Immunol Methods 1985; 85: 65.
17. Mathew JM, Shenoy S, Phelan D, Howard T, Mohanakumar T. Biochemical and immunological evaluation of donor specific soluble HLA in the circulation of liver transplant recipients. Transplantation 1996; 62: 217.
18. Venitz J. Pharmacokinetic-pharmacodynamic modeling of reversible drug effects. In: Derendorf H, Hochhaus G, eds. Handbook of pharmacokinetic/pharmacodynamic correlation. Boca Raton, FL: CRC Press, 1995: 6.
19. Dejbakhsh-Jones S, Jerabek L, Weissman IL, Strober S. Extrathymic maturation of alpha beta T cells from hemopoietic stem cells. J Immunol 1995; 155: 3338.
20. Gale RP, Opelz G, Kiuchi OM, Golde DW. Thymus-dependent lymphocytes in human bone marrow. J Clin Invest 1975; 56: 1491.
21. Geha RS, Gatien JG, Parkman R, Crain JD, Rosen FS, Merler E. Discontinuous density gradient analysis of human bone marrow: presence of alloantigen-responsive, PHA-unresponsive cells in normal bone marrow: absence of B lymphocytes in the bone marrow of patients with X-linked agammaglobulinemia. Clin Immunol Immunopathol 1974; 2: 404.
22. Claeson MH, Ropke C. Anti-self suppressive (veto) activity of responder cells in mixed lymphocyte culture. Curr Top Microbiol Immunol 1986; 126: 213.
23. Muraoka S, Miller RG. Cells in bone marrow and in T cell colonies grown from bone marrow can suppress generation of cytotoxic T lymphocytes directed against their self antigens. J Exp Med 1980; 152: 54.
24. Strober S. Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships. Annu Rev Immunol 1984; 1: 219.
25. + bone marrow cells. J Exp Med 1993; 177: 1531.
26. + bone marrow cells. Blood 1994; 84: 1473.
27. Schmitt C, Ktorza S, Sarun S, et al. CD34-positive early stages of human T-cell differentiation. Leuk Lymphoma 1995; 17: 43.
28. - progenitor cells. Blood 1991; 77: 1218.
29. Zucker K, Rosen A, Tsaroucha A, et al. Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings. Transplant Immunol 1997; 5: 225.
30. Pennington LR, Sakamoto K, Popitz-Bergez FA, et al. Bone marrow transplantation in miniature swine. I. Development of the model. Transplantation 1988; 45: 21.