Novel methodology for predicting photogenotoxic risk of pharmaceutical substances based on reactive oxygen species (ROS) and DNA-binding assay

Journal of Pharmaceutical Sciences

Volumn 98, Issue 10, 2009, Pages 3647-3658

  Onoue, Satomi ^a   Seto, Yoshiki ^a   Oishi, Ami ^a   Yamada, Shizuo ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Capillary electrophoresis; Circular dichroism; DNA binding; Photogenotoxicity; Reactive oxygen species

Indexed keywords

1 DODECYLIMIDAZOLE; ACETYLSALICYLIC ACID; ALTERNARIOL; BENZOCAINE; BERBERINE; CHLORPROMAZINE; DICLOFENAC; DOXYCYCLINE; ERYTHROMYCIN; ETHIDIUM BROMIDE; FUROSEMIDE; IMIDAZOLE; IMIPRAMINE; INDOMETACIN; KETOPROFEN; METHOXSALEN; NALIDIXIC ACID; NAPROXEN; NITROFURANTOIN; NORFLOXACIN; PHENYTOIN; PIROXICAM; PLASMID DNA; PROMETHAZINE; PSORALEN; QUININE; REACTIVE OXYGEN METABOLITE; SULISOBENZONE;

ARTICLE; DNA BINDING; DNA DAMAGE; FLUORESCENCE; GEL ELECTROPHORESIS; GENOTOXICITY; PHOTOSENSITIZATION; PHOTOTOXICITY; RISK FACTOR; SPECTROPHOTOMETRY;

EID: 70349236974     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21670     Document Type: Article

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