-
1
-
-
38149070791
-
Nuclear FAK promotes cell proliferation and survival through FERMenhanced p53 degradation
-
Lim, S.T.; Chen, X.L.; Lim, Y.; Hanson, D.A.; Vo, T.T.; Howerton, K.; Larocque, N.; Fisher, S.J.; Schlaepfer, D.D.; Ilic, D. Nuclear FAK promotes cell proliferation and survival through FERMenhanced p53 degradation. Mol. Cell, 2008, 29, 9-22.
-
(2008)
Mol. Cell
, vol.29
, pp. 9-22
-
-
Lim, S.T.1
Chen, X.L.2
Lim, Y.3
Hanson, D.A.4
Vo, T.T.5
Howerton, K.6
Larocque, N.7
Fisher, S.J.8
Schlaepfer, D.D.9
Ilic, D.10
-
2
-
-
21644466387
-
Direct interaction of the N-terminal domain of focal adhesion kinase with the Nterminal transactivation domain of p53
-
Golubovskaya, V.M.; Finch, R.; Cance, W.G. Direct interaction of the N-terminal domain of focal adhesion kinase with the Nterminal transactivation domain of p53. J. Biol. Chem., 2005, 280, 25008-25021.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 25008-25021
-
-
Golubovskaya, V.M.1
Finch, R.2
Cance, W.G.3
-
3
-
-
69849090245
-
Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2
-
Luo, S.W.; Zhang, C.; Zhang, B.; Kim, C.H.; Qiu, Y.Z.; Du, Q.S.; Mei, L.; Xiong, W.C. Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2. EMBO J., 2009, 28, 2568-2582.
-
(2009)
EMBO J
, vol.28
, pp. 2568-2582
-
-
Luo, S.W.1
Zhang, C.2
Zhang, B.3
Kim, C.H.4
Qiu, Y.Z.5
Du, Q.S.6
Mei, L.7
Xiong, W.C.8
-
4
-
-
0035661624
-
Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression
-
Zhao, J.; Pestell, R.; Guan, J.L. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression. Mol. Biol. Cell, 2001, 12, 4066-4077.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 4066-4077
-
-
Zhao, J.1
Pestell, R.2
Guan, J.L.3
-
5
-
-
0038433306
-
Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression
-
Zhao, J.; Bian, Z.C.; Yee, K.; Chen, B.P.; Chien, S.; Guan, J.L. Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression. Mol. Cell, 2003, 11, 1503-1515.
-
(2003)
Mol. Cell
, vol.11
, pp. 1503-1515
-
-
Zhao, J.1
Bian, Z.C.2
Yee, K.3
Chen, B.P.4
Chien, S.5
Guan, J.L.6
-
6
-
-
33748068089
-
New concepts regarding focal adhesion kinase promotion of cell migration and proliferation
-
Cox, B.D.; Natarajan, M.; Stettner, M.R.; Gladson, C.L. New concepts regarding focal adhesion kinase promotion of cell migration and proliferation. J. Cell Biochem., 2006, 99, 35-52.
-
(2006)
J. Cell Biochem
, vol.99
, pp. 35-52
-
-
Cox, B.D.1
Natarajan, M.2
Stettner, M.R.3
Gladson, C.L.4
-
7
-
-
34548085454
-
Focal adhesion kinase and p53 signaling in cancer cells
-
Golubovskaya, V.M.; Cance, W.G. Focal adhesion kinase and p53 signaling in cancer cells. Int. Rev. Cytol., 2007, 263, 103-153.
-
(2007)
Int. Rev. Cytol
, vol.263
, pp. 103-153
-
-
Golubovskaya, V.M.1
Cance, W.G.2
-
8
-
-
77956626576
-
Focal adhesion kinase and p53 signal transduction pathways in cancer
-
Golubovskaya, V.M.; Cance, W. Focal adhesion kinase and p53 signal transduction pathways in cancer. Front Biosci., 2010, 15, 901-912.
