Carbohydrate provision in the era of tight glucose control

Current Gastroenterology Reports

Volumn 13, Issue 4, 2011, Pages 388-394

  Miller, Keith R ^a   Lawson, Christy M ^b   Smith, Vance L ^c   Harbrecht, Brian G ^a  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

Carbohydrate provision; Enteral nutrition; Glucose control; Glycemic control; Intensive insulin therapy; Parenteral nutrition

Indexed keywords

ADVANCED GLYCATION END PRODUCT; GLUCOSE; INSULIN; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

CALORIC INTAKE; CARBOHYDRATE INTAKE; CLINICAL PRACTICE; CRITICALLY ILL PATIENT; CYTOKINE PRODUCTION; ENTERIC FEEDING; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INNATE IMMUNITY; INSULIN TREATMENT; INTENSIVE CARE; INTENSIVE CARE UNIT; MORBIDITY; MORTALITY; NUTRITIONAL SUPPORT; PARENTERAL NUTRITION; PATIENT CARE; PATIENT MONITORING; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; TREATMENT OUTCOME;

DIETARY CARBOHYDRATES; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIA; INTENSIVE CARE UNITS; NUTRITIONAL SUPPORT;

EID: 80051583187     PISSN: 15228037     EISSN: 1534312X     Source Type: Journal    
DOI: 10.1007/s11894-011-0204-x     Document Type: Review

References (46)

