메뉴 건너뛰기




Volumn 6, Issue 8, 2011, Pages

In Situ dividing and phagocytosing retinal microglia express Nestin, Vimentin, and NG2 In Vivo

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CALCIUM BINDING PROTEIN; CALCIUM BINDING PROTEIN IBA1; CD11B ANTIGEN; DOUBLECORTIN; FLUOROGOLD; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN; PROTEOCHONDROITIN SULFATE; PROTEOCHONDROITIN SULFATE NG2; UNCLASSIFIED DRUG; VIMENTIN; ANTIGEN; CHONDROITIN SULFATE PROTEOGLYCAN 4; INTERMEDIATE FILAMENT PROTEIN; NERVE PROTEIN; PROTEOGLYCAN;

EID: 79961157898     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022408     Document Type: Article
Times cited : (52)

References (99)
  • 1
    • 0029434439 scopus 로고
    • The microglial cell. A historical review
    • Barron KD, (1995) The microglial cell. A historical review. J Neurol Sci 134 (Suppl): 57-68.
    • (1995) J Neurol Sci , vol.134 , Issue.SUPPL. , pp. 57-68
    • Barron, K.D.1
  • 2
    • 0036933302 scopus 로고    scopus 로고
    • Distribution, markers, and functions of retinal microglia
    • Chen L, Yang P, Kijlstra A, (2002) Distribution, markers, and functions of retinal microglia. Ocul Immunol Inflamm 10: 27-39.
    • (2002) Ocul Immunol Inflamm , vol.10 , pp. 27-39
    • Chen, L.1    Yang, P.2    Kijlstra, A.3
  • 3
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A, Kirchhoff F, Helmchen F, (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308: 1314-1318.
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 4
    • 0029270425 scopus 로고
    • Microglia, the first line of defence in brain pathologies
    • Kreutzberg GW, (1995) Microglia, the first line of defence in brain pathologies. Arzneimittelforschung 45: 357-360.
    • (1995) Arzneimittelforschung , vol.45 , pp. 357-360
    • Kreutzberg, G.W.1
  • 6
    • 0036849018 scopus 로고    scopus 로고
    • Microglia as a source and target of cytokines
    • Hanisch UKL, (2002) Microglia as a source and target of cytokines. Glia 40: 140-155.
    • (2002) Glia , vol.40 , pp. 140-155
    • Hanisch, U.K.L.1
  • 8
    • 0028310855 scopus 로고
    • Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats
    • Berkelaar M, Clarke DB, Wang YC, Bray GM, Aguayo AJ, (1994) Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci 14: 4368-4374.
    • (1994) J Neurosci , vol.14 , pp. 4368-4374
    • Berkelaar, M.1    Clarke, D.B.2    Wang, Y.C.3    Bray, G.M.4    Aguayo, A.J.5
  • 9
    • 0027463379 scopus 로고
    • Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats
    • Villegas-Perez MP, Vidal-Sanz M, Rasminsky M, Bray GM, Aguayo AJ, (1993) Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats. J Neurobiol 24: 23-36.
    • (1993) J Neurobiol , vol.24 , pp. 23-36
    • Villegas-Perez, M.P.1    Vidal-Sanz, M.2    Rasminsky, M.3    Bray, G.M.4    Aguayo, A.J.5
  • 10
    • 77952484467 scopus 로고    scopus 로고
    • Proliferative response of microglia and macrophages in the adult mouse eye after optic nerve lesion
    • Wohl SG, Schmeer CW, Witte OW, Isenmann S, (2010) Proliferative response of microglia and macrophages in the adult mouse eye after optic nerve lesion. Invest Ophthalmol Vis Sci 51: 2686-2696.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 2686-2696
    • Wohl, S.G.1    Schmeer, C.W.2    Witte, O.W.3    Isenmann, S.4
  • 11
    • 0026356353 scopus 로고
    • The Relationship of Microglial Cells to Dying Neurons During Natural Neuronal Cell Death and Axotomy-induced Degeneration of the Rat Retina
    • Thanos S, (1991) The Relationship of Microglial Cells to Dying Neurons During Natural Neuronal Cell Death and Axotomy-induced Degeneration of the Rat Retina. Eur J Neurosci 3: 1189-1207.
    • (1991) Eur J Neurosci , vol.3 , pp. 1189-1207
    • Thanos, S.1
  • 12
    • 0041837517 scopus 로고    scopus 로고
    • Characterization of activated retinal microglia following optic axotomy
    • Zhang C, Tso MO, (2003) Characterization of activated retinal microglia following optic axotomy. J Neurosci Res 73: 840-845.
    • (2003) J Neurosci Res , vol.73 , pp. 840-845
    • Zhang, C.1    Tso, M.O.2
  • 13
    • 0942265578 scopus 로고    scopus 로고
    • Neuroprotective effect of inosine on axotomized retinal ganglion cells in adult rats
    • Hou B, You SW, Wu MM, Kuang F, Liu HL, et al. (2004) Neuroprotective effect of inosine on axotomized retinal ganglion cells in adult rats. Invest Ophthalmol Vis Sci 45: 662-667.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 662-667
    • Hou, B.1    You, S.W.2    Wu, M.M.3    Kuang, F.4    Liu, H.L.5
  • 15
    • 0032976182 scopus 로고    scopus 로고
    • Laminar restriction of retinal macrophagic response to optic nerve axotomy in the rat
    • Garcia-Valenzuela E, Sharma SC, (1999) Laminar restriction of retinal macrophagic response to optic nerve axotomy in the rat. J Neurobiol 40: 55-66.
