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Volumn 32, Issue 2, 2011, Pages 201-211

Bee venom induced cytogenetic damage and decreased cell viability in human white blood cells after treatment in vitro: A multi-biomarker approach

Author keywords

Apoptosis; Bee venom; Cytogenotoxicity; Human lymphocytes; Necrosis; Reactive oxygen species

Indexed keywords

BEE VENOM;

EID: 80051582297     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2011.05.004     Document Type: Article
Times cited : (25)

References (59)
  • 2
    • 0026490802 scopus 로고
    • Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood
    • DeForge L.E., Fantone J.C., Kenney J.S., Remick D.G. Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood. J. Clin. Invest. 1992, 90:2123-2129.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2123-2129
    • DeForge, L.E.1    Fantone, J.C.2    Kenney, J.S.3    Remick, D.G.4
  • 3
    • 0025217893 scopus 로고
    • The actions of melittin on membranes
    • Dempsey C.E. The actions of melittin on membranes. Biochim. Biophys. Acta 1990, 1031:143-161.
    • (1990) Biochim. Biophys. Acta , vol.1031 , pp. 143-161
    • Dempsey, C.E.1
  • 4
    • 0002230857 scopus 로고
    • Morphological and biochemical assays of apoptosis
    • John Willey & Sons, New York, J.E. Coligan, A.M. Kruisbeal (Eds.)
    • Duke R.C., Cohen J.J. Morphological and biochemical assays of apoptosis. Current Protocols in Immunology 1992, 1-3. John Willey & Sons, New York. J.E. Coligan, A.M. Kruisbeal (Eds.).
    • (1992) Current Protocols in Immunology , pp. 1-3
    • Duke, R.C.1    Cohen, J.J.2
  • 5
    • 0037427878 scopus 로고    scopus 로고
    • HUMN project: detailed description of scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures
    • Fenech M., Chang W.P., Kirsch-Volders M., Holland N., Bonassi S., Zeiger E. HUMN project: detailed description of scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat. Res. 2003, 534:65-75.
    • (2003) Mutat. Res. , vol.534 , pp. 65-75
    • Fenech, M.1    Chang, W.P.2    Kirsch-Volders, M.3    Holland, N.4    Bonassi, S.5    Zeiger, E.6
  • 6
    • 0021987630 scopus 로고
    • Measurement of micronuclei in lymphocytes
    • Fenech M., Morley A.A. Measurement of micronuclei in lymphocytes. Mutat. Res. 1985, 147:29-36.
    • (1985) Mutat. Res. , vol.147 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 7
    • 33747335092 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay evolves into a " cytome" assay of chromosomal instability, mitotic dysfunction and cell death
    • Fenech M. Cytokinesis-block micronucleus assay evolves into a " cytome" assay of chromosomal instability, mitotic dysfunction and cell death. Mutat. Res. 2006, 600:58-66.
    • (2006) Mutat. Res. , vol.600 , pp. 58-66
    • Fenech, M.1
  • 8
    • 0027254408 scopus 로고
    • Possible mechanisms of action of cobra snake venom cardiotoxins and bee venom melittin
    • Fletcher J.E., Jiang M.S. Possible mechanisms of action of cobra snake venom cardiotoxins and bee venom melittin. Toxicon 1993, 31:669-695.
    • (1993) Toxicon , vol.31 , pp. 669-695
    • Fletcher, J.E.1    Jiang, M.S.2
  • 9
    • 47649103928 scopus 로고    scopus 로고
    • Genotoxic potential of bee venom (Apis mellifera) on human peripheral blood lymphocytes in vitro using single cell gel electrophoresis assay
    • Gajski G., Garaj-Vrhovac V. Genotoxic potential of bee venom (Apis mellifera) on human peripheral blood lymphocytes in vitro using single cell gel electrophoresis assay. J. Environ. Sci. Health A: Tox. Hazard. Subst. Environ. Eng. 2008, 43:1279-1287.
