Behaviour of small solutes and large drugs in a lipid bilayer from computer simulations

Biochimica et Biophysica Acta - Biomembranes

Volumn 1718, Issue 1-2, 2005, Pages 1-21

  Bemporad, D ^a   Luttmann, C ^b   Essex, J W ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SANOFI   (France)

Author keywords

blockers; Constraint; DPPC membrane; Molecular dynamics simulation; Permeability

Indexed keywords

ACETIC ACID; ALPRENOLOL; ATENOLOL; DRUG; LIPID; PINDOLOL; WATER;

ARTICLE; COMPUTER MODEL; COMPUTER SIMULATION; CONFORMATION; DRUG ABSORPTION; DRUG DESIGN; ENTROPY; HYDRATION; HYDROGEN BOND; HYDROPHOBICITY; LIPID BILAYER; MEMBRANE; MOLECULAR DYNAMICS; PARAMETER; PREDICTION; PRIORITY JOURNAL; SOLUTE; STRUCTURE ANALYSIS; TIME;

ADRENERGIC BETA-ANTAGONISTS; CELL MEMBRANE PERMEABILITY; COMPUTER SIMULATION; DRUG CARRIERS; DRUG DESIGN; HYDROGEN BONDING; LIPID BILAYERS; SOLUTIONS;

EID: 28144454423     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2005.07.009     Document Type: Article

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