Metabolomics study of alcohol-induced liver injury and hepatocellular carcinoma xenografts in mice

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 24, 2011, Pages 2369-2375

  Li, Shangfu ^a   Liu, Hongxia ^a,b   Jin, Yibao ^a   Lin, Shuhai ^c   Cai, Zongwei ^b,c   Jiang, Yuyang ^a,d  

^a TSINGHUA UNIVERSITY   (China)

^b Key Laboratory of Tumor Metabonomics at Shenzhen City   (China)

^c HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^d Tsinghua University   (China)

Author keywords

Alcohol liver injury; Hepatocellular carcinoma xenograft; Liquid chromatography mass spectrometry; Metabolomics; Phospholipid

Indexed keywords

ALCOHOL ABUSE; HEPATOCELLULAR CARCINOMA; HEPG2 CELLS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LIVER DISEASE; LIVER INJURIES; METABOLIC CHANGES; METABOLOMICS; NUDE MICE; PARTIAL LEAST SQUARES-DISCRIMINANT ANALYSIS; PHOSPHATIDYLCHOLINE; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; SERUM SAMPLES; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY;

BODY FLUIDS; DISCRIMINANT ANALYSIS; FATTY ACIDS; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES; MONOUNSATURATED FATTY ACIDS; PHOSPHOLIPIDS; POLYUNSATURATED FATTY ACIDS; PRINCIPAL COMPONENT ANALYSIS;

MAMMALS;

BIOLOGICAL MARKER; LYSOPHOSPHATIDYLCHOLINE; MONOUNSATURATED FATTY ACID; PHOSPHATIDYLCHOLINE; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID;

ALCOHOL LIVER CIRRHOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; HUMAN; HUMAN CELL; LIQUID; LIVER CELL CARCINOMA; LIVER DISEASE; MALE; METABOLITE; METABOLOMICS; MOUSE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; TUMOR XENOGRAFT; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CHROMATOGRAPHY, LIQUID; DISEASE MODELS, ANIMAL; ETHANOL; FATTY LIVER, ALCOHOLIC; HUMANS; LIPID METABOLISM; LIPIDS; LIVER; LIVER NEOPLASMS; MALE; MASS SPECTROMETRY; METABOLOMICS; MICE; MICE, NUDE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; MUS MUSCULUS;

EID: 79960993083     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.06.018     Document Type: Article

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