    • (2008) J. Environ. Sci. Health A: Tox. Hazard. Subst. Environ. Eng. , vol.43 , pp. 1279-1287
    • Gajski, G.1    Garaj-Vrhovac, V.2
  • 10
    • 48549084307 scopus 로고    scopus 로고
    • Cytogenetic status and oxidative DNA-damage induced by atorvastatin in human peripheral blood lymphocytes: standard and Fpg-modified comet assay
    • Gajski G., Garaj-Vrhovac V., Oreščanin V. Cytogenetic status and oxidative DNA-damage induced by atorvastatin in human peripheral blood lymphocytes: standard and Fpg-modified comet assay. Toxicol. Appl. Pharmacol. 2008, 231:85-93.
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , pp. 85-93
    • Gajski, G.1    Garaj-Vrhovac, V.2    Oreščanin, V.3
  • 11
    • 68649114545 scopus 로고    scopus 로고
    • Radioprotective effects of honeybee venom (Apis mellifera) against 915-MHz microwave radiation-induced DNA damage in Wistar rat lymphocytes: in vitro study
    • Gajski G., Garaj-Vrhovac V. Radioprotective effects of honeybee venom (Apis mellifera) against 915-MHz microwave radiation-induced DNA damage in Wistar rat lymphocytes: in vitro study. Int. J. Toxicol. 2009, 28:88-98.
    • (2009) Int. J. Toxicol. , vol.28 , pp. 88-98
    • Gajski, G.1    Garaj-Vrhovac, V.2
  • 12
    • 80051593257 scopus 로고    scopus 로고
    • Bee venom and melittin are cytotoxic against different types of tumor and non-tumor cell lines in vitro
    • Gajski G., Čimbora-Zovko T., Osmak M., Garaj-Vrhovac V. Bee venom and melittin are cytotoxic against different types of tumor and non-tumor cell lines in vitro. Canc. Res. J. 2011, 4:159-174.
    • (2011) Canc. Res. J. , vol.4 , pp. 159-174
    • Gajski, G.1    Čimbora-Zovko, T.2    Osmak, M.3    Garaj-Vrhovac, V.4
  • 13
    • 54749118494 scopus 로고    scopus 로고
    • Efficacy of HUMN criteria for scoring the micronucleus assay in human lymphocytes exposed to a low concentration of p,p′-DDT
    • Garaj-Vrhovac V., Gajski G., Ravlić S. Efficacy of HUMN criteria for scoring the micronucleus assay in human lymphocytes exposed to a low concentration of p,p′-DDT. Braz. J. Med. Biol. Res. 2008, 41:473-476.
    • (2008) Braz. J. Med. Biol. Res. , vol.41 , pp. 473-476
    • Garaj-Vrhovac, V.1    Gajski, G.2    Ravlić, S.3
  • 14
    • 63849301135 scopus 로고    scopus 로고
    • Evaluation of the cytogenetic status of human lymphocytes after exposure to a high concentration of bee venom in vitro
    • Garaj-Vrhovac V., Gajski G. Evaluation of the cytogenetic status of human lymphocytes after exposure to a high concentration of bee venom in vitro. Arh. Hig. Rada Toksikol. 2009, 60:27-34.
    • (2009) Arh. Hig. Rada Toksikol. , vol.60 , pp. 27-34
    • Garaj-Vrhovac, V.1    Gajski, G.2
  • 16
    • 0021438915 scopus 로고
    • Melittin and the 8-26 fragment. Differences in ionophoric properties as measured by monolayer method
    • Gevod V.S., Birdi K.S. Melittin and the 8-26 fragment. Differences in ionophoric properties as measured by monolayer method. Biophys. J. 1984, 45:1079-1083.
    • (1984) Biophys. J. , vol.45 , pp. 1079-1083
    • Gevod, V.S.1    Birdi, K.S.2
  • 17
    • 0015527253 scopus 로고
    • Bee and wasp venoms: the biochemistry and pharmacology of heir peptides and enzymes are reviewed
    • Habermann E. Bee and wasp venoms: the biochemistry and pharmacology of heir peptides and enzymes are reviewed. Science 1972, 177:314-322.
