Isolation of oval cells from long-evans cinnamon rats and their transformation into hepatocytes in vivo in the rat liver

Hepatology

Volumn 25, Issue 2, 1997, Pages 329-334

  Yasui, Ouki ^a   Miura, Naoyuki ^a   Terada, Kunihiko ^a   Kawarada, Yoshihiko ^a   Koyama, Kenji ^a   Sugiyama, Toshihiro ^a  

^a AKITA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALPHA FETOPROTEIN; CYTOKERATIN; GAMMA GLUTAMYLTRANSFERASE;

ANIMAL MODEL; ARTICLE; CELL TRANSFORMATION; CELL TRANSPLANTATION; CELL TYPE; LIVER CELL; LIVER REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

EID: 0031025566     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250213     Document Type: Article

References (25)

1. Fausto N. Hepatocyte differentiation and progenitor cells. Curr Opin Cell Biol 1990;2:1036-1042.
2. Dempo K, Chisaka N, Yoshida Y, Kaneko A, Onoe T. Immunofluorescent study on α-fetoprotein-producing cells in the early stage of 3′-methyl-4-dimethylaminoazobenzene carcinogenesis. Cancer Res 1975;35:1282-1287.
3. Farber E. Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamionofluorene, and 3′-methyl-4-dimetylaminoazobenzene. Cancer Res 1956;16:142-155.
4. Grisham JW, Hartroft WS. Morphologic identification by electron microscopy of "oval cells" in experimental hepatic degeneration. Lab Invest 1961; 10:317-332.
5. Lenzi R, Liu MH, Tarsetti F, Slott PA, Alpini G, Zhai WR, Paronetto F, et al. Histogenesis of bile duct-like cells proliferating during ethionine hepatocarcinogenesis. Lab Invest 1992;66:390-402.
6. Sell S, Salman S. Light- and electron-microscopic autoradiographic analysis of proliferating cells during the early stages of chemical hepatocarcinogenesis in the rat induced by feeding N-2-fluorenylacetamide in a choline-deficient diet. Am J Pathol 1984;114:287-300.
7. Evarts RP, Nagy P, Marsden E, Thorgeirsson SS. In situ hybridization studies on expression of albumin and α-fetoprotein during the early stage of neoplastic transformation in rat liver. Cancer Res 1987;47:5469-5475.
8. Evarts RP, Nagy P, Marsden E, Thorgeirsson SS. A precursor-product relationship exists between oval cells and hepatocytes in rat liver. Carcinogenesis 1987;8:1737-1740.
9. Evarts RP, Nagy P, Nakatsukasa H, Marsden E, Thorgeirsson SS. In vivo differentiation of rat liver oval cells into hepatocytes. Cancer Res 1989; 49:1541-1547.
10. Pack R, Heck R, Dienes HP, Oesch F, Steinberg P. Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells from carcinogen-fed rats. Exp Cell Res 1993;204:198-209.
11. Braun L, Goyette M, Yaswen P, Thompson NL, Fausto N. Growth in culture and tumorigenicity after transfection with the ras oncogene of liver epithelial cells from carcinogen-treated rats. Cancer Res 1987;47:4116-4124.
12. Tsao M, Smith JD, Nelson KD, Grisham JW. A diploid epithelial cell line from normal adult rat liver with phenotypic properties of 'oval' cells. Exp Cell Res 1984;154:38-52.
13. Yoshida MC, Sasaki M, Masuda R. Origin of the LEC strain with a new mutation causing hereditary hepatitis. In: Mori M, Yoshida MC, Takeichi N, Taniguchi N, eds. The LEC rat, a new model for hepatitis and liver cancer. Tokyo: Springer-Verlag, 1991:3-10.
14. Wu J, Forbes JR, Chen HS, Cox DW. The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Nat Genet 1994;7:541-545.
15. Nagase S, Shimamune K. Albumin-deficient rat mutant. Science 1979; 205:590-591.
16. Vargas EJ, Shoho AR, Linder MC. Copper transport in the Nagase analbuminemic rat. Am J Physiol 1994;267:259-269.
17. Yaswen P, Hayner NT, Fausto N. Isolation of oval cells by centrifugal elutriation and comparison with other cell types purified from normal and preneoplastic livers. Cancer Res 1984;44:324-331.
18. Rutenburg AM, Kim H, Fischbein JW, Hanker JS, Wasserkrug HL, Seligman AM. Histochemical and ultrastructural demonstration of γ-glutamyl transpeptidase activity. J Histochem Cytochem 1969;17:517-526.
19. Pillai S, Zull JE. Production of biologically active fragments of parathyroid hormone by isolated Kupffer cells. J Biol Chem 1986;261:14919-14923.
20. Terada K, Kawarada Y, Miura N, Yasui O, Koyama K, Sugiyama T. Copper incorporation into ceruloplasmin in rat livers. Biochim Biophys Acta 1995; 1270:58-62.
21. Friedrich G, Soriano P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 1991;5:1513-1523.
22. Ishibashi M, Moriyoshi K, Sasaki Y, Shiota K, Nakanishi S, Kageyama R. Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J 1994; 13:1799-1805.
23. Parola M, Cheeseman KH, Biocca ME, Dianzani MU, Slater TF. Biochemical studies on bile duct epithelial cells isolated from rat liver. J Hepatol 1990;10:341-345.
24. Coleman WB, Wennerberg AE, Smith GJ, Grisham JW. Regulation of the differentiation of diploid and some aneuploid rat liver epithelial (stemlike) cells by the hepatic microenvironment. Am J Pathol 1993;142:1373-1382.
25. Berry MN, Edwards AM, Barritt GJ. Isolated hepatocytes preparation, properties and applications. Amsterdam: Elsevier, 1991:126-129.