Desmosterol replaces cholesterol for ligand binding function of the serotonin 1A receptor in solubilized hippocampal membranes: Support for nonannular binding sites for cholesterol?

Biochimica et Biophysica Acta - Biomembranes

Volumn 1808, Issue 10, 2011, Pages 2428-2434

  Singh, Pushpendra ^a   Jafurulla, Md ^a   Paila, Yamuna Devi ^a   Chattopadhyay, Amitabha ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

Cholesterol; Desmosterol; Fluorescence anisotropy; Ligand binding function; Nonannular binding site; Serotonin 1A receptor

Indexed keywords

3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; CHOLESTEROL; DESMOSTEROL; G PROTEIN COUPLED RECEPTOR; METHYL BETA CYCLODEXTRIN; SEROTONIN 1A RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CHEMICAL BOND; CONTROLLED STUDY; HIPPOCAMPUS; LIGAND BINDING; LIPID MEMBRANE; MEMBRANE BINDING; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PURIFICATION; RECEPTOR BINDING; RECEPTOR SOLUBILIZATION; SEROTONINERGIC SYSTEM; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; CATTLE; CELL MEMBRANE; CHOLESTEROL; DESMOSTEROL; FLUORESCENCE POLARIZATION; HIPPOCAMPUS; LIGANDS; RADIOLIGAND ASSAY; RECEPTOR, SEROTONIN, 5-HT1A; SOLUBILITY;

EID: 80051728697     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.06.022     Document Type: Article

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