    • (1999) J Neurobiol , vol.40 , pp. 55-66
    • Garcia-Valenzuela, E.1    Sharma, S.C.2
  • 16
    • 0033523481 scopus 로고    scopus 로고
    • Expression of nestin after traumatic brain injury in rat brain
    • Sahin Kaya S, Mahmood A, Li Y, Yavuz E, Chopp M, (1999) Expression of nestin after traumatic brain injury in rat brain. Brain Res 840: 153-157.
    • (1999) Brain Res , vol.840 , pp. 153-157
    • Sahin Kaya, S.1    Mahmood, A.2    Li, Y.3    Yavuz, E.4    Chopp, M.5
  • 17
    • 0037440473 scopus 로고    scopus 로고
    • Early oligodendrocyte progenitor cells in the human fetal telencephalon
    • Rakic S, Zecevic N, (2003) Early oligodendrocyte progenitor cells in the human fetal telencephalon. Glia 41: 117-127.
    • (2003) Glia , vol.41 , pp. 117-127
    • Rakic, S.1    Zecevic, N.2
  • 18
    • 77249172141 scopus 로고    scopus 로고
    • Induced NG2 expressing microglia in the facial motor nucleus after facial nerve axotomy
    • Zhu L, Lu J, Tay SS, Jiang H, He BP, (2010) Induced NG2 expressing microglia in the facial motor nucleus after facial nerve axotomy. Neuroscience.
    • (2010) Neuroscience
    • Zhu, L.1    Lu, J.2    Tay, S.S.3    Jiang, H.4    He, B.P.5
  • 19
    • 37349108615 scopus 로고    scopus 로고
    • The ameboid phenotype of NG2 (+) cells in the region of apoptotic dentate granule neurons in trimethyltin intoxicated mice shares antigen properties with microglia/macrophages
    • Fiedorowicz A, Figiel I, Zaremba M, Dzwonek K, Oderfeld-Nowak B, (2008) The ameboid phenotype of NG2 (+) cells in the region of apoptotic dentate granule neurons in trimethyltin intoxicated mice shares antigen properties with microglia/macrophages. Glia 56: 209-222.
    • (2008) Glia , vol.56 , pp. 209-222
    • Fiedorowicz, A.1    Figiel, I.2    Zaremba, M.3    Dzwonek, K.4    Oderfeld-Nowak, B.5
  • 20
    • 0033198806 scopus 로고    scopus 로고
    • Expression of a homologue of rat NG2 on human microglia
    • Pouly S, Becher B, Blain M, Antel JP, (1999) Expression of a homologue of rat NG2 on human microglia. Glia 27: 259-268.
    • (1999) Glia , vol.27 , pp. 259-268
    • Pouly, S.1    Becher, B.2    Blain, M.3    Antel, J.P.4
  • 21
    • 33646248378 scopus 로고    scopus 로고
    • NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains
    • Yokoyama A, Sakamoto A, Kameda K, Imai Y, Tanaka J, (2006) NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains. Glia 53: 754-768.
    • (2006) Glia , vol.53 , pp. 754-768
    • Yokoyama, A.1    Sakamoto, A.2    Kameda, K.3    Imai, Y.4    Tanaka, J.5
  • 22
    • 0030338275 scopus 로고    scopus 로고
    • The NG2 chondroitin sulfate proteoglycan: a multifunctional proteoglycan associated with immature cells
    • Levine JM, Nishiyama A, (1996) The NG2 chondroitin sulfate proteoglycan: a multifunctional proteoglycan associated with immature cells. Perspect Dev Neurobiol 3: 245-259.
    • (1996) Perspect Dev Neurobiol , vol.3 , pp. 245-259
    • Levine, J.M.1    Nishiyama, A.2
  • 23
    • 77952423805 scopus 로고    scopus 로고
    • NG2 cells: Properties, progeny and origin
    • Trotter J, Karram K, Nishiyama A, (2010) NG2 cells: Properties, progeny and origin. Brain Res Rev 63: 72-82.
    • (2010) Brain Res Rev , vol.63 , pp. 72-82
    • Trotter, J.1    Karram, K.2    Nishiyama, A.3
  • 24
    • 0346655312 scopus 로고    scopus 로고
    • Microglia, a potential source of neurons, astrocytes, and oligodendrocytes
    • Yokoyama A, Yang L, Itoh S, Mori K, Tanaka JL, (2004) Microglia, a potential source of neurons, astrocytes, and oligodendrocytes. Glia 45: 96-104.
    • (2004) Glia , vol.45 , pp. 96-104
    • Yokoyama, A.1    Yang, L.2    Itoh, S.3    Mori, K.4    Tanaka, J.L.5
  • 25
    • 68549085148 scopus 로고    scopus 로고
    • Optic nerve lesion increases cell proliferation and nestin expression in the adult mouse eye in vivo
    • Wohl SG, Schmeer CW, Kretz A, Witte OW, Isenmann S, (2009) Optic nerve lesion increases cell proliferation and nestin expression in the adult mouse eye in vivo. Exp Neurol 219: 175-186.