    • (1972) Science , vol.177 , pp. 314-322
    • Habermann, E.1
  • 18
    • 0031763876 scopus 로고    scopus 로고
    • From demons to darlings: drugs from venoms
    • Harvey A. From demons to darlings: drugs from venoms. Drug Discov. Today 1998, 3:531-532.
    • (1998) Drug Discov. Today , vol.3 , pp. 531-532
    • Harvey, A.1
  • 19
    • 20444497923 scopus 로고    scopus 로고
    • Bee venom induces apoptosis through caspase-3 activation in synovial fibroblasts of patients with rheumatoid arthritis
    • Hong S.J., Rim G.S., Yang H.I., Yin C.S., Koh H.G., Jang M.H., Kim C.J., Choe B.K., Chung J.H. Bee venom induces apoptosis through caspase-3 activation in synovial fibroblasts of patients with rheumatoid arthritis. Toxicon 2005, 46:39-45.
    • (2005) Toxicon , vol.46 , pp. 39-45
    • Hong, S.J.1    Rim, G.S.2    Yang, H.I.3    Yin, C.S.4    Koh, H.G.5    Jang, M.H.6    Kim, C.J.7    Choe, B.K.8    Chung, J.H.9
  • 20
    • 29944436034 scopus 로고    scopus 로고
    • Effect of polypeptides in bee venom on growth inhibition and apoptosis induction of the human hepatoma cell line SMMC-7721 in-vitro and Balb/c nude mice in-vivo
    • Hu H., Chen D., Li Y., Zhang X. Effect of polypeptides in bee venom on growth inhibition and apoptosis induction of the human hepatoma cell line SMMC-7721 in-vitro and Balb/c nude mice in-vivo. J. Pharm. Pharmacol. 2006, 58:83-89.
    • (2006) J. Pharm. Pharmacol. , vol.58 , pp. 83-89
    • Hu, H.1    Chen, D.2    Li, Y.3    Zhang, X.4
  • 24
    • 0037716618 scopus 로고    scopus 로고
    • Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299
    • Jang M.H., Shin M.C., Lim S., Han S.M., Park H.J., Shin I. Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299. J. Pharmacol. Sci. 2003, 91:95-104.
    • (2003) J. Pharmacol. Sci. , vol.91 , pp. 95-104
    • Jang, M.H.1    Shin, M.C.2    Lim, S.3    Han, S.M.4    Park, H.J.5    Shin, I.6
  • 25
    • 0036043862 scopus 로고    scopus 로고
    • The effect of whole bee venom on arthritis
    • Kang S.S., Pak S.C., Choi S.H. The effect of whole bee venom on arthritis. Am. J. Chin. Med. 2002, 30:73-80.
    • (2002) Am. J. Chin. Med. , vol.30 , pp. 73-80
    • Kang, S.S.1    Pak, S.C.2    Choi, S.H.3
  • 29
    • 0037205060 scopus 로고    scopus 로고
    • The water-soluble fraction of bee venom produces antinociceptive and anti-inflammatory effects on rheumatoid arthritis in rats
    • Kwon Y.B., Lee H.J., Han H.J., Mar W.C., Kang S.K., Yoon O.B., Beitz A.J., Lee J.H. The water-soluble fraction of bee venom produces antinociceptive and anti-inflammatory effects on rheumatoid arthritis in rats. Life Sci. 2002, 71:191-204.
    • (2002) Life Sci. , vol.71 , pp. 191-204
    • Kwon, Y.B.1    Lee, H.J.2    Han, H.J.3    Mar, W.C.4    Kang, S.K.5    Yoon, O.B.6    Beitz, A.J.7    Lee, J.H.8
  • 30
    • 0018428905 scopus 로고
    • Activation of microsomal guanylate cyclase by a cytotoxic polypeptide: melittin
    • Lad P.J., Shier W.T. Activation of microsomal guanylate cyclase by a cytotoxic polypeptide: melittin. Biochem. Biophys. Res. Commun. 1979, 89:315-321.