-
(2010)
Front Biosci
, vol.15
, pp. 901-912
-
-
Golubovskaya, V.M.1
Cance, W.2
-
9
-
-
55349105491
-
Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer
-
Provenzano, P.P.; Inman, D.R.; Eliceiri, K.W.; Beggs, H.E.; Keely, P.J. Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am. J. Pathol., 2008, 173, 1551-1565.
-
(2008)
Am. J. Pathol
, vol.173
, pp. 1551-1565
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Beggs, H.E.4
Keely, P.J.5
-
10
-
-
69349085098
-
The direct effect of focal adhesion kinase (FAK), dominantnegative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis
-
Golubovskaya, V.M.; Zheng, M.; Zhang, L.; Li, J.L.; Cance, W.G. The direct effect of focal adhesion kinase (FAK), dominantnegative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis. BMC Cancer, 2009, 9, 280.
-
(2009)
BMC Cancer
, vol.9
, pp. 280
-
-
Golubovskaya, V.M.1
Zheng, M.2
Zhang, L.3
Li, J.L.4
Cance, W.G.5
-
11
-
-
79952752679
-
Evolving therapies and FAK inhibitors for the treatment of cancer
-
Dunn, K.B.; Heffler, M.; Golubovskaya, V.M. Evolving therapies and FAK inhibitors for the treatment of cancer. Anticancer Agents Med. Chem., 2010, 10, 722-734.
-
(2010)
Anticancer Agents Med. Chem
, vol.10
, pp. 722-734
-
-
Dunn, K.B.1
Heffler, M.2
Golubovskaya, V.M.3
-
12
-
-
0036230877
-
DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis
-
Cohen, E.D.; Mariol, M.C.; Wallace, R.M.; Weyers, J.; Kamberov, Y.G.; Pradel, J.; Wilder, E.L. DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis. Dev Cell, 2002, 2, 437-448.
-
(2002)
Dev Cell
, vol.2
, pp. 437-448
-
-
Cohen, E.D.1
Mariol, M.C.2
Wallace, R.M.3
Weyers, J.4
Kamberov, Y.G.5
Pradel, J.6
Wilder, E.L.7
-
13
-
-
79959892925
-
Focal Adhesion Kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate
-
Fonar, Y.; Gutkovich, Y.E.; Root, H.; Malyarova, A.; Aamar, E.; Golubovskaya, V.M.; Elias, S.; Elkouby, Y.M.; Frank, D. Focal Adhesion Kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate. Mol Biol Cell, 2011, 22, 2409-2421.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 2409-2421
-
-
Fonar, Y.1
Gutkovich, Y.E.2
Root, H.3
Malyarova, A.4
Aamar, E.5
Golubovskaya, V.M.6
Elias, S.7
Elkouby, Y.M.8
Frank, D.9
-
14
-
-
77951226494
-
Mesodermal Wnt signaling organizes the neural plate via Meis3
-
Elkouby, Y.M.; Elias, S.; Casey, E.S.; Blythe, S.A.; Tsabar, N.; Klein, P.S.; Root, H.; Liu, K.J.; Frank, D. Mesodermal Wnt signaling organizes the neural plate via Meis3. Development, 2010, 137, 1531-1541.
-
(2010)
Development
, vol.137
, pp. 1531-1541
-
-
Elkouby, Y.M.1
Elias, S.2
Casey, E.S.3
Blythe, S.A.4
Tsabar, N.5
Klein, P.S.6
Root, H.7
Liu, K.J.8
Frank, D.9
-
15
-
-
73149114381
-
Early activation of the betacatenin pathway in osteocytes is mediated by nitric oxide, phosphatidyl inositol-3 kinase/Akt, and focal adhesion kinase
-
Santos, A.; Bakker, A.D.; Zandieh-Doulabi, B.; de Blieck- Hogervorst, J.M.; Klein-Nulend, J. Early activation of the betacatenin pathway in osteocytes is mediated by nitric oxide, phosphatidyl inositol-3 kinase/Akt, and focal adhesion kinase. Biochem Biophys Res Commun, 2010, 391, 364-369.
