Pneumocystis infection and the pathogenesis of chronic obstructive pulmonary disease

Immunologic Research

Volumn 50, Issue 2-3, 2011, Pages 175-180

  Norris, Karen A ^a   Morris, Alison ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

COPD; HIV; Pneumocystis; Pulmonary disease; SIV

Indexed keywords

CARBON MONOXIDE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; KEXIN; LYMPHOTOXIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; EMPHYSEMA; ENZYME LINKED IMMUNOSORBENT ASSAY; FORCED EXPIRATORY VOLUME; FUNGAL COLONIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNITY; INFECTION RESISTANCE; INFECTION RISK; INFECTION SENSITIVITY; INFLAMMATION; LUNG FUNCTION TEST; LUNG LAVAGE; MIXED INFECTION; NONHUMAN; PATHOGENESIS; PNEUMOCYSTIS JIROVECI; PNEUMOCYSTOSIS; POLYMERASE CHAIN REACTION; PRIMATE; PRIORITY JOURNAL; RISK ASSESSMENT; SIMIAN IMMUNODEFICIENCY VIRUS; SMOKING; T CELL DEPLETION; VIRUS LOAD;

ANIMALS; DISEASE MODELS, ANIMAL; HIV INFECTIONS; HUMANS; IMMUNOCOMPROMISED HOST; PNEUMOCYSTIS INFECTIONS; PNEUMOCYSTIS JIROVECII; PRIMATES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME;

EID: 79961172832     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-011-8218-x     Document Type: Article

References (60)

1. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. NHLBI/WHO workshop report. Bethesda, National Heart, Lung, and Blood Institute, April 2001; Update of the management sections. GOLD website ( www.goldcopd.com ).
2. GL Snider 1989 Chronic obstructive pulmonary disease: a definition and implications of structural determinants of airflow obstruction for epidemiology Am Rev Respir Dis 140 3 Pt 2 S3 S8 2675711 1:STN:280:DyaL1MzptFWqsg%3D%3D
3. PJ Barnes 2004 Mediators of chronic obstructive pulmonary disease Pharmacol Rev 56 4 515 548 15602009 10.1124/pr.56.4.2 1:CAS:528: DC%2BD2MXhtFWlt7s%3D (Pubitemid 39658462)
4. SD Shapiro 2002 Proteinases in chronic obstructive pulmonary disease Biochem Soc Trans 30 2 98 102 12023833 10.1042/BST0300098 1:CAS:528: DC%2BD38XjvVKhtL4%3D
5. JL Curtis CM Freeman JC Hogg 2007 The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research Proc Am Thorac Soc 4 7 512 521 17878463 10.1513/pats.200701-002FM 1:CAS:528:DC%2BD2sXht1Wnu7jJ (Pubitemid 47547845)
6. A Churg, et al. 2003 Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release Am J Respir Crit Care Med 167 8 1083 1089 12522030 10.1164/rccm.200212-1396OC (Pubitemid 36459653)
7. SD Shapiro 1999 The macrophage in chronic obstructive pulmonary disease Am J Respir Crit Care Med 160 5 Pt 2 S29 S32 10556166 1:STN:280: DC%2BD3c%2FksFSitw%3D%3D
8. AE Taylor, et al. 2010 Defective macrophage phagocytosis of bacteria in COPD Eur Respir J 35 5 1039 1047 19897561 10.1183/09031936.00036709 1:STN:280:DC%2BC3czgtFWmug%3D%3D
9. VM Keatings PJ Barnes 1997 Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects Am J Respir Crit Care Med 155 2 449 453 9032177 1:STN:280:DyaK2s7osVektw%3D%3D (Pubitemid 27085784)
10. JY Lacoste, et al. 1993 Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease J Allergy Clin Immunol 92 4 537 548 8409114 10.1016/0091-6749(93)90078-T 1:STN:280:DyaK2c%2FhsVSitw%3D%3D (Pubitemid 23317077)
11. TC O'Shaughnessy, et al. 1997 Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1 Am J Respir Crit Care Med 155 3 852 857 9117016 (Pubitemid 27133393)
12. JC Hogg, et al. 2004 The nature of small-airway obstruction in chronic obstructive pulmonary disease N Engl J Med 350 26 2645 2653 15215480 10.1056/NEJMoa032158 1:CAS:528:DC%2BD2cXltFGgur4%3D (Pubitemid 38787999)
13. JC Hogg 2001 Role of latent viral infections in chronic obstructive pulmonary disease and asthma Am J Respir Crit Care Med 164 10 Pt 2 S71 S75 11734471 1:STN:280:DC%2BD3MnovVSjsw%3D%3D
14. JC Hogg 2004 Pathophysiology of airflow limitation in chronic obstructive pulmonary disease Lancet 364 9435 709 721 15325838 10.1016/S0140-6736(04)16900- 6 (Pubitemid 39140629)
15. A Morris FC Sciurba KA Norris 2008 Pneumocystis: a novel pathogen in chronic obstructive pulmonary disease? Copd 5 1 43 51 18259974 10.1080/15412550701817656 (Pubitemid 351225519)
16. S Sethi 2000 Infectious etiology of acute exacerbations of chronic bronchitis Chest 117 5 Suppl 2 380S 385S 10843981 10.1378/chest.117.5-suppl-2. 380S 1:STN:280:DC%2BD3czgsFCntQ%3D%3D (Pubitemid 30314471)
17. S Sethi 2000 Bacterial infection and the pathogenesis of COPD Chest 117 5 Suppl 1 286S 291S 10843957 10.1378/chest.117.5-suppl-1.286S 1:STN:280:DC%2BD3czgsFChsQ%3D%3D (Pubitemid 30326996)
18. S Sethi TF Murphy 2008 Infection in the pathogenesis and course of chronic obstructive pulmonary disease N Engl J Med 359 22 2355 2365 19038881 10.1056/NEJMra0800353 1:CAS:528:DC%2BD1cXhsVehtbnJ
19. PT Diaz TL Clanton ER Pacht 1992 Emphysema-like pulmonary disease associated with human immunodeficiency virus infection Ann Intern Med 116 2 124 128 1727615 1:STN:280:DyaK38%2FovVWkuw%3D%3D
20. O Diaz, et al. 2000 Role of inspiratory capacity on exercise tolerance in COPD patients with and without tidal expiratory flow limitation at rest Eur Respir J 16 2 269 275 10968502 10.1034/j.1399-3003.2000.16b14.x 1:STN:280:DC%2BD3M%2FltVClsA%3D%3D (Pubitemid 30627482)
21. JE Kuhlman, et al. 1989 Premature bullous pulmonary damage in AIDS: CT diagnosis Radiology 173 1 23 26 2781013 1:STN:280:DyaL1MzoslKmtw%3D%3D (Pubitemid 19242398)
