메뉴 건너뛰기




Volumn 31, Issue 9, 2011, Pages 2899-2906

Down-regulation of expression of interleukin-6 and its receptor results in growth inhibition of MCF-7 breast cancer cells

Author keywords

Antisense; Breast cancer; Interleukin 6; Interleukin 6 receptor; MCF 7; Oligodeoxynucleotides

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA;

EID: 80051616701     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (46)

References (50)
  • 1
    • 0342352274 scopus 로고
    • The biology of interleukin-6
    • Kishimoto T: The biology of interleukin-6. Blood 14: 1-10, 1990.
    • (1990) Blood , vol.14 , pp. 1-10
    • Kishimoto, T.1
  • 2
    • 0029099539 scopus 로고
    • Prognostic factors in multiple myeloma
    • Dayt
    • Kyle RA: Prognostic factors in multiple myeloma. Stem Cell (Dayt) 13(Suppl2): 56-63, 1995.
    • (1995) Stem Cell , vol.13 , Issue.SUPPL. 2 , pp. 56-63
    • Kyle, R.A.1
  • 3
    • 0031046182 scopus 로고    scopus 로고
    • Clinical correlates of elevated serum levels of interleukin-6 in patients with untreated Hodgkin's disease
    • DOI 10.1016/S0002-9343(96)00352-X, PII S000293439600352X
    • Seymour JF, Talpaz M, Hagemeister FB, Cabanillas F and Kurzrock R: Clinical correlates of elevated serum levels of interleukin-6 in patients with untreated Hodgkin's disease. Am J Med 102: 21-28, 1997. (Pubitemid 27089983)
    • (1997) American Journal of Medicine , vol.102 , Issue.1 , pp. 21-28
    • Seymour, J.F.1    Talpaz, M.2    Hagemeister, F.B.3    Cabanillas, F.4    Kurzrock, R.5
  • 7
    • 0036160521 scopus 로고    scopus 로고
    • Preoperative plasma levels of interleukin-6 and its soluble receptor predict disease recurrence and survival of patients with bladder cancer
    • Andrews B, Shariat SF, Kim JH, Wheeler TM, Slawin KM and Lerner SP: Preoperative plasma levels of interleukin-6 and its soluble receptor predict disease recurrence and survival of patients with bladder cancer. J Urol 167: 1475-1481, 2002. (Pubitemid 34132135)
    • (2002) Journal of Urology , vol.167 , Issue.3 , pp. 1475-1481
    • Andrews, B.1    Shariat, S.F.2    Kim, J.-H.3    Wheeler, T.M.4    Slawin, K.M.5    Lerner, S.P.6
  • 13
    • 0026161656 scopus 로고
    • Interleukin-6 and 12-O-tetradecanoyl phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells
    • Tamm I, Cardinale I and Sehgal P: Interleukin-6 and 12-O-tetradecanoyl phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells. Cytokine 3: 212-223, 1991.
    • (1991) Cytokine , vol.3 , pp. 212-223
    • Tamm, I.1    Cardinale, I.2    Sehgal, P.3
  • 15
    • 0026760711 scopus 로고
    • Interleukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells
    • Ullmann CD, Schlom J and Greiner JW: Interleukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells. J Immunother 12: 231-241, 1992.
    • (1992) J Immunother , vol.12 , pp. 231-241
    • Ullmann, C.D.1    Schlom, J.2    Greiner, J.W.3
  • 16
    • 80051609834 scopus 로고    scopus 로고
    • Interleukin-6 enhances tumor antigen expression in the MCF-7 human breast cancer cell line and breast cancer patients
    • Jiang XP, Yang DC, Elliott RL and Head JF: Interleukin-6 enhances tumor antigen expression in the MCF-7 human breast cancer cell line and breast cancer patients. Breast Cancer Res Treat 57: 95a, 1999.
