메뉴 건너뛰기




Volumn 11, Issue 7, 2011, Pages 600-606

FAK and WNT signaling: The meeting of two pathways in cancer and development

Author keywords

Cancer; Development; Focal adhesion kinase (FAK); Wnt catenin

Indexed keywords

BETA CATENIN; FOCAL ADHESION KINASE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; WNT PROTEIN;

EID: 80051710743     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/187152011796817673     Document Type: Article
Times cited : (35)

References (48)
  • 2
    • 21644466387 scopus 로고    scopus 로고
    • Direct interaction of the N-terminal domain of focal adhesion kinase with the Nterminal transactivation domain of p53
    • Golubovskaya, V.M.; Finch, R.; Cance, W.G. Direct interaction of the N-terminal domain of focal adhesion kinase with the Nterminal transactivation domain of p53. J. Biol. Chem., 2005, 280, 25008-25021.
    • (2005) J. Biol. Chem , vol.280 , pp. 25008-25021
    • Golubovskaya, V.M.1    Finch, R.2    Cance, W.G.3
  • 3
    • 69849090245 scopus 로고    scopus 로고
    • Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2
    • Luo, S.W.; Zhang, C.; Zhang, B.; Kim, C.H.; Qiu, Y.Z.; Du, Q.S.; Mei, L.; Xiong, W.C. Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2. EMBO J., 2009, 28, 2568-2582.
    • (2009) EMBO J , vol.28 , pp. 2568-2582
    • Luo, S.W.1    Zhang, C.2    Zhang, B.3    Kim, C.H.4    Qiu, Y.Z.5    Du, Q.S.6    Mei, L.7    Xiong, W.C.8
  • 4
    • 0035661624 scopus 로고    scopus 로고
    • Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression
    • Zhao, J.; Pestell, R.; Guan, J.L. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression. Mol. Biol. Cell, 2001, 12, 4066-4077.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 4066-4077
    • Zhao, J.1    Pestell, R.2    Guan, J.L.3
  • 5
    • 0038433306 scopus 로고    scopus 로고
    • Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression
    • Zhao, J.; Bian, Z.C.; Yee, K.; Chen, B.P.; Chien, S.; Guan, J.L. Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression. Mol. Cell, 2003, 11, 1503-1515.
    • (2003) Mol. Cell , vol.11 , pp. 1503-1515
    • Zhao, J.1    Bian, Z.C.2    Yee, K.3    Chen, B.P.4    Chien, S.5    Guan, J.L.6
  • 6
    • 33748068089 scopus 로고    scopus 로고
    • New concepts regarding focal adhesion kinase promotion of cell migration and proliferation
    • Cox, B.D.; Natarajan, M.; Stettner, M.R.; Gladson, C.L. New concepts regarding focal adhesion kinase promotion of cell migration and proliferation. J. Cell Biochem., 2006, 99, 35-52.
    • (2006) J. Cell Biochem , vol.99 , pp. 35-52
    • Cox, B.D.1    Natarajan, M.2    Stettner, M.R.3    Gladson, C.L.4
  • 7
    • 34548085454 scopus 로고    scopus 로고
    • Focal adhesion kinase and p53 signaling in cancer cells
    • Golubovskaya, V.M.; Cance, W.G. Focal adhesion kinase and p53 signaling in cancer cells. Int. Rev. Cytol., 2007, 263, 103-153.
    • (2007) Int. Rev. Cytol , vol.263 , pp. 103-153
    • Golubovskaya, V.M.1    Cance, W.G.2
  • 8
    • 77956626576 scopus 로고    scopus 로고
    • Focal adhesion kinase and p53 signal transduction pathways in cancer
    • Golubovskaya, V.M.; Cance, W. Focal adhesion kinase and p53 signal transduction pathways in cancer. Front Biosci., 2010, 15, 901-912.
    • (2010) Front Biosci , vol.15 , pp. 901-912
    • Golubovskaya, V.M.1    Cance, W.2
  • 9
    • 55349105491 scopus 로고    scopus 로고
    • Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer
    • Provenzano, P.P.; Inman, D.R.; Eliceiri, K.W.; Beggs, H.E.; Keely, P.J. Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am. J. Pathol., 2008, 173, 1551-1565.
    • (2008) Am. J. Pathol , vol.173 , pp. 1551-1565
    • Provenzano, P.P.1    Inman, D.R.2    Eliceiri, K.W.3    Beggs, H.E.4    Keely, P.J.5
  • 10
    • 69349085098 scopus 로고    scopus 로고
    • The direct effect of focal adhesion kinase (FAK), dominantnegative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis
    • Golubovskaya, V.M.; Zheng, M.; Zhang, L.; Li, J.L.; Cance, W.G. The direct effect of focal adhesion kinase (FAK), dominantnegative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis. BMC Cancer, 2009, 9, 280.
    • (2009) BMC Cancer , vol.9 , pp. 280
    • Golubovskaya, V.M.1    Zheng, M.2    Zhang, L.3    Li, J.L.4    Cance, W.G.5
  • 11
    • 79952752679 scopus 로고    scopus 로고
    • Evolving therapies and FAK inhibitors for the treatment of cancer
    • Dunn, K.B.; Heffler, M.; Golubovskaya, V.M. Evolving therapies and FAK inhibitors for the treatment of cancer. Anticancer Agents Med. Chem., 2010, 10, 722-734.
    • (2010) Anticancer Agents Med. Chem , vol.10 , pp. 722-734
    • Dunn, K.B.1    Heffler, M.2    Golubovskaya, V.M.3
  • 12
    • 0036230877 scopus 로고    scopus 로고
    • DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis
    • Cohen, E.D.; Mariol, M.C.; Wallace, R.M.; Weyers, J.; Kamberov, Y.G.; Pradel, J.; Wilder, E.L. DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis. Dev Cell, 2002, 2, 437-448.
    • (2002) Dev Cell , vol.2 , pp. 437-448
    • Cohen, E.D.1    Mariol, M.C.2    Wallace, R.M.3    Weyers, J.4    Kamberov, Y.G.5    Pradel, J.6    Wilder, E.L.7
  • 13
    • 79959892925 scopus 로고    scopus 로고
    • Focal Adhesion Kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate
    • Fonar, Y.; Gutkovich, Y.E.; Root, H.; Malyarova, A.; Aamar, E.; Golubovskaya, V.M.; Elias, S.; Elkouby, Y.M.; Frank, D. Focal Adhesion Kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate. Mol Biol Cell, 2011, 22, 2409-2421.
    • (2011) Mol Biol Cell , vol.22 , pp. 2409-2421
    • Fonar, Y.1    Gutkovich, Y.E.2    Root, H.3    Malyarova, A.4    Aamar, E.5    Golubovskaya, V.M.6    Elias, S.7    Elkouby, Y.M.8    Frank, D.9
  • 15
    • 73149114381 scopus 로고    scopus 로고
    • Early activation of the betacatenin pathway in osteocytes is mediated by nitric oxide, phosphatidyl inositol-3 kinase/Akt, and focal adhesion kinase
    • Santos, A.; Bakker, A.D.; Zandieh-Doulabi, B.; de Blieck- Hogervorst, J.M.; Klein-Nulend, J. Early activation of the betacatenin pathway in osteocytes is mediated by nitric oxide, phosphatidyl inositol-3 kinase/Akt, and focal adhesion kinase. Biochem Biophys Res Commun, 2010, 391, 364-369.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 364-369
    • Santos, A.1    Bakker, A.D.2    Zandieh-Doulabi, B.3    de Blieck, H.J.M.4    Klein-Nulend, J.5
  • 16
    • 77957155478 scopus 로고    scopus 로고
    • Antagonistic interplay between mechanical forces and glucocorticoids in bone: A tale of kinases
    • Bellido, T. Antagonistic interplay between mechanical forces and glucocorticoids in bone: a tale of kinases. J Cell Biochem, 2010, 111, 1-6.
    • (2010) J Cell Biochem , vol.111 , pp. 1-6
    • Bellido, T.1
  • 17
    • 40849106249 scopus 로고    scopus 로고
    • Osteocytes, mechanosensing and Wnt signaling
    • Bonewald, L.F.; Johnson, M.L. Osteocytes, mechanosensing and Wnt signaling. Bone, 2008, 42, 606-615.
