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Volumn 72, Issue 14-15, 2011, Pages 1814-1820

In vitro photochemical and phototoxicological characterization of major constituents in St. John's Wort (Hypericum perforatum) extracts

Author keywords

Guttiferae; In vitro phototoxicity; Reactive oxygen species; Singlet oxygen; St. John's Wort; Superoxide

Indexed keywords

ANTIDEPRESSANT AGENT; BIOLOGICAL PRODUCT; DRUG DERIVATIVE; ENZYME INHIBITOR; HYPERFORIN; HYPERICIN; PERYLENE; PHLOROGLUCINOL; PLANT EXTRACT; PSEUDOHYPERICIN; REACTIVE OXYGEN METABOLITE; TERPENE;

EID: 80051552236     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2011.06.011     Document Type: Article
Times cited : (33)

References (26)
  • 1
    • 0027603947 scopus 로고
    • UV irradiation of nucleic acids: Characterization of photoproducts of thymidylyl-(3′→5′)-2′-deoxy-5-fluorouridine
    • J.L. Alderfer, S.D. Soni, A.V. Arakali, and J.C. Wallace UV irradiation of nucleic acids: characterization of photoproducts of thymidylyl- (3′→5′)-2′-deoxy-5-fluorouridine Photochem. Photobiol. 57 1993 770 776
    • (1993) Photochem. Photobiol. , vol.57 , pp. 770-776
    • Alderfer, J.L.1    Soni, S.D.2    Arakali, A.V.3    Wallace, J.C.4
  • 2
    • 0026251573 scopus 로고
    • Definition of type i and type II photosensitized oxidation
    • C.S. Foote Definition of type I and type II photosensitized oxidation Photochem. Photobiol. 54 1991 659
    • (1991) Photochem. Photobiol. , vol.54 , pp. 659
    • Foote, C.S.1
  • 5
    • 68949110071 scopus 로고    scopus 로고
    • St. John's wort - An overview
    • K. Linde St. John's wort - an overview Forsch. Komplementmed. 16 2009 146 155
    • (2009) Forsch. Komplementmed. , vol.16 , pp. 146-155
    • Linde, K.1
  • 6
    • 0036279441 scopus 로고    scopus 로고
    • Drug-induced cutaneous photosensitivity: Incidence, mechanism, prevention and management
    • D.E. Moore Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management Drug Saf. 25 2002 345 372 (Pubitemid 34634272)
    • (2002) Drug Safety , vol.25 , Issue.5 , pp. 345-372
    • Moore, D.E.1
  • 7
    • 77952983897 scopus 로고    scopus 로고
    • Lessons learned from herbal medicinal products: The example of St. John's Wort (perpendicular)
    • A. Nahrstedt, and V. Butterweck Lessons learned from herbal medicinal products: the example of St. John's Wort (perpendicular) J. Nat. Prod. 73 2010 1015 1021
    • (2010) J. Nat. Prod. , vol.73 , pp. 1015-1021
    • Nahrstedt, A.1    Butterweck, V.2
  • 8
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358 (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 9
    • 41349110622 scopus 로고    scopus 로고
    • Capillary electrophoretic studies on the photogenotoxic potential of pharmaceutical substances
    • DOI 10.1016/j.chroma.2007.09.084, PII S002196730701730X
    • S. Onoue, N. Igarashi, F. Kitagawa, K. Otsuka, and Y. Tsuda Capillary electrophoretic studies on the photogenotoxic potential of pharmaceutical substances J. Chromatogr. A 1188 2008 50 56 (Pubitemid 351452028)
    • (2008) Journal of Chromatography A , vol.1188 , Issue.1 , pp. 50-56
    • Onoue, S.1    Igarashi, N.2    Kitagawa, F.3    Otsuka, K.4    Tsuda, Y.5
  • 10
    • 36849044183 scopus 로고    scopus 로고
