-
1
-
-
0034077041
-
Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
-
A Abeliovich Y Schmitz I Fariñas D Choi-Lundberg WH Ho PE Castillo N Shinsky JM Verdugo M Armanini A Ryan M Hynes H Phillips D Sulzer A Rosenthal 2000 Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system Neuron 25 239 252 10707987 10.1016/S0896-6273(00) 80886-7 1:CAS:528:DC%2BD3cXhtVWrt74%3D (Pubitemid 30316525)
-
(2000)
Neuron
, vol.25
, Issue.1
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.-H.5
Castillo, P.E.6
Shinsky, N.7
Garcia Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
2
-
-
33644954146
-
Amino acid sequence motifs and mechanistic features of the membrane translocation of alpha-synuclein
-
16524375 10.1111/j.1471-4159.2006.03731.x 1:CAS:528:DC%2BD28Xjslarsbw%3D
-
KJ Ahn SR Paik KC Chung J Kim 2006 Amino acid sequence motifs and mechanistic features of the membrane translocation of alpha-synuclein J Neurochem 97 265 279 16524375 10.1111/j.1471-4159.2006.03731.x 1:CAS:528:DC%2BD28Xjslarsbw%3D
-
(2006)
J Neurochem
, vol.97
, pp. 265-279
-
-
Ahn, K.J.1
Paik, S.R.2
Chung, K.C.3
Kim, J.4
-
3
-
-
0037127216
-
Tubulin seeds α-synuclein fibril formation
-
DOI 10.1074/jbc.M102981200
-
MA Alim MS Hossain K Arima K Takeda Y Izumiyama M Nakamura H Kaji T Shinoda S Hisanaga K Uéda 2002 Tubulin seeds alpha-synuclein fibril formation J Biol Chem 277 2112 2117 11698390 10.1074/jbc.M102981200 1:CAS:528:DC%2BD38XosFelsw%3D%3D (Pubitemid 34968795)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.3
, pp. 2112-2117
-
-
Alim, M.A.1
Hossain, M.S.2
Arima, K.3
Takeda, K.4
Izumiyama, Y.5
Nakamura, M.6
Kaji, H.7
Shinoda, T.8
Hisanaga, S.9
Ueda, K.10
-
4
-
-
4644249092
-
Demonstration of a role for α-synuclein as a functional microtubule-associated protein
-
MA Alim QL Ma K Takeda T Aizawa M Matsubara M Nakamura A Asada T Saito H Kaji M Yoshii S Hisanaga K Uéda 2004 Demonstration of a role for alpha-synuclein as a functional microtubule-associated protein J Alzheimers Dis 6 435 442 15345814 (Pubitemid 39287257)
-
(2004)
Journal of Alzheimer's Disease
, vol.6
, Issue.4
, pp. 435-442
-
-
Alim, M.A.1
Ma, Q.-L.2
Takeda, K.3
Aizawa, T.4
Matsubara, M.5
Nakamura, M.6
Asada, A.7
Saito, T.8
Kaji, H.9
Yoshii, M.10
Hisanaga, S.11
Ueda, K.12
-
5
-
-
0344808098
-
Immunoelectron-microscopic demonstration of NACP/α-synuclein- epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies
-
DOI 10.1016/S0006-8993(98)00734-3, PII S0006899398007343
-
K Arima K Uéda N Sunohara S Hirai Y Izumiyama H Tonozuka-Uehara M Kawai 1998 Immunoelectron-microscopic demonstration of NACP/alpha-synuclein- epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies Brain Res 808 93 100 9795161 10.1016/S0006-8993(98) 00734-3 1:CAS:528:DyaK1cXms1Srtbc%3D (Pubitemid 29003204)
-
(1998)
Brain Research
, vol.808
, Issue.1
, pp. 93-100
-
-
Arima, K.1
