Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: Key role in the osmotically triggered F-actin response

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 3, 2009, Pages

  Thirone, Ana C P ^a   Speight, Pam ^a   Zulys, Matthew ^a   Rotstein, Ori D ^a   Szászi, Katalin ^a   Pedersen, Stine F ^b   Kapus, András ^a  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Cell volume; Cytoskeleton; Hypertonicty; Small GTPases

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; COFILIN; F ACTIN; HYPERTONIC SOLUTION; LIM KINASE; RHO FACTOR; RHO KINASE; SMALL INTERFERING RNA; ACTIN; COFILIN 1; P21 ACTIVATED KINASE; PROTEIN KINASE INHIBITOR; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; FEMALE; HYPEROSMOLARITY; HYPEROSMOTIC STRESS; KIDNEY TUBULE CELL; NONHUMAN; OSMOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; CELL SIZE; CELL STRAIN; DOG; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; KIDNEY TUBULE; KINETICS; METABOLISM; MUTATION; OSMOTIC PRESSURE; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SWINE; TUMOR CELL LINE;

ACTINS; ANIMALS; CELL LINE, TUMOR; CELL SIZE; COFILIN 1; DOGS; HYPERTONIC SOLUTIONS; KIDNEY TUBULES; KINETICS; LIM KINASES; LLC-PK1 CELLS; MUTATION; OSMOTIC PRESSURE; P21-ACTIVATED KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RAC GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SWINE; TRANSFECTION;

EID: 65249132407     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00467.2008     Document Type: Article

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