    • (2009) Exp Neurol , vol.219 , pp. 175-186
    • Wohl, S.G.1    Schmeer, C.W.2    Kretz, A.3    Witte, O.W.4    Isenmann, S.5
  • 26
    • 0033230207 scopus 로고    scopus 로고
    • Pericytes and periendothelial cells of brain parenchyma vessels co-express aminopeptidase N, aminopeptidase A, and nestin
    • Alliot F, Rutin J, Leenen PJ, Pessac B, (1999) Pericytes and periendothelial cells of brain parenchyma vessels co-express aminopeptidase N, aminopeptidase A, and nestin. J Neurosci Res 58: 367-378.
    • (1999) J Neurosci Res , vol.58 , pp. 367-378
    • Alliot, F.1    Rutin, J.2    Leenen, P.J.3    Pessac, B.4
  • 28
    • 0033807429 scopus 로고    scopus 로고
    • Diversity within pericytes
    • Sims DE, (2000) Diversity within pericytes. Clin Exp Pharmacol Physiol 27: 842-846.
    • (2000) Clin Exp Pharmacol Physiol , vol.27 , pp. 842-846
    • Sims, D.E.1
  • 30
    • 41149129348 scopus 로고    scopus 로고
    • Nestin expression in repopulating mesangial cells promotes their proliferation
    • Daniel C, Albrecht H, Ludke A, Hugo C, (2008) Nestin expression in repopulating mesangial cells promotes their proliferation. Lab Invest 88: 387-397.
    • (2008) Lab Invest , vol.88 , pp. 387-397
    • Daniel, C.1    Albrecht, H.2    Ludke, A.3    Hugo, C.4
  • 31
    • 33749165460 scopus 로고    scopus 로고
    • Signals from embryonic fibroblasts induce adult intestinal epithelial cells to form nestin-positive cells with proliferation and multilineage differentiation capacity in vitro
    • Wiese C, Rolletschek A, Kania G, Navarrete-Santos A, Anisimov SV, et al. (2006) Signals from embryonic fibroblasts induce adult intestinal epithelial cells to form nestin-positive cells with proliferation and multilineage differentiation capacity in vitro. Stem Cells 24: 2085-2097.
    • (2006) Stem Cells , vol.24 , pp. 2085-2097
    • Wiese, C.1    Rolletschek, A.2    Kania, G.3    Navarrete-Santos, A.4    Anisimov, S.V.5
  • 32
    • 44449098145 scopus 로고    scopus 로고
    • Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors
    • Sunabori T, Tokunaga A, Nagai T, Sawamoto K, Okabe M, et al. (2008) Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors. J Cell Sci 121: 1204-1212.
    • (2008) J Cell Sci , vol.121 , pp. 1204-1212
    • Sunabori, T.1    Tokunaga, A.2    Nagai, T.3    Sawamoto, K.4    Okabe, M.5
  • 33
    • 0035844275 scopus 로고    scopus 로고
    • Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase
    • Sahlgren CM, Mikhailov A, Hellman J, Chou YH, Lendahl U, et al. (2001) Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase. J Biol Chem 276: 16456-16463.
    • (2001) J Biol Chem , vol.276 , pp. 16456-16463
    • Sahlgren, C.M.1    Mikhailov, A.2    Hellman, J.3    Chou, Y.H.4    Lendahl, U.5
  • 34
    • 30744458323 scopus 로고    scopus 로고
    • Simvastatin promotes heat shock protein 27 expression and Akt activation in the rat retina and protects axotomized retinal ganglion cells in vivo
    • Kretz A, Schmeer C, Tausch S, Isenmann S, (2006) Simvastatin promotes heat shock protein 27 expression and Akt activation in the rat retina and protects axotomized retinal ganglion cells in vivo. Neurobiol Dis 21: 421-430.
    • (2006) Neurobiol Dis , vol.21 , pp. 421-430
    • Kretz, A.1    Schmeer, C.2    Tausch, S.3    Isenmann, S.4
  • 35
    • 0012205849 scopus 로고
    • Old dyes for new scopes: the phagocytosis-dependent long-term fluorescence labelling of microglial cells in vivo
    • Thanos S, Kacza J, Seeger J, Mey J, (1994) Old dyes for new scopes: the phagocytosis-dependent long-term fluorescence labelling of microglial cells in vivo. Trends Neurosci 17: 177-182.
    • (1994) Trends Neurosci , vol.17 , pp. 177-182
    • Thanos, S.1    Kacza, J.2    Seeger, J.3    Mey, J.4
  • 36
    • 0033780270 scopus 로고    scopus 로고
    • Migration of phagocytotic cells and development of the murine intraretinal microglial network: an in vivo study using fluorescent dyes
    • Bodeutsch N, Thanos S, (2000) Migration of phagocytotic cells and development of the murine intraretinal microglial network: an in vivo study using fluorescent dyes. Glia 32: 91-101.
    • (2000) Glia , vol.32 , pp. 91-101
    • Bodeutsch, N.1    Thanos, S.2
  • 37
    • 0242569638 scopus 로고    scopus 로고
    • Purification of astrocytes from adult human optic nerve heads by immunopanning
    • Yang P, Hernandez MR, (2003) Purification of astrocytes from adult human optic nerve heads by immunopanning. Brain Res Brain Res Protoc 12: 67-76.
    • (2003) Brain Res Brain Res Protoc , vol.12 , pp. 67-76
    • Yang, P.1    Hernandez, M.R.2
  • 39
  • 40
    • 0022654730 scopus 로고
    • Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3
    • Robinson AP, White TM, Mason DW, (1986) Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. Immunology 57: 239-247.
