Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol

Biochemical Pharmacology

Volumn 75, Issue 5, 2008, Pages 1104-1114

  Maher, Sam ^a   McClean, Siobhán ^a  

^a DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

Author keywords

Antimicrobial peptide; Cholesterol; Cytotoxicity; Intestinal epithelial cells; Melittin; Necrosis; Paracellular permeability enhancer

Indexed keywords

BROXURIDINE; CASPASE; CHOLESTEROL; MELITTIN; METHYL BETA CYCLODEXTRIN; PHOSPHATIDYLSERINE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL DEATH; CELL PROLIFERATION; CELL STRAIN CACO 2; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTESTINE CELL; LC 50; NECROSIS; PRIORITY JOURNAL;

CACO-2 CELLS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CHOLESTEROL; DNA; DNA FRAGMENTATION; EPITHELIAL CELLS; GASTROINTESTINAL TRACT; HUMANS; MELITTEN; NECROSIS; PHOSPHATIDYLSERINES;

EID: 38949175466     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.10.029     Document Type: Article

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