    • (1999) Breast Cancer Res Treat , vol.57
    • Jiang, X.P.1    Yang, D.C.2    Elliott, R.L.3    Head, J.F.4
  • 17
    • 0024393839 scopus 로고
    • Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
    • DOI 10.1016/0092-8674(89)90438-8
    • Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, Hirano T and Kishimoto T: Interleukin-6 triggers the association of its receptor with a possible signal transducer, GP130. Cell 58: 573-581, 1989. (Pubitemid 19203542)
    • (1989) Cell , vol.58 , Issue.3 , pp. 573-581
    • Taga, T.1    Hibi, M.2    Hirata, Y.3    Yamasaki, K.4    Yasukawa, K.5    Matsuda, T.6    Hirano, T.7    Kishimoto, T.8
  • 18
    • 0033762663 scopus 로고    scopus 로고
    • Signal through GP130 activated by soluble interleukin-6 receptor (IL-6R) and IL-6 or IL-6R/IL-6 fusion protein enhances ex vivo expansion of human peripheral blood-derived hematopoietic progenitors
    • Kimura T, Wang J, Minamiguchi H, Fujiki H, Harada S, Okuda K, Kaneko H, Yokota S, Yasukawa K, Abe T and Sonoda Y: Signal through GP130 activated by soluble interleukin-6 receptor (IL-6R) and IL-6 or IL-6R/IL-6 fusion protein enhances ex vivo expansion of human peripheral blood-derived hematopoietic progenitors. Stem Cells 18: 444-452, 2000.
    • (2000) Stem Cells , vol.18 , pp. 444-452
    • Kimura, T.1    Wang, J.2    Minamiguchi, H.3    Fujiki, H.4    Harada, S.5    Okuda, K.6    Kaneko, H.7    Yokota, S.8    Yasukawa, K.9    Abe, T.10    Sonoda, Y.11
  • 21
    • 0025881291 scopus 로고
    • Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells
    • Schooltink H, Stoyan T, Lenz D, Schmitz H, Hirano T, Kishimoto T, Henrich P and Rose-John S: Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells. Biochem J 277: 659-664, 1991.
    • (1991) Biochem J , vol.277 , pp. 659-664
    • Schooltink, H.1    Stoyan, T.2    Lenz, D.3    Schmitz, H.4    Hirano, T.5    Kishimoto, T.6    Henrich, P.7    Rose-John, S.8
  • 22
    • 14844350833 scopus 로고
    • Effect of IL-6 receptor antisense oligodeoxynucleotide on in vitro proliferation of myeloma cells
    • Keller T and Ershler WB: Effect of IL-6 receptor antisense oligodeoxynucleotide on in vitro proliferation of myeloma cells. J Immunol 154: 4091-4098, 1995.
    • (1995) J Immunol , vol.154 , pp. 4091-4098
    • Keller, T.1    Ershler, W.B.2
  • 23
    • 0035133050 scopus 로고    scopus 로고
    • Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells
    • Badache A and Hynes NE: Interleukin-6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells. Cancer Res 61: 383-391, 2001. (Pubitemid 32095742)
    • (2001) Cancer Research , vol.61 , Issue.1 , pp. 383-391
    • Badache, A.1    Hynes, N.E.2
  • 24
    • 0037331278 scopus 로고    scopus 로고
    • Accelerated in vivo growth of prostate tumors that up-regulate interleukin-6 is associated with reduced retinoblastoma protein expression and activation of the mitogen-activated protein kinase pathway
    • Steiner H, Godoy-Tundidor S, Rogatsch H, Berger AP, Fuchs D, Comuzzi B, Bartsch G, Hobisch A and Culig Z: Accelerated in vivo growth of prostate tumors that up-regulate interleukin-6 is associated with reduced retinoblastoma protein expression and activation of the mitogen-activated protein kinase pathway. Am J Pathol 162: 655-663, 2003. (Pubitemid 36267872)
    • (2003) American Journal of Pathology , vol.162 , Issue.2 , pp. 655-663
    • Steiner, H.1    Godoy-Tundidor, S.2    Rogatsch, H.3    Berger, A.P.4    Fuchs, D.5    Comuzzi, B.6    Bartsch, G.7    Hobisch, A.8    Culig, Z.9