-
(2010)
Biochem Biophys Res Commun
, vol.391
, pp. 364-369
-
-
Santos, A.1
Bakker, A.D.2
Zandieh-Doulabi, B.3
de Blieck, H.J.M.4
Klein-Nulend, J.5
-
16
-
-
77957155478
-
Antagonistic interplay between mechanical forces and glucocorticoids in bone: A tale of kinases
-
Bellido, T. Antagonistic interplay between mechanical forces and glucocorticoids in bone: a tale of kinases. J Cell Biochem, 2010, 111, 1-6.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1-6
-
-
Bellido, T.1
-
17
-
-
40849106249
-
Osteocytes, mechanosensing and Wnt signaling
-
Bonewald, L.F.; Johnson, M.L. Osteocytes, mechanosensing and Wnt signaling. Bone, 2008, 42, 606-615.
-
(2008)
Bone
, vol.42
, pp. 606-615
-
-
Bonewald, L.F.1
Johnson, M.L.2
-
18
-
-
57649237947
-
Betacatenin levels influence rapid mechanical responses in osteoblasts
-
Case, N.; Ma, M.; Sen, B.; Xie, Z.; Gross, T.S.; Rubin, J. Betacatenin levels influence rapid mechanical responses in osteoblasts. J Biol Chem, 2008, 283, 29196-29205.
-
(2008)
J Biol Chem
, vol.283
, pp. 29196-29205
-
-
Case, N.1
Ma, M.2
Sen, B.3
Xie, Z.4
Gross, T.S.5
Rubin, J.6
-
19
-
-
11944250954
-
Fluid shear stress induces beta-catenin signaling in osteoblasts
-
Norvell, S.M.; Alvarez, M.; Bidwell, J.P.; Pavalko, F.M. Fluid shear stress induces beta-catenin signaling in osteoblasts. Calcif. Tissue Int., 2004, 75, 396-404.
-
(2004)
Calcif. Tissue Int
, vol.75
, pp. 396-404
-
-
Norvell, S.M.1
Alvarez, M.2
Bidwell, J.P.3
Pavalko, F.M.4
-
20
-
-
33846026749
-
Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone
-
Robinson, J.A.; Chatterjee-Kishore, M.; Yaworsky, P.J.; Cullen, D.M.; Zhao, W.; Li, C.; Kharode, Y.; Sauter, L.; Babij, P.; Brown, E.L.; Hill, A.A.; Akhter, M.P.; Johnson, M.L.; Recker, R.R.; Komm, B.S.; Bex, F.J. Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone. J. Biol. Chem., 2006, 281, 31720-31728.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 31720-31728
-
-
Robinson, J.A.1
Chatterjee-Kishore, M.2
Yaworsky, P.J.3
Cullen, D.M.4
Zhao, W.5
Li, C.6
Kharode, Y.7
Sauter, L.8
Babij, P.9
Brown, E.L.10
Hill, A.A.11
Akhter, M.P.12
Johnson, M.L.13
Recker, R.R.14
Komm, B.S.15
Bex, F.J.16
-
21
-
-
70349216501
-
Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes
-
Santos, A.; Bakker, A.D.; Zandieh-Doulabi, B.; Semeins, C.M.; Klein-Nulend, J. Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes. J Orthop Res, 2009, 27, 1280-1287.
-
(2009)
J Orthop Res
, vol.27
, pp. 1280-1287
-
-
Santos, A.1
Bakker, A.D.2
Zandieh-Doulabi, B.3
Semeins, C.M.4
Klein-Nulend, J.5
-
22
-
-
23944499058
-
Mechanical stimulation prevents osteocyte apoptosis: Requirement of integrins, Src kinases, and ERKs
-
Plotkin, L.I.; Mathov, I.; Aguirre, J.I.; Parfitt, A.M.; Manolagas, S.C.; Bellido, T. Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs. Am. J. Physiol. Cell Physiol., 2005, 289, C633-643.
-
(2005)
Am. J. Physiol. Cell Physiol
, vol.289
-
-
Plotkin, L.I.1
Mathov, I.2
Aguirre, J.I.3
Parfitt, A.M.4
Manolagas, S.C.5
Bellido, T.6
-
23
-
-
77957166970
-
Kinase activation and osteocyte survival promoted by mechanical stimulation require LRP5/6 signaling and β-catenin accumulation, but not β-catenin/TCF-dependent transcription
-
(Abstr.)