    • (2008) Bone , vol.42 , pp. 606-615
    • Bonewald, L.F.1    Johnson, M.L.2
  • 18
    • 57649237947 scopus 로고    scopus 로고
    • Betacatenin levels influence rapid mechanical responses in osteoblasts
    • Case, N.; Ma, M.; Sen, B.; Xie, Z.; Gross, T.S.; Rubin, J. Betacatenin levels influence rapid mechanical responses in osteoblasts. J Biol Chem, 2008, 283, 29196-29205.
    • (2008) J Biol Chem , vol.283 , pp. 29196-29205
    • Case, N.1    Ma, M.2    Sen, B.3    Xie, Z.4    Gross, T.S.5    Rubin, J.6
  • 19
  • 21
    • 70349216501 scopus 로고    scopus 로고
    • Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes
    • Santos, A.; Bakker, A.D.; Zandieh-Doulabi, B.; Semeins, C.M.; Klein-Nulend, J. Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes. J Orthop Res, 2009, 27, 1280-1287.
    • (2009) J Orthop Res , vol.27 , pp. 1280-1287
    • Santos, A.1    Bakker, A.D.2    Zandieh-Doulabi, B.3    Semeins, C.M.4    Klein-Nulend, J.5
  • 23
    • 77957166970 scopus 로고    scopus 로고
    • Kinase activation and osteocyte survival promoted by mechanical stimulation require LRP5/6 signaling and β-catenin accumulation, but not β-catenin/TCF-dependent transcription
    • (Abstr.)
    • Martin-Millan MPL., Vyas K, Frera G, Gortazar AR, Almeida M, Manolagas SC, Bellido T. Kinase activation and osteocyte survival promoted by mechanical stimulation require LRP5/6 signaling and β-catenin accumulation, but not β-catenin/TCF-dependent transcription. J. Bone Min. Res., 2008, 23:S400. (Abstr.).
    • (2008) J. Bone Min. Res , vol.23
    • Martin-Millan, M.P.L.1    Vyas, K.2    Frera, G.3    Gortazar, A.R.4    Almeida, M.5    Manolagas, S.C.6    Bellido, T.7
  • 27
    • 2442583529 scopus 로고    scopus 로고
    • Cloning and characterization of the promoter region of human focal adhesion kinase gene: Nuclear factor kappa B and p53 binding sites
    • Golubovskaya, V.; Kaur, A.; Cance, W. Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites. Biochim. Biophys. Acta, 2004, 1678, 111-125.
    • (2004) Biochim. Biophys. Acta , vol.1678 , pp. 111-125
    • Golubovskaya, V.1    Kaur, A.2    Cance, W.3
  • 28
    • 78649633119 scopus 로고    scopus 로고
    • P53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines
    • Anaganti, S.; Fernandez-Cuesta, L.; Langerod, A.; Hainaut, P.; Olivier, M. p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines. Cancer Lett, 2011, 300, 215-224.
    • (2011) Cancer Lett , vol.300 , pp. 215-224
    • Anaganti, S.1    Fernandez-Cuesta, L.2    Langerod, A.3    Hainaut, P.4    Olivier, M.5
  • 29
    • 0036484916 scopus 로고    scopus 로고
    • Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45
    • Katoh, M. Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45. Int. J. Oncol., 2002, 20, 373-377.
    • (2002) Int. J. Oncol , vol.20 , pp. 373-377
    • Katoh, M.1
  • 31
    • 0242493171 scopus 로고    scopus 로고
    • RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity
    • Duxbury, M.S.; Ito, H.; Benoit, E.; Zinner, M.J.; Ashley, S.W.; Whang, E.E. RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem. Biophys. Res. Commun., 2003, 311, 786-792.
    • (2003) Biochem. Biophys. Res. Commun , vol.311 , pp. 786-792
    • Duxbury, M.S.1    Ito, H.2    Benoit, E.3    Zinner, M.J.4    Ashley, S.W.5    Whang, E.E.6
  • 33
    • 45849093670 scopus 로고    scopus 로고
    • The what, where, when and how of Wnt/betacatenin signaling in pancreas development