    • (1979) Biochem. Biophys. Res. Commun. , vol.89 , pp. 315-321
    • Lad, P.J.1    Shier, W.T.2
  • 31
    • 0019326961 scopus 로고
    • Interaction of melittin with dimyristoyl phosphatidylcholine liposomes: evidence for boundary lipid by Raman spectroscopy
    • Lavialle F., Levin I.W., Mollay C. Interaction of melittin with dimyristoyl phosphatidylcholine liposomes: evidence for boundary lipid by Raman spectroscopy. Biochim. Biophys. Acta 1980, 600:62-71.
    • (1980) Biochim. Biophys. Acta , vol.600 , pp. 62-71
    • Lavialle, F.1    Levin, I.W.2    Mollay, C.3
  • 33
    • 4444252436 scopus 로고    scopus 로고
    • Use of the tail moment of the lymphocytes to evaluate DNA damage in human biomonitoring studies
    • Lee E., Oh E., Lee J., Sul D., Lee J. Use of the tail moment of the lymphocytes to evaluate DNA damage in human biomonitoring studies. Toxicol. Sci. 2004, 81:121-132.
    • (2004) Toxicol. Sci. , vol.81 , pp. 121-132
    • Lee, E.1    Oh, E.2    Lee, J.3    Sul, D.4    Lee, J.5
  • 34
    • 34548321105 scopus 로고    scopus 로고
    • Cytotoxicity of honeybee (Apis mellifera) venom in normal human lymphocytes and HL-60 cells
    • Lee Y.J., Kang S.J., Kim B.M., Kim Y.J., Woo H.D., Chung H.W. Cytotoxicity of honeybee (Apis mellifera) venom in normal human lymphocytes and HL-60 cells. Chem. Biol. Interact. 2007, 169:189-197.
    • (2007) Chem. Biol. Interact. , vol.169 , pp. 189-197
    • Lee, Y.J.1    Kang, S.J.2    Kim, B.M.3    Kim, Y.J.4    Woo, H.D.5    Chung, H.W.6
  • 35
    • 0242331757 scopus 로고    scopus 로고
    • Therapeutic potential of venom peptides
    • Lewis R.J., Garcia M.L. Therapeutic potential of venom peptides. Nat. Rev. Drug Discov. 2003, 2:790-802.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 790-802
    • Lewis, R.J.1    Garcia, M.L.2
  • 36
    • 0035994880 scopus 로고    scopus 로고
    • Effect of honey bee venom on proliferation of K1735M2 mouse melanoma cells in-vitro and growth of murine B16 melanomas in-vivo
    • Liu X., Chen D., Xie L., Zhang R. Effect of honey bee venom on proliferation of K1735M2 mouse melanoma cells in-vitro and growth of murine B16 melanomas in-vivo. J. Pharm. Pharmacol. 2002, 54:1083-1089.
    • (2002) J. Pharm. Pharmacol. , vol.54 , pp. 1083-1089
    • Liu, X.1    Chen, D.2    Xie, L.3    Zhang, R.4
  • 37
    • 0043234938 scopus 로고    scopus 로고
    • Evaluation of genotoxic risk and oxidative DNA damage in mammalian cells exposed to mycotoxins, patulin and citrinin
    • Liu B.H., Yu F.Y., Wu T.S., Li S.Y., Su M.C., Wang M.C., Shih S.M. Evaluation of genotoxic risk and oxidative DNA damage in mammalian cells exposed to mycotoxins, patulin and citrinin. Toxicol. Appl. Pharmacol. 2003, 191:255-263.