-
Martin-Millan MPL., Vyas K, Frera G, Gortazar AR, Almeida M, Manolagas SC, Bellido T. Kinase activation and osteocyte survival promoted by mechanical stimulation require LRP5/6 signaling and β-catenin accumulation, but not β-catenin/TCF-dependent transcription. J. Bone Min. Res., 2008, 23:S400. (Abstr.).
-
(2008)
J. Bone Min. Res
, vol.23
-
-
Martin-Millan, M.P.L.1
Vyas, K.2
Frera, G.3
Gortazar, A.R.4
Almeida, M.5
Manolagas, S.C.6
Bellido, T.7
-
24
-
-
77955587900
-
Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling
-
Ashton, G.H.; Morton, J.P.; Myant, K.; Phesse, T.J.; Ridgway, R.A.; Marsh, V.; Wilkins, J.A.; Athineos, D.; Muncan, V.; Kemp, R.; Neufeld, K.; Clevers, H.; Brunton, V.; Winton, D.J.; Wang, X.; Sears, R.C.; Clarke, A.R.; Frame, M.C.; Sansom, O.J. Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling. Dev. Cell, 2010, 19, 259-269.
-
(2010)
Dev. Cell
, vol.19
, pp. 259-269
-
-
Ashton, G.H.1
Morton, J.P.2
Myant, K.3
Phesse, T.J.4
Ridgway, R.A.5
Marsh, V.6
Wilkins, J.A.7
Athineos, D.8
Muncan, V.9
Kemp, R.10
Neufeld, K.11
Clevers, H.12
Brunton, V.13
Winton, D.J.14
Wang, X.15
Sears, R.C.16
Clarke, A.R.17
Frame, M.C.18
Sansom, O.J.19
-
25
-
-
33645022769
-
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
-
Natarajan, M.; Stewart, J.E.; Golemis, E.A.; Pugacheva, E.N.; Alexandropoulos, K.; Cox, B.D.; Wang, W.; Grammer, J.R.; Gladson, C.L. HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene, 2006, 25, 1721-1732.
-
(2006)
Oncogene
, vol.25
, pp. 1721-1732
-
-
Natarajan, M.1
Stewart, J.E.2
Golemis, E.A.3
Pugacheva, E.N.4
Alexandropoulos, K.5
Cox, B.D.6
Wang, W.7
Grammer, J.R.8
Gladson, C.L.9
-
26
-
-
79958244521
-
HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression
-
Li, Y.; Bavarva, J.H.; Wang, Z.; Guo, J.; Qian, C.; Thibodeau, S.N.; Golemis, E.A.; Liu, W. HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression. Oncogene, 2011.
-
(2011)
Oncogene
-
-
Li, Y.1
Bavarva, J.H.2
Wang, Z.3
Guo, J.4
Qian, C.5
Thibodeau, S.N.6
Golemis, E.A.7
Liu, W.8
-
27
-
-
2442583529
-
Cloning and characterization of the promoter region of human focal adhesion kinase gene: Nuclear factor kappa B and p53 binding sites
-
Golubovskaya, V.; Kaur, A.; Cance, W. Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites. Biochim. Biophys. Acta, 2004, 1678, 111-125.
-
(2004)
Biochim. Biophys. Acta
, vol.1678
, pp. 111-125
-
-
Golubovskaya, V.1
Kaur, A.2
Cance, W.3
-
28
-
-
78649633119
-
P53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines
-
Anaganti, S.; Fernandez-Cuesta, L.; Langerod, A.; Hainaut, P.; Olivier, M. p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines. Cancer Lett, 2011, 300, 215-224.
-
(2011)
Cancer Lett
, vol.300
, pp. 215-224
-
-
Anaganti, S.1
Fernandez-Cuesta, L.2
Langerod, A.3
Hainaut, P.4
Olivier, M.5
-
29
-
-
0036484916
-
Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45
-
Katoh, M. Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45. Int. J. Oncol., 2002, 20, 373-377.