Ueda, K.2
Sunohara, N.3
Hirai, S.4
Izumiyama, Y.5
Tonozuka-Uehara, H.6
Kawai, M.7
-
6
-
-
0031715398
-
NACP/α-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy
-
Arima K, Uéda K, Sunohara N, Arakawa K, Hirai S, Nakamura M, Tonozuka-Uehara H, Kawai M (1998b) NACP/α-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy. Acta Neuropathol 96:439-444
-
(1998)
Acta Neuropathol
, vol.96
, pp. 439-444
-
-
Arima K, U.1
-
7
-
-
77953575526
-
Oligomeric alpha-synuclein and its role in neuronal death
-
20209636 1:CAS:528:DC%2BC3cXkvFegtLc%3D
-
DR Brown 2010 Oligomeric alpha-synuclein and its role in neuronal death IUBMB Life 62 334 339 20209636 1:CAS:528:DC%2BC3cXkvFegtLc%3D
-
(2010)
IUBMB Life
, vol.62
, pp. 334-339
-
-
Brown, D.R.1
-
8
-
-
0038054286
-
A structural and functional role for 11-mer repeats in α-synuclein and other exchangeable lipid binding proteins
-
DOI 10.1016/S0022-2836(03)00520-5
-
RJ Bussell D Eliezer 2003 A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins J Mol Biol 329 763 778 12787676 10.1016/S0022-2836(03)00520-5 1:CAS:528: DC%2BD3sXkt1Gktr4%3D (Pubitemid 36629369)
-
(2003)
Journal of Molecular Biology
, vol.329
, Issue.4
, pp. 763-778
-
-
Bussell Jr., R.1
Eliezer, D.2
-
9
-
-
0026781572
-
A novel N18TG2 × mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin
-
1356145 1:CAS:528:DyaK38Xmt12ms7g%3D
-
GD Crawford Jr WD Le RG Smith WJ Xie E Stefani SH Appel 1992 A novel N18TG2 × mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin J Neurosci 12 3392 3398 1356145 1:CAS:528:DyaK38Xmt12ms7g%3D
-
(1992)
J Neurosci
, vol.12
, pp. 3392-3398
-
-
Crawford Jr., G.D.1
Le, W.D.2
Smith, R.G.3
Xie, W.J.4
Stefani, E.5
Appel, S.H.6
-
10
-
-
70349895344
-
Role of synucleins in Alzheimer's disease
-
19551456 10.1007/s12640-009-9073-6 1:CAS:528:DC%2BD1MXhtFOkt7fM
-
L Crews I Tsigelny M Hashimoto E Masliah 2009 Role of synucleins in Alzheimer's disease Neurotox Res 16 306 317 19551456 10.1007/s12640-009-9073-6 1:CAS:528:DC%2BD1MXhtFOkt7fM
-
(2009)
Neurotox Res
, vol.16
, pp. 306-317
-
-
Crews, L.1
Tsigelny, I.2
Hashimoto, M.3
Masliah, E.4
-
11
-
-
0035069311
-
Differential expression and distribution of α-, β-, and γ-synuclein in the developing human substantia nigra
-
DOI 10.1006/exnr.2000.7615
-
JE Galvin TM Schuck VM Lee JQ Trojanowski 2001 Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra Exp Neurol 168 347 355 11259122 10.1006/exnr.2000.7615 1:CAS:528:DC%2BD3MXhvFKjsb8%3D (Pubitemid 32289770)
-
(2001)
Experimental Neurology
, vol.168
, Issue.2
, pp. 347-355
-
-
Galvin, J.E.1
Schuck, T.M.2
Lee, V.M.-Y.3
Trojanowski, J.Q.4
-
12
-
-
0036150971
-
The synucleins
-
10.1186/gb-2001-3-1-reviews3002
-
JM George 2001 The synucleins Genome Biol 3 1 6 10.1186/gb-2001-3-1- reviews3002
-
(2001)
Genome Biol
, vol.3
, pp. 1-6
-
-
George, J.M.1
-
13
-
-
0035901724
-
