Proteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP5+

International Journal of Radiation Oncology Biology Physics

Volumn 78, Issue 2, 2010, Pages 547-554

  Yakovlev, Vasily A ^a   Rabender, Christopher S ^b   Sankala, Heidi ^a   Gauter Fleckenstein, Ben ^c,d   Fleckenstein, Katharina ^c,d   Batinic Haberle, Ines ^d   Jackson, Isabel ^d   Vujaskovic, Zeljko ^d   Anscher, Mitchell S ^a   Mikkelsen, Ross B ^a   Graves, Paul R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Heme oxygenase; Inflammation; Proteomics; Radiation induced lung injury; Superoxide dismutase

Indexed keywords

HEME OXYGENASES; INFLAMMATION; PROTEOMICS; RADIATION-INDUCED LUNG INJURY; SUPER OXIDE DISMUTASE;

CELL DEATH; DEGRADATION; IRRADIATION; LOSS PREVENTION; MANGANESE; MOLECULAR BIOLOGY; OXYGEN; PATHOLOGY; PHOSPHORYLATION; PORPHYRINS; PROTEINS; RADIATION; RATS;

BIOLOGICAL ORGANS;

BETA CATENIN; BILIVERDIN; CASPASE 3; CASPASE 9; FILAMIN A; HEME OXYGENASE 1; LIPOCORTIN 2; PEROXIREDOXIN 2; SUPEROXIDE DISMUTASE; TALIN; ACTIN BINDING PROTEIN; BILIVERDIN REDUCTASE; CONTRACTILE PROTEIN; FILAMIN; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; MANGANESE (III) MESO-TETRAKIS(N-ETHYLPYRIDINIUM-2-YL)PORPHYRIN; MESSENGER RNA; METALLOPORPHYRIN; OXIDOREDUCTASE; PEROXIREDOXIN; PROTEIN; PROTEIN KINASE B; RADIOPROTECTIVE AGENT; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; ENZYME PHOSPHORYLATION; FEMALE; IMMUNOPRECIPITATION; IRRADIATION; LUNG INJURY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RADIATION PROTECTION; RAT; STRESS; WESTERN BLOTTING; ANIMAL; DOWN REGULATION; DRUG EFFECTS; FISCHER 344 RAT; LUNG; METABOLISM; RADIATION DOSE; RADIATION INJURIES, EXPERIMENTAL; RADIATION RESPONSE; TIME;

ANIMALS; ANNEXIN A2; APOPTOSIS; BETA CATENIN; CASPASE 9; CONTRACTILE PROTEINS; DOWN-REGULATION; FEMALE; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; HEME OXYGENASE-1; LUNG; METALLOPORPHYRINS; MICROFILAMENT PROTEINS; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PEROXIREDOXINS; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION DOSAGE; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RATS; RATS, INBRED F344; RNA, MESSENGER; TALIN; TIME FACTORS; FILAMINS; RHO-SPECIFIC GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS;

EID: 79961065244     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.03.037     Document Type: Article

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