메뉴 건너뛰기




Volumn 12, Issue 10, 2011, Pages 1413-1416

Methotrexate: A drug of the future in ulcerative colitis?

Author keywords

Immunomodulators; Methotrexate; Therapy; Ulcerative colitis

Indexed keywords

CYCLOSPORIN; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE; PLACEBO; PREDNISONE;

EID: 80051705228     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/138945011796818252     Document Type: Article
Times cited : (8)

References (44)
  • 1
    • 2442563304 scopus 로고    scopus 로고
    • Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence and environmental factors
    • Loftus AV. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence and environmental factors. Gastroenterology 2004; 126: 1504-1517.
    • (2004) Gastroenterology , vol.126 , pp. 1504-1517
    • Loftus, A.V.1
  • 2
    • 58149390157 scopus 로고    scopus 로고
    • An update on the epidemiology of inflammatory bowel disease in Asia
    • Thia KT, Loftus EV, Sandborn WJ, Yang SK. An update on the epidemiology of inflammatory bowel disease in Asia. Am J Gastroenterol 2008; 103: 3167-3182.
    • (2008) Am J Gastroenterol , vol.103 , pp. 3167-3182
    • Thia, K.T.1    Loftus, E.V.2    Sandborn, W.J.3    Yang, S.K.4
  • 3
    • 0034903792 scopus 로고    scopus 로고
    • The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study
    • Faubion WA, Loftus EV, Harmsen WS, et al. The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 2001; 121: 255-260.
    • (2001) Gastroenterology , vol.121 , pp. 255-260
    • Faubion, W.A.1    Loftus, E.V.2    Harmsen, W.S.3
  • 4
    • 67049137968 scopus 로고    scopus 로고
    • Clinical course during the first ten years of ulcerative colitis: Results from a population-based inception cohort (IBSEN study)
    • Solberg IC, Lygren I, Jahnsen J, et al. Clinical course during the first ten years of ulcerative colitis: results from a population-based inception cohort (IBSEN study). Scand J Gastro 2009; 44: 431-440.
    • (2009) Scand J Gastro , vol.44 , pp. 431-440
    • Solberg, I.C.1    Lygren, I.2    Jahnsen, J.3
  • 5
    • 38749095183 scopus 로고    scopus 로고
    • European evidence-based consensus on ulcerative colitis: Current management
    • Travis S, Stange EF, Lemann M, et al. European evidence-based consensus on ulcerative colitis: current management. J Crohn Colitis 2008; 2: 24-62.
    • (2008) J Crohn Colitis , vol.2 , pp. 24-62
    • Travis, S.1    Stange, E.F.2    Lemann, M.3
  • 6
    • 33846213645 scopus 로고    scopus 로고
    • Once daily high concentration MMX mesalamine in active ulcerative colitis
    • Kamm, M, Sandborn W, Gassull M, et al. Once daily high concentration MMX mesalamine in active ulcerative colitis. Gastroenterology 2007; 132: 66-75.
    • (2007) Gastroenterology , vol.132 , pp. 66-75
    • Kamm, M.1    Sandborn, W.2    Gassull, M.3
  • 7
    • 0016293798 scopus 로고
    • Azathioprine in ulcerative colitis: Final report on a controlled therapeutic trial
    • Jewell DP, Truelove SC. Azathioprine in ulcerative colitis: final report on a controlled therapeutic trial. Br Med J 1974; 4: 627-630.
    • (1974) Br Med J , vol.4 , pp. 627-630
    • Jewell, D.P.1    Truelove, S.C.2
  • 8
    • 0016607713 scopus 로고
    • A double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis
    • Caprilli R, Carratu R, Babbini M, et al. A double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Dig Dis Sci 1975; 20: 115-120.
    • (1975) Dig Dis Sci , vol.20 , pp. 115-120
    • Caprilli, R.1    Carratu, R.2    Babbini, M.3
  • 10
    • 0020048415 scopus 로고
    • Controlled trial of azathioprine in chronic ulcerative colitis
    • Kirk AP, Lennard-Jones JE. Controlled trial of azathioprine in chronic ulcerative colitis. BMJ 1982; 284: 1291-1292.
    • (1982) BMJ , vol.284 , pp. 1291-1292
    • Kirk, A.P.1    Lennard-Jones, J.E.2
  • 11
    • 0026693139 scopus 로고
    • Randomised controlled trial of azathioprine withdrawal in ulcerative colitis
    • Hawthorne AB, Logan RFA, Hawkey CJ, et al. Randomised controlled trial of azathioprine withdrawal in ulcerative colitis. BMJ 1992; 305: 2022.
    • (1992) BMJ , vol.305 , pp. 2022
    • Hawthorne, A.B.1    Logan, R.F.A.2    Hawkey, C.J.3
  • 12
    • 29244457275 scopus 로고    scopus 로고
    • Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis
    • Ardizzone S, Maconi G, Russo A, et al. Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut 2006; 55: 47-53.
    • (2006) Gut , vol.55 , pp. 47-53
    • Ardizzone, S.1    Maconi, G.2    Russo, A.3
  • 13
    • 34948824782 scopus 로고    scopus 로고
    • Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine
    • Vernier-Massouille G, Cosnes J, Lemann M, et al. Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine. Gut 2007; 56: 1404-1409.
    • (2007) Gut , vol.56 , pp. 1404-1409
    • Vernier-Massouille, G.1    Cosnes, J.2    Lemann, M.3
  • 14
    • 70449100743 scopus 로고    scopus 로고
    • Lymphoproilferative disorders in patients receiving thiopurines for inflammatory bowel disease, a prospective observational cohort study
    • Beaugerie L, Brousse N, Bouvier AM, et al. Lymphoproilferative disorders in patients receiving thiopurines for inflammatory bowel disease, a prospective observational cohort study. Lancet 2009; 374: 1617-1625.
    • (2009) Lancet , vol.374 , pp. 1617-1625
    • Beaugerie, L.1    Brousse, N.2    Bouvier, A.M.3
  • 15
    • 28844473957 scopus 로고    scopus 로고
    • Infliximab for induction and maintenance therapy for ulcerative colitis
    • Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005; 353: 2462-2476.
    • (2005) N Engl J Med , vol.353 , pp. 2462-2476
    • Rutgeerts, P.1    Sandborn, W.J.2    Feagan, B.G.3
  • 16
    • 0028939349 scopus 로고
    • The effect of age and renal function on the efficacy and toxicity of methotrexate in rheumatoid arthritis
    • Rheumatoid arthritis clinical trial archive group
    • Rheumatoid arthritis clinical trial archive group. The effect of age and renal function on the efficacy and toxicity of methotrexate in rheumatoid arthritis. J Rheumatol 1995; 22: 218-223.
    • (1995) J Rheumatol , vol.22 , pp. 218-223
  • 17
    • 26844561979 scopus 로고    scopus 로고
    • Reduction of efficacy of methotrexate by the use of folic acid
    • Khanna D, Park GS, Paulus HE, et al. Reduction of efficacy of methotrexate by the use of folic acid. Arthritis Rheum 2005; 52: 3030-3038.
    • (2005) Arthritis Rheum , vol.52 , pp. 3030-3038
    • Khanna, D.1    Park, G.S.2    Paulus, H.E.3
  • 18
    • 78049477991 scopus 로고    scopus 로고
    • Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: A case control study
    • Laharie D, Seneschal J, Schaeverbeke T, et al. Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case control study. J Hepatol 2010; 53: 1035-1040.
    • (2010) J Hepatol , vol.53 , pp. 1035-1040
    • Laharie, D.1    Seneschal, J.2    Schaeverbeke, T.3
  • 19
    • 0036624739 scopus 로고    scopus 로고
    • Lymphomas in rheumatoid arthritis patients treated with methotrexate: A 3-year prospective study in France
    • Mariette X, Cazals-Hatem D, Warszawki J, Liote F, Balandraud N, Sibilia J. Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France. Blood 2002; 99: 3909-3915.
    • (2002) Blood , vol.99 , pp. 3909-3915
    • Mariette, X.1    Cazals-Hatem, D.2    Warszawki, J.3    Liote, F.4    Balandraud, N.5    Sibilia, J.6
  • 20
    • 67549096874 scopus 로고    scopus 로고
    • Multinational evidencebased recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: Integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative
    • Visser K, Katchamart W, Loza E, et al. Multinational evidencebased recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative. Ann Rheum Dis 2009; 68: 1086-1093.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1086-1093
    • Visser, K.1    Katchamart, W.2    Loza, E.3
  • 21
    • 0030791403 scopus 로고    scopus 로고
    • Why intramuscular methotrexate may be more efficacious than oral dosing in patients with rheumatoid arthritis
    • Hamilton RA, Kremer JM. Why intramuscular methotrexate may be more efficacious than oral dosing in patients with rheumatoid arthritis. Br J Rheumatol 1997; 36: 86-90.
    • (1997) Br J Rheumatol , vol.36 , pp. 86-90
    • Hamilton, R.A.1    Kremer, J.M.2
  • 22
    • 0041843894 scopus 로고    scopus 로고
    • Bioavailability of oral vs. subcutaneous low-dose methotrexate in patients with Crohn's disease