Testosterone regulates α-synuclein mRNA in the avian song system
-
VN Hartman MA Miller DF Clayton WC Liu DE Kroodsma EA Brenowitz 2001 Testosterone regulates alpha-synuclein mRNA in the avian song system Neuroreport 12 943 946 11303765 10.1097/00001756-200104170-00016 1:CAS:528: DC%2BD3MXjtVWhu7Y%3D (Pubitemid 32281452)
-
(2001)
NeuroReport
, vol.12
, Issue.5
, pp. 943-946
-
-
Hartman, V.N.1
Miller, M.A.2
Clayton, D.F.3
Liu, W.-C.4
Kroodsma, D.E.5
Brenowitz, E.A.6
-
15
-
-
0033980068
-
α-synuclein is expressed in a variety of brain tumors showing neuronal differentiation
-
M Kawashima SO Suzuki K Doh-ura T Iwaki 2000 alpha-Synuclein is expressed in a variety of brain tumors showing neuronal differentiation Acta Neuropathol 99 154 160 10672322 10.1007/PL00007419 1:CAS:528:DC%2BD3cXosVSn (Pubitemid 30093422)
-
(2000)
Acta Neuropathologica
, vol.99
, Issue.2
, pp. 154-160
-
-
Kawashima, M.1
Suzuki, S.O.2
Doh-Ura, K.3
Iwaki, T.4
-
16
-
-
0037137224
-
Structural and functional implications of C-terminal regions of α-synuclein
-
DOI 10.1021/bi026284c
-
TD Kim SR Paik CH Yang 2002 Structural and functional implications of C-terminal regions of alpha-synuclein Biochemistry 41 13782 13790 12427041 10.1021/bi026284c 1:CAS:528:DC%2BD38XotVWqsL8%3D (Pubitemid 35332716)
-
(2002)
Biochemistry
, vol.41
, Issue.46
, pp. 13782-13790
-
-
Kim, T.D.1
Paik, S.R.2
Yang, C.-H.3
-
17
-
-
0029913602
-
A human B-box-binding protein downregulated in adenovirus 5-transformed human cells
-
DOI 10.1016/0014-5793(96)00353-5
-
AV Kropotov NV Tomilin 1996 A human B-box-binding protein downregulated in adenovirus 5-transformed human cells FEBS Lett 386 43 46 8635600 10.1016/0014-5793(96)00353-5 1:CAS:528:DyaK28XjtFejsLg%3D (Pubitemid 26143797)
-
(1996)
FEBS Letters
, vol.386
, Issue.1
, pp. 43-46
-
-
Kropotov, A.V.1
Tomilin, N.V.2
-
18
-
-
0042886045
-
Cell cycle aberrations by α-synuclein over-expression and cyclin B immunoreactivity in Lewy bodies
-
DOI 10.1016/S0197-4580(02)00196-3, PII S0197458002001963
-
SS Lee YM Kim E Junn G Lee KH Park M Tanaka RD Ronchetti MM Quezado MM Mouradian 2003 Cell cycle aberrations by alpha-synuclein over-expression and cyclin B immunoreactivity in Lewy bodies Neurobiol Aging 24 687 696 12885576 10.1016/S0197-4580(02)00196-3 1:CAS:528:DC%2BD3sXls1Omtbk%3D (Pubitemid 37303989)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.5
, pp. 687-696
-
-
Lee, S.S.1
Kim, Y.M.2
Junn, E.3
Lee, G.4
Park, K.-H.5
Tanaka, M.6
Ronchetti, R.D.7
Quezado, M.M.8
Mouradian, M.M.9
-
19
-
-
44749083979
-
Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein
-
18291704 10.1016/j.biocel.2008.01.017 1:CAS:528:DC%2BD1cXnsF2mtrk%3D
-
HJ Lee JE Suk EJ Bae JH Lee SR Paik SJ Lee 2008 Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein Int J Biochem Cell Biol 40 1835 1849 18291704 10.1016/j.biocel.2008.01.017 1:CAS:528: DC%2BD1cXnsF2mtrk%3D