    • (2003) Toxicol. Appl. Pharmacol. , vol.191 , pp. 255-263
    • Liu, B.H.1    Yu, F.Y.2    Wu, T.S.3    Li, S.Y.4    Su, M.C.5    Wang, M.C.6    Shih, S.M.7
  • 38
    • 33645119895 scopus 로고    scopus 로고
    • Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro
    • Maher S., McClean S. Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro. Biochem. Pharmacol. 2006, 71:1289-1298.
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 1289-1298
    • Maher, S.1    McClean, S.2
  • 39
    • 38949175466 scopus 로고    scopus 로고
    • Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol
    • Maher S., McClean S. Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol. Biochem. Pharmacol. 2008, 75:1104-1114.
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 1104-1114
    • Maher, S.1    McClean, S.2
  • 40
    • 33749679450 scopus 로고    scopus 로고
    • Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt
    • Moon D.O., Park S.Y., Heo M.S., Kim K.C., Park C., Ko W.S. Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt. Int. Immunopharmacol. 2006, 6:1796-1807.
    • (2006) Int. Immunopharmacol. , vol.6 , pp. 1796-1807
    • Moon, D.O.1    Park, S.Y.2    Heo, M.S.3    Kim, K.C.4    Park, C.5    Ko, W.S.6
  • 42
    • 0038751806 scopus 로고    scopus 로고
    • Inhibition of mammary carcinoma cell proliferation in vitro and tumor growth in vivo by bee venom
    • Oršolić N., Šver L., Verstovšek S., Terzić S., Basić I. Inhibition of mammary carcinoma cell proliferation in vitro and tumor growth in vivo by bee venom. Toxicon 2003, 41:861-870.
    • (2003) Toxicon , vol.41 , pp. 861-870
    • Oršolić, N.1    Šver, L.2    Verstovšek, S.3    Terzić, S.4    Basić, I.5
  • 43
    • 73549084526 scopus 로고    scopus 로고
    • Potentiation of bleomycin lethality in HeLa and V79 Cells by bee venom
    • Oršolić N. Potentiation of bleomycin lethality in HeLa and V79 Cells by bee venom. Arh. Hig. Rada Toksikol. 2009, 60:317-326.
    • (2009) Arh. Hig. Rada Toksikol. , vol.60 , pp. 317-326
    • Oršolić, N.1
  • 46
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh N.P., McCoy M.T., Tice R.R., Schneider L.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1988, 175:184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, L.L.4
  • 47
    • 0034630349 scopus 로고    scopus 로고
    • A simple method for accurate estimation of apoptotic cells
    • Singh N.P. A simple method for accurate estimation of apoptotic cells. Exp. Cell Res. 2000, 256:328-337.
    • (2000) Exp. Cell Res. , vol.256 , pp. 328-337
    • Singh, N.P.1
  • 48
    • 20544432769 scopus 로고    scopus 로고
    • Apoptosis assessment by the DNA diffusion assay
    • Singh N.P. Apoptosis assessment by the DNA diffusion assay. Methods Mol. Med. 2005, 111:55-67.
    • (2005) Methods Mol. Med. , vol.111 , pp. 55-67
    • Singh, N.P.1
  • 49
    • 33645854059 scopus 로고    scopus 로고
    • Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression
    • Son D.J., Ha S.J., Song H.S., Lim Y., Yun Y.P., Lee J.W., Moon D.C., Park Y.H., Park B.S., Song M.J., Hong J.T. Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression. J. Pharmacol. Exp. Ther. 2006, 317:627-634.
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , pp. 627-634
    • Son, D.J.1    Ha, S.J.2    Song, H.S.3    Lim, Y.4    Yun, Y.P.5    Lee, J.W.6    Moon, D.C.7    Park, Y.H.8    Park, B.S.9    Song, M.J.10    Hong, J.T.11
  • 50
    • 34447312502 scopus 로고    scopus 로고
    • Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds
    • Son D.J., Lee J.W., Lee Y.H., Song H.S., Lee C.K., Hong J.T. Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds. Pharmacol. Ther. 2007, 115:246-270.