22. PT Diaz, et al. 2000 HIV infection increases susceptibility to smoking-induced emphysema Chest 117 5 Suppl 1 285S 10843956 10.1378/chest.117.5- suppl-1.285S (Pubitemid 30326994)
23. M Gelman, et al. 1999 Focal air trapping in patients with HIV infection: CT evaluation and correlation with pulmonary function test results AJR Am J Roentgenol 172 4 1033 1038 10587143 1:STN:280:DC%2BD3c%2Flt1ChtA%3D%3D (Pubitemid 29505635)
24. PT Diaz, et al. 2003 Respiratory symptoms among HIV-seropositive individuals Chest 123 6 1977 1982 12796177 10.1378/chest.123.6.1977 (Pubitemid 36706721)
25. CR O'Donnell, et al. 1988 Abnormal airway function in individuals with the acquired immunodeficiency syndrome Chest 94 5 945 948 3263260 10.1378/chest.94.5.945 (Pubitemid 18264633)
26. K Crothers, et al. 2006 Increased COPD among HIV-positive compared to HIV-negative veterans Chest 130 5 1326 1333 17099007 10.1378/chest.130.5.1326 (Pubitemid 44786723)
27. MP George, et al. 2009 Respiratory symptoms and airway obstruction in HIV-infected subjects in the HAART era PLoS One 4 7 e6328 19621086 10.1371/journal.pone.0006328
28. Gingo MR, et al. Pulmonary function abnormalities in HIV-infected patients during the current antiretroviral therapy era. Am J Respir Crit Care Med. 2010.
29. EF Fernandes, et al. 2005 Colonization with Pneumocystis in a simian model of AIDS results in chronic inflammation and airflow obstruction Am J Resp Crit Care Med 2 A867
30. A Morris, et al. 2008 Relationship of Pneumocystis antibody response to severity of chronic obstructive pulmonary disease Clin Infect Dis 47 7 e64 e68 18724825 10.1086/591701
31. A Morris, et al. 2009 Airway obstruction is increased in Pneumocystis-colonized human immunodeficiency virus-infected outpatients J Clin Microbiol 47 11 3773 3776 19759224 10.1128/JCM.01712-09
32. A Morris, et al. 2004 Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization Am J Respir Crit Care Med 170 4 408 413 15117741 10.1164/rccm.200401-094OC (Pubitemid 39214615)
33. AM Morris, et al. 2000 Permanent declines in pulmonary function following pneumonia in human immunodeficiency virus-infected persons. The pulmonary complications of HIV infection study group Am J Respir Crit Care Med 162 2 Pt 1 612 616 10934095 1:STN:280:DC%2BD3cvjtlCgtQ%3D%3D (Pubitemid 30647208)
34. KA Norris, et al. 2006 Pneumocystis colonization, airway inflammation, and pulmonary function decline in acquired immunodeficiency syndrome Immunol Res 36 1-3 175 187 17337778 10.1385/IR:36:1:175 1:CAS:528:DC%2BD2sXisVKnt78%3D (Pubitemid 46398594)
35. TW Shipley, et al. 2010 Persistent Pneumocystis colonization leads to the development of chronic obstructive pulmonary disease in a nonhuman primate model of AIDS J Infect Dis 202 2 302 312 20533880 10.1086/653485 1:CAS:528:DC%2BC3cXhtVSlu7zP
36. A Sing, et al. 1999 Pneumocystis carinii carriage in immunocompetent patients with primary pulmonary disorders as detected by single or nested PCR J Clin Microbiol 37 10 3409 3410 10488221 1:CAS:528:DyaK1MXmsFektbc%3D (Pubitemid 29455249)
37. M Probst, et al. 2000 Detection of Pneumocystis carinii DNA in patients with chronic lung diseases Eur J Clin Microbiol Infect Dis 19 8 644 645 11014633 10.1007/s100960000329 1:STN:280:DC%2BD3cvmt1GrsA%3D%3D
38. J Helweg-Larsen, et al. 2002 Detection of Pneumocystis DNA in samples from patients suspected of bacterial pneumonia-a case-control study BMC Infect Dis 2 1 28 12445330 10.1186/1471-2334-2-28 (Pubitemid 38750889)
39. E Calderon, et al. 2004 Pneumocystis jiroveci isolates with dihydropteroate synthase mutations in patients with chronic bronchitis Eur J Clin Microbiol Infect Dis 23 7 545 549 15175932 10.1007/s10096-004-1151-3 1:CAS:528:DC%2BD2cXls1Cjsb0%3D (Pubitemid 38998461)
40. A Morris, et al. 2008 Epidemiology and clinical significance of Pneumocystis colonization J Infect Dis 197 1 10 17 18171279 10.1086/523814 1:CAS:528:DC%2BD1cXhs1yqtLg%3D (Pubitemid 351263460)
41. A Morris, et al. 2004 Prevalence and clinical predictors of Pneumocystis colonization among HIV-infected men AIDS 18 5 793 798 15075515 10.1097/00002030-200403260-00011 (Pubitemid 38535008)