-
(2002)
Int. J. Oncol
, vol.20
, pp. 373-377
-
-
Katoh, M.1
-
30
-
-
77950128955
-
Masitinib combined with standard gemcitabine chemotherapy: In vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model
-
Humbert, M.; Casteran, N.; Letard, S.; Hanssens, K.; Iovanna, J.; Finetti, P.; Bertucci, F.; Bader, T.; Mansfield, C.D.; Moussy, A.; Hermine, O.; Dubreuil, P. Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model. PLoS One, 2010, 5, e9430.
-
(2010)
PLoS One
, vol.e9430
, pp. 5
-
-
Humbert, M.1
Casteran, N.2
Letard, S.3
Hanssens, K.4
Iovanna, J.5
Finetti, P.6
Bertucci, F.7
Bader, T.8
Mansfield, C.D.9
Moussy, A.10
Hermine, O.11
Dubreuil, P.12
-
31
-
-
0242493171
-
RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity
-
Duxbury, M.S.; Ito, H.; Benoit, E.; Zinner, M.J.; Ashley, S.W.; Whang, E.E. RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem. Biophys. Res. Commun., 2003, 311, 786-792.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.311
, pp. 786-792
-
-
Duxbury, M.S.1
Ito, H.2
Benoit, E.3
Zinner, M.J.4
Ashley, S.W.5
Whang, E.E.6
-
32
-
-
70349658639
-
Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT
-
Dubreuil, P.; Letard, S.; Ciufolini, M.; Gros, L.; Humbert, M.; Casteran, N.; Borge, L.; Hajem, B.; Lermet, A.; Sippl, W.; Voisset, E.; Arock, M.; Auclair, C.; Leventhal, P.S.; Mansfield, C.D.; Moussy, A.; Hermine, O. Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT. PLoS One, 2009, 4, e7258.
-
(2009)
PLoS One
, vol.4
-
-
Dubreuil, P.1
Letard, S.2
Ciufolini, M.3
Gros, L.4
Humbert, M.5
Casteran, N.6
Borge, L.7
Hajem, B.8
Lermet, A.9
Sippl, W.10
Voisset, E.11
Arock, M.12
Auclair, C.13
Leventhal, P.S.14
Mansfield, C.D.15
Moussy, A.16
Hermine, O.17
-
33
-
-
45849093670
-
The what, where, when and how of Wnt/betacatenin signaling in pancreas development
-
Murtaugh, L.C. The what, where, when and how of Wnt/betacatenin signaling in pancreas development. Organogenesis, 2008, 4, 81-86.
-
(2008)
Organogenesis
, vol.4
, pp. 81-86
-
-
Murtaugh, L.C.1
-
34
-
-
70649105588
-
Integration of the beta-catenindependent Wnt pathway with integrin signaling through the adaptor molecule Grb2
-
Crampton, S.P.; Wu, B.; Park, E.J.; Kim, J.H.; Solomon, C.; Waterman, M.L.; Hughes, C.C. Integration of the beta-catenindependent Wnt pathway with integrin signaling through the adaptor molecule Grb2. PLoS One, 2009, 4, e7841.
-
(2009)
PLoS One
, vol.4
-
-
Crampton, S.P.1
Wu, B.2
Park, E.J.3
Kim, J.H.4
Solomon, C.5
Waterman, M.L.6
Hughes, C.C.7
-
35
-
-
27744494891
-
Dual function of focal adhesion kinase in regulating integrininduced MMP-2 and MMP-9 release by human T lymphoid cells
-
Segarra, M.; Vilardell, C.; Matsumoto, K.; Esparza, J.; Lozano, E.; Serra-Pages, C.; Urbano-Marquez, A.; Yamada, K.M.; Cid, M.C. Dual function of focal adhesion kinase in regulating integrininduced MMP-2 and MMP-9 release by human T lymphoid cells. FASEB J., 2005, 19, 1875-1877.
