CD40L co-stimulation from CD8 + to CD4 + effector memory T cells supports CD4 + expansion

Immunology and Cell Biology

Volumn 89, Issue 6, 2011, Pages 670-680

  Xydia, Maria ^a   Ge, Yingzi ^a   Quitsch, Ulrike ^a   Beckhove, Philipp ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

CD40L CD40 interactions; effector memory; help

Indexed keywords

CD40 LIGAND;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIVISION; CELL INTERACTION; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; EFFECTOR MEMORY T CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MEMORY T LYMPHOCYTE; NORMAL HUMAN; PROTEIN EXPRESSION; UPREGULATION;

ANTIGENS, CD40; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELL PROLIFERATION; COCULTURE TECHNIQUES; GENE EXPRESSION REGULATION; HUMANS; IMMUNOLOGIC MEMORY; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 80051694799     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2010.153     Document Type: Article

References (34)

1. + T-cell memory: known facts, deserted roads, muddy waters, and possible dead ends. Immunol Rev 2006; 211: 182-196. (Pubitemid 43882971)
2. Michie CA, McLean A, Alcock C, Beverley PC. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature 1992; 360: 264-265.
3. Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science 1996; 272: 60-66. (Pubitemid 26110755)
4. Campbell JJ, Bowman EP, Murphy K, Youngman KR, Siani MA, Thompson DA et al. 6-C-kine (SLC), a lymphocyte adhesion triggering chemokine expressed by high endothelium, is an agonist for the MIP-3beta receptor CCR7. J Cell Biol 1998; 141: 1053-1059. (Pubitemid 28243971)
5. Forster R, Schubel A, Breitfeld D, Kremmer E, Renner-Muller I, Wolf E et al. CCR7 coordinates the primary immune response by establishing functional microenviron-ments in secondary lymphoid organs. Cell 1999; 99: 23-33. (Pubitemid 29468627)
6. Sallusto F, Lenig D, Förster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999; 401: 708-712.
7. Sallusto F, Geginat J, Lanzavecchia A. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol 2004; 22: 745-763. (Pubitemid 38680440)
8. Woodland DL, Kohlmeier JE. Migration, maintenance and recall of memory T cells in peripheral tissues. Nat Rev Immunol 2009; 9: 153-161.
9. + effector memory T cells. J Immunol 2005; 175: 1433-1439. (Pubitemid 41023042)
10. + T Cells: when, where, and how. Annu Rev Immunol 2006; 24: 519-540.
11. + T cell memory. Science 2002; 297: 2060-2063.
12. + T lymphocytes. Nature 2003; 421: 852-856. (Pubitemid 36254145)
13. Shedlock DJ, Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003; 300: 337-339. (Pubitemid 36433726)
14. Sun JC, Bevan MJ. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003; 300: 339-342. (Pubitemid 36433727)
15. Marzo AL, Vezys V, Klonowski KD, Lee SJ, Muralimohan G, Moore M et al. Fully functional memory CD8 T cells in the absence of CD4 T cells. J Immunol 2004; 173: 969-975. (Pubitemid 38924270)
16. + T cells via antigen cross-presentation. J Immunol 2006; 176: 7288-7300. (Pubitemid 43849029)
17. Grewal IS, Flavell RA. CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 1998; 16: 111-135. (Pubitemid 28183361)
18. Greenwald RJ, Freeman GJ, Sharpe AH. The B7 family revisited. Annu Rev Immunol 2005; 23: 515-548. (Pubitemid 40563179)
19. Schönbeck U, Libby P. The CD40/CD154 receptor/ligand dyad (Review). Cell Mol Life Sci 2001; 58: 4-43.
20. Bennett SRM, Carbone FR, Karamalis F, Flavell RA, Miller JFAP, Heath WR. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 1998; 393: 478-480.
21. Ridge JP, Di Rosa F, Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 1998; 393: 474-478.
22. Schoenberger SP, Toes REM, van der Voort EIH, Offringa R, Melief CJM. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 1998; 393: 480-483.
23. Lee BO, Hartson L, Randall TD. CD40-deficient, influenza-specific CD8 memory T cells develop and function normally in CD40-deficient environment. J Exp Med 2003; 198: 1759-1764. (Pubitemid 37494168)
24. Sun JC, Bevan MJ. Cutting edge: long-lived CD8 memory and protective immunity in the absence of CD40 expression on CD8 T cells. J Immunol 2004; 172: 3385-3389. (Pubitemid 38337916)
25. Agnellini P, Wiesel M, Schwarz K, Wolint P, Bachmann MF, Oxenius A. Kinetic and mechanistic requirements for helping CD8 T cells. J Immunol 2008; 180: 1517-1525.
26. de Goer de Herve MG, Dembele B, Vallee M, Herr F, Cariou A, Taoufik Y. Direct CD4 help provision following interaction of memory CD4 and CD8 T cells with distinct antigen-presenting dendritic cells. J Immunol 2010; 185: 1028-1036.
27. Johnson S, Zhan Y, Sutherland RM, Mount AM, Bedoui S, Brady JL et al. Selected Tolllike receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells. Immunity 2009; 30: 218-227.
28. Hernandez MG, Shen L, Rock KL. CD40-CD40L interaction between dendritic cells and CD8 T cells is needed to stimulate maximal T cells responses in the absence of CD4 T cell help. J Immunol 2007; 178: 2844-2852. (Pubitemid 46333162)
29. + effector T cells. J Immunol 2001; 167: 1379-1386. (Pubitemid 32703135)
30. Gunzer M, Schafer A, Borgmann S, Grabbe S, Zanker KS, Brocker EB et al. Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. Immunity 2000; 13: 323-332.
31. Harris NL, Watt V, Ronchese F, Le Gros G. Differential T cell function and fate in lymph node and nonlymphoid tissues. J Exp Med 2002; 195: 317-326. (Pubitemid 34461489)
32. Anolik J, Looney RJ, Bottaro A, Sanz I, Young F. Down-regulation of CD20 on B cells upon CD40 activation. Eur J Immunol 2003; 33: 2398-2409. (Pubitemid 37138972)
33. Zirlik A, Maier C, Gerdes N, MacFarlane L, Soosairajah J, Bavendiek U et al. CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-I. Circulation 2007; 115: 1571-1580. (Pubitemid 46648642)
34. Christensen JE, Andreasen SO, Christensen JP, Thomsen AR. CD11b expression as a marker to distinguish between recently activated effector CD8+ T cells and memory cells. Int Immunol 2001; 13: 593-600. (Pubitemid 32293529)