Dual mechanisms of action of the retinoid CD437: Nuclear retinoic acid receptor-mediated suppression of squamous differentiation and receptor-independent induction of apoptosis in UMSCC22B human head and neck squamous cell carcinoma cells

Molecular Pharmacology

Volumn 58, Issue 3, 2000, Pages 508-514

  Sun, Shi Yong ^a   Yue, Ping ^a   Chandraratna, Roshantha A S ^b   Tesfaigzi, Yohannes ^c   Hong, Waun K ^a   Lotan, Reuben ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b ALLERGAN INC   (United States)

^c LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL)BENZO[B]THIOPHENE 6 CARBOXYLIC ACID; 3,5 DI TERT BUTYL 4' CHALCONECARBOXYLIC ACID; 4 [2 [5,6 DIHYDRO 5,5 DIMETHYL 8 (4 METHYLPHENYL) 2 NAPHTHYL]ETHYNYL]BENZOIC ACID; 5,6,7,8 TETRAHYDRO 3,5,5,8,8 PENTAMETHYL 2 NAPHTHOIC ACID 4 CARBOXYPHENYL ESTER; 6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; ADAPALENE; AGN 193078; AGN 193273; CD 2325; CD 666; RETINOIC ACID; RETINOIC ACID DERIVATIVE; RETINOIC ACID RECEPTOR; SR 3985; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

EID: 0033863835     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.3.508     Document Type: Article

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