-
(2005)
FASEB J
, vol.19
, pp. 1875-1877
-
-
Segarra, M.1
Vilardell, C.2
Matsumoto, K.3
Esparza, J.4
Lozano, E.5
Serra-Pages, C.6
Urbano-Marquez, A.7
Yamada, K.M.8
Cid, M.C.9
-
36
-
-
0242500879
-
Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
-
Chilosi, M.; Poletti, V.; Zamo, A.; Lestani, M.; Montagna, L.; Piccoli, P.; Pedron, S.; Bertaso, M.; Scarpa, A.; Murer, B.; Cancellieri, A.; Maestro, R.; Semenzato, G.; Doglioni, C. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am. J. Pathol., 2003, 162, 1495-1502.
-
(2003)
Am. J. Pathol
, vol.162
, pp. 1495-1502
-
-
Chilosi, M.1
Poletti, V.2
Zamo, A.3
Lestani, M.4
Montagna, L.5
Piccoli, P.6
Pedron, S.7
Bertaso, M.8
Scarpa, A.9
Murer, B.10
Cancellieri, A.11
Maestro, R.12
Semenzato, G.13
Doglioni, C.14
-
37
-
-
77956288500
-
Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
-
Henderson, W.R., Jr.; Chi, E.Y.; Ye, X.; Nguyen, C.; Tien, Y.T.; Zhou, B.; Borok, Z.; Knight, D.A.; Kahn, M. Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc. Natl. Acad. Sci. USA, 2010, 107, 14309-14314.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 14309-14314
-
-
Henderson Jr., W.R.1
Chi, E.Y.2
Ye, X.3
Nguyen, C.4
Tien, Y.T.5
Zhou, B.6
Borok, Z.7
Knight, D.A.8
Kahn, M.9
-
38
-
-
79958822662
-
Blockade of the Wnt/beta-catenin pathway attenuates bleomycin-induced pulmonary fibrosis
-
Kim, T.H.; Kim, S.H.; Seo, J.Y.; Chung, H.; Kwak, H.J.; Lee, S.K.; Yoon, H.J.; Shin, D.H.; Park, S.S.; Sohn, J.W. Blockade of the Wnt/beta-catenin pathway attenuates bleomycin-induced pulmonary fibrosis. Tohoku J. Exp. Med., 2011, 223, 45-54.
-
(2011)
Tohoku J. Exp. Med
, vol.223
, pp. 45-54
-
-
Kim, T.H.1
Kim, S.H.2
Seo, J.Y.3
Chung, H.4
Kwak, H.J.5
Lee, S.K.6
Yoon, H.J.7
Shin, D.H.8
Park, S.S.9
Sohn, J.W.10
-
39
-
-
13244249987
-
Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury
-
Vittal, R.; Horowitz, J.C.; Moore, B.B.; Zhang, H.; Martinez, F.J.; Toews, G.B.; Standiford, T.J.; Thannickal, V.J. Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury. Am. J. Pathol., 2005, 166, 367-375.
-
(2005)
Am. J. Pathol
, vol.166
, pp. 367-375
-
-
Vittal, R.1
Horowitz, J.C.2
Moore, B.B.3
Zhang, H.4
Martinez, F.J.5
Toews, G.B.6
Standiford, T.J.7
Thannickal, V.J.8
-
40
-
-
58149234456
-
Protein kinase inhibitors in the treatment of pulmonary fibrosis
-
Garneau-Tsodikova, S.; Thannickal, V.J. Protein kinase inhibitors in the treatment of pulmonary fibrosis. Curr. Med. Chem., 2008, 15, 2632-2640.
-
(2008)
Curr. Med. Chem
, vol.15
, pp. 2632-2640
-
-
Garneau-Tsodikova, S.1
Thannickal, V.J.2
-
41
-
-
77952763874
-
Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts
-
Cai, G.Q.; Zheng, A.; Tang, Q.; White, E.S.; Chou, C.F.; Gladson, C.L.; Olman, M.A.; Ding, Q. Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts. Exp. Cell Res., 2010, 316, 1600-1609.
-
(2010)
Exp. Cell Res
, vol.316
, pp. 1600-1609
-
-
Cai, G.Q.1
Zheng, A.2
Tang, Q.3
White, E.S.4
Chou, C.F.5
Gladson, C.L.6
Olman, M.A.7
Ding, Q.8
-
42
-
-
77951184829
-
Cellular functions of FAK kinases: Insight into molecular mechanisms and novel functions
-
Schaller, M.D. Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions. J. Cell Sci., 123, 1007-1013.