  • 25
    • 0034599429 scopus 로고    scopus 로고
    • Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells
    • DOI 10.1016/S0304-3835(99)00401-2, PII S0304383599004012
    • Schneider MR, Hoeflich A, Fischer JR, Wolf E, Sordat B and Lahm H: Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells. Cancer Lett 151, 31-38, 2000. (Pubitemid 30155582)
    • (2000) Cancer Letters , vol.151 , Issue.1 , pp. 31-38
    • Schneider, M.R.1    Hoeflich, A.2    Fischer, J.R.3    Wolf, E.4    Sordat, B.5    Lahm, H.6
  • 26
    • 0029937459 scopus 로고    scopus 로고
    • Interleukin-6 inhibits apoptosis and tumour necrosis factor induced proliferation of B-chronic lymphocytic leukaemia
    • Reittie JE, Yong KL, Panayiotidis P and Hoffbrand AV: Interleukin-6 inhibits apoptosis and tumour necrosis factor induced proliferation of B-chronic lymphocytic leukaemia. Leuk Lymphoma 22: 83-90, 1996. (Pubitemid 26177722)
    • (1996) Leukemia and Lymphoma , vol.22 , Issue.1-2 , pp. 83-90
    • Reittie, J.E.1    Yong, K.L.2    Panayiotidis, P.3    Hoffbrand, A.V.4
  • 27
    • 0027396955 scopus 로고
    • Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression
    • Lu C and Kerbel RS: Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression. J Cell Biol 120: 1281-1288, 1993. (Pubitemid 23064182)
    • (1993) Journal of Cell Biology , vol.120 , Issue.5 , pp. 1281-1288
    • Lu, C.1    Kerbel, R.S.2
  • 29
    • 0033951934 scopus 로고    scopus 로고
    • Tumor growth inhibition effect of hIL-6 on colon cancer cells transfected with the target gene by retroviral vector
    • Xiao B, Jing B, Zhang YL, Zhou DY and Zhang WD: Tumor growth inhibition effect of hIL-6 on colon cancer cells transfected with the target gene by retroviral vector. World J Gastroenterol 6: 89-92, 2000. (Pubitemid 30093070)
    • (2000) World Journal of Gastroenterology , vol.6 , Issue.1 , pp. 89-92
    • Xiao, B.1    Jing, B.2    Zhang, Y.L.3    Zhou, D.Y.4    Zhang, W.D.5
  • 30
    • 0031890458 scopus 로고    scopus 로고
    • Interferon-gamma and interleukin-6 inhibit proliferation in human melanoma cells by different signalling pathways
    • DOI 10.1097/00008390-199802000-00005
    • Fontaine V, Mahieu M and Content J: Interferon-gamma and interleukin-6 inhibit proliferation in human melanoma cells by different signalling pathways. Melanoma Res 8: 24-30, 1998. (Pubitemid 28114298)
    • (1998) Melanoma Research , vol.8 , Issue.1 , pp. 24-30
    • Fontaine, V.1    Mahieu, M.2    Content, J.3
  • 31
    • 0033600160 scopus 로고    scopus 로고
    • Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1
    • DOI 10.1038/sj.onc.1202708
    • Kortylewski M, Heinrich PC, Mackiewicz A, Schniertshauer U, Klingmuller U, Nakajima K, Hirano T, Horn F and Behrmann I: Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells in STAT-dependent and involves up-regulation of the cyclin-dependent kinase inhibitor p27/KIP1. Oncogene 18: 3742-3753, 1999. (Pubitemid 29338507)
    • (1999) Oncogene , vol.18 , Issue.25 , pp. 3742-3753
    • Kortylewski, M.1    Heinrich, P.C.2    Mackiewicz, A.3    Schniertshauer, U.4    Klingmuller, U.5    Nakajima, K.6    Hirano, T.7    Horn, F.8    Behrmann, I.9
  • 33
    • 0027533943 scopus 로고
    • Interleukin-1 alpha and interleukin-6 act additively to inhibit growth of MCF-7 breast cancer cells in vitro
    • Danforth DN Jr., and Sgagias MK: Interleukin-1 alpha and interleukin-6 act additively to inhibit growth of MCF-7 breast cancer cells in vitro. Cancer Res 53: 1538-1545, 1993.