    • High-throughput reactive oxygen species (ROS) assay: An enabling technology for screening the phototoxic potential of pharmaceutical substances
    • DOI 10.1016/j.jpba.2007.09.003, PII S073170850700516X
    • S. Onoue, N. Igarashi, S. Yamada, and Y. Tsuda High-throughput reactive oxygen species (ROS) assay: an enabling technology for screening the phototoxic potential of pharmaceutical substances J. Pharm. Biomed. Anal. 46 2008 187 193 (Pubitemid 350225644)
    • (2008) Journal of Pharmaceutical and Biomedical Analysis , vol.46 , Issue.1 , pp. 187-193
    • Onoue, S.1    Igarashi, N.2    Yamada, S.3    Tsuda, Y.4
  • 12
    • 77955473719 scopus 로고    scopus 로고
    • High-throughput screening system for identifying phototoxic potential of drug candidates based on derivatives of reactive oxygen metabolites
    • S. Onoue, M. Ochi, G. Gandy, Y. Seto, N. Igarashi, Y. Yamauchi, and S. Yamada High-throughput screening system for identifying phototoxic potential of drug candidates based on derivatives of reactive oxygen metabolites Pharm. Res. 27 2010 1610 1619
    • (2010) Pharm. Res. , vol.27 , pp. 1610-1619
    • Onoue, S.1    Ochi, M.2    Gandy, G.3    Seto, Y.4    Igarashi, N.5    Yamauchi, Y.6    Yamada, S.7
  • 13
    • 67849108402 scopus 로고    scopus 로고
    • Drug-induced phototoxicity; An early in vitro identification of phototoxic potential of new drug entities in drug discovery and development
    • S. Onoue, Y. Seto, G. Gandy, and S. Yamada Drug-induced phototoxicity; an early in vitro identification of phototoxic potential of new drug entities in drug discovery and development Curr. Drug Saf. 4 2009 123 136
    • (2009) Curr. Drug Saf. , vol.4 , pp. 123-136
    • Onoue, S.1    Seto, Y.2    Gandy, G.3    Yamada, S.4
  • 14
    • 70349236974 scopus 로고    scopus 로고
    • Novel methodology for predicting photogenotoxic risk of pharmaceutical substances based on reactive oxygen species (ROS) and DNA-binding assay
    • S. Onoue, Y. Seto, A. Oishi, and S. Yamada Novel methodology for predicting photogenotoxic risk of pharmaceutical substances based on reactive oxygen species (ROS) and DNA-binding assay J. Pharm. Sci. 98 2009 3647 3658
    • (2009) J. Pharm. Sci. , vol.98 , pp. 3647-3658
    • Onoue, S.1    Seto, Y.2    Oishi, A.3    Yamada, S.4
  • 15
    • 32244449279 scopus 로고    scopus 로고
    • Analytical studies on the prediction of photosensitive/phototoxic potential of pharmaceutical substances
    • DOI 10.1007/s11095-005-8497-9
    • S. Onoue, and Y. Tsuda Analytical studies on the prediction of photosensitive/phototoxic potential of pharmaceutical substances Pharm. Res. 23 2006 156 164 (Pubitemid 43214672)
    • (2006) Pharmaceutical Research , vol.23 , Issue.1 , pp. 156-164
    • Onoue, S.1    Tsuda, Y.2
  • 16
    • 43349089094 scopus 로고    scopus 로고
    • Analytical studies on photochemical behavior of phototoxic substances; effect of detergent additives on singlet oxygen generation
    • DOI 10.1007/s11095-007-9383-4
    • S. Onoue, Y. Yamauchi, T. Kojima, N. Igarashi, and Y. Tsuda Analytical studies on photochemical behavior of phototoxic substances; effect of detergent additives on singlet oxygen generation Pharm. Res. 25 2008 861 868 (Pubitemid 351661831)
    • (2008) Pharmaceutical Research , vol.25 , Issue.4 , pp. 861-868
    • Onoue, S.1    Yamauchi, Y.2    Kojima, T.3    Igarashi, N.4    Tsuda, Y.5
