Structural basis of the anti-HIV activity of the cyanobacterial Oscillatoria Agardhii agglutinin

Structure

Volumn 19, Issue 8, 2011, Pages 1170-1181

  Koharudin, Leonardus M I ^a   Gronenborn, Angela M ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLUTININ; ALPHA3,ALPHA6 MANNOPENTAOSE; LECTIN; MANNOSE; OSCILLATORY AGARDHII AGGLUTININ; PENTOSE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; CHEMICAL BINDING; CHEMICAL BOND; CRYSTAL STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS; MOLECULAR RECOGNITION; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; OSCILLATORIA; OSCILLATORIA AGARDHII; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

AGGLUTININS; ANTI-HIV AGENTS; APOPROTEINS; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HIV ENVELOPE PROTEIN GP120; MAGNETIC RESONANCE SPECTROSCOPY; MANNOSE-BINDING LECTIN; OLIGOSACCHARIDES; OSCILLATORIA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

CYANOBACTERIA; PLANKTOTHRIX AGARDHII;

EID: 80051503004     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2011.05.010     Document Type: Article

References (37)

1. L.G. Barrientos, E. Matei, F. Lasala, R. Delgado, and A.M. Gronenborn Dissecting carbohydrate-Cyanovirin-N binding by structure-guided mutagenesis: functional implications for viral entry inhibition Protein Eng. Des. Sel. 19 2006 525 535 (Pubitemid 44950458)
2. A. Bax, and S. Grzesiek Methodological advances in protein NMR Acc. Chem. Res. 26 1993 131 138
3. C.A. Bewley Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: structural basis for high-affinity carbohydrate-mediated binding to gp120 Structure 9 2001 931 940 (Pubitemid 32972159)
4. H.R. Bokesch, B.R. O'Keefe, T.C. McKee, L.K. Pannell, G.M. Patterson, R.S. Gardella, R.C. Sowder 2nd, J. Turpin, K. Watson, R.W. Buckheit Jr. , and M.R. Boyd A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium Biochemistry 42 2003 2578 2584 (Pubitemid 36330611)
5. I. Botos, B.R. O'Keefe, S.R. Shenoy, L.K. Cartner, D.M. Ratner, P.H. Seeberger, M.R. Boyd, and A. Wlodawer Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides J. Biol. Chem. 277 2002 34336 34342
6. M.R. Boyd, K.R. Gustafson, J.B. McMahon, R.H. Shoemaker, B.R. O'Keefe, T. Mori, R.J. Gulakowski, L. Wu, M.I. Rivera, and C.M. Laurencot Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development Antimicrob. Agents Chemother. 41 1997 1521 1530 (Pubitemid 27289680)
7. CCP4 (Collaborative Computational Project, Number 4) The CCP4 suite: programs for protein crystallography Acta Crystallogr. D Biol. Crystallogr. 50 1994 760 763
8. H. Chiba, J. Inokoshi, H. Nakashima, S. Omura, and H. Tanaka Actinohivin, a novel anti-human immunodeficiency virus protein from an actinomycete, inhibits viral entry to cells by binding high-mannose type sugar chains of gp120 Biochem. Biophys. Res. Commun. 316 2004 203 210 (Pubitemid 38299146)
9. I.W. Davis, A. Leaver-Fay, V.B. Chen, J.N. Block, G.J. Kapral, X. Wang, L.W. Murray, W.B. Arendall 3rd, J. Snoeyink, J.S. Richardson, and D.C. Richardson MolProbity: all-atom contacts and structure validation for proteins and nucleic acids Nucleic Acids Res. 35 Web Server issue 2007 W375-W83
10. F. Delaglio, S. Grzesiek, G.W. Vuister, G. Zhu, J. Pfeifer, and A. Bax NMRPipe: a multidimensional spectral processing system based on UNIX pipes J. Biomol. NMR 6 1995 277 293
11. DeLano, W.L. (2002). The PyMOL Molecular Graphics System. http://www.pymol.org.
12. K.J. Doores, C. Bonomelli, D.J. Harvey, S. Vasiljevic, R.A. Dwek, D.R. Burton, M. Crispin, and C.N. Scanlan Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens Proc. Natl. Acad. Sci. USA 107 2010 13800 13805
13. D.M. Eckert, and P.S. Kim Mechanisms of viral membrane fusion and its inhibition Annu. Rev. Biochem. 70 2001 777 810 (Pubitemid 32662225)
14. P. Emsley, and K. Cowtan Coot: model-building tools for molecular graphics Acta Crystallogr. D Biol. Crystallogr. 60 2004 2126 2132 (Pubitemid 41742764)
15. H. Feinberg, D.A. Mitchell, K. Drickamer, and W.I. Weis Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR Science 294 2001 2163 2166 (Pubitemid 33150672)
16. E.O. Freed, and M.A. Martin The role of human immunodeficiency virus type 1 envelope glycoproteins in virus infection J. Biol. Chem. 270 1995 23883 23886
17. G.G. Hammes, Y.C. Chang, and T.G. Oas Conformational selection or induced fit: a flux description of reaction mechanism Proc. Natl. Acad. Sci. USA 106 2009 13737 13741
