3-Benzisothiazolylpiperazine derivatives as potential atypical antipsychotic agents

Journal of Medicinal Chemistry

Volumn 39, Issue 1, 1996, Pages 143-148

  Howard, Harry R ^a   Lowe III, John A ^a   Seeger, Thomas F ^a   Seymour, Patricia A ^a   Zorn, Stevin H ^a   Maloney, Patrick R ^a   Ewing, Frank E ^a   Newman, Michael E ^a   Schmidt, Anne W ^a   Furman, Jerome S ^a   Robinson, Gwendolyn L ^a   Jackson, Elisa ^a   Johnson, Celeste ^a   Morrone, Jean ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOMORPHINE; CLOZAPINE; DEXAMPHETAMINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; INOSITOL PHOSPHATE; KETANSERIN; NEUROLEPTIC AGENT; OLANZAPINE; PIPERAZINE DERIVATIVE; PRAZOSIN; RISPERIDONE; SEROTONIN 2A RECEPTOR; SPIPERONE; TIOSPIRONE; ZIPRASIDONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN HOMOGENATE; BRAIN SLICE; CATALEPSY; CONTROLLED STUDY; DRUG EFFICACY; DRUG RECEPTOR BINDING; EXTRAPYRAMIDAL SYMPTOM; LOCOMOTION; NONHUMAN; ORAL DRUG ADMINISTRATION; PHOSPHOINOSITIDE METABOLISM; PSYCHOSIS; RAT; RECEPTOR AFFINITY; SCHIZOPHRENIA; STEREOTYPY; SUBCUTANEOUS DRUG ADMINISTRATION;

AMPHETAMINE; ANIMALS; ANTIPSYCHOTIC AGENTS; APOMORPHINE; AVOIDANCE LEARNING; BRAIN; CATALEPSY; CLOZAPINE; DOPAMINE; DRUG DESIGN; HUMANS; MOLECULAR STRUCTURE; PHOSPHATIDYLINOSITOLS; PIPERAZINES; PRAZOSIN; RATS; RECEPTORS, ADRENERGIC; RECEPTORS, DOPAMINE; SEROTONIN ANTAGONISTS; THIAZOLES;

EID: 13344283414     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950625l     Document Type: Article

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