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1835-1849
-
-
Lee, H.J.1
Suk, J.E.2
Bae, E.J.3
Lee, J.H.4
Paik, S.R.5
Lee, S.J.6
-
20
-
-
0037954360
-
Alpha-synuclein aggregation and neurodegenerative diseases
-
12719631 1:CAS:528:DC%2BD3sXjt1Gis70%3D
-
QL Ma P Chan M Yoshii K Uéda 2003 Alpha-synuclein aggregation and neurodegenerative diseases J Alzheimers Dis 5 139 148 12719631 1:CAS:528:DC%2BD3sXjt1Gis70%3D
-
(2003)
J Alzheimers Dis
, vol.5
, pp. 139-148
-
-
Ma, Q.L.1
Chan, P.2
Yoshii, M.3
Uéda, K.4
-
21
-
-
33748584602
-
Interaction between Aβ peptide and α synuclein: Molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease
-
DOI 10.1007/s11064-006-9140-9
-
PK Mandal JW Pettegrew E Masliah RL Hamilton R Mandal 2006 Interaction between Abeta peptide and alpha synuclein: molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease Neurochem Res 31 1153 1162 16947080 10.1007/s11064-006-9140-9 1:CAS:528:DC%2BD28XptlSmtLs%3D (Pubitemid 44379676)
-
(2006)
Neurochemical Research
, vol.31
, Issue.9
, pp. 1153-1162
-
-
Mandal, P.K.1
Pettegrew, J.W.2
Masliah, E.3
Hamilton, R.L.4
Mandal, R.5
-
23
-
-
63049097996
-
Positioning cytokinesis
-
19299557 10.1101/gad.1772009 1:CAS:528:DC%2BD1MXktVWltrg%3D
-
S Oliferenko TG Chew MK Balasubramanian 2009 Positioning cytokinesis Genes Dev 23 660 674 19299557 10.1101/gad.1772009 1:CAS:528:DC%2BD1MXktVWltrg%3D
-
(2009)
Genes Dev
, vol.23
, pp. 660-674
-
-
Oliferenko, S.1
Chew, T.G.2
Balasubramanian, M.K.3
-
24
-
-
0037449782
-
2 arrest and down-regulation of Stathmin and AIM-1 expression in response to genotoxic stress
-
DOI 10.1074/jbc.M210327200
-
S Polager D Ginsberg 2003 E2F mediates sustained G2 arrest and down-regulation of Stathmin and AIM-1 expression in response to genotoxic stress J Biol Chem 278 1443 1449 12446714 10.1074/jbc.M210327200 1:CAS:528: DC%2BD3sXisFyisg%3D%3D (Pubitemid 36801369)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.3
, pp. 1443-1449
-
-
Polager, S.1
Ginsberg, D.2
-
26
-
-
0031910093
-
Aggregation of neurofilament and α-synuclein proteins in Lewy bodies: Implications for the pathogenesis of Parkinson disease and Lewy body dementia
-
DOI 10.1001/archneur.55.2.151
-
J Trojanowski V Lee 1998 Aggregation of neurofilament and α-syn proteins in Lewy bodies: implications for pathogenesis of Parkinson disease and Lewy body dementia Arch Neurol 55 151 152 9482355 10.1001/archneur.55.2.151 1:STN:280:DyaK1c7ktFCmuw%3D%3D (Pubitemid 28110056)
-
(1998)
Archives of Neurology
, vol.55
, Issue.2
, pp. 151-152
-
-
Trojanowski, J.Q.1
Lee, V.M.-Y.2
-
27
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
DOI 10.1073/pnas.90.23.11282
-
