Capillary electrophoretic studies on the photogenotoxic potential of pharmaceutical substances

Journal of Chromatography A

Volumn 1188, Issue 1, 2008, Pages 50-56

  Onoue, Satomi ^a,c   Igarashi, Naoko ^a   Kitagawa, Fumihiko ^b   Otsuka, Koji ^b   Tsuda, Yoshiko ^a  

^a PFIZER INC   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Capillary electrophoresis; Electron microscopy; Photogenotoxicity; Plasmid DNA; Reactive oxygen species

Indexed keywords

CAPILLARY ELECTROPHORESIS; DNA; GELS; IRRADIATION; PHOTOSENSITIZERS; PLASMA (HUMAN); SKIN; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET RADIATION;

CAPILLARY GEL ELECTROPHORESIS (CGE); PHOTOALLERGY; PHOTOGENOTOXICITY; PHOTOIRRITATION; PLASMID DNA;

DRUG PRODUCTS;

DEUTERIUM; DNA; DRUG; PHOTOSENSITIZING AGENT; PLASMID DNA; QUININE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SINGLET OXYGEN; SODIUM AZIDE;

AGAR GEL ELECTROPHORESIS; ANALYTIC METHOD; ARTICLE; CAPILLARY ELECTROPHORESIS; DNA DAMAGE; GEL ELECTROPHORESIS; GENOTOXICITY; IRRADIATION; OXIDATIVE STRESS; PHOTOTOXICITY; PRIORITY JOURNAL; RADIATION EXPOSURE; SOLAR RADIATION; STRUCTURE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROPHOTOMETRY;

DATA INTERPRETATION, STATISTICAL; DERMATITIS, PHOTOTOXIC; DNA DAMAGE; ELECTROPHORESIS, AGAR GEL; ELECTROPHORESIS, CAPILLARY; LIGHT; MICROSCOPY, ELECTRON, TRANSMISSION; MUTAGENS; OXIDANTS; OXIDATIVE STRESS; PHARMACEUTICAL PREPARATIONS; PLASMIDS; QUININE; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 41349110622     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.09.084     Document Type: Article

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