    • (1986) Immunology , vol.57 , pp. 239-247
    • Robinson, A.P.1    White, T.M.2    Mason, D.W.3
  • 41
    • 0021969667 scopus 로고
    • The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3
    • Dijkstra CD, Dopp EA, Joling P, Kraal G, (1985) The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 54: 589-599.
    • (1985) Immunology , vol.54 , pp. 589-599
    • Dijkstra, C.D.1    Dopp, E.A.2    Joling, P.3    Kraal, G.4
  • 42
    • 0028364108 scopus 로고
    • Demonstration of poly-N-acetyl lactosamine residues in ameboid and ramified microglial cells in rat brain by tomato lectin binding
    • Acarin L, Vela JM, Gonzalez B, Castellano B, (1994) Demonstration of poly-N-acetyl lactosamine residues in ameboid and ramified microglial cells in rat brain by tomato lectin binding. J Histochem Cytochem 42: 1033-1041.
    • (1994) J Histochem Cytochem , vol.42 , pp. 1033-1041
    • Acarin, L.1    Vela, J.M.2    Gonzalez, B.3    Castellano, B.4
  • 44
    • 79952354608 scopus 로고    scopus 로고
    • Microglia - insights into immune system structure, function, and reactivity in the central nervous system
    • Wirenfeldt M, Babcock AA, Vinters HV, (2011) Microglia- insights into immune system structure, function, and reactivity in the central nervous system. Histol Histopathol 26: 519-530.
    • (2011) Histol Histopathol , vol.26 , pp. 519-530
    • Wirenfeldt, M.1    Babcock, A.A.2    Vinters, H.V.3
  • 45
    • 0022408894 scopus 로고
    • Identification of major cell classes in the developing mammalian nervous system
    • Hockfield S, McKay RD, (1985) Identification of major cell classes in the developing mammalian nervous system. J Neurosci 5: 3310-3328.
    • (1985) J Neurosci , vol.5 , pp. 3310-3328
    • Hockfield, S.1    McKay, R.D.2
  • 46
    • 0025190642 scopus 로고
    • CNS stem cells express a new class of intermediate filament protein
    • Lendahl U, Zimmerman LB, McKay RD, (1990) CNS stem cells express a new class of intermediate filament protein. Cell 60: 585-595.
    • (1990) Cell , vol.60 , pp. 585-595
    • Lendahl, U.1    Zimmerman, L.B.2    McKay, R.D.3
  • 47
    • 0023783018 scopus 로고
    • The microglial cytoskeleton: vimentin is localized within activated cells in situ
    • Graeber MB, Streit WJ, Kreutzberg GW, (1988) The microglial cytoskeleton: vimentin is localized within activated cells in situ. J Neurocytol 17: 573-580.
    • (1988) J Neurocytol , vol.17 , pp. 573-580
    • Graeber, M.B.1    Streit, W.J.2    Kreutzberg, G.W.3
  • 49
    • 0030851891 scopus 로고    scopus 로고
    • Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat
    • Isenmann S, Wahl C, Krajewski S, Reed JC, Bähr M, (1997) Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat. Eur J Neurosci 9: 1763-1772.
    • (1997) Eur J Neurosci , vol.9 , pp. 1763-1772
    • Isenmann, S.1    Wahl, C.2    Krajewski, S.3    Reed, J.C.4    Bähr, M.5
  • 50
    • 38449115858 scopus 로고    scopus 로고
    • Proliferation and expression of progenitor and mature retinal phenotypes in the adult mammalian ciliary body after retinal ganglion cell injury
    • Nickerson PE, Emsley JG, Myers T, Clarke DB, (2007) Proliferation and expression of progenitor and mature retinal phenotypes in the adult mammalian ciliary body after retinal ganglion cell injury. Invest Ophthalmol Vis Sci 48: 5266-5275.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 5266-5275
    • Nickerson, P.E.1    Emsley, J.G.2    Myers, T.3    Clarke, D.B.4
  • 51
    • 16344396507 scopus 로고    scopus 로고
    • Nestin structure and predicted function in cellular cytoskeletal organisation
    • Michalczyk K, Ziman M, (2005) Nestin structure and predicted function in cellular cytoskeletal organisation. Histol Histopathol 20: 665-671.
    • (2005) Histol Histopathol , vol.20 , pp. 665-671
    • Michalczyk, K.1    Ziman, M.2
  • 53
    • 0034643271 scopus 로고    scopus 로고
    • Identification of neural progenitors in the adult mammalian eye
    • Ahmad I, Tang L, Pham H, (2000) Identification of neural progenitors in the adult mammalian eye. Biochem Biophys Res Commun 270: 517-521.
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 517-521
    • Ahmad, I.1    Tang, L.2    Pham, H.3
  • 54
    • 33750524426 scopus 로고    scopus 로고
    • Nestin expression in Muller glial cells in postnatal rat retina and its upregulation following optic nerve transection
    • Xue LP, Lu J, Cao Q, Kaur C, Ling EA, (2006) Nestin expression in Muller glial cells in postnatal rat retina and its upregulation following optic nerve transection. Neuroscience 143: 117-127.
    • (2006) Neuroscience , vol.143 , pp. 117-127
    • Xue, L.P.1    Lu, J.2    Cao, Q.3    Kaur, C.4    Ling, E.A.5
  • 55
    • 1642462114 scopus 로고    scopus 로고
    • The neurogenic competence of progenitors from the postnatal rat retina in vitro
    • Engelhardt M, Wachs FP, Couillard-Despres S, Aigner L, (2004) The neurogenic competence of progenitors from the postnatal rat retina in vitro. Exp Eye Res 78: 1025-1036.
