Involvement of multiple subpopulations of human bone marrow cells in the regulation of allogeneic cellular immune responses

Transplantation

Volumn 70, Issue 12, 2000, Pages 1752-1760

  Mathew, James M ^a   Fuller, Laphalle ^a   Carreno, Manuel ^a   Garcia Morales, Rolando ^a   Burke III, George W ^a   Ricordi, Camillo ^a   Esquenazi, Violet ^a,b   Tzakis, Andreas G ^a   Miller, Joshua ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; CD15 ANTIGEN; CD19 ANTIGEN; CD2 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD4 ANTIGEN; CD5 ANTIGEN; GLYCOPHORIN A; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CADAVER DONOR; CELL LINEAGE; CELL MEDIATED LYMPHOLYSIS; CELL SUBPOPULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; MIXED LYMPHOCYTE REACTION; PRIORITY JOURNAL; PROLYMPHOCYTE; PROMYELOCYTE; SPLEEN CELL; T LYMPHOCYTE SUBPOPULATION;

EID: 0034722931     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200012270-00015     Document Type: Article

References (37)

1. Studies on heterologous antilymphocyte serum in mice: VII. Optimal cellular antigen for induction of immunologic tolerance with ALS
2. Enhanced survival of canine renal allografts of ALS-treated dogs given bone marrow
3. Prolongation of renal allograft survival in antilymphocyte-serum-treated dogs by postoperative injection of density-gradient-fractionated donor bone marrow
4. Improvement of kidney-graft survival with increased numbers of blood transfusions
5. Deliberate donor-specific blood transfusions prior to living related renal transplantation
6. Mixed allogeneic chimerism as an approach to transplantation tolerance
7. Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients
8. Bone marrow augmentation of donor-cell chimerism in kidney, liver, heart, and pancreas islet transplantation
9. Cell migration and chimerism after whole organ transplantation: The basis of graft acceptance
10. Chimerism and donor specific nonreactivity 27 to 29 years after kidney allotrasplantation
11. Multiple bone marrow infusions to enhance acceptance of allografts from the same donor
12. High-dose donor bone marrow infusions to enhance allograft survival: The effect of timing
13. The effects of chimeric cells following donor bone marrow infusions as detected by PCR-flow assays in kidney transplant recipients
14. Continuing observations on the regulatory effects of donor-specific bone marrow cell infusions and chimerism in kidney transplant recipients
15. Cellular immune responses of human cadaver donor bone marrow cells and their susceptibility to commonly used immunosuppressive drugs in transplantation
16. In vitro immunogenicity of cadaver donor bone marrow cells used for the induction of allograft acceptance in clinical transplantation
17. Modulatory effects of human donor bone marrow cells on allogeneic cellular immune responses
18. Immunoregulation of bone marrow infused LRD renal transplant recipients by chimeric cells of donor phenotype
19. The human bone marrow as an immunoregulatory organ
20. Peripheral blood microchimerism in human liver and renal transplant recipients: Rejection despite donor-specific chimerism
21. Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient
22. Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population
23. Tolerance induction by megadose of hematopoietic transplants: Donor-type human CD34 stem cells induce potent specific reduction of host anti-donor cytotoxic T lymphocyte precursors in mixed lymphocyte culture
24. An immunological suppressor cell which inactivates cytotoxic T lymphocyte precursor cells recognizing it
25. The veto mechanism in transplant tolerance
26. Mouse skin graft prolongation with donor strain bone marrow and anti-lymphocyte serum: Surface markers of the active bone marrow cells
27. Phenotypic characterization of the novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells
28. In vitro and in vivo analysis of bone marrow-derived CD3+, CD4-, CD8-, NK1.1 + cell lines
29. Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease
30. +) T cells which promote tolerance induction and regulate autoimmunity
31. Alloantigen-induced human lymphocytes rendered nonresponsive by a combination of anti-CD80 monoclonal antibodies and cyclosporin-A suppress mixed lymphocyte reaction in vitro
32. Regulation of mouse immuno-responses by a natural suppressor cell clone from bone marrow
33. + lymphocytes, and cells that also co-express CD8 by IL-2, IL-12 and anti-CD3 monoclonal antibody
34. -) prolong cardiac allograft survival in non-immuno-suppressed recipients
35. Monocyte-derived dendritic cell precursors facilitate tolerance to heart allografts after total lymphoid irradiation
36. Characterization of natural suppressor cells in human bone marrow
37. CD20 (pan-B cell antigen) expression on bone marrow derived T cells