    • Kurnik D, Loebstein R, Fishbein E, et al. Bioavailability of oral vs. subcutaneous low-dose methotrexate in patients with Crohn's disease. Aliment Pharmacol Ther 2003; 18: 57-63.
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 57-63
    • Kurnik, D.1    Loebstein, R.2    Fishbein, E.3
  • 23
    • 0024216625 scopus 로고
    • Pharmacokinetics of subcutaneous methotrexate
    • Balis FM, Mirro J Jr, Reaman GH, et al. Pharmacokinetics of subcutaneous methotrexate. J Clin Oncol 1988; 6: 1882-1886.
    • (1988) J Clin Oncol , vol.6 , pp. 1882-1886
    • Balis, F.M.1    Mirro Jr., J.2    Reaman, G.H.3
  • 24
    • 0027744086 scopus 로고
    • A comparison of low dose methotrexate bioavailability: Oral solution, oral tablet, subcutaneous and intramuscular dosing
    • Jundt JW, Browne BA, Fiocco GP, et al. A comparison of low dose methotrexate bioavailability: oral solution, oral tablet, subcutaneous and intramuscular dosing. J Rheumatol 1993; 20: 1845-1849.
    • (1993) J Rheumatol , vol.20 , pp. 1845-1849
    • Jundt, J.W.1    Browne, B.A.2    Fiocco, G.P.3
  • 25
    • 0025190680 scopus 로고
    • Pharmacokinetics of methotrexate administered by intramuscular and subcutaneous injections in patients with rheumatoid arthritis
    • Brooks PJ, Spruill WJ, Parish RC, et al. Pharmacokinetics of methotrexate administered by intramuscular and subcutaneous injections in patients with rheumatoid arthritis. Arthritis Rheum 1990; 33: 91-94.
    • (1990) Arthritis Rheum , vol.33 , pp. 91-94
    • Brooks, P.J.1    Spruill, W.J.2    Parish, R.C.3
  • 26
    • 0028899859 scopus 로고
    • Methotrexate for the treatment of Crohn's disease
    • The North American Crohn's Study Group Investigators
    • Feagan BG, Rochon J, Fedorak RN, et al. Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators. N Engl J Med 1995 2; 332: 292-299.
    • (1995) N Engl J Med , vol.2 , Issue.332 , pp. 292-299
    • Feagan, B.G.1    Rochon, J.2    Fedorak, R.N.3
  • 27
    • 0034214336 scopus 로고    scopus 로고
    • A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease
    • North American Crohn's Study Group Investigators
    • Feagan BG, Fedorak RN, Irvine EJ, et al. A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators. N Engl J Med 2000; 342: 1627-1632.
    • (2000) N Engl J Med , vol.342 , pp. 1627-1632
    • Feagan, B.G.1    Fedorak, R.N.2    Irvine, E.J.3
  • 28
    • 0030784425 scopus 로고    scopus 로고
    • Methotrexate in chronic active Crohn's disease: A double-blind, randomized, Israeli multicenter trial
    • Oren R, Moshkowitz M, Odes S, et al. Methotrexate in chronic active Crohn's disease: a double-blind, randomized, Israeli multicenter trial. Am J Gastroenterol 1997; 92: 2203-2209.
    • (1997) Am J Gastroenterol , vol.92 , pp. 2203-2209
    • Oren, R.1    Moshkowitz, M.2    Odes, S.3
  • 29
    • 0009447497 scopus 로고    scopus 로고
    • Methotrexate in Crohn's disease: Results of a randomized, double-blind, placebo-controlled trial
    • Arora S, Katkov W, Cooley J, et al. Methotrexate in Crohn's disease: results of a randomized, double-blind, placebo-controlled trial. Hepatogastroenterology 1999; 46: 1724-1729.
    • (1999) Hepatogastroenterology , vol.46 , pp. 1724-1729
    • Arora, S.1    Katkov, W.2    Cooley, J.3
  • 30
    • 75149161836 scopus 로고    scopus 로고
    • The second European evidence-based consensus on the diagnosis and managements of Crohn's disease: Current management
    • Dignass A, Van Assche G, Lindsey GO, et al. The second European evidence-based consensus on the diagnosis and managements of Crohn's disease: current management. J Crohn Colitis 2010; 4: 28-62.
    • (2010) J Crohn Colitis , vol.4 , pp. 28-62
    • Dignass, A.1    van Assche, G.2    Lindsey, G.O.3
  • 31
    • 84859421822 scopus 로고    scopus 로고
    • http://www.snfge.org/data/FlashConfs/2006/048/
  • 32
    • 0024517127 scopus 로고
    • Methotrexate use in inflammatory bowel disease patients who have failed azathioprine or 6-mercaptopurine
    • Kozarek RA, Patterson DJ, Botoman VA, Ball TJ, Gelfand MD. Methotrexate use in inflammatory bowel disease patients who have failed azathioprine or 6-mercaptopurine. Ann Int Med 1989; 110: 353-356.
    • (1989) Ann Int Med , vol.110 , pp. 353-356