    • (2004) Exp Eye Res , vol.78 , pp. 1025-1036
    • Engelhardt, M.1    Wachs, F.P.2    Couillard-Despres, S.3    Aigner, L.4
  • 56
    • 0028058750 scopus 로고
    • Immunomorphologic studies of macrophages and MHC class II-positive dendritic cells in the iris and ciliary body of the rat, mouse, and human eye
    • McMenamin PG, Crewe J, Morrison S, Holt PG, (1994) Immunomorphologic studies of macrophages and MHC class II-positive dendritic cells in the iris and ciliary body of the rat, mouse, and human eye. Invest Ophthalmol Vis Sci 35: 3234-3250.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3234-3250
    • McMenamin, P.G.1    Crewe, J.2    Morrison, S.3    Holt, P.G.4
  • 57
    • 0032955311 scopus 로고    scopus 로고
    • Dendritic cells and macrophages in the uveal tract of the normal mouse eye
    • McMenamin PG, (1999) Dendritic cells and macrophages in the uveal tract of the normal mouse eye. Br J Ophthalmol 83: 598-604.
    • (1999) Br J Ophthalmol , vol.83 , pp. 598-604
    • McMenamin, P.G.1
  • 58
    • 0038681081 scopus 로고    scopus 로고
    • Intermediate filament nestin expressions in human cord blood monocytes (HCMNCs)
    • Ha Y, Lee JE, Kim KN, Cho YE, Yoon DH, (2003) Intermediate filament nestin expressions in human cord blood monocytes (HCMNCs). Acta Neurochir (Wien) 145: 483-487.
    • (2003) Acta Neurochir (Wien) , vol.145 , pp. 483-487
    • Ha, Y.1    Lee, J.E.2    Kim, K.N.3    Cho, Y.E.4    Yoon, D.H.5
  • 59
    • 0031609393 scopus 로고    scopus 로고
    • Immunohistochemical detection of intermediate filament nestin
    • Mokry J, Nemecek S, (1998) Immunohistochemical detection of intermediate filament nestin. Acta Medica (Hradec Kralove) 41: 73-80.
    • (1998) Acta Medica (Hradec Kralove) , vol.41 , pp. 73-80
    • Mokry, J.1    Nemecek, S.2
  • 60
    • 77955860592 scopus 로고    scopus 로고
    • The neural stem/progenitor cell marker nestin is expressed in proliferative endothelial cells, but not in mature vasculature
    • Suzuki S, Namiki J, Shibata S, Mastuzaki Y, Okano H, (2010) The neural stem/progenitor cell marker nestin is expressed in proliferative endothelial cells, but not in mature vasculature. J Histochem Cytochem 58: 721-730.
    • (2010) J Histochem Cytochem , vol.58 , pp. 721-730
    • Suzuki, S.1    Namiki, J.2    Shibata, S.3    Mastuzaki, Y.4    Okano, H.5
  • 61
    • 34247603570 scopus 로고    scopus 로고
    • Rat retinal microglial cells under normal conditions, after optic nerve section, and after optic nerve section and intravitreal injection of trophic factors or macrophage inhibitory factor
    • Sobrado-Calvo P, Vidal-Sanz M, Villegas-Perez MP, (2007) Rat retinal microglial cells under normal conditions, after optic nerve section, and after optic nerve section and intravitreal injection of trophic factors or macrophage inhibitory factor. J Comp Neurol 501: 866-878.
    • (2007) J Comp Neurol , vol.501 , pp. 866-878
    • Sobrado-Calvo, P.1    Vidal-Sanz, M.2    Villegas-Perez, M.P.3
  • 62
    • 25444436001 scopus 로고    scopus 로고
    • Multilayered retinal microglial response to optic nerve transection in rats
    • Garcia-Valenzuela E, Sharma SC, Pina AL, (2005) Multilayered retinal microglial response to optic nerve transection in rats. Mol Vis 11: 225-231.
    • (2005) Mol Vis , vol.11 , pp. 225-231
    • Garcia-Valenzuela, E.1    Sharma, S.C.2    Pina, A.L.3
  • 63
    • 77955086793 scopus 로고    scopus 로고
    • Nestin is essential for mitogen-stimulated proliferation of neural progenitor cells
    • Xue XJ, Yuan XB, (2010) Nestin is essential for mitogen-stimulated proliferation of neural progenitor cells. Mol Cell Neurosci 45: 26-36.
    • (2010) Mol Cell Neurosci , vol.45 , pp. 26-36
    • Xue, X.J.1    Yuan, X.B.2
  • 64
    • 33744942118 scopus 로고    scopus 로고
    • Long-lasting coexpression of nestin and glial fibrillary acidic protein in primary cultures of astroglial cells with a major participation of nestin(+)/GFAP(-) cells in cell proliferation
    • Sergent-Tanguy S, Michel DC, Neveu I, Naveilhan P, (2006) Long-lasting coexpression of nestin and glial fibrillary acidic protein in primary cultures of astroglial cells with a major participation of nestin(+)/GFAP(-) cells in cell proliferation. J Neurosci Res 83: 1515-1524.