    • Murtaugh, L.C. The what, where, when and how of Wnt/betacatenin signaling in pancreas development. Organogenesis, 2008, 4, 81-86.
    • (2008) Organogenesis , vol.4 , pp. 81-86
    • Murtaugh, L.C.1
  • 34
    • 70649105588 scopus 로고    scopus 로고
    • Integration of the beta-catenindependent Wnt pathway with integrin signaling through the adaptor molecule Grb2
    • Crampton, S.P.; Wu, B.; Park, E.J.; Kim, J.H.; Solomon, C.; Waterman, M.L.; Hughes, C.C. Integration of the beta-catenindependent Wnt pathway with integrin signaling through the adaptor molecule Grb2. PLoS One, 2009, 4, e7841.
    • (2009) PLoS One , vol.4
    • Crampton, S.P.1    Wu, B.2    Park, E.J.3    Kim, J.H.4    Solomon, C.5    Waterman, M.L.6    Hughes, C.C.7
  • 40
    • 58149234456 scopus 로고    scopus 로고
    • Protein kinase inhibitors in the treatment of pulmonary fibrosis
    • Garneau-Tsodikova, S.; Thannickal, V.J. Protein kinase inhibitors in the treatment of pulmonary fibrosis. Curr. Med. Chem., 2008, 15, 2632-2640.
    • (2008) Curr. Med. Chem , vol.15 , pp. 2632-2640
    • Garneau-Tsodikova, S.1    Thannickal, V.J.2
  • 41
    • 77952763874 scopus 로고    scopus 로고
    • Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts
    • Cai, G.Q.; Zheng, A.; Tang, Q.; White, E.S.; Chou, C.F.; Gladson, C.L.; Olman, M.A.; Ding, Q. Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts. Exp. Cell Res., 2010, 316, 1600-1609.
    • (2010) Exp. Cell Res , vol.316 , pp. 1600-1609
    • Cai, G.Q.1    Zheng, A.2    Tang, Q.3    White, E.S.4    Chou, C.F.5    Gladson, C.L.6    Olman, M.A.7    Ding, Q.8
  • 42
    • 77951184829 scopus 로고    scopus 로고
    • Cellular functions of FAK kinases: Insight into molecular mechanisms and novel functions
    • Schaller, M.D. Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions. J. Cell Sci., 123, 1007-1013.
    • J. Cell Sci , vol.123 , pp. 1007-1013
    • Schaller, M.D.1
  • 43
    • 0035392952 scopus 로고    scopus 로고
    • Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells
    • Jones, G.; Machado, J., Jr.; Merlo, A. Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells. Cancer Res., 2001, 61, 4978-4981.
    • (2001) Cancer Res , vol.61 , pp. 4978-4981
    • Jones, G.1    Machado Jr., J.2    Merlo, A.3
  • 44
    • 0038458812 scopus 로고    scopus 로고
    • Subcellular redistribution of focal adhesion kinase and its related nonkinase in hypertrophic myocardium
    • Yi, X.P.; Wang, X.; Gerdes, A.M.; Li, F. Subcellular redistribution of focal adhesion kinase and its related nonkinase in hypertrophic myocardium. Hypertension, 2003, 41, 1317-1323.
    • (2003) Hypertension , vol.41 , pp. 1317-1323
    • Yi, X.P.1    Wang, X.2    Gerdes, A.M.3    Li, F.4
  • 45
    • 33845702137 scopus 로고    scopus 로고
    • Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells
    • Oloumi, A.; Syam, S.; Dedhar, S. Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells. Oncogene, 2006, 25, 7747-7757.
    • (2006) Oncogene , vol.25 , pp. 7747-7757
    • Oloumi, A.1    Syam, S.2    Dedhar, S.3
  • 48
    • 79951936909 scopus 로고    scopus 로고
    • Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/beta-catenin signaling
    • Wang, H.; Hao, J.; Hong, C.C. Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/beta-catenin signaling. ACS Chem. Biol., 2011, 6, 192-197.
    • (2011) ACS Chem. Biol , vol.6 , pp. 192-197
    • Wang, H.1    Hao, J.2    Hong, C.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.