    • (1993) Cancer Res , vol.53 , pp. 1538-1545
    • Danforth Jr., D.N.1    Sgagias, M.K.2
  • 34
    • 0035893768 scopus 로고    scopus 로고
    • Autocrine production of interleukin-6 causes multidrug resistance in breast cancer cells
    • Conze D, Weiss L, Regan PS, Bhushan A, Weaver D, Johnson P and Rincon M: Autocrine production of interleukin-6 causes multidrug resistance in breast cancer cells. Cancer Res 61: 8851-8858, 2001.
    • (2001) Cancer Res , vol.61 , pp. 8851-8858
    • Conze, D.1    Weiss, L.2    Regan, P.S.3    Bhushan, A.4    Weaver, D.5    Johnson, P.6    Rincon, M.7
  • 35
    • 0036022483 scopus 로고    scopus 로고
    • The influence of inflammatory cytokines on estrogen production and cell proliferation in human breast cancer cells
    • Honma S, Shimodaira K, Shimizu Y, Tsuchiya N, Saito H, Yanaihara T and Okai T: The influence of inflammatory cytokines on estrogen production and cell proliferation in human breast cancer cells. Endocr J 49: 371-377, 2002. (Pubitemid 34832311)
    • (2002) Endocrine Journal , vol.49 , Issue.3 , pp. 371-377
    • Honma, S.1    Shimodaira, K.2    Shimizu, Y.3    Tsuchiya, N.4    Saito, H.5    Yanaihara, T.6    Okai, T.7
  • 36
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
    • DOI 10.1016/S1074-7613(00)80501-4
    • Fukada T, Hibi M, Yamanaka Y, Takahishi-Tezuka M, Fujitani Y, Yamaguchi T, Nakajima K and Hirano T: Two signals are necessary for cell proliferation induced by a cytokine receptor GP130: involvement of STAT3 in anti-apoptosis. Immunity 5: 449-460, 1996. (Pubitemid 26423473)
    • (1996) Immunity , vol.5 , Issue.5 , pp. 449-460
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3    Takahashi-Tezuka, M.4    Fujitani, Y.5    Yamaguchi, T.6    Nakajima, K.7    Hirano, T.8
  • 37
    • 0033526808 scopus 로고    scopus 로고
    • Molecular basis underlying functional pleiotropy of cytokines and growth factors
    • Hirano T: Molecular basis underlying functional pleiotropy of cytokines and growth factors. Biochem Biophys Res Commun 260: 303-308, 1999.
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 303-308
    • Hirano, T.1
  • 38
    • 0344441877 scopus 로고    scopus 로고
    • Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways
    • DOI 10.1038/sj.onc.1207084
    • Leu CM, Wong FH, Chang C, Huang SF and Hu CP: Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. Oncogene 22: 7809-7818, 2003. (Pubitemid 37485540)
    • (2003) Oncogene , vol.22 , Issue.49 , pp. 7809-7818
    • Leu, C.-M.1    Wong, F.-H.2    Chang, C.3    Huang, S.-F.4    Hu, C.-P.5
  • 40
    • 0036186450 scopus 로고    scopus 로고
    • STAT3, but not ERKs, mediates the IL-6-induced proliferation of renal cancer cells, ACHN and 769P
    • DOI 10.1046/j.1523-1755.2002.00206.x
    • Horiguchi A, Oya M, Marumo K and Murai M: STAT3, but not ERKs, mediates the IL-induced proliferation of renal cancer cells, ACHN and 769P. Kidney Int 61: 926-938, 2002. (Pubitemid 34175461)
    • (2002) Kidney International , vol.61 , Issue.3 , pp. 926-938
    • Horiguchi, A.1    Oya, M.2    Marumo, K.3    Murai, M.4
  • 42
    • 0035869433 scopus 로고    scopus 로고
    • Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability
    • DOI 10.1182/blood.V97.6.1679
    • Corada M, Liao F, Lindgren M, Lampugnani MG, Breviario F, Frank R, Muller WA, Hicklin DJ, Bohlen P and Dejana E: Monoclonal antibodies directed to different regions of vascular endothelial Cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability. Blood 97: 1679-1684, 2001. (Pubitemid 32217233)
    • (2001) Blood , vol.97 , Issue.6 , pp. 1679-1684
    • Corada, M.1    Liao, F.2    Lindgren, M.3    Lampugnani, M.G.4    Breviario, F.5    Frank, R.6    Muller, W.A.7    Hicklin, D.J.8    Bohlen, P.9    Dejana, E.10
  • 43
    • 0033937509 scopus 로고    scopus 로고
    • Reduction in serum IL-6 after vacination of breast cancer patients with tumour-associated antigens is related to estrogen receptor status
    • DOI 10.1006/cyto.1999.0591
    • Jiang, XP, Yang DC, Elliott RL and Head JF: Reduction in serum IL-6 after vaccination of breast cancer patients with tumor-associated antigens is related to estrogen receptor status. Cytokine 12: 458-465, 2000. (Pubitemid 30449843)
    • (2000) Cytokine , vol.12 , Issue.5 , pp. 458-465
    • Jiang, X.P.1    Yang, D.C.2    Elliott, R.L.3    Head, J.F.4
  • 44
    • 80051624497 scopus 로고    scopus 로고
    • All-trans-retinoic acid down-regulates interleukin-6 synthesis in human breast cancer
    • Jiang XP, Yang DC, Head JF and Elliott RL: All-trans-retinoic acid down-regulates interleukin-6 synthesis in human breast cancer. Proc Am Assoc Cancer Res 40: 63, 1999.