1. G Van den Berghe P Wouters F Weekers, et al. 2001 Intensive insulin therapy in the critically ill patients N Engl J Med 345 1359 1367 11794168 10.1056/NEJMoa011300
2. G Van den Berghe A Wilmer G Hermans, et al. 2006 Intensive insulin therapy in the medical ICU N Engl J Med 354 449 461 16452557 10.1056/NEJMoa052521 (Pubitemid 43200296)
3. FW Pavy 1900 Fundamental Points Connected with the Pathology of Diabetes Mellitus Br Med J 2 2083 1558 1561 20759298 10.1136/bmj.2.2083.1558 1:STN:280:DC%2BC3MzitVGltw%3D%3D
4. M Turina DE Fry HC Polk Jr 2005 Acute hyperglycemia and the innate immune system: clinical, cellular, and molecular aspects Crit Care Med 33 7 1624 33 16003073 10.1097/01.CCM.0000170106.61978.D8 (Pubitemid 40980623)
5. JC Pickup GD Chusney SM Thomas D Burt 2000 Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes Life Sci 67 3 291 300 10983873 10.1016/S0024-3205(00)00622-6 1:CAS:528: DC%2BD3cXksVOmt74%3D (Pubitemid 30413937)
6. RJ Esper JO Vilariño RA Machado A Paragano 2008 Endothelial dysfunction in normal and abnormal glucose metabolism Adv Cardiol 45 17 43 18230954 10.1159/000115120 1:CAS:528:DC%2BD1MXhsl2jsrc%3D
7. NT Mowery AK May BC Collier, et al. 2010 Glucose metabolism, not obesity, predicts mortality in critically ill surgical patients Am Surg 76 12 1377 83 21265352
8. LH Thompson HT Kim Y Ma, et al. 2008 Acute, muscle-type specific insulin resistance following injury Mol Med 14 11-12 715 723 19009015 1:CAS:528:DC%2BD1cXhsVOgu7vE
9. N Ahmed A Dávalos N Eriksson, et al. 2010 SITS Investigators: Association of admission blood glucose and outcome in patients treated with intravenous thrombolysis: results from the Safe Implementation of Treatments in Stroke International Stroke Thrombolysis Register (SITS-ISTR) Arch Neurol 67 9 1123 30 20837858 10.1001/archneurol.2010.210
10. V Brix-Christensen SK Andersen R Andersen, et al. 2004 Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model Anesthesiology 100 4 861 70 15087621 10.1097/00000542-200404000-00016 1:CAS:528:DC%2BD2cXjs1ahurc%3D (Pubitemid 38392573)
11. T Albacker G Carvalho T Schricker K Lachapelle 2008 High-dose insulin therapy attenuates systemic inflammatory response in coronary artery bypass grafting patients Ann Thorac Surg 86 1 20 7 18573392 10.1016/j.athoracsur.2008. 03.046
12. YM Arabi OC Dabbagh HM Tamin, et al. 2008 Intensive versus conventional insulin therapy: a randomized controlled trial in medical and surgical critically ill patients Crit Care Med 36 190 7 10.1097/CCM.0b013e31818f21aa
13. FM Brunkhorst C Engel F Bloos, et al. 2008 Intensive insulin therapy and pentastarch resuscitation in severe sepsis N Engl J Med 358 125 39 18184958 10.1056/NEJMoa070716 1:CAS:528:DC%2BD1cXltFWltQ%3D%3D
14. GDC De La Rosa JH Donado AH Restrepo, et al. 2008 Strict glycaemic control in patients hospitalized in a mixed medical and surgical intensive care unit: a randomized clinical trial Crit Care 12 5 R120 10.1186/cc7017
15. JC Preiser P Devos S Ruiz-Santana, et al. 2009 A prospective randomized multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study Intensive Care Med 35 1738 48 19636533 10.1007/s00134-009-1585-2 1:CAS:528:DC%2BD1MXhtFOiu7fE
16. JS Krinsley 2004 Effect of an intensive glucose management protocol on the mortality of critically ill adult patients Mayo Clin Pro 79 992 1000 10.4065/79.8.992 (Pubitemid 39007018)
17. P Lecomte L Foubert F Nobels, et al. 2008 Dynamictight glycemic control during and after cardiac surgery is effective, feasible and safe AneshAnalg 107 51 58 10.1213/ane.0b013e318172c557 1:CAS:528:DC%2BD1cXns1OksL4%3D
18. P Lecomte B Van Vlem J Coddens, et al. 2008 Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients Crit Care 12 R154 19055829 10.1186/cc7145
19. AP Furnary DB Cheek SC Holmes, et al. 2006 Achieving right glycemic control in the operating room: lessons learned from 12 years in the trenches of a paradigm shift in anesthetic care Semin Thorac Cardiovasc 18 339 345 10.1053/j.semtcvs.2007.01.004 (Pubitemid 46464519)
20. S Finfer DR Chittock SY Su, et al. 2009 Intensive versus Conventional Glucose Control in Critically Ill Patients N Engl J Med 360 1283 1297 19318384 10.1056/NEJMoa0810625 This large prospective RTC (6000 patients) conducted in a heterogenous ICU population demonstrated significantly higher rates of hypoglycemia and 90-day mortality utilizing IIT protocols to maintain glucose levels <108 mg/dL
21. TM Vriesendorp JH DeVries S van Santen, et al. 2006 Evaluation of short- term consequences of hypoglycemia in an intensive care unit Crit Care Med 34 2714 2718 16943734 10.1097/01.CCM.0000241155.36689.91 1:CAS:528: DC%2BD28XhtV2rsrbP (Pubitemid 44610935)
22. M Egi R Bellomo E Stachowski, et al. 2010 Hypoglycemia and outcome in critical illness Mayo Clin Proc 85 3 217 224 20176928 10.4065/mcp.2009.0394
23. S Dotson R Freeman HJ Failing GK Adler 2008 Hypoglycemia increases serum interleuldn-6 levels in healthy men and women Diabetes Care 31 1222 1223 18332163 10.2337/dc07-2243 1:CAS:528:DC%2BD1cXotVantrY%3D
24. ME Keller-Wood J Shinsako MF Dallman 1983 Inhibition of the adreno-corticotropin and corticosteroid responses to hypoglycemia after prior stress Endocrinology 113 491 496 6307641 10.1210/endo-113-2-491 1:CAS:528:DyaL3sXkvF2lur0%3D (Pubitemid 13048936)
25. G Dieguez N Fernandez JL Garcia, et al. 1997 Role of nitric oxide in the effects of hypoglycemia on the cerebral circulation in awake goats Eur J Pharmacol 330 185 193 9253952 10.1016/S0014-2999(97)00181-7 1:CAS:528: DyaK2sXkt1Shtr0%3D (Pubitemid 27296721)