K Uéda H Fukushima E Masliah Y Xia A Iwai M Yoshimoto DAC Otero J Kondo Y Ihara T Saitoh 1993 Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease Proc Natl Acad Sci USA 90 11282 11286 8248242 10.1073/pnas.90.23.11282 (Pubitemid 23354413)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.A.C.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
28
-
-
0026775358
-
Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts
-
1387400 10.1083/jcb.118.5.1097 1:CAS:528:DyaK38XkvVGgtbo%3D
-
F Verde M Dogterom E Stelzer E Karsenti S Leibler 1992 Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts J Cell Biol 118 5 1097 1108 1387400 10.1083/jcb.118.5.1097 1:CAS:528:DyaK38XkvVGgtbo%3D
-
(1992)
J Cell Biol
, vol.118
, Issue.5
, pp. 1097-1108
-
-
Verde, F.1
Dogterom, M.2
Stelzer, E.3
Karsenti, E.4
Leibler, S.5
-
29
-
-
68749118423
-
Neural cell cycle dysregulation and central nervous system diseases
-
19619927 10.1016/j.pneurobio.2009.01.007 1:CAS:528:DC%2BD1MXhtVehurrN
-
W Wang B Bu M Xie M Zhang Z Yu D Tao 2009 Neural cell cycle dysregulation and central nervous system diseases Prog Neurobiol 89 1 17 19619927 10.1016/j.pneurobio.2009.01.007 1:CAS:528:DC%2BD1MXhtVehurrN
-
(2009)
Prog Neurobiol
, vol.89
, pp. 1-17
-
-
Wang, W.1
Bu, B.2
Xie, M.3
Zhang, M.4
Yu, Z.5
Tao, D.6
-
30
-
-
4043107784
-
Inhibition of tyrosine hydroxylase expression in α-synuclein- transfected dopaminergic neuronal cells
-
DOI 10.1016/j.neulet.2004.05.118, PII S0304394004006755
-
S Yu X Zuo Y Li C Zhang M Zhou YA Zhang K Uéda P Chan 2004 Inhibition of tyrosine hydroxylase expression in alpha-synuclein-transfected dopaminergic neuronal cells Neurosci Lett 367 34 39 15308292 10.1016/j.neulet.2004.05.118 1:CAS:528:DC%2BD2cXmslelurs%3D (Pubitemid 39078779)
-
(2004)
Neuroscience Letters
, vol.367
, Issue.1
, pp. 34-39
-
-
Yu, S.1
Zuo, X.2
Li, Y.3
Zhang, C.4
Zhou, M.5
Zhang, Y.A.6
Ueda, K.7
Chan, P.8
-
31
-
-
33847649977
-
Extensive nuclear localization of α-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody
-
DOI 10.1016/j.neuroscience.2006.12.028, PII S0306452206016915
-
S Yu X Li G Liu J Han C Zhang Y Li S Xu C Liu Y Gao H Yang K Uéda P Chan 2007 Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody Neuroscience 145 539 555 17275196 10.1016/j.neuroscience.2006.12.028 1:CAS:528:DC%2BD2sXivVSjtLk%3D (Pubitemid 46350815)
-
(2007)
Neuroscience
, vol.145
, Issue.2
, pp. 539-555
-
-
Yu, S.1
Li, X.2
Liu, G.3
Han, J.4
Zhang, C.5
Li, Y.6
Xu, S.7
Liu, C.8
Gao, Y.9
Yang, H.10
Ueda, K.11
Chan, P.12
-
32
-
-
65749095912
-
Intracellular targeting and clearance of oligomeric alpha-synuclein alleviates toxicity in mammalian cells
-
19394405 10.1016/j.neulet.2009.04.046 1:CAS:528:DC%2BD1MXmsFyhsbk%3D
-
B Yuan MR Sierks 2009 Intracellular targeting and clearance of oligomeric alpha-synuclein alleviates toxicity in mammalian cells Neurosci Lett 459 16 18 19394405 10.1016/j.neulet.2009.04.046 1:CAS:528:DC%2BD1MXmsFyhsbk%3D
-
(2009)
Neurosci Lett
, vol.459
, pp. 16-18
-
-
Yuan, B.1
Sierks, M.R.2
|