Steatotic liver: A suitable source for the isolation of hepatic progenitor cells

Liver International

Volumn 31, Issue 8, 2011, Pages 1231-1238

  Tolosa, Laia ^a   Bonora Centelles, Ana ^a   Teresa Donato, M ^a,b,c   Pareja, Eugenia ^a   Negro, Alejandro ^a   López, Silvia ^a   Castell, José V ^a,b,c   Jose gomez lechon M ^a,b  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Cell transplantation; Hepatic progenitor cells; Steatosis

Indexed keywords

CHOLINE; EPITHELIAL CELL ADHESION MOLECULE; LIPID; METHIONINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL ISOLATION; CELL THERAPY; CONTROLLED STUDY; DIET; DISEASE MARKER; FATTY LIVER; FEMALE; LIPID LIVER LEVEL; LIVER TRANSPLANTATION; MOUSE; NONHUMAN; RODENT; STEM CELL;

ANIMALS; ANTIGENS, DIFFERENTIATION; ANTIGENS, NEOPLASM; ANTIGENS, THY-1; BIOLOGICAL MARKERS; CELL ADHESION MOLECULES; CELL SEPARATION; CHOLINE DEFICIENCY; DISEASE MODELS, ANIMAL; FATTY LIVER; FLOW CYTOMETRY; HUMANS; LIVER; MALE; METHIONINE; RATS; STEM CELLS; TIME FACTORS;

EID: 79961201909     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02609.x     Document Type: Article

References (43)