    • (2006) J Neurosci Res , vol.83 , pp. 1515-1524
    • Sergent-Tanguy, S.1    Michel, D.C.2    Neveu, I.3    Naveilhan, P.4
  • 65
    • 33845982912 scopus 로고    scopus 로고
    • Reactive changes of retinal astrocytes and Muller glial cells in kainate-induced neuroexcitotoxicity
    • Chang ML, Wu CH, Jiang-Shieh YF, Shieh JY, Wen CY, (2007) Reactive changes of retinal astrocytes and Muller glial cells in kainate-induced neuroexcitotoxicity. J Anat 210: 54-65.
    • (2007) J Anat , vol.210 , pp. 54-65
    • Chang, M.L.1    Wu, C.H.2    Jiang-Shieh, Y.F.3    Shieh, J.Y.4    Wen, C.Y.5
  • 66
    • 0032895971 scopus 로고    scopus 로고
    • Cell proliferation and nestin expression in the ependyma of the adult rat spinal cord after injury
    • Namiki J, Tator CH, (1999) Cell proliferation and nestin expression in the ependyma of the adult rat spinal cord after injury. J Neuropathol Exp Neurol 58: 489-498.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 489-498
    • Namiki, J.1    Tator, C.H.2
  • 67
    • 77949501560 scopus 로고    scopus 로고
    • Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis
    • Chen HL, Yuh CH, Wu KK, (2010) Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis. PLoS One 5: e9318.
    • (2010) PLoS One , vol.5
    • Chen, H.L.1    Yuh, C.H.2    Wu, K.K.3
  • 68
    • 0030979469 scopus 로고    scopus 로고
    • Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain
    • Doetsch F, Garcia-Verdugo JM, Alvarez-Buylla A, (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci 17: 5046-5061.
    • (1997) J Neurosci , vol.17 , pp. 5046-5061
    • Doetsch, F.1    Garcia-Verdugo, J.M.2    Alvarez-Buylla, A.3
  • 70
    • 0037815270 scopus 로고    scopus 로고
    • Muller cells express the neuronal progenitor cell marker nestin in both differentiated and undifferentiated human foetal retina
    • Walcott JC, Provis JML, (2003) Muller cells express the neuronal progenitor cell marker nestin in both differentiated and undifferentiated human foetal retina. Clin Experiment Ophthalmol 31: 246-249.
    • (2003) Clin Experiment Ophthalmol , vol.31 , pp. 246-249
    • Walcott, J.C.1    Provis, J.M.L.2
  • 71
    • 34248377351 scopus 로고    scopus 로고
    • Characteristics of progenitor cells derived from adult ciliary body in mouse, rat, and human eyes
    • Xu H, Sta Iglesia DD, Kielczewski JL, Valenta DF, Pease ME, et al. (2007) Characteristics of progenitor cells derived from adult ciliary body in mouse, rat, and human eyes. Invest Ophthalmol Vis Sci 48: 1674-1682.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 1674-1682
    • Xu, H.1    Sta Iglesia, D.D.2    Kielczewski, J.L.3    Valenta, D.F.4    Pease, M.E.5
  • 72
    • 0038709375 scopus 로고    scopus 로고
    • Nestin promotes the phosphorylation-dependent disassembly of vimentin intermediate filaments during mitosis
    • Chou YH, Khuon S, Herrmann H, Goldman RD, (2003) Nestin promotes the phosphorylation-dependent disassembly of vimentin intermediate filaments during mitosis. Mol Biol Cell 14: 1468-1478.
    • (2003) Mol Biol Cell , vol.14 , pp. 1468-1478
    • Chou, Y.H.1    Khuon, S.2    Herrmann, H.3    Goldman, R.D.4
  • 73
    • 0033515454 scopus 로고    scopus 로고
    • A high molecular weight intermediate filament-associated protein in BHK-21 cells is nestin, a type VI intermediate filament protein. Limited co-assembly in vitro to form heteropolymers with type III vimentin and type IV alpha-internexin
    • Steinert PM, Chou YH, Prahlad V, Parry DA, Marekov LN, et al. (1999) A high molecular weight intermediate filament-associated protein in BHK-21 cells is nestin, a type VI intermediate filament protein. Limited co-assembly in vitro to form heteropolymers with type III vimentin and type IV alpha-internexin. J Biol Chem 274: 9881-9890.
    • (1999) J Biol Chem , vol.274 , pp. 9881-9890
    • Steinert, P.M.1    Chou, Y.H.2    Prahlad, V.3    Parry, D.A.4    Marekov, L.N.5
  • 74
    • 0034950456 scopus 로고    scopus 로고
    • Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion
    • Bu J, Akhtar N, Nishiyama A, (2001) Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion. Glia 34: 296-310.
    • (2001) Glia , vol.34 , pp. 296-310
    • Bu, J.1    Akhtar, N.2    Nishiyama, A.3
  • 75
    • 0030063699 scopus 로고    scopus 로고
    • Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain
    • Nishiyama A, Lin XH, Giese N, Heldin CH, Stallcup WB, (1996) Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. J Neurosci Res 43: 299-314.
    • (1996) J Neurosci Res , vol.43 , pp. 299-314
    • Nishiyama, A.1    Lin, X.H.2    Giese, N.3    Heldin, C.H.4    Stallcup, W.B.5
  • 76
    • 33845985597 scopus 로고    scopus 로고
    • Polydendrocytes: NG2 cells with many roles in development and repair of the CNS
    • Nishiyama A, (2007) Polydendrocytes: NG2 cells with many roles in development and repair of the CNS. Neuroscientist 13: 62-76.