18. X. Ji, Y. Chen, J. Faro, H. Gewurz, J. Bremer, and G.T. Spear Interaction of human immunodeficiency virus (HIV) glycans with lectins of the human immune system Curr. Protein Pept. Sci. 7 2006 317 324
19. B.A. Johnson, and R.A. Blevins NMRView: a computer program for the visualization and analysis of NMR data J. Biomol. NMR 4 1994 603 614
20. L.M. Koharudin, W. Furey, and A.M. Gronenborn Novel fold and carbohydrate specificity of the potent anti-HIV cyanobacterial lectin from Oscillatoria Agardhii J. Biol. Chem. 286 2011 1588 1597
21. P.D. Kwong, R. Wyatt, J. Robinson, R.W. Sweet, J. Sodroski, and W.A. Hendrickson Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody Nature 393 1998 648 659 (Pubitemid 28289647)
22. A.J. McCoy Solving structures of protein complexes by molecular replacement with Phaser Acta Crystallogr. D Biol. Crystallogr. 63 2007 32 41
23. R.L. McFeeters, C. Xiong, B.R. O'Keefe, H.R. Bokesch, J.B. McMahon, D.M. Ratner, R. Castelli, P.H. Seeberger, and R.A. Byrd The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors J. Mol. Biol. 369 2007 451 461 (Pubitemid 46678045)
24. T. Mori, B.R. O'Keefe, R.C. Sowder 2nd, S. Bringans, R. Gardella, S. Berg, P. Cochran, J.A. Turpin, R.W. Buckheit Jr. , J.B. McMahon, and M.R. Boyd Isolation and characterization of Griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp J. Biol. Chem. 280 2005 9345 9353 (Pubitemid 40409628)
25. T. Moulaei, S.R. Shenoy, B. Giomarelli, C. Thomas, J.B. McMahon, Z. Dauter, B.R. O'Keefe, and A. Wlodawer Monomerization of viral entry inhibitor Griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity Structure 18 2010 1104 1115
26. G.N. Murshudov, A.A. Vagin, and E.J. Dodson Refinement of macromolecular structures by the maximum-likelihood method Acta Crystallogr. D Biol. Crystallogr. 53 1997 240 255 (Pubitemid 27235885)
27. E.F. Pettersen, T.D. Goddard, C.C. Huang, G.S. Couch, D.M. Greenblatt, E.C. Meng, and T.E. Ferrin UCSF Chimera - a visualization system for exploratory research and analysis J. Comput. Chem. 25 2004 1605 1612
28. J.W. Pflugrath The finer things in X-ray diffraction data collection Acta Crystallogr. D Biol. Crystallogr. 55 1999 1718 1725 (Pubitemid 29504426)
29. S. Pöhlmann, F. Baribaud, B. Lee, G.J. Leslie, M.D. Sanchez, K. Hiebenthal-Millow, J. Münch, F. Kirchhoff, and R.W. Doms DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus J. Virol. 75 2001 4664 4672 (Pubitemid 32381508)
30. T. Sato, and K. Hori Cloning, expression, and characterization of a novel anti-HIV lectin from the cultured cyanobacterium, Oscillatoria agardhii Fish. Sci. 75 2009 743 753
31. Y. Sato, S. Okuyama, and K. Hori Primary structure and carbohydrate binding specificity of a potent anti-HIV lectin isolated from the filamentous cyanobacterium Oscillatoria agardhii J. Biol. Chem. 282 2007 11021 11029 (Pubitemid 47100773)
32. T. Satoh, Y. Chen, D. Hu, S. Hanashima, K. Yamamoto, and Y. Yamaguchi Structural basis for oligosaccharide recognition of misfolded glycoproteins by OS-9 in ER-associated degradation Mol. Cell 40 2010 905 916
33. H. Tanaka, H. Chiba, J. Inokoshi, A. Kuno, T. Sugai, A. Takahashi, Y. Ito, M. Tsunoda, K. Suzuki, and A. Takénaka Mechanism by which the lectin actinohivin blocks HIV infection of target cells Proc. Natl. Acad. Sci. USA 106 2009 15633 15638
34. D.C. Williams Jr. , J.Y. Lee, M. Cai, C.A. Bewley, and G.M. Clore Crystal structures of the HIV-1 inhibitory cyanobacterial protein MVL free and bound to Man3GlcNAc2: structural basis for specificity and high-affinity binding to the core pentasaccharide from n-linked oligomannoside J. Biol. Chem. 280 2005 29269 29276 (Pubitemid 41161381)
35. T. Wlodarski, and B. Zagrovic Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin Proc. Natl. Acad. Sci. USA 106 2009 19346 19351
36. M. Yamaguchi, T. Ogawa, K. Muramoto, Y. Kamio, M. Jimbo, and H. Kamiya Isolation and characterization of a mannan-binding lectin from the freshwater cyanobacterium (blue-green algae) Microcystis viridis Biochem. Biophys. Res. Commun. 265 1999 703 708
37. N.E. Ziółkowska, B.R. O'Keefe, T. Mori, C. Zhu, B. Giomarelli, F. Vojdani, K.E. Palmer, J.B. McMahon, and A. Wlodawer Domain-swapped structure of the potent antiviral protein Griffithsin and its mode of carbohydrate binding Structure 14 2006 1127 1135 (Pubitemid 44056021)