Asymmetric synthesis of isothiazoles through Cu catalysis: Direct catalytic asymmetric conjugate addition of allyl cyanide to α,β-unsaturated thioamides

Angewandte Chemie - International Edition

Volumn 50, Issue 34, 2011, Pages 7910-7914

  Yanagida, Yuka ^a,b   Yazaki, Ryo ^a,b   Kumagai, Naoya ^a   Shibasaki, Masakatsu ^a  

^a INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

allyl cyanides; asymmetric catalysis; cyclization; homogeneous catalysis; isothiazoles

Indexed keywords

ALLYL CYANIDES; ASYMMETRIC CATALYSIS; ASYMMETRIC CONJUGATE ADDITION; ASYMMETRIC SYNTHESIS; CU CATALYSIS; CU-BASED; ELECTROPHILES; ENANTIO; HOMOGENEOUS CATALYSIS; INTRAMOLECULAR CYCLIZATIONS; ISOTHIAZOLES; LEWIS ACID; THIOAMIDES;

CATALYSIS; CATALYSTS; CYANIDES; REACTION KINETICS;

CYCLIZATION;

ALLYL CYANIDE; COPPER; NITRILE; THIAZOLE DERIVATIVE; THIOAMIDE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; STEREOISOMERISM; SYNTHESIS;

CATALYSIS; CHEMISTRY TECHNIQUES, SYNTHETIC; COPPER; CYCLIZATION; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NITRILES; STEREOISOMERISM; THIAZOLES; THIOAMIDES;

EID: 80051777084     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201102467     Document Type: Article

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