    • (2007) Neuroscientist , vol.13 , pp. 62-76
    • Nishiyama, A.1
  • 77
    • 0242725514 scopus 로고    scopus 로고
    • Synantocytes: new functions for novel NG2 expressing glia
    • Butt AM, Kiff J, Hubbard P, Berry M, (2002) Synantocytes: new functions for novel NG2 expressing glia. J Neurocytol 31: 551-565.
    • (2002) J Neurocytol , vol.31 , pp. 551-565
    • Butt, A.M.1    Kiff, J.2    Hubbard, P.3    Berry, M.4
  • 78
    • 0023404197 scopus 로고
    • Bipotential glial precursor cells of the optic nerve express the NG2 proteoglycan
    • Stallcup WB, Beasley L, (1987) Bipotential glial precursor cells of the optic nerve express the NG2 proteoglycan. J Neurosci 7: 2737-2744.
    • (1987) J Neurosci , vol.7 , pp. 2737-2744
    • Stallcup, W.B.1    Beasley, L.2
  • 79
    • 0024555756 scopus 로고
    • Identification of an adult-specific glial progenitor cell
    • Wolswijk G, Noble M, (1989) Identification of an adult-specific glial progenitor cell. Development 105: 387-400.
    • (1989) Development , vol.105 , pp. 387-400
    • Wolswijk, G.1    Noble, M.2
  • 80
    • 31544464652 scopus 로고    scopus 로고
    • Intrinsic and extrinsic inhibition of oligodendrocyte development by rat retina
    • Gao L, Macklin W, Gerson J, Miller RH, (2006) Intrinsic and extrinsic inhibition of oligodendrocyte development by rat retina. Dev Biol 290: 277-286.
    • (2006) Dev Biol , vol.290 , pp. 277-286
    • Gao, L.1    Macklin, W.2    Gerson, J.3    Miller, R.H.4
  • 81
    • 77956215592 scopus 로고    scopus 로고
    • Heterogeneity of glia in the retina and optic nerve of birds and mammals
    • Fischer AJ, Zelinka C, Scott MA, (2010) Heterogeneity of glia in the retina and optic nerve of birds and mammals. PLoS One 5: e10774.
    • (2010) PLoS One , vol.5
    • Fischer, A.J.1    Zelinka, C.2    Scott, M.A.3
  • 82
    • 0025238521 scopus 로고
    • Evidence that the lamina cribrosa prevents intraretinal myelination of retinal ganglion cell axons
    • Perry VH, Lund RD, (1990) Evidence that the lamina cribrosa prevents intraretinal myelination of retinal ganglion cell axons. J Neurocytol 19: 265-272.
    • (1990) J Neurocytol , vol.19 , pp. 265-272
    • Perry, V.H.1    Lund, R.D.2
  • 83
    • 0034284392 scopus 로고    scopus 로고
    • NG2-expressing cells in the central nervous system: are they oligodendroglial progenitors?
    • Dawson MR, Levine JM, Reynolds R, (2000) NG2-expressing cells in the central nervous system: are they oligodendroglial progenitors? J Neurosci Res 61: 471-479.
    • (2000) J Neurosci Res , vol.61 , pp. 471-479
    • Dawson, M.R.1    Levine, J.M.2    Reynolds, R.3
  • 84
    • 0036354793 scopus 로고    scopus 로고
    • NG2 proteoglycan expression by pericytes in pathological microvasculature
    • Ozerdem U, Monosov E, Stallcup WB, (2002) NG2 proteoglycan expression by pericytes in pathological microvasculature. Microvasc Res 63: 129-134.
    • (2002) Microvasc Res , vol.63 , pp. 129-134
    • Ozerdem, U.1    Monosov, E.2    Stallcup, W.B.3
  • 85
    • 0034796499 scopus 로고    scopus 로고
    • NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis
    • Ozerdem U, Grako KA, Dahlin-Huppe K, Monosov E, Stallcup WB, (2001) NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis. Dev Dyn 222: 218-227.
    • (2001) Dev Dyn , vol.222 , pp. 218-227
    • Ozerdem, U.1    Grako, K.A.2    Dahlin-Huppe, K.3    Monosov, E.4    Stallcup, W.B.5
  • 86
    • 3242885697 scopus 로고    scopus 로고
    • Characterization of smooth muscle cell and pericyte differentiation in the rat retina in vivo
    • Hughes S, Chan-Ling T, (2004) Characterization of smooth muscle cell and pericyte differentiation in the rat retina in vivo. Invest Ophthalmol Vis Sci 45: 2795-2806.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2795-2806
    • Hughes, S.1    Chan-Ling, T.2
  • 87
    • 37549001401 scopus 로고    scopus 로고
    • Accumulation of macrophage-like cells expressing NG2 proteoglycan and Iba1 in ischemic core of rat brain after transient middle cerebral artery occlusion
    • Matsumoto H, Kumon Y, Watanabe H, Ohnishi T, Shudou M, et al. (2008) Accumulation of macrophage-like cells expressing NG2 proteoglycan and Iba1 in ischemic core of rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 28: 149-163.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 149-163
    • Matsumoto, H.1    Kumon, Y.2    Watanabe, H.3    Ohnishi, T.4    Shudou, M.5
  • 88
    • 71549158808 scopus 로고    scopus 로고
    • NG2, a member of chondroitin sulfate proteoglycans family mediates the inflammatory response of activated microglia
    • Gao Q, Lu J, Huo Y, Baby N, Ling EA, et al. (2010) NG2, a member of chondroitin sulfate proteoglycans family mediates the inflammatory response of activated microglia. Neuroscience 165: 386-394.