26. M Egi R Bellomo 2009 Reducing Glycemic variability in intensive care unit patients: a new therapeutic target? J Diab Sci Tech 3 6 1302 1308
27. SM Bagshaw R Bellomo MJ Jacka, et al. 2009 The impact of early hypoglycemia and blood glucose variability on outcome in critical illness Crit Care 13 3 1 10 10.1186/cc7921 Retrospective review of 66,000 patients demonstrated the incidence of blood glucose variability and hypoglycemia in the ICU (13%) and their value as independent predictors of mortality
28. G Van den Berghe M Schetz D Vlasselaers, et al. 2009 Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target? J ClinEndocrinolMetab 94 9 3163 3170
29. PE Marik JC Preiser 2010 Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis Chest 137 3 544 51 20018803 10.1378/chest.09-1737 1:CAS:528:DC%2BC3cXksVyku78%3D Epub 2009 Dec 16. Meta-analytic techniques applied to seven PRCTs including 11,425 patients demonstrated significantly higher hypoglycemic episodes when utilizing IIT protocols and no change in mortality. More interestingly, a relationship between treatment effect and the use of PN was demonstrated, suggesting a possible explanation for the differences observed in the major trials
30. RM Waeschle O Moerer R Hilgers, et al. 2008 The impact of the severity of sepsis on the risk of hypoglycemia and glycemic variability Crit Care 12 R129 18939991 10.1186/cc7097
31. JS Krinsley 2008 The severity of sepsis: yet another factor influencing glycemic control Crit Care 12 194 19040779 10.1186/cc7111
32. S Eslami NF de Keizer E de Jonge, et al. 2008 A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset Crit Care 12 6 R139 19014427 10.1186/cc7114 Epub 2008 Nov 11. Review
33. S Kanji J Buffie B Hutton, et al. 2005 Reliability of point-of-care testing for glucose measurement in critically ill adults Crit Care Med 33 12 2778 85 16352960 10.1097/01.CCM.0000189939.10881.60 (Pubitemid 41816412)
34. S Villet R Chiolero M Bollman, et al. 2005 Negative impact of hypocaloric feeding and energy balance on clinical outcomes in ICU patients Clin Nutr 24 502 509 15899538 10.1016/j.clnu.2005.03.006 (Pubitemid 41051903)
35. Brady M, Kinn S, Stuart P: (2003) Preoperative fasting for adults to prevent perioperative complications. Cochrane Database Syst Rev (4): CD004423. no further risk of aspiration from allowing fluids.
36. SE Noblett DS Watson H Huong, et al. 2006 Pre-operative oral carbohydrate loading in colorectal surgery: a randomized controlled trial Colorectal Dis 8 7 563 9 16919107 10.1111/j.1463-1318.2006.00965.x 1:STN:280: DC%2BD28vpsVektQ%3D%3D (Pubitemid 44210107)
37. K Lassen M Soop J Nygren Enhanced Recovery After Surgery (ERAS) Group, et al. 2009 Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations Arch Surg 144 10 961 9 19841366 10.1001/archsurg.2009.170 Review
38. M Soop GL Carlson J Hopkinson, et al. 2004 Randomized clinical trial of the effects of immediate enteral nutrition on metabolic responses to major colorectal surgery in an enhanced recovery protocol Br J Surg 91 9 1138 45 15449264 10.1002/bjs.4642 1:STN:280:DC%2BD2cvnvFSlsA%3D%3D (Pubitemid 39179456)
39. KA Yuill RA Richardson HI Davidson, et al. 2005 The administration of an oral carbohydrate-containing fluid prior to major elective upper- gastrointestinal surgery preserves skeletal muscle mass postoperatively-a randomised clinical trial Clin Nutr 24 1 32 37 15681099 10.1016/j.clnu.2004.06. 009 1:CAS:528:DC%2BD2MXos1KjtQ%3D%3D
40. M Svanfeldt A Thorell J Hausel, et al. 2007 Randomized clinical trial of the effect of preoperative oral carbohydrate treatment on postoperative whole-body protein and glucose kinetics Br J Surg 94 11 1342 1350 17902094 10.1002/bjs.5919 1:CAS:528:DC%2BD2sXhsVGitbbM whole body protein maintained (Pubitemid 350144381)
41. A Mesejo JA Acosta C Ortega, et al. 2003 Comparison of a high-protein disease-specific enteral formula with a high-protein enteral formula in hyperglycemic critically ill patients Clin Nutr 22 3 295 305 12765670 10.1016/S0261-5614(02)00234-0 1:CAS:528:DC%2BD3sXjvFWmsrc%3D (Pubitemid 36701646)
42. SA McClave RG Martindale VW Vanek, et al. 2009 A.S.P.E.N. Board of Directors; American College of Critical Care Medicine; Society of Critical Care Medicine: Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) JPEN J Parenter Enteral Nutr 33 3 277 316 19398613 10.1177/0148607109335234 An excellent resource presenting guidelines supported by the SCCM and ASPEN regarding nutritional support in the critically ill patient
43. K Matsushima A Cook T Tyner, et al. 2010 Parenteral nutrition: a clear and present danger unabated by tight glucose control Am J Surg 200 3 386 90 20800717 10.1016/j.amjsurg.2009.10.023 1:CAS:528:DC%2BC3cXhtVyrtrvF Prospective cohort study demonstrating increased infectious complications (BSI, CRBSI) in patients receiving PN despite adequate glucose control
44. A Dan TC Jacques MJ O'Leary 2006 Enteral nutrition versus glucose-based or lipid-based parenteral nutrition and tight glycaemic control in critically ill patients Crit Care Resusc 8 4 283 8 17227262
45. LY Lin HC Lin PC Lee, et al. 2007 Hyperglycemia correlates with outcomes in patients receiving total parenteral nutrition Am J Med Sci 333 5 261 5 17505165 10.1097/MAJ.0b013e3180536b26 (Pubitemid 46787953)
46. M Hoekstra MA Schoorl IC van der Horst, et al. 2010 Computer-assisted glucose regulation during rapid step-wise increases of parenteral nutrition in critically ill patients: a proof of concept study JPEN J Parenter Enteral Nutr 34 5 549 53 20852185 10.1177/0148607110372390 1:CAS:528:DC%2BC3cXhtlWhsb7E