Permeation through the cell membrane of a boron-based β-lactamase inhibitor

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Minozzi, Manuela ^a   Lattanzi, Gianluca ^b   Benz, Roland ^c   Costi, Maria P ^d   Venturelli, Alberto ^d   Carloni, Paolo ^e  

^a ROMA TRE UNIVERSITY   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c JACOBS UNIVERSITY BREMEN   (Germany)

^d UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^e RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINOMETHYL BENZO[B]THIOPHENE 2 BORONIC ACID; BENZO[B]THIOPHENE 2 BORONIC ACID DERIVATIVE; BETA LACTAMASE; BETA LACTAMASE INHIBITOR; BORON; OUTER MEMBRANE PROTEIN F; PHLORETIN; PORIN; UNCLASSIFIED DRUG; 1-PALMITOYL-2-OLEOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; BACTERIAL PROTEIN; BENZO(B)THIOPHENE 2 BORONIC ACID; BENZO(B)THIOPHENE-2-BORONIC ACID; BORONIC ACID DERIVATIVE; ENZYME INHIBITOR; PHOSPHATIDYLCHOLINE; THIOPHENE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; DIPOLE; DRUG PENETRATION; ELECTROPHYSIOLOGY; GRAM NEGATIVE BACTERIUM; HYDROGEN BOND; HYDROPHILICITY; LIPID BILAYER; LIPOPHILICITY; MEMBRANE CONDUCTANCE; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; NONHUMAN; PH; ANTIBIOTIC RESISTANCE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; KINETICS; METABOLISM; PHYSIOLOGY;

NEGIBACTERIA;

BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; BORONIC ACIDS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; COMPUTER SIMULATION; DRUG DESIGN; ELECTROPHYSIOLOGY; ENZYME INHIBITORS; GRAM-NEGATIVE BACTERIA; KINETICS; LIPID BILAYERS; MOLECULAR STRUCTURE; PHOSPHATIDYLCHOLINES; THIOPHENES;

EID: 80051756889     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023187     Document Type: Article

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