Early senescence is not an inevitable fate of human-induced pluripotent stem-derived cells

Cellular Reprogramming

Volumn 13, Issue 4, 2011, Pages 361-370

  Gokoh, Maiko ^a   Nishio, Miwako ^a   Nakamura, Naoko ^a   Matsuyama, Satoko ^a   Nakahara, Masako ^a   Suzuki, Shinnosuke ^a   Mitsumoto, Masami ^a   Akutsu, Hidenori ^b   Umezawa, Akihiro ^b   Yasuda, Kazuki ^a   Yuo, Akira ^a   Saeki, Kumiko ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b National Research Institute   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RETROVIRUS VECTOR;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; HEMANGIOBLAST; HEMATOPOIESIS; HUMAN; HUMAN CELL; NEUTROPHIL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SENESCENCE;

CELL AGING; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; FEEDER CELLS; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS;

EID: 79961096435     PISSN: 21524971     EISSN: 21524998     Source Type: Journal    
DOI: 10.1089/cell.2011.0004     Document Type: Article

References (26)

1. Draper, J. S., Smith, K., Gokhale, P., et al. (2004). Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat. Biotechnol. 22, 53-54. (Pubitemid 38057956)
2. Eilken, H. M., Nishikawa, S., and Schroeder, T. (2009). Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature 457, 896-900.
3. Feng, Q., Lu, S. J., Klimanskaya, I., et al. (2010). Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence. Stem Cells 28, 704-712.
4. Fusaki, N., Ban, H., Nishiyama, A., et al. (2009). Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc. Jpn. Acad. Ser. B Phys. Biol. Sci. 85, 348-362.
5. Kaji, K., Norrby, K., Paca, A., et al. (2009). Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458, 771-775.
6. Kim, D., Kim, C. H., Moon, J. I., et al. (2009). Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472-476.
7. Mitalipova, M. M., Rao, R. R., Hoyer, D. M., et al. (2005). Preserving the genetic integrity of human embryonic stem cells. Nat. Biotechnol. 23, 19-20. (Pubitemid 41724618)
8. Miura, K., Okada, Y., Aoi, T., et al. (2009). Variation in the safety of induced pluripotent stem cell lines. Nat. Biotechnol. 27, 743-745.
9. Nakagawa, M., Koyanagi, M., Tanabe, K., et al. (2008). Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26, 101-106.
10. Nakagawa, M., Takizawa, N., Narita, M., et al. (2010). Promotion of direct reprogramming by transformation-deficient Myc. Proc. Natl. Acad. Sci. USA 107, 14152-14157.
11. Nakahara, M., Nakamura, N., Matsuyama, S., et al. (2009). Highefficiency production of subculturable vascular endothelial cells from feeder-free human embryonic stem cells without cell-sorting technique. Cloning Stem Cells 11, 509-522.
12. Nelson, T. J., Martinez-Fernandez, A., Yamada, S., et al. (2009). Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation 120, 408-416.
13. Okita, K., Ichisaka, T., and Yamanaka, S. (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317. (Pubitemid 47080336)
14. Okita, K., Nakagawa, M., Hyenjong, H., et al. (2008). Generation of mouse induced pluripotent stem cells without viral vectors. Science 322, 949-953.
15. Osafune, K., Caron, L., Borowiak, M., et al. (2008). Marked differences in differentiation propensity among human embryonic stem cell lines. Nat. Biotechnol. 26, 313-315. (Pubitemid 351355125)
16. Saeki, K., Yogiashi, Y., Nakahara, M., et al. (2008). Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells. J. Cell Physiol. 217, 261-280.
17. Saeki, K., Saeki, K., Nakahara, M., et al. (2009). A feeder-free and efficient production of functional neutrophils from human embryonic stem cells. Stem Cells 27, 59-67.
18. Seki, T., Yuasa, S., Oda, M., et al. (2010). Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell, 7, 11-14.
19. Suemori, H., Yasuchika, K., Hasegawa, K., et al. (2006). Efficient establishment of human embryonic stem cell lines and longterm maintenance with stable karyotype by enzymatic bulk passage. Biochem. Biophys. Res. Commun. 345, 926-932. (Pubitemid 43776486)
20. Takahashi, K., Tanabe, K., Ohnuki, M., et al. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872. (Pubitemid 350138099)
21. Tesar, P. J., Chenoweth, J. G., Brook, F. A., et al. (2007). New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448, 196-199. (Pubitemid 47067378)
22. Vallier, L., Touboul, T., Chng, Z., et al. (2009). Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways. PLoS One 4, e6082.
23. Warren, L., Manos, P. D., Ahfeldt, T., et al. (2010). Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7, 618-630.
24. Woltjen, K., Michael, I. P., Mohseni, P., et al. (2009). piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770.
25. Yu, J., Hu, K., Smuga-Otto, K., et al. (2009). Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797-801.
26. Zhou, H., Wu, S., Joo, J. Y., et al. (2009). Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4, 381-384.