    • (2010) Neuroscience , vol.165 , pp. 386-394
    • Gao, Q.1    Lu, J.2    Huo, Y.3    Baby, N.4    Ling, E.A.5
  • 89
    • 77950999159 scopus 로고    scopus 로고
    • Chondroitin Sulfates are Required for FGF-2-dependent Proliferation and Maintenance in Neural Stem Cells and for EGF-dependent Migration of Their Progeny
    • Sirko S, von Holst A, Weber A, Wizenmann A, Theocharidis U, et al. (2010) Chondroitin Sulfates are Required for FGF-2-dependent Proliferation and Maintenance in Neural Stem Cells and for EGF-dependent Migration of Their Progeny. Stem Cells.
    • (2010) Stem Cells
    • Sirko, S.1    von Holst, A.2    Weber, A.3    Wizenmann, A.4    Theocharidis, U.5
  • 90
    • 0033546441 scopus 로고    scopus 로고
    • High-affinity binding of basic fibroblast growth factor and platelet-derived growth factor-AA to the core protein of the NG2 proteoglycan
    • Goretzki L, Burg MA, Grako KA, Stallcup WB, (1999) High-affinity binding of basic fibroblast growth factor and platelet-derived growth factor-AA to the core protein of the NG2 proteoglycan. J Biol Chem 274: 16831-16837.
    • (1999) J Biol Chem , vol.274 , pp. 16831-16837
    • Goretzki, L.1    Burg, M.A.2    Grako, K.A.3    Stallcup, W.B.4
  • 91
    • 11244323919 scopus 로고    scopus 로고
    • Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility
    • Makagiansar IT, Williams S, Dahlin-Huppe K, Fukushi J, Mustelin T, et al. (2004) Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility. J Biol Chem 279: 55262-55270.
    • (2004) J Biol Chem , vol.279 , pp. 55262-55270
    • Makagiansar, I.T.1    Williams, S.2    Dahlin-Huppe, K.3    Fukushi, J.4    Mustelin, T.5
  • 92
    • 3343011406 scopus 로고    scopus 로고
    • NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin
    • Fukushi J, Makagiansar IT, Stallcup WB, (2004) NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin. Mol Biol Cell 15: 3580-3590.
    • (2004) Mol Biol Cell , vol.15 , pp. 3580-3590
    • Fukushi, J.1    Makagiansar, I.T.2    Stallcup, W.B.3
  • 93
    • 78149435065 scopus 로고    scopus 로고
    • The myeloid cells of the central nervous system parenchyma
    • Ransohoff RM, Cardona AE, (2010) The myeloid cells of the central nervous system parenchyma. Nature 468: 253-262.
    • (2010) Nature , vol.468 , pp. 253-262
    • Ransohoff, R.M.1    Cardona, A.E.2
  • 95
    • 0031985336 scopus 로고    scopus 로고
    • Mature microglia resemble immature antigen-presenting cells
    • Carson MJ, Reilly CR, Sutcliffe JG, Lo D, (1998) Mature microglia resemble immature antigen-presenting cells. Glia 22: 72-85.
    • (1998) Glia , vol.22 , pp. 72-85
    • Carson, M.J.1    Reilly, C.R.2    Sutcliffe, J.G.3    Lo, D.4
  • 96
    • 30044434850 scopus 로고    scopus 로고
    • Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells
    • Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, et al. (2006) Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol Cell Neurosci 31: 149-160.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 149-160
    • Butovsky, O.1    Ziv, Y.2    Schwartz, A.3    Landa, G.4    Talpalar, A.E.5
  • 97
    • 18244364861 scopus 로고    scopus 로고
    • Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury
    • Ladeby R, Wirenfeldt M, Dalmau I, Gregersen R, Garcia-Ovejero D, et al. (2005) Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury. Glia 50: 121-131.
    • (2005) Glia , vol.50 , pp. 121-131
    • Ladeby, R.1    Wirenfeldt, M.2    Dalmau, I.3    Gregersen, R.4    Garcia-Ovejero, D.5
  • 98
    • 40049094057 scopus 로고    scopus 로고
    • Microtubule-associated protein 2-positive cells derived from microglia possess properties of functional neurons
    • Matsuda S, Niidome T, Nonaka H, Goto Y, Fujimura K, et al. (2008) Microtubule-associated protein 2-positive cells derived from microglia possess properties of functional neurons. Biochem Biophys Res Commun 368: 971-976.
    • (2008) Biochem Biophys Res Commun , vol.368 , pp. 971-976
    • Matsuda, S.1    Niidome, T.2    Nonaka, H.3    Goto, Y.4    Fujimura, K.5
  • 99
    • 22144469451 scopus 로고    scopus 로고
    • Co-expression of radial glial marker in macrophages/microglia in rat spinal cord contusion injury model
    • Wu D, Miyamoto O, Shibuya S, Mori S, Norimatsu H, et al. (2005) Co-expression of radial glial marker in macrophages/microglia in rat spinal cord contusion injury model. Brain Res 1051: 183-188.
    • (2005) Brain Res , vol.1051 , pp. 183-188
    • Wu, D.1    Miyamoto, O.2    Shibuya, S.3    Mori, S.4    Norimatsu, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.