Small heat shock protein as a multifunctional scaffold: Integrated tumor targeting and caspase imaging within a single cage

Biomacromolecules

Volumn 12, Issue 8, 2011, Pages 3099-3106

  Choi, Seung Hye ^a,b   Kwon, Ick Chan ^a   Hwang, Kwang Yeon ^b   Kim, In San ^c   Ahn, Hyung Jun ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICANCER DRUG; BIOMEDICAL MATERIAL; CANCER CELLS; CASPASES; ENHANCED PERMEABILITY AND RETENTION EFFECTS; GENETICALLY MODIFIED; IMAGING AGENT; IN-VIVO; LIVE CELL; MULTIFUNCTIONAL SCAFFOLD; PROTEIN CAGES; SMALL HEAT SHOCK PROTEINS; TAIL VEINS; TUMOR TARGETING; TUMOR TISSUES;

BIOMEDICAL ENGINEERING; CELLS; CHEMICAL MODIFICATION; DISEASES; DRUG THERAPY; MAMMALS; PROTEINS; TUMORS;

SCAFFOLDS (BIOLOGY);

CASPASE; CISPLATIN; HEAT SHOCK PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER TISSUE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DNA MODIFICATION; DRUG EFFICACY; ENDOCYTOSIS; ENZYME ACTIVITY; FLUORESCENCE IMAGING; IMAGING SYSTEM; INTERNALIZATION; LIGAND BINDING; MACROMOLECULE; MALE; MOLECULAR IMAGING; MOUSE; NEAR INFRARED FLUORESCENCE IMAGING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CAGE; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; WHOLE BODY IMAGING;

ANIMALS; CASPASES; ENDOCYTOSIS; ESCHERICHIA COLI; HEAT-SHOCK PROTEINS; HELA CELLS; HUMANS; METHANOCOCCUS; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NEOPLASMS;

MUS;

EID: 80051482370     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm200743g     Document Type: Article

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