    • (2007) Pharmacol. Ther. , vol.115 , pp. 246-270
    • Son, D.J.1    Lee, J.W.2    Lee, Y.H.3    Song, H.S.4    Lee, C.K.5    Hong, J.T.6
  • 51
    • 34250861997 scopus 로고    scopus 로고
    • Apis mellifera venom and melittin block neither NF-kappa B-p50-DNA interactions nor the activation of NF-kappa B, instead they activate the transcription of proinflammatory genes and the release of reactive oxygen intermediates
    • Stuhlmeier K.M. Apis mellifera venom and melittin block neither NF-kappa B-p50-DNA interactions nor the activation of NF-kappa B, instead they activate the transcription of proinflammatory genes and the release of reactive oxygen intermediates. J. Immunol. 2007, 179:655-664.
    • (2007) J. Immunol. , vol.179 , pp. 655-664
    • Stuhlmeier, K.M.1
  • 52
    • 0037340936 scopus 로고    scopus 로고
    • Nucleoplasmic bridges are sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay
    • Thomas P., Umegaki K., Fenech M. Nucleoplasmic bridges are sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay. Mutagenesis 2003, 18:187-194.
    • (2003) Mutagenesis , vol.18 , pp. 187-194
    • Thomas, P.1    Umegaki, K.2    Fenech, M.3
  • 54
    • 49449085608 scopus 로고    scopus 로고
    • Honeybee venom induces calcium-dependent but caspase-independent apoptotic cell death in human melanoma A2058 cells
    • Tu W.C., Wu C.C., Hsieh H.L., Chen C.Y., Hsu S.L. Honeybee venom induces calcium-dependent but caspase-independent apoptotic cell death in human melanoma A2058 cells. Toxicon 2008, 52:318-329.
    • (2008) Toxicon , vol.52 , pp. 318-329
    • Tu, W.C.1    Wu, C.C.2    Hsieh, H.L.3    Chen, C.Y.4    Hsu, S.L.5
  • 55
    • 0034066102 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils
    • Umegaki K., Fenech M. Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis 2000, 15:261-269.
    • (2000) Mutagenesis , vol.15 , pp. 261-269
    • Umegaki, K.1    Fenech, M.2
  • 56
    • 0031964129 scopus 로고    scopus 로고
    • Radioprotection: mechanism and radioprotective agents including honey bee venom
    • Varanda E.A., Tavares D.C. Radioprotection: mechanism and radioprotective agents including honey bee venom. Venom. Anim. Toxins 1998, 4:5-21.
    • (1998) Venom. Anim. Toxins , vol.4 , pp. 5-21
    • Varanda, E.A.1    Tavares, D.C.2
  • 57
    • 0019871670 scopus 로고
    • Incorporation of melittin into phosphatidylcholine bilayers. Study of binding and conformational changes
    • Vogel H. Incorporation of melittin into phosphatidylcholine bilayers. Study of binding and conformational changes. FEBS Lett. 1981, 134:37-42.
    • (1981) FEBS Lett. , vol.134 , pp. 37-42
    • Vogel, H.1
  • 58
    • 0025252436 scopus 로고
    • Hemolytic potency and phospholipase activity of some bee and wasp venoms
    • Watala C., Kowalczyk J.K. Hemolytic potency and phospholipase activity of some bee and wasp venoms. Comp. Biochem. Physiol. C 1990, 97:187-194.
    • (1990) Comp. Biochem. Physiol. C , vol.97 , pp. 187-194
    • Watala, C.1    Kowalczyk, J.K.2
  • 59
    • 0021961153 scopus 로고
    • Oxidative autoactivation of latent collagenase by human neutrophils
    • Weiss S.J., Peppin G., Ortiz X., Ragsdale C., Test S.T. Oxidative autoactivation of latent collagenase by human neutrophils. Science 1985, 227:747-749.
    • (1985) Science , vol.227 , pp. 747-749
    • Weiss, S.J.1    Peppin, G.2    Ortiz, X.3    Ragsdale, C.4    Test, S.T.5


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