Reduction of the efficacy of methotrexate by the use of folic acid: Post hoc analysis from two randomized controlled studies

Arthritis and Rheumatism

Volumn 52, Issue 10, 2005, Pages 3030-3038

  Khanna, Dinesh ^a,g   Park, Grace S ^b   Paulus, Harold E ^b   Simpson, Karen M ^c   Elashoff, David ^b   Cohen, Stanley B ^d   Emery, Paul ^e   Dorrier, Catharine ^f   Furst, Daniel E ^b  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SANOFI   (France)

^d RADIANT RESEARCH   (United States)

^e UNIVERSITY OF LEEDS   (United Kingdom)

^f HD Consulting   (United States)

^g UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CORTICOSTEROID; DISEASE MODIFYING ANTIRHEUMATIC DRUG; FOLIC ACID; LEFLUNOMIDE; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; RHEUMATOID FACTOR;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALOPECIA; APHTHOUS ULCER; ARTHRITIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE ACTIVITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DYSPEPSIA; FATIGUE; FEMALE; HEADACHE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; LIVER FUNCTION TEST; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; MOUTH ULCER; NAUSEA; PHASE 3 CLINICAL TRIAL; PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH; RHEUMATOID ARTHRITIS; STOMATITIS; TREATMENT OUTCOME;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DRUG INTERACTIONS; FEMALE; FOLIC ACID; HEMATINICS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; ISOXAZOLES; MALE; METHOTREXATE; MIDDLE AGED; TREATMENT OUTCOME;

EID: 26844561979     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21295     Document Type: Article

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