42. KF Board, et al. 2003 Experimental Pneumocystis carinii pneumonia in simian immunodeficiency virus-infected rhesus macaques J Infect Dis 187 4 576 588 12599074 10.1086/373997 (Pubitemid 36250021)
43. Patil SP, et al. Immune responses to Pneumocystis colonization and infection in a simian model of AIDS. J Eukaryot Microbiol. 2003; 50 Suppl: 661-2. (Pubitemid 38043062)
44. HM Kling, et al. 2009 Pneumocystis colonization in immunocompetent and simian immunodeficiency virus-infected cynomolgus macaques J Infect Dis 199 1 89 96 19014344 10.1086/595297
45. HM Kling, et al. 2010 Relationship of Pneumocystis jiroveci humoral immunity to prevention of colonization and chronic obstructive pulmonary disease in a primate model of HIV infection Infect Immun 78 10 4320 4330 20660609 10.1128/IAI.00507-10 1:CAS:528:DC%2BC3cXht12js73L
46. DA Croix, et al. 2002 Alterations in T lymphocyte profiles of bronchoalveolar lavage fluid from SIV- and Pneumocystis carinii-coinfected rhesus macaques AIDS Res Hum Retroviruses 18 5 391 401 11897041 10.1089/088922202753519179 (Pubitemid 34253139)
47. SV Joag 2000 Primate models of AIDS Microbes Infect 2 2 223 229 10742694 10.1016/S1286-4579(00)00266-5 1:STN:280:DC%2BD3c3gvFKrug%3D%3D (Pubitemid 30154711)
48. George MP, et al. Pulmonary vascular lesions are common in SIV- and SHIV-env-infected macaques. AIDS Res Hum Retroviruses. 2010.
49. J Guillot, et al. 2004 Phylogenetic relationships among Pneumocystis from Asian macaques inferred from mitochondrial rRNA sequences Mol Phylogenet Evol 31 3 988 996 15120396 10.1016/j.ympev.2003.10.022 1:CAS:528:DC%2BD2cXjs1alsLg%3D (Pubitemid 38610971)
50. Kling H, Shipley T, Norris K. Abnormalities in peripheral blood B lymphocyte populations in SHIV89.6P-infected macaques. Comp Med. 2011 (In press).
51. D Kuhrt, et al. 2010 Evidence of early B-cell dysregulation in simian immunodeficiency virus infection: rapid depletion of naive and memory B-cell subsets with delayed reconstitution of the naive B-cell population J Virol 84 5 2466 2476 20032183 10.1128/JVI.01966-09 1:CAS:528:DC%2BC3cXisVCjtbY%3D
52. A Morris 2008 Is there anything new in Pneumocystis jirovecii pneumonia? Changes in P. jirovecii pneumonia over the course of the AIDS epidemic Clin Infect Dis 46 4 634 636 18190280 10.1086/526779 (Pubitemid 351263507)
53. A Morris, et al. 2004 Current epidemiology of Pneumocystis pneumonia Emerg Infect Dis 10 10 1713 1720 15504255 (Pubitemid 39319360)
54. KM Empey, et al. 2004 Passive immunization of neonatal mice against Pneumocystis carinii f. sp. muris enhances control of infection without stimulating inflammation Infect Immun 72 11 6211 6220 15501746 10.1128/IAI.72.11.6211-6220.2004 1:CAS:528:DC%2BD2cXpsFeltb8%3D (Pubitemid 39425397)
55. FE Lund, et al. 2006 B cells are required for generation of protective effector and memory CD4 cells in response to Pneumocystis lung infection J Immunol 176 10 6147 6154 16670323 1:CAS:528:DC%2BD28XktVWgu78%3D
56. FE Lund, et al. 2003 Clearance of Pneumocystis carinii in mice is dependent on B cells but not on P carinii-specific antibody J Immunol 171 3 1423 1430 12874234 1:CAS:528:DC%2BD3sXlsFylt70%3D (Pubitemid 36900076)
57. C Demanche, et al. 2005 Molecular and serological evidence of Pneumocystis circulation in a social organization of healthy macaques (Macaca fascicularis) Microbiology 151 Pt 9 3117 3125 16151222 10.1099/mic.0.28059-0 1:CAS:528:DC%2BD2MXhtVKrurjF (Pubitemid 41309582)
58. M Zheng, et al. 2005 CD4+ T cell-independent DNA vaccination against opportunistic infections J Clin Invest 115 12 3536 3544 16308571 10.1172/JCI26306 1:CAS:528:DC%2BD2MXhtlSqtLvJ (Pubitemid 43121841)
59. J Wells, et al. 2006 Active immunization against Pneumocystis carinii with a recombinant P. carinii antigen Infect Immun 74 4 2446 2448 16552076 10.1128/IAI.74.4.2446-2448.2006 1:CAS:528:DC%2BD28XjsVWht74%3D
60. Gingo MR, et al. Serologic responses to Pneumocystis proteins in human immunodeficiency virus patients with and without Pneumocystis jirovecii pneumonia. J Acquir Immune Defic Syndr. 2011.