Short-term plasticity of gray matter associated with leptin deficiency and replacement

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 8, 2011, Pages

  London, Edythe D ^a,b,c   Berman, Steven M ^a,c   Chakrapani, Shruthi ^a   Delibasi, Tuncay ^d   Monterosso, John ^e   Erol, H Kutlu ^f   Paz Filho, Gilberto ^g   Wong, Ma Li ^g   Licinio, Julio ^g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d American Hospital ^*  (Turkey)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^f AMERICAN HOSPITAL   (Albania)

^g Australian National University   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN RECEPTOR; R METHULEPTIN; RECOMBINANT LEPTIN; UNCLASSIFIED DRUG;

ADULT; ANTERIOR CINGULATE; ARTICLE; BODY MASS; BRAIN; CASE REPORT; CEREBELLUM; CORRELATION ANALYSIS; DRUG DOSE REDUCTION; DRUG RESPONSE; FEMALE; GENE; GENE MUTATION; GRAY MATTER; HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; IN VIVO STUDY; LEPTIN DEFICIENCY; LEPTIN GENE; MALE; NERVE CELL PLASTICITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PULVINAR; THALAMUS; VOXEL BASED MORPHOMETRY;

ADULT; BODY MASS INDEX; CEREBELLUM; FEMALE; GYRUS CINGULI; HUMANS; HYPERPHAGIA; LEPTIN; MAGNETIC RESONANCE IMAGING; MALE; NEUROGENESIS; NEURONAL PLASTICITY; NEURONS; PULVINAR; RECOMBINANT PROTEINS;

EID: 79961238736     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-0314     Document Type: Article

References (40)

1. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F 1995 Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543
2. Ozata M, Ozdemir IC, Licinio J 1999 Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J Clin Endocrinol Metab 84:3686-3695 (Pubitemid 30645226)
3. Farooqi IS, O'Rahilly S 2009 Leptin: a pivotal regulator of human energy homeostasis. Am J Clin Nutr 89:980S-984S
4. Licinio J, Caglayan S, Ozata M, Yildiz BO, de Miranda PB, O'Kirwan F, Whitby R, Liang L, Cohen P, Bhasin S, Krauss RM, Veldhuis JD, Wagner AJ, DePaoli AM, McCann SM, Wong ML 2004 Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proc Natl Acad Sci USA 101:4531-4536 (Pubitemid 38437445)
5. Ahima RS, Bjorbaek C, Osei S, Flier JS 1999 Regulation of neuronal and glial proteins by leptin: implications for brain development. Endocrinology 140:2755-2762 (Pubitemid 32245155)
6. Gustafson D, Lissner L, Bengtsson C, Björkelund C, Skoog I 2004 A 24-year follow-up of body mass index and cerebral atrophy. Neurology 63:1876-1881 (Pubitemid 39532384)
7. Pannacciulli N, Del Parigi A, Chen K, Le DS, Reiman EM, Tataranni PA 2006 Brain abnormalities in human obesity: a voxel-based morphometric study. Neuroimage 31:1419-1425 (Pubitemid 43949229)
8. Taki Y, Kinomura S, Sato K, Inoue K, Goto R, Okada K, Uchida S, Kawashima R, Fukuda H 2008 Relationship between body mass index and gray matter volume in 1,428 healthy individuals. Obesity (Silver Spring) 16:119-124 (Pubitemid 351271960)
9. Gazdzinski S, Kornak J, Weiner MW, Meyerhoff DJ 2008 Body mass index and magnetic resonance markers of brain integrity in adults. Ann Neurol 63:652-657
10. Raji CA, Ho AJ, Parikshak NN, Becker JT, Lopez OL, Kuller LH, Hua X, Leow AD, Toga AW, Thompson PM 2010 Brain structure and obesity. Hum Brain Mapp 31:353-364
11. Baicy K, London ED, Monterosso J, Wong ML, Delibasi T, Sharma A, Licinio J 2007 Leptin replacement alters brain response to food cues in genetically leptin-deficient adults. Proc Natl Acad Sci USA 104:18276-18279 (Pubitemid 350210857)
12. Farooqi IS, Bullmore E, Keogh J, Gillard J, O'Rahilly S, Fletcher PC 2007 Leptin regulates striatal regions and human eating behavior. Science 317:1355 (Pubitemid 47417470)
13. Matochik JA, London ED, Yildiz BO, Ozata M, Caglayan S, DePaoli AM, Wong ML, Licinio J 2005 Effect of leptin replacement on brain structure in genetically leptin-deficient adults. J Clin Endocrinol Metab 90:2851-2854 (Pubitemid 40686335)
14. Morrison CD 2009 Leptin signaling in brain: a link between nutrition and cognition? Biochim Biophys Acta 1792:401-408
15. Paz-Filho G, Wong ML, Licinio J 2010 The procognitive effects of leptin in the brain and their clinical implications. Int J Clin Pract 64:1808-1812
16. Paz-Filho G, Esposito K, Hurwitz B, Sharma A, Dong C, Andreev V, Delibasi T, Erol H, Ayala A, Wong ML, Licinio J 2008 Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients. Am J Physiol Endocrinol Metab 295:E1401-E1408
17. Paz-Filho GJ, Andrews D, Esposito K, Erol HK, Delibasi T, Wong ML, Licinio J 2009 Effects of leptin replacement on risk factors for cardiovascular disease in genetically leptin-deficient subjects. Horm Metab Res 41:164-167
18. Galgani JE, Greenway FL, Caglayan S, Wong ML, Licinio J, Ravussin E 2010 Leptin replacement prevents weight loss-induced metabolic adaptation in congenital leptin-deficient patients. J Clin Endocrinol Metab 95:851-855
19. Ashburner J, Friston KJ 2000 Voxel-based morphometry - the methods. Neuroimage 11:805-821 (Pubitemid 30437668)
20. Good CD, Scahill RI, Fox NC, Ashburner J, Friston KJ, Chan D, Crum WR, Rossor MN, Frackowiak RS 2002 Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias. Neuroimage 17:29-46
21. Moorhead TW, Job DE, Spencer MD, Whalley HC, Johnstone EC, Lawrie SM 2005 Empirical comparison of maximal voxel and nonisotropic adjusted cluster extent results in a voxel-based morphometry study of comorbid learning disability with schizophrenia. Neuroimage 28:544-552 (Pubitemid 41540365)
22. Tataranni PA, Gautier JF, Chen K, Uecker A, Bandy D, Salbe AD, Pratley RE, Lawson M, Reiman EM, Ravussin E 1999 Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography. Proc Natl Acad Sci USA 96:4569-4574 (Pubitemid 29190377)
23. Hu X, Okamura N, Arai H, Higuchi M, Maruyama M, Itoh M, Yamaguchi K, Sasaki H 2002 Neuroanatomical correlates of low body weight in Alzheimer's disease: a PET study. Prog Neuropsychopharmacol Biol Psychiatry 26:1285-1289 (Pubitemid 35341579)
24. Uher R, Brammer MJ, Murphy T, Campbell IC, Ng VW, Williams SC, Treasure J 2003 Recovery and chronicity in anorexia nervosa: brain activity associated with differential outcomes. Biol Psychiatry 54:934-942 (Pubitemid 37311357)
25. Van Vugt DA 2010 Brain imaging studies of appetite in the context of obesity and the menstrual cycle. Hum Reprod Update 16:276-292
26. Clower DM, West RA, Lynch JC, Strick PL 2001 The inferior parietal lobule is the target of output from the superior colliculus, hippocampus, and cerebellum. J Neurosci 21:6283-6291 (Pubitemid 32737759)
27. Mendoza J, Pévet P, Felder-Schmittbuhl MP, Bailly Y, Challet E 2010 The cerebellum harbors a circadian oscillator involved in food anticipation. J Neurosci 30:1894-1904
28. Grant S, London ED, Newlin DB, Villemagne VL, Liu X, Contoreggi C, Phillips RL, Kimes AS, Margolin A 1996 Activation of memory circuits during cue-elicited cocaine craving. Proc Natl Acad Sci USA 93:12040-12045 (Pubitemid 26347245)
29. Malik S, McGlone F, Bedrossian D, Dagher A 2008 Ghrelin modulates brain activity in areas that control appetitive behavior. Cell Metab 7:400-409 (Pubitemid 351598026)
30. Lieb W, Beiser AS, Vasan RS, Tan ZS, Au R, Harris TB, Roubenoff R, Auerbach S, DeCarli C, Wolf PA, Seshadri S 2009 Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA 302:2565-2572
31. Pannacciulli N, Le DS, Chen K, Reiman EM, Krakoff J 2007 Relationships between plasma leptin concentrations and human brain structure: a voxel-based morphometric study. Neurosci Lett 412:248-253 (Pubitemid 46109158)
32. Narita K, Kosaka H, Okazawa H, Murata T, Wada Y 2009 Relationship between plasma leptin level and brain structure in elderly: a voxel-based morphometric study. Biol Psychiatry 65:992-994
33. Rosenbaum M, Sy M, Pavlovich K, Leibel RL, Hirsch J 2008 Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli. J Clin Invest 118:2583-2591 (Pubitemid 351949785)
34. Burguera B, Couce ME, Long J, Lamsam J, Laakso K, Jensen MD, Parisi JE, Lloyd RV 2000 The long form of the leptin receptor (OBRb) is widely expressed in the human brain. Neuroendocrinology 71:187-195 (Pubitemid 30157693)
35. Oldreive CE, Harvey J, Doherty GH 2008 Neurotrophic effects of leptin on cerebellar Purkinje but not granule neurons in vitro. Neurosci Lett 438:17-21
36. Gould E 2007 How widespread is adult neurogenesis in mammals? Nat Rev Neurosci 8:481-488 (Pubitemid 46789229)
37. Garza JC, Guo M, Zhang W, Lu XY 2008 Leptin increases adult hippocampal neurogenesis in vivo and in vitro. J Biol Chem 283:18238-18247
38. Udagawa J, Nimura M, Otani H 2006 Leptin affects oligodendroglial development in the mouse embryonic cerebral cortex. Neuro Endocrinol Lett 27:177-182 (Pubitemid 43970790)
39. Paz-Filho G, Mastronardi C, Delibasi T, Wong ML, Licinio J 2010 Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy. Arq Bras Endocrinol Metabol 54:690-697
40. Draganski B, Gaser C, Busch V, Schuierer G, Bogdahn U, May A 2004 Neuroplasticity: changes in grey matter induced by training. Nature 427:311-312 (Pubitemid 38133650)