    • Kozarek, R.A.1    Patterson, D.J.2    Botoman, V.A.3    Ball, T.J.4    Gelfand, M.D.5
  • 33
  • 34
    • 0036791285 scopus 로고    scopus 로고
    • Azathioprine or methotrexate in the treatment of patients with steroid-dependent or steroid-resistant ulcerative colitis: Results of an open-label study on efficacy and tolerability in inducing and maintaining remission
    • Paoluzi OA, Pica R, Marcheggiano A, et al. Azathioprine or methotrexate in the treatment of patients with steroid-dependent or steroid-resistant ulcerative colitis: results of an open-label study on efficacy and tolerability in inducing and maintaining remission. Aliment Pharmacol Ther 2003; 16: 1751-1759.
    • (2003) Aliment Pharmacol Ther , vol.16 , pp. 1751-1759
    • Paoluzi, O.A.1    Pica, R.2    Marcheggiano, A.3
  • 36
    • 4444319475 scopus 로고    scopus 로고
    • Experience with the use of low dose methotrexate for inflammatory bowel disease
    • Soon SY, Ansari A, Yaneza M, et al. Experience with the use of low dose methotrexate for inflammatory bowel disease. Eur J Gastroenterol Hepatol 2004; 16: 921-926.
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , pp. 921-926
    • Soon, S.Y.1    Ansari, A.2    Yaneza, M.3
  • 38
    • 44949155702 scopus 로고    scopus 로고
    • A single center experience of methotrexate in the treatment of Crohn's disease and ulcerative colitis: A case for subcutaneous administration
    • Nathan DM, Iser JH, Gibson PR. A single center experience of methotrexate in the treatment of Crohn's disease and ulcerative colitis: a case for subcutaneous administration. J Gastroenterol Hepatol 2008; 23: 954-958.
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 954-958
    • Nathan, D.M.1    Iser, J.H.2    Gibson, P.R.3
  • 39
    • 68949209778 scopus 로고    scopus 로고
    • Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine/mercaptopurine
    • Wahed M, Louis-Auguste JR, Baxter LM, et al. Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine/mercaptopurine. Aliment Pharmacol Ther 2009; 30: 614-620.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 614-620
    • Wahed, M.1    Louis-Auguste, J.R.2    Baxter, L.M.3
  • 40
    • 77957238090 scopus 로고    scopus 로고
    • Methotrexate in pediatric ulcerative colitis, a retrospective survey at a single tertiary referral center
    • Aloi M, Di Nardo G, Conte F, et al. Methotrexate in pediatric ulcerative colitis, a retrospective survey at a single tertiary referral center. Alim Pharm Ther 2010; 32(8): 1017-1022.
    • (2010) Alim Pharm Ther , vol.32 , Issue.8 , pp. 1017-1022
    • Aloi, M.1    Di Nardo, G.2    Conte, F.3
  • 41
    • 9244264980 scopus 로고    scopus 로고
    • Methotrexate in chonic active ulcerative colitis: A double blind randomized israeli multicenter trial
    • Oren R, Arber N, Odes S, et al. Methotrexate in chonic active ulcerative colitis: a double blind randomized israeli multicenter trial. Gastroenterology 1996; 110: 1416-1421.
    • (1996) Gastroenterology , vol.110 , pp. 1416-1421
    • Oren, R.1    Arber, N.2    Odes, S.3
  • 42
    • 0033679444 scopus 로고    scopus 로고
    • Moreno-Otero R. 6- mercaptopurine or methotrexate added to prenisone induces and maintains remission in steroid-dependent inflammatory bowel disease
    • Maté-Jiménez J, Hermida C, Cantero-Perona J, Moreno-Otero R. 6- mercaptopurine or methotrexate added to prenisone induces and maintains remission in steroid-dependent inflammatory bowel disease. Eur J Gastroenterol Hepatol 2000; 12: 1227-1233.
    • (2000) Eur J Gastroenterol Hepatol , vol.12 , pp. 1227-1233
    • Maté-Jiménez, J.1    Hermida, C.2    Cantero-Perona, J.3
  • 43
    • 0033406747 scopus 로고    scopus 로고
    • A randomized dose response and pharmacokinetic study of methotrexate for refractory inflammatory Crohn's disease and ulcerative colitis
    • Egan LJ, Sandborn WJ, Tremaine WJ, et al. A randomized dose response and pharmacokinetic study of methotrexate for refractory inflammatory Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther 1999; 13: 1597-1604.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1597-1604
    • Egan, L.J.1    Sandborn, W.J.2    Tremaine, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.