-
J. Cell Sci
, vol.123
, pp. 1007-1013
-
-
Schaller, M.D.1
-
43
-
-
0035392952
-
Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells
-
Jones, G.; Machado, J., Jr.; Merlo, A. Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells. Cancer Res., 2001, 61, 4978-4981.
-
(2001)
Cancer Res
, vol.61
, pp. 4978-4981
-
-
Jones, G.1
Machado Jr., J.2
Merlo, A.3
-
44
-
-
0038458812
-
Subcellular redistribution of focal adhesion kinase and its related nonkinase in hypertrophic myocardium
-
Yi, X.P.; Wang, X.; Gerdes, A.M.; Li, F. Subcellular redistribution of focal adhesion kinase and its related nonkinase in hypertrophic myocardium. Hypertension, 2003, 41, 1317-1323.
-
(2003)
Hypertension
, vol.41
, pp. 1317-1323
-
-
Yi, X.P.1
Wang, X.2
Gerdes, A.M.3
Li, F.4
-
45
-
-
33845702137
-
Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells
-
Oloumi, A.; Syam, S.; Dedhar, S. Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells. Oncogene, 2006, 25, 7747-7757.
-
(2006)
Oncogene
, vol.25
, pp. 7747-7757
-
-
Oloumi, A.1
Syam, S.2
Dedhar, S.3
-
46
-
-
0032516094
-
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways
-
Novak, A.; Hsu, S.C.; Leung-Hagesteijn, C.; Radeva, G.; Papkoff, J.; Montesano, R.; Roskelley, C.; Grosschedl, R.; Dedhar, S. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proc. Natl. Acad. Sci. USA, 1998, 95, 4374-4379.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4374-4379
-
-
Novak, A.1
Hsu, S.C.2
Leung-Hagesteijn, C.3
Radeva, G.4
Papkoff, J.5
Montesano, R.6
Roskelley, C.7
Grosschedl, R.8
Dedhar, S.9
-
47
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
-
Huang, S.M.; Mishina, Y.M.; Liu, S.; Cheung, A.; Stegmeier, F.; Michaud, G.A.; Charlat, O.; Wiellette, E.; Zhang, Y.; Wiessner, S.; Hild, M.; Shi, X.; Wilson, C.J.; Mickanin, C.; Myer, V.; Fazal, A.; Tomlinson, R.; Serluca, F.; Shao, W.; Cheng, H.; Shultz, M.; Rau, C.; Schirle, M.; Schlegl, J.; Ghidelli, S.; Fawell, S.; Lu, C.; Curtis, D.; Kirschner, M.W.; Lengauer, C.; Finan, P.M.; Tallarico, J.A.; Bouwmeester, T.; Porter, J.A.; Bauer, A.; Cong, F. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature, 2009, 461, 614-620.
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.M.1
Mishina, Y.M.2
Liu, S.3
Cheung, A.4
Stegmeier, F.5
Michaud, G.A.6
Charlat, O.7
Wiellette, E.8
Zhang, Y.9
Wiessner, S.10
Hild, M.11
Shi, X.12
Wilson, C.J.13
Mickanin, C.14
Myer, V.15
Fazal, A.16
Tomlinson, R.17
Serluca, F.18
Shao, W.19
Cheng, H.20
Shultz, M.21
Rau, C.22
Schirle, M.23
Schlegl, J.24
Ghidelli, S.25
Fawell, S.26
Lu, C.27
Curtis, D.28
Kirschner, M.W.29
Lengauer, C.30
Finan, P.M.31
Tallarico, J.A.32
Bouwmeester, T.33
Porter, J.A.34
Bauer, A.35
Cong, F.36
more..
-
48
-
-
79951936909
-
Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/beta-catenin signaling
-
Wang, H.; Hao, J.; Hong, C.C. Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/beta-catenin signaling. ACS Chem. Biol., 2011, 6, 192-197.
-
(2011)
ACS Chem. Biol
, vol.6
, pp. 192-197
-
-
Wang, H.1
Hao, J.2
Hong, C.C.3
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