1. Dhawan A, Mitry RR, Hughes RD. Hepatocyte transplantation for liver-based metabolic disorders. J Inherit Metab Dis 2006; 3: 431-5.
2. Strom SC, Chowdhury JR, Fox IJ. Hepatocyte transplantation for the treatment of human disease. Semin Liver Dis 1999; 19: 39-48.
3. Dhawan A, Puppi J, Hughes RD, Mitry RR. Human hepatocyte transplantation: current experience and future challenges. Nat Rev Gastroenterol Hepatol 2010; 7: 288-98.
4. Smets F, Najimi M, Sokal EM. Cell transplantation in the treatment of liver diseases. Pediatr Transplant 2008; 12: 6-13.
5. Weiss TS, Lichtenauer M, Kirchner S, et al. Hepatic progenitor cells from adult human livers for cell transplantation. Gut 2008; 57: 1129-38.
6. Schmelzer E, Zhang L, Bruce A, et al. Human hepatic stem cells from fetal and postnatal donors. J Exp Med 2007; 204: 1973-87.
7. Forster N, Palmer JA, Yeoh G, et al. Expansion and hepatocytic differentiation of liver progenitor cells in vivo using a vascularized tissue engineering chamber in mice. Tissue Eng Part C Methods 2011; 17: 359-66.
8. Chen Y, Zhou H, Sarver AL, et al. Hepatic differentiation of liver-derived progenitor cells and their characterization by microRNA analysis. Liver Transpl 2010; 16: 1086-97.
9. Fausto N, Campbell JS, Riehle KJ. Liver regeneration. Hepatology 2006; 2: S45-53.
10. Michalopoulos GK, Defrances MC. Liver regeneration. Science 1997; 276: 60-6.
11. Fausto N, Campbell JS. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech Dev 2003; 120: 117-30.
12. Schmelzer E, Wauthier E, Reid LM. The phenotypes of pluripotent human hepatic progenitors. Stem Cells 2006; 24: 1852-8.
13. Roskams TA, Libbrecht L, Desmet VJ. Progenitor cells in diseased human liver. Semin Liver Dis 2003; 23: 385-96.
14. Cantz T, Manns MP, Ott M. Stem cells in liver regeneration and therapy. Cell Tissue Res 2008; 331: 271-82.
15. Terrace JD, Currie IS, Hay DC, et al. Progenitor cell characterization and location in the developing human liver. Stem Cells Dev 2007; 16: 771-8.
16. Yovchev MI, Grozdanov PN, Joseph B, Gupta S, Dabeva MD. Novel hepatic progenitor cell surface markers in the adult rat liver. Hepatology 2007; 45: 139-49.
17. Herrera MB, Bruno S, Buttiglieri S, et al. Isolation and characterization of a stem cell population from adult human liver. Stem Cells 2006; 24: 2840-50.
18. Yovchev MI, Grozdanov PN, Zhou H, Racherla H, Guha C, Dabeva MD. Identification of adult hepatic progenitor cells capable of repopulating injured rat liver. Hepatology 2008; 47: 636-47.
19. Zhang L, Theise N, Chua M, Reid LM. The stem cell niche of human livers: symmetry between development and regeneration. Hepatology 2008; 48: 1598-607.
20. Roskams T, Yang SQ, Koteish A, et al. Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease. Am J Pathol 2003; 163: 1301-11.
21. Oertel M, Menthena A, Chen YQ, Teisner B, Jensen CH, Shafritz DA. Purification of fetal liver stem/progenitor cells containing all the repopulation potential for normal adult rat liver. Gastroenterology 2008; 134: 823-32.
22. Wang X, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Grompe M. The origin and liver repopulating capacity of murine oval cells. Proc Natl Acad Sci USA 2003; 100: 11881-8.
23. Yasui O, Miura N, Terada K, Kawarada Y, Koyama K, Sugiyama T. Isolation of oval cells from Long-Evans Cinnamon rats and their transformation into hepatocytes in vivo in the rat liver. Hepatology 1997; 25: 329-34.
24. Fleig SV, Choi SS, Yang L, et al. Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice. Lab Invest 2007; 87: 1227-39.
25. Yang S, Koteish A, Lin H, et al. Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. Hepatology 2004; 39: 403-11.
26. Evarts RP, Nagy P, Marsden E, Thorgeirsson SS. A precursor-product relationship exists between oval cells and hepatocytes in rat liver. Carcinogenesis 1987; 8: 1737-40.
27. Akhurst B, Croager EJ, Farley-Roche CA, et al. A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver. Hepatology 2001; 34: 519-22.
28. Sagias FG, Mitry RR, Hughes RD, et al. N-acetylcysteine improves the viability of human hepatocytes isolated from severely steatotic donor liver tissue. Cell Transplant 2010; 19: 1487-92.
29. Banner BF, Savas L, Zivny J, Tortorelli K, Bonkovsky HL. Ubiquitin as a marker of cell injury in nonalcoholic steatohepatitis. Am J Clin Pathol 2000; 114: 860-6.
30. Bonora-Centelles A, Donato MT, Lahoz A, et al. Functional characterization of hepatocytes for cell transplantation: customized cell preparation for each receptor. Cell Transplant 2010; 19: 21-8.
31. Gomez-Lechon MJ, Donato MT, Martinez-Romero A, Jimenez N, Castell JV, O'connor JE. A human hepatocellular in vitro model to investigate steatosis. Chem Biol Interact 2007; 165: 106-16.
32. Gomez-Lechon MJ, Lahoz A, Jimenez N, Vicente Castell J, Donato MT. Cryopreservation of rat, dog and human hepatocytes: influence of preculture and cryoprotectants on recovery, cytochrome P450 activities and induction upon thawing. Xenobiotica 2006; 36: 457-72.
33. Donato MT, Ponsoda X, O'connor E, Castell JV, Gomez-Lechon MJ. Role of endogenous nitric oxide in liver-specific functions and survival of cultured rat hepatocytes. Xenobiotica 2001; 31: 249-64.
34. He ZP, Tan WQ, Tang YF, Zhang HJ, Feng MF. Activation, isolation, identification and in vitro proliferation of oval cells from adult rat livers. Cell Prolif 2004; 37: 177-87.
35. Vetelainen R, Van Vliet A, Van Gulik TM. Essential pathogenic and metabolic differences in steatosis induced by choline or methione-choline deficient diets in a rat model. J Gastroenterol Hepatol 2007; 22: 1526-33.
36. Weltman MD, Farrell GC, Liddle C. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology 1996; 111: 1645-53.
37. Marsman WA, Wiesner RH, Rodriguez L, et al. Use of fatty donor liver is associated with diminished early patient and graft survival. Transplantation 1996; 62: 1246-51.
38. Alexandre E, Cahn M, Abadie-Viollon C, et al. Influence of pre-, intra- and post-operative parameters of donor liver on the outcome of isolated human hepatocytes. Cell Tissue Bank 2002; 3: 223-33.
39. Alexandrova K, Griesel C, Barthold M, et al. Large-scale isolation of human hepatocytes for therapeutic application. Cell Transplant 2005; 14: 845-53.
40. Zhang A, London R, Schulz FM, et al. Human liver progenitor cell lines are readily established from non-tumorous tissue adjacent to hepatocellular carcinoma. Stem Cells Dev 2010; 19: 1277-84.
41. Farrell GC, Teoh NC, Mccuskey RS. Hepatic microcirculation in fatty liver disease. Anat Rec (Hoboken) 2008; 291: 684-92.
42. Haridass D, Narain N, Ott M. Hepatocyte transplantation: waiting for stem cells. Curr Opin Organ Transplant 2008; 13: 627-32.
43. Najimi M, Khuu DN, Lysy PA, et al. Adult-derived human liver mesenchymal-like cells as a potential progenitor reservoir of hepatocytes? Cell Transplant 2007; 16: 717-28.