    • (1999) Proc Am Assoc Cancer Res , vol.40 , pp. 63
    • Jiang, X.P.1    Yang, D.C.2    Head, J.F.3    Elliott, R.L.4
  • 45
    • 80051633664 scopus 로고    scopus 로고
    • Vaccination of breast cancer patients with autologous tumor-associated antigens results in reduction of serum interleukin-6
    • Jiang XP, Yang DC, Head JF and Elliott RL: Vaccination of breast cancer patients with autologous tumor-associated antigens results in reduction of serum interleukin-6. Proc Am Assoc Cancer Res 39: 356, 1998.
    • (1998) Proc Am Assoc Cancer Res , vol.39 , pp. 356
    • Jiang, X.P.1    Yang, D.C.2    Head, J.F.3    Elliott, R.L.4
  • 46
    • 4244020503 scopus 로고    scopus 로고
    • Serum interleukin-6 (IL-6) concentration correlates with serum tumor marker CA15-3 concentration in breast cancer patients
    • Head JF, Jiang XP, Yang DC and Elliott RL: Serum interleukin-6 (IL-6) concentration correlates with serum tumor marker CA15-3 concentration in breast cancer patients. Proc Am Soc Clin Oncol 18: 630a, 1999.
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Head, J.F.1    Jiang, X.P.2    Yang, D.C.3    Elliott, R.L.4
  • 48
    • 77952077836 scopus 로고    scopus 로고
    • Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells
    • Saydmohammed M, Joseph D and Syed V: Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells. J Cell Biochem 110: 447-456, 2010.
    • (2010) J Cell Biochem , vol.110 , pp. 447-456
    • Saydmohammed, M.1    Joseph, D.2    Syed, V.3
  • 49
    • 56349157010 scopus 로고    scopus 로고
    • Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells
    • Park J, Ayyappan V, Bae EK, Lee C, Kim BS, Kim BK, Lee YY, Ahn KS and Yoon SS: Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells. Mol Oncol 2: 317-326, 2008.
    • (2008) Mol Oncol , vol.2 , pp. 317-326
    • Park, J.1    Ayyappan, V.2    Bae, E.K.3    Lee, C.4    Kim, B.S.5    Kim, B.K.6    Lee, Y.Y.7    Ahn, K.S.8    Yoon, S.S.9
  • 50
    • 60949087064 scopus 로고    scopus 로고
    • Suppress of interleukin-6 and -8 production in head and neck cancer cells with curcumin via inhibition of Ikappa beta kinase
    • Cohen AN, Veena MS, Srivatsan BS and Wang MB: Suppress of interleukin-6 and -8 production in head and neck cancer cells with curcumin via inhibition of Ikappa beta kinase. Arch Otolaryngol Head Neck Surg 135: 190-197, 2009.
    • (2009) Arch Otolaryngol Head Neck Surg , vol.135 , pp. 190-197
    • Cohen, A.N.1    Veena, M.S.2    Srivatsan, B.S.3    Wang, M.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.