Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559

Molecular Pain

Volumn 7, Issue , 2011, Pages

  Cheng, Long Zhen ^a   Han, Lei ^a   Fan, Jing ^a   Huang, Lan Ting ^a   Peng, Li Chao ^a   Wang, Yun ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

4 2 nAChRs; CCI; Formalin test; Pain; sIPSCs; Spinal cord slice; TC 2559

Indexed keywords

NICOTINIC AGENT; NICOTINIC RECEPTOR ALPHA4BETA2; TC 2559; UNCLASSIFIED DRUG; ANALGESIC AGENT; FORMALDEHYDE; NICOTINIC RECEPTOR; PYRIDINE DERIVATIVE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BRAIN LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VIVO STUDY; MALE; NEUROPATHIC PAIN; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION; ANIMAL; BIOAVAILABILITY; BRAIN; DRUG EFFECT; IN VITRO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; MOUSE; NEURALGIA; NOCICEPTION; PATHOLOGY; PATHOPHYSIOLOGY; POSTERIOR HORN CELL; SPRAGUE DAWLEY RAT; STENOSIS, OCCLUSION AND OBSTRUCTION;

ANALGESICS; ANIMALS; BIOLOGICAL AVAILABILITY; BRAIN; CONSTRICTION, PATHOLOGIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FORMALDEHYDE; INHIBITORY POSTSYNAPTIC POTENTIALS; MALE; MICE; NEURALGIA; NOCICEPTION; POSTERIOR HORN CELLS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC;

EID: 79961118232     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-7-56     Document Type: Article

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