  • 18
    • 0035073478 scopus 로고    scopus 로고
    • Incidence and clinical relevance of the interactions and side effects of hypericum preparations
    • V. Schulz Incidence and clinical relevance of the interactions and side effects of Hypericum preparations Phytomedicine 8 2001 152 160 (Pubitemid 32267101)
    • (2001) Phytomedicine , vol.8 , Issue.2 , pp. 152-160
    • Schulz, V.1
  • 19
    • 31044434122 scopus 로고    scopus 로고
    • Safety of St. John's Wort extract compared to synthetic antidepressants
    • DOI 10.1016/j.phymed.2005.07.005, PII S0944711305002187
    • V. Schulz Safety of St. John's Wort extract compared to synthetic antidepressants Phytomedicine 13 2006 199 204 (Pubitemid 43120322)
    • (2006) Phytomedicine , vol.13 , Issue.3 , pp. 199-204
    • Schulz, V.1
  • 20
    • 57149103144 scopus 로고    scopus 로고
    • Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin
    • G. Seelinger, I. Merfort, and C.M. Schempp Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin Planta Med. 74 2008 1667 1677
    • (2008) Planta Med. , vol.74 , pp. 1667-1677
    • Seelinger, G.1    Merfort, I.2    Schempp, C.M.3
  • 21
    • 0027427260 scopus 로고
    • Phototoxicity caused by hypericum
    • C.P. Siegers, S. Biel, and K.P. Wilhelm Phototoxicity caused by hypericum Nervenheilkunde 12 1993 320 322 (Pubitemid 23329156)
    • (1993) Nervenheilkunde , vol.12 , Issue.6 , pp. 320-322
    • Siegers, C.-P.1    Biel, S.2    Wilhelm, K.-P.3
  • 23
    • 0033914319 scopus 로고    scopus 로고
    • In vitro studies of the phototoxic potential of the antidepressant drugs amitriptyline and imipramine
    • DOI 10.1016/S0014-827X(99)00116-0, PII S0014827X99001160
    • G. Viola, G. Miolo, D. Vedaldi, and F. Dall'Acqua In vitro studies of the phototoxic potential of the antidepressant drugs amitriptyline and imipramine Il Farmaco. 55 2000 211 218 (Pubitemid 30488844)
    • (2000) Farmaco , vol.55 , Issue.3 , pp. 211-218
    • Viola, G.1    Miolo, G.2    Vedaldi, D.3    Dall'Acqua, F.4
  • 24
    • 0034891383 scopus 로고    scopus 로고
    • Role of flavonoids in controlling the phototoxicity of Hypericum perforatum extracts
    • K.P. Wilhelm, S. Biel, and C.P. Siegers Role of flavonoids in controlling the phototoxicity of Hypericum perforatum extracts Phytomedicine 8 2001 306 309 (Pubitemid 32758348)
    • (2001) Phytomedicine , vol.8 , Issue.4 , pp. 306-309
    • Wilhelm, K.-P.1    Wilhelm, K.-P.2    Biel, S.3    Siegers, C.-P.4
  • 25
    • 0030198729 scopus 로고    scopus 로고
    • Hypericin-induced phototoxicity in cultured fibroblasts and swine erythrocytes
    • H. Yu, S.T. Wolford, R. Kegode, W. Zhao, and G.D. Osweller Hypericin-induced phototoxicity in cultured fibroblasts and swine erythrocytes Photochem. Photobiol. 64 1996 168 173
    • (1996) Photochem. Photobiol. , vol.64 , pp. 168-173
    • Yu, H.1    Wolford, S.T.2    Kegode, R.3    Zhao, W.4    Osweller, G.D.5
  • 26
    • 3843130941 scopus 로고    scopus 로고
    • Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro
    • Y. Zou, Y. Lu, and D. Wei Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro J. Agric. Food Chem. 52 2004 5032 5039
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 5032-5039
    • Zou, Y